Abstract：
PURPOSE:To report corneal histopathology associated with keratectasia after laser in situ keratomileusis (LASIK) and to evaluate the thickness of the calculated residual stromal bed in two cases and those in the literature. DESIGN:Interventional case reports. METHODS:Three eyes of two patients developed keratectasia after LASIK. Corneal specimens after penetrating keratoplasty in one eye of each patient were studied histopathologically, and the residual stromal bed was directly measured. For comparison, residual stromal bed thicknesses were calculated from published cases of keratectasia. RESULTS:Two eyes of a 26-year-old woman and one eye of a 22-year-old woman developed keratectasia after LASIK. Calculated residual stromal bed thicknesses were 210, 213, and 261 microm. Histologic sections revealed focal scarring in the flap plane. The cornea specimens measured 75 and 118 microm thinner than calculated values immediately after LASIK. Transmission electron microscopy of one case revealed an average lamellar thickness of 0.94 microm. In 28 (49%) of 57 previous cases of keratectasia, the calculated residual stromal bed thicknesses were greater than 250 microm. CONCLUSIONS:Both the flap and the stromal bed of the cornea may thin after LASIK. A residual stromal bed thickness of 250 microm does not preclude the development of keratectasia after LASIK.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Ou RJ,Shaw EL,Glasgow BJdoi
10.1016/s0002-9394(02)01656-2subject
Has Abstractpub_date
2002-11-01 00:00:00pages
771-3issue
5eissn
0002-9394issn
1879-1891pii
S0002939402016562journal_volume
134pub_type
杂志文章abstract：PURPOSE:To present a quantitative analysis of pterygium and ocular sun exposure, a dose-response curve, and a discussion of the health-promotion implications of the findings. METHODS:A hospital-based, case-control study was conducted in Perth, Western Australia. Case subjects had surgical removal of a pterygium; contr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00161-0
更新日期：1999-09-01 00:00:00
abstract：:We used monoclonal antibodies against specific T cell, B cell, and macrophage antigens to detect immune system cells in the vitreous gel of retinitis pigmentosa patients. Vitreous samples were obtained by biopsy from three patients and by dissection from eight postmortem donor eyes. All samples contained CD4, T helper...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(88)90050-5
更新日期：1988-06-15 00:00:00
abstract：PURPOSE:To characterize features of glaucoma associated with a TANK binding kinase 1 (TBK1) gene duplication, which is among the most common molecularly defined causes of normal tension glaucoma (NTG). DESIGN:Retrospective observational case series. METHODS:We conducted a retrospective case series, by reviewing medic...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.01.017
更新日期：2020-06-01 00:00:00
abstract：:We obtained serial electroretinograms in four patients aged between 6 months and 5 years with Alström's syndrome and studied the early stages of the severe retinopathy that is characteristic of that disease. The weak electroretinographic signals found at age 6 months demonstrate a severe early cone dysfunction; one ye...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71466-7
更新日期：1993-05-15 00:00:00
abstract：PURPOSE:To demonstrate that hairy cell leukemia may involve the eye. METHODS:We examined a patient who had a unique ocular manifestation of hairy cell leukemia with severe panuveitis in one eye and leukemic retinopathy in the fellow eye. RESULTS:Therapy with 2-chloro-deoxy-adenosine, a drug recently introduced for tr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70543-4
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:To assess the role of muscular degeneration, we evaluated the correlation between ptosis severity and levator muscle function. DESIGN:Retrospective cohort study. METHODS:The medical records of 136 patients (53 men and 83 women; mean age, 67 years) with acquired blepharoptosis were reviewed for levator functio...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.02.002
更新日期：2008-06-01 00:00:00
abstract：:We analyzed two consecutive series of cataract extractions in patients with moderate to severe myopia for the incidence of postoperative retinal detachment. One series consisted of 122 intracapsular cataract extractions without surgical loss of vitreous and the other series consisted of 151 extracapsular (phacoemulsif...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(84)90445-8
更新日期：1984-01-01 00:00:00
abstract：PURPOSE:To investigate long-term responsiveness of patients with severe uveitis associated with Behçet disease to interferon alpha2a (IFN-alpha2a). DESIGN:Retrospective study. METHODS:Thirty-two patients with sight-threatening uveitis associated with Behçet disease who relapsed despite corticosteroids and immunosuppr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.08.038
更新日期：2008-12-01 00:00:00
abstract：:Induced prolonged complementary chromatopsia in four subjects (two men, 26 and 34 years old, and two women, 34 and 45 years old) was documented by abnormal responses to pseudoisochromatic color plates 30 minutes after cessation of monochrome video display terminal use. This phenomenon was unrelated to preexisting colo...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(84)90694-9
更新日期：1984-12-15 00:00:00
abstract：:The prevalence of diabetic retinopathy was lower in a rural diabetic population when compared to the prevalence of diabetic retinopathy in medical center clinic populations. Adult-onset (Type II) diabetics were at greater risk for developing diabetic retinopathy shortly after diagnosis than newly diagnosed cases of ju...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(84)90502-6
更新日期：1984-06-01 00:00:00
abstract：PURPOSE:To report long-term anatomical and functional results after pars plana vitrectomy with peeling of the internal limiting membrane (ILM) for idiopathic macular hole. DESIGN:Prospective, nonrandomized, consecutive series. METHODS:Ninety-nine patients with a follow-up of at least 12 months were included. The surg...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01751-8
更新日期：2002-11-01 00:00:00
abstract：:Fifteen patients with malignant epithelial tumors of the conjunctiva were treated with beta-ray ocular applicators filled with radioactive strontium and yttrium (90Sr/90Y). Histologic examination confirmed the diagnosis. There were ten squamous cell carcinomas, four carcinomas in situ, and one case of epidermidalizati...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/0002-9394(76)90731-5
更新日期：1976-02-01 00:00:00
abstract：PURPOSE:To evaluate the use of disk diameter as an indicator in the identification of glaucomatous optic neuropathy. METHODS:We evaluated all available stereofundus photographs for 1,040 right eyes obtained in the Reykjavik Eye Study. Horizontal and vertical disk diameters were determined in a masked manner by a glauc...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01928-1
更新日期：2003-02-01 00:00:00
abstract：PURPOSE:To investigate whether retina damaged in the process of air/fluid exchange could be visualized in situ using trypan blue staining. METHODS:Vitrectomy and air/fluid exchange with continuous air infusion for various periods of time was performed in adult pigmented rabbits, followed by injection of 0.4% trypan bl...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00927-2
更新日期：2001-06-01 00:00:00
abstract：PURPOSE:To determine whether central corneal thickness (CCT) is a risk factor for visual field loss development among patients diagnosed with preperimetric glaucomatous optic neuropathy (GON). DESIGN:Observational cohort study. METHODS:The study included 98 eyes of 98 patients with GON, with a mean follow-up time of ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(03)00484-7
更新日期：2003-11-01 00:00:00
abstract：:A patient with X-chromosome-linked recessive Norrie's disease, characterized by retinal falciform fold, retinal detachment, repeated vitreous hemorrhage, and retrolental membrane formation, was observed from age 6 weeks. The patient showed the clinical progression from these early retinal and vitreous changes to the m...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75079-2
更新日期：1980-07-01 00:00:00
abstract：PURPOSE:To report the population-based birth prevalence of pseudostrabismus in the first year of life and the subsequent diagnosis of strabismus. DESIGN:Retrospective population-based cohort study. METHODS:All residents of Olmsted County, Minnesota ≤1 year old diagnosed with pseudostrabismus from January 1, 2005 thro...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.06.002
更新日期：2020-10-01 00:00:00
abstract：PURPOSE:To evaluate possible changes in macular morphology after cataract surgery with combined primary posterior capsulorhexis and posterior optic buttonholing in comparison to conventional in-the-bag intraocular lens (IOL) implantation. DESIGN:Prospective randomized study. METHODS:Fifty consecutive age-related cata...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajo.2008.02.022
更新日期：2008-07-01 00:00:00
abstract：PURPOSE:To compare polymerase chain reaction (PCR) results to presumptive clinical diagnosis in patients with vitritis. DESIGN:Retrospective review of PCR laboratory records from vitreous samples. METHODS:Fifty consecutive laboratory records of vitreous samples sent for PCR testing were reviewed. Three reviewers with...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.10.011
更新日期：2006-03-01 00:00:00
abstract：:Corneal epithelial iron lines commonly occur, and their shape is characteristically influenced by the underlying corneal surface topography. We studied a pattern of iron deposition, observed after implantation of the Intrastromal Corneal Ring (KeraVision, Inc., Santa Clara, California). In five of ten patients undergo...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1016/s0002-9394(14)71353-4
更新日期：1993-09-15 00:00:00
abstract：:We treated 84 patients with a partially refractive accommodative esotropia with bifocals. Twelve patients were able to fuse without bifocals at the end of therapy; in 19, the bifocal power could be reduced and further improvement can be expected in the future. Thirty-nine remained dependent on bifocals; and in 14, fus...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)78113-9
更新日期：1978-06-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1986-12-15 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(87)90220-0
更新日期：1987-10-15 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(01)01024-8
更新日期：2001-09-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.11.011
更新日期：2005-04-01 00:00:00
abstract：:We analyzed 34 sets of optic disk photographs from 19 patients with glaucoma who had been followed up for ten years to evaluate changes in the position of the vasculature of the optic disks over time. Each photograph was analyzed by an image analyzer's edge-defining program for optic disk analysis and by three experie...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74101-7
更新日期：1987-11-15 00:00:00
abstract：:Eight patients with severe traumatic hyphemas underwent clot evacuation with vitrectomy instrumentation. The patients were followed up for periods of one to four years. No significant intraoperative complications were noted, but one eye developed a postoperative flat anterior chamber and another developed multiple sta...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(79)90574-9
更新日期：1979-11-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2010.02.026
更新日期：2010-08-01 00:00:00
abstract：PURPOSE:To assess the results of iris suture fixation of subluxated intraocular lenses. DESIGN:Retrospective study. METHODS:This was a nonrandomized chart review of eyes with subluxated intraocular lenses that underwent iris suture fixation at an academic institutional care center. Seventy-two eyes of 67 consecutive ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2014.11.009
更新日期：2015-02-01 00:00:00
abstract：:The flat, circumscribed, and hyperpigmented lesion of the retinal pigment epithelium (RPE) without clinically apparent involvement of the overlying retina, designated as congenital hypertrophy, was found to be associated with corresponding scotomas in the visual field. The depth of the scotoma increased with the age o...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90069-0
更新日期：1975-02-01 00:00:00
