Abstract:
PURPOSE:To report the association of antiretinal antibodies in patients with bilateral cystoid macular edema and retinitis pigmentosa. METHODS:In a prospective study, 30 consecutive patients with bilateral cystoid macular edema and retinitis pigmentosa were tested for antiretinal antibodies. As control subjects, 30 consecutive patients with retinitis pigmentosa who did not have cystoid macular edema and 50 normal subjects without retinitis pigmentosa or cystoid macular edema were tested for antiretinal antibodies. Laboratory personnel performing the antiretinal antibody testing were masked regarding the diagnosis of each patient. RESULTS:Twenty-seven (90%) of 30 patients with retinitis pigmentosa with cystoid macular edema had antiretinal protein antibody activity, compared with three (6%) of 50 normal controls (P < .001) and only four (13%) of 30 control patients with retinitis pigmentosa (P < .001). CONCLUSIONS:We found a significant association between cystoid macular edema and the presence of circulating antiretinal antibodies in patients who presented with retinitis pigmentosa and cystoid macular edema. This study suggests that patients with retinitis pigmentosa with cystoid macular edema may have an autoimmune process that is contributing to the formation of cystoid macular edema in retinitis pigmentosa, but to date, there is no direct evidence that the cystoid macular edema is caused by the antiretinal antibodies.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Heckenlively JR,Jordan BL,Aptsiauri Ndoi
10.1016/s0002-9394(98)00446-2subject
Has Abstractpub_date
1999-05-01 00:00:00pages
565-73issue
5eissn
0002-9394issn
1879-1891pii
S0002939498004462journal_volume
127pub_type
杂志文章abstract:PURPOSE:To identify nationwide trends and factors associated with advanced imaging (computed tomography [CT] and magnetic resonance imaging [MRI]) use for eye-related emergency department (ED) visits. DESIGN:Retrospective, trend study. METHODS:Setting: National Hospital Ambulatory Medical Care Survey 2007-2015. PATI...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2019.11.007
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:To correlate in vivo imaging to histology in an eye with macular atrophy owing to age-related macular degeneration (AMD; complete retinal pigment epithelium [RPE] and outer retinal atrophy [cRORA]) to evaluate the utility of new optical coherence tomography (OCT) suggested by previous histology. DESIGN:Case st...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.06.020
更新日期:2018-09-01 00:00:00
abstract::A small piece of Ping-Pong ball material fitted to a Burian-Allen contact lens electrode provided a large field of evenly distributed light on the retina that resulted in larger electroretinographic amplitudes and more accurate measurement of b-wave latencies. ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(75)90148-8
更新日期:1975-08-01 00:00:00
abstract:PURPOSE:To report a case of progressive necrotizing fasciitis of the face following acute dacryocystitis. DESIGN:Interventional case report. METHODS:A 60-year-old woman presented with left acute dacryocystitis with abscess formation that had ruptured; a small wound remained. Erythematous swelling of the left eyelid a...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00089-8
更新日期:2003-07-01 00:00:00
abstract:PURPOSE:To report a case of pityriasis rubra pilaris (PRP)-induced bilateral lower eyelid cicatricial ectropion that resolved with systemic low-dose methotrexate. DESIGN:Observational case report. METHODS:A retrospective case review of a patient with cicatricial ectropion caused by PRP. RESULTS:A 82-year-old female ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.11.038
更新日期:2007-04-01 00:00:00
abstract:PURPOSE:To perform a cross-sectional study on the distribution of central corneal thickness and its association with intraocular pressure in an elderly population. METHODS:We measured central corneal thickness and intraocular pressure in 395 subjects (352 control subjects, 13 patients with ocular hypertension, and 30 ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71125-0
更新日期:1997-06-01 00:00:00
abstract:PURPOSE:To determine the etiologies and management of calcific band keratopathy (CBK), and assess the results and long-term follow-up after ethylenediamine-tetraacetic acid (EDTA) chelation. DESIGN:Retrospective interventional case series. METHODS:Two hundred thirty patients with clinically significant CBK were inclu...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.01.036
更新日期:2004-06-01 00:00:00
abstract:PURPOSE:To assess the risk of diabetic retinopathy (DR) in children with type 1 diabetes mellitus (T1DM) diagnosed at a very early age. DESIGN:Observational case series. METHODS:The records of 51 patients were identified through the diabetes database of the Division of Pediatric Endocrinology and Metabolism at Washin...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.05.023
更新日期:2005-11-01 00:00:00
abstract:PURPOSE:To measure the change of peripapillary retinal vessel density (VD) in eyes with a history of acute primary angle-closure glaucoma (PACG). DESIGN:Case-control study. METHODS:Twenty-one consecutive Chinese patients with history of unilateral acute PACG were enrolled. Eyes with acute PACG constituted the case gr...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2017.07.024
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:Distance stereoacuity is used to monitor deterioration of intermittent exotropia (IXT), but variability of stereoacuity has not been studied rigorously. The purpose of this study was to assess the variability of stereoacuity over one day in children with IXT. DESIGN:Prospective cohort study. METHODS:Twelve ch...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2007.10.028
更新日期:2008-03-01 00:00:00
abstract::Conjunctivodacryocystorhinostomy with a Jones tube is an accepted procedure for the treatment of epiphora resulting from obstructed canaliculi. Because of our clinical impression that a high rate of functional success after surgery is associated with a lower rate of patient satisfaction, we analyzed the results and pa...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70070-4
更新日期:1994-05-15 00:00:00
abstract:PURPOSE:To report a young girl with spontaneous separation of an idiopathic epiretinal membrane and notable visual recovery. METHOD:Case report. RESULT:A 12-year-old girl had spontaneous improvement in visual acuity of the left eye from 20/100 to 20/40 attributable to spontaneous peeling of an idiopathic epiretinal m...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(99)00021-5
更新日期:1999-06-01 00:00:00
abstract:PURPOSE/METHODS:Central retinal artery occlusion occurs infrequently in children. We treated a child with central retinal artery occlusion before a systemic disease was discovered. RESULTS/CONCLUSION:Vision improved after paracentesis and anticoagulation. Systemic T-cell lymphoma was subsequently diagnosed. In contras...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73772-9
更新日期:1995-07-01 00:00:00
abstract:PURPOSE:To conduct a qualitative description of corneal and glaucoma outcomes in Peters anomaly. DESIGN:Retrospective case series. METHODS:Children with Peters anomaly who presented between 1982-2017 were included. Visual acuity, intraocular pressure (IOP), survival of corneal grafts, and success of glaucoma surgery ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2019.08.012
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:To determine the origin of scleritis, uveitis, and glaucoma in a boy with fever, sore throat, joint pains, and malaise. METHODS:The patient underwent extensive hematologic, serologic, rheumatologic, and radiologic examinations. RESULTS:The patient recovered after extensive medical therapy. He met the Jones cr...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)72676-5
更新日期:1995-10-01 00:00:00
abstract:PURPOSE:To evaluate the possible toxicity of indocyanine green (ICG) dye in macular hole surgery by comparing functional results after successful surgeries performed with and without staining. DESIGN:Prospective observational case series. METHODS:In a study conducted at our department, 30 eyes of 29 patients with idi...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.05.054
更新日期:2006-11-01 00:00:00
abstract:PURPOSE/METHODS:We studied a case of an aggressive iris nevus that caused secondary glaucoma in a child. RESULTS/CONCLUSION:Unlike most iris tumors, this tumor grew from the superior aspect of the iris. The nevus was also unusual because it invaded the trabecular meshwork and caused secondary glaucoma. ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71184-5
更新日期:1995-03-01 00:00:00
abstract:PURPOSE:To characterize perifoveal intraretinal cavities observed around full-thickness macular holes (MH) using en face optical coherence tomography and to establish correlations with histology of human and primate maculae. DESIGN:Retrospective nonconsecutive observational case series. METHODS:Macular en face scans ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2015.02.013
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:To determine the incidence of Graves' ophthalmopathy. METHODS:A population-based cohort of all Olmsted County, Minnesota, residents who had ophthalmopathy associated with autoimmune thyroid disease between Jan. 1, 1976, and Dec. 31, 1990, was identified through the medical diagnostic index of the Mayo Clinic a...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)72666-2
更新日期:1995-10-01 00:00:00
abstract:PURPOSE:To investigate the effect of yellow-tinted intraocular lenses (IOLs) on short-wavelength automated perimetry (SWAP). DESIGN:Cross-sectional observation study. METHODS:Twenty-two patients who had implantation of yellow-tinted IOLs (AcrySof SN60AT or SN60WF; Alcon Laboratories) in 1 eye and nontinted IOLs (Acry...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2010.02.023
更新日期:2010-08-01 00:00:00
abstract:PURPOSE:To investigate the characteristics, mergers, and risk factors of different types of myopic maculopathy (MM) in a highly myopic population. DESIGN:Population-based, cross-sectional study. METHODS:A total of 1086 eyes (762 patients) were enrolled. Each participant underwent detailed ocular examinations. Combini...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2019.07.010
更新日期:2019-12-01 00:00:00
abstract::A 4-year-old boy had a case of ischemic infarction of the retina that occurred immediately after percutaneous carotoid angiography via a femoral percutaneous approach. This appears to be the youngest reported patient with this complication. ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90203-8
更新日期:1976-01-01 00:00:00
abstract::The effect of rapid freezing and thawing was tested in vitro on 100 human hard nuclear cataracts before ultrasonic emulsification. After phacocryolysis the interspace between lens fibers increased, and the normally closely packed fibers appeared to loosen. This seemed to soften the hard cataract, thereby facilitating ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(77)90906-0
更新日期:1977-06-01 00:00:00
abstract:PURPOSE:We evaluated quantitatively, with electromyography, the function of orbicularis oculi muscle flaps in modified Hughes reconstructions of the lower eyelids. METHODS:A modified Hughes procedure with a bipedicle orbicularis oculi flap was used to reconstruct large left lower eyelid defects after tumor excision in...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73877-2
更新日期:1995-02-01 00:00:00
abstract::A microsurgical modification of the Rizzuti scleral fixation forceps for corneal and cataract surgery employs Bonn 0.12-mm teeth on an angled handle with an appropriate curve between the teeth to fix the tissue more adequately to allow accurate placement of sutures. ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90077-5
更新日期:1976-12-01 00:00:00
abstract:PURPOSE:To determine the clinical value and relevance of punctal and proximal canalicular stenoses after punctal plug therapy in moderate to severe dry eye syndrome. DESIGN:Retrospective, observational case series. METHODS:Seventeen eyes were determined to have punctum or proximal canalicular stenoses after spontaneo...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2008.06.028
更新日期:2008-12-01 00:00:00
abstract:PURPOSE:To demonstrate that hairy cell leukemia may involve the eye. METHODS:We examined a patient who had a unique ocular manifestation of hairy cell leukemia with severe panuveitis in one eye and leukemic retinopathy in the fellow eye. RESULTS:Therapy with 2-chloro-deoxy-adenosine, a drug recently introduced for tr...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70543-4
更新日期:1996-01-01 00:00:00
abstract:PURPOSE:To evaluate visual and optical quality of the implantable collamer lens for different powers and sizes of incision surgery. DESIGN:Prospective study in humans. METHODS:An adaptive optics visual simulator was used to measure 3 powers of implantable collamer lenses and simulate the implantable collamer lens wav...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2012.09.031
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:Periocular injection of corticosteroids is a common treatment for vision loss in patients with intermediate uveitis. However, this treatment has the potential for serious side effects. We sought to determine the effects of such injections in a series of patients. METHODS:We reviewed charts of 20 consecutive pa...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73759-6
更新日期:1995-07-01 00:00:00
abstract:PURPOSE:To evaluate and compare the recovery of postoperative corneal sensitivity after laser in situ keratomileusis and photorefractive keratectomy for the correction of low myopia. METHODS:In a prospective study, 17 consecutive eyes (17 patients) underwent laser in situ keratomileusis to correct myopia ranging from ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00444-9
更新日期:1999-05-01 00:00:00