Flexible neural representations of value in the primate brain.

abstract：:Clara cell protein (CC16 or CC10) is a 15.8-kDa protein secreted all along the tracheobronchial tree and especially in the terminal bronchioles where Clara cells are localized. Even though the exact in vivo function of CC16 remains to be clarified, evidence is accumulating that CC16 plays an important protective role ...

journal_title：Annals of the New York Academy of Sciences

authors： Broeckaert F,Clippe A,Knoops B,Hermans C,Bernard A

更新日期：2000-01-01 00:00:00

abstract：:This review aims to discuss the neurophysiology of the esophagus and new methods to assess esophageal nociception. Pain and other symptoms can be caused by diseases in the mucosa or muscular or sphincter dysfunction, together with abnormal pain processing, either in the peripheral or central nervous systems. Therefore...

journal_title：Annals of the New York Academy of Sciences

authors： Brock C,McCallum RW,Gyawali CP,Farmer AD,Frøkjaer JB,McMahon BP,Drewes AM

更新日期：2016-09-01 00:00:00

abstract：:Immunoglobulin 4 (IgG4) is one of four human IgG subclasses and has several unique functional characteristics. It exhibits low affinity for complement and for most Fc receptors. It furthermore has generally high affinity for its antigen, with binding occurring in a monovalent fashion, as IgG4 can exchange Fab-arms wit...

journal_title：Annals of the New York Academy of Sciences

authors： Huijbers MG,Plomp JJ,van der Maarel SM,Verschuuren JJ

更新日期：2018-02-01 00:00:00

abstract：:The LGR7/RXFP1 and LGR8/RXFP2 receptors are unique receptors among the G-protein-coupled receptors (GPCRs) in having a low-density lipoprotein class A (LDL-A) module. Their complex gene organization, among the intron-richest of the GPCRs, suggests that alternative splicing is a common occurrence. We have therefore inv...

journal_title：Annals of the New York Academy of Sciences

authors： Kern A,Bryant-Greenwood GD

更新日期：2009-04-01 00:00:00

abstract：:Despite intense efforts, little is known about the etiology of prostate cancer, and treatment of advanced forms of the disease has had limited success. Nonetheless, epidemiologic studies combined with animal model and in vitro experiments indicate that natural components of the diet, including n-3 PUFA, the carotenoid...

journal_title：Annals of the New York Academy of Sciences

authors： Cohen LA

更新日期：2002-06-01 00:00:00

abstract：:In two experiments, musically trained and untrained adults were tested on their ability to match spoken utterances with their tonal analogues (tone sequences that retained the pitch and temporal patterns of the utterances). In both cases, musical training was associated with superior performance, indicating an enhance...

journal_title：Annals of the New York Academy of Sciences

authors： Thompson WF,Schellenberg EG,Husain G

更新日期：2003-11-01 00:00:00

abstract：:Activation of cyclic nucleotide-gated (CNG) channels represents the final step in the transduction pathways in both vision and olfaction. Over the past several years, CNG channels have been found in a variety of other cell types where they might fulfill various physiological functions. The olfactory and photoreceptor ...

journal_title：Annals of the New York Academy of Sciences

authors： Broillet MC,Firestein S

更新日期：1999-04-30 00:00:00

abstract：:DNA microarray analysis was conducted to investigate the transcriptional responses of the human monocytic leukemia cell line THP-1 to infection by Chlamydia trachomatis or Coxiella burnetii. RNA was isolated from mock infected cells and cells infected for 36 hours using TRIzol reagent. Biotinylated probes synthesized ...

journal_title：Annals of the New York Academy of Sciences

authors： Ren Q,Robertson SJ,Howe D,Barrows LF,Heinzen RA

更新日期：2003-06-01 00:00:00

abstract：:From the time Dan was 12 years old to the present, he always was the explorer of life. He was very fortunate in having an opportunity to see how life exists in several human societies around the world. His many professional foreign travels are presented. Dan went to a 1959 meeting in Argentina, to England in 1963, and...

journal_title：Annals of the New York Academy of Sciences

authors： Gilbert C,Gilbert RL

更新日期：2000-01-01 00:00:00

abstract：:The lysosomal system has often been considered a prominent morphologic marker of distressed or dying neurons. Lysosomes or their constituent hydrolases have been viewed in different neuropathologic states as either initiators and direct agents of cell death, agents of cellular repair and recompensation, effectors of e...

journal_title：Annals of the New York Academy of Sciences

authors： Nixon RA,Cataldo AM

更新日期：1993-05-28 00:00:00

abstract：:There are multiple connections from the entorhinal cortex (EC) to the hippocampus that carry the information from the EC to the hippocampus. Layer II cells of the medial EC innervating the dentate gyrus (DG)-molecular layer possess K(+)-outward currents and inward rectifier currents that are potentially modulated by c...

journal_title：Annals of the New York Academy of Sciences

authors： Heinemann U,Schmitz D,Eder C,Gloveli T

更新日期：2000-06-01 00:00:00

abstract：:To develop new treatments for beta-thalassemia, it is essential to identify the genes involved in the relevant pathophysiological processes. Iron metabolism in thalassemia mice being investigated, focusing on the expression of a gene called hepcidin (Hamp), which is expressed in the liver and whose product (Hamp) is s...

journal_title：Annals of the New York Academy of Sciences

authors： Breda L,Gardenghi S,Guy E,Rachmilewitz EA,Weizer-Stern O,Adamsky K,Amariglio N,Rechavi G,Giardina PJ,Grady RW,Rivella S

更新日期：2005-01-01 00:00:00

abstract：:Prodigiosin (PG) is an active component of bacterial origin, with reported apoptotic effects. We examined the activation of caspases-9, -8, and -3 in PG-treated Jurkat cells in a dose-response study. These caspases were activated in apoptotic cells, as judged by the appearance of cleavage products from procaspases, an...

journal_title：Annals of the New York Academy of Sciences

authors： Montaner B,Perez-Tomas R

更新日期：2002-11-01 00:00:00

abstract：:Animal trials of many pharmacological neuroprotective agents have been quite successful, whereas trials in humans have been uniformly disappointing. A major difference between laboratory research in animals and clinical research in humans is the amount and/or quality of data obtained. The goal of this presentation is ...

journal_title：Annals of the New York Academy of Sciences

authors： Andrews RJ

更新日期：2005-08-01 00:00:00

abstract：:Justice judgments are subjective by nature, and are influenced substantially by motivational processes. In the present contribution, two motives underlying justice judgments are examined: individualistic motives to evaluate solutions to social problems that benefit the self in material or immaterial ways as fair versu...

journal_title：Annals of the New York Academy of Sciences

authors： van Prooijen JW

更新日期：2013-09-01 00:00:00

abstract：:The general aim of this experiment was to investigate the processes involved in reading musical notation and to study the relationship between written music and its auditory representation. Our main interest was to determine if musicians can develop expectancies for plausible or implausible auditory events on the sole...

journal_title：Annals of the New York Academy of Sciences

authors： Schön D,Besson M

更新日期：2003-11-01 00:00:00

abstract：:The presented paper describes a multi-disciplinary cooling selection approach applied to major gas turbine engine hot section components, including turbine nozzles, blades, discs, combustors and support structures, which maintain blade tip clearances. The paper demonstrates benefits of close interaction between partic...

journal_title：Annals of the New York Academy of Sciences

authors： Glezer B

更新日期：2001-05-01 00:00:00

abstract：:Friendship pervades the human social landscape. These bonds are so important that disrupting them leads to health problems, and difficulties forming or maintaining friendships attend neuropsychiatric disorders like autism and depression. Other animals also have friends, suggesting that friendship is not solely a human...

journal_title：Annals of the New York Academy of Sciences

authors： Brent LJ,Chang SW,Gariépy JF,Platt ML

更新日期：2014-05-01 00:00:00

abstract：:Osteoblast-specific gene transcription requires interaction between bone cell-specific transcription factors and more widely expressed transcriptional regulators. This is particularly evident for the basic domain-leucine zipper factor activating transcription factor 4 (ATF4), whose activity can be enhanced or inhibite...

journal_title：Annals of the New York Academy of Sciences

authors： St-Arnaud R,Hekmatnejad B

更新日期：2011-11-01 00:00:00

abstract：:We study the linear coupling between the Marangoni and Cowley-Rosensweig instabilities for a thin layer of ferrofluid subjected to a temperature gradient and a magnetic field. Both are perpendicular to the reference horizontal boundaries, one of which is a rigid plate, while the other is a free surface remaining flat ...

journal_title：Annals of the New York Academy of Sciences

authors： Hennenberg M,Slavtchev S,Weyssow B

更新日期：2009-04-01 00:00:00

abstract：:The influence of either short-term fasting or vitamin E administration on insulin action was studied in two groups of obese Type 2 diabetic patients. Twelve patients underwent 7 days of fasting (group A), whereas 600 mg of vitamin E was administered daily during 3 months in 9 diabetic patients (group B). Insulin actio...

journal_title：Annals of the New York Academy of Sciences

authors： Skrha J,Sindelka G,Hilgertová J

更新日期：1997-09-20 00:00:00

abstract：:Athletic women are at risk for developing ovulatory dysfunction, which presents variably as menstrual irregularity or absence. Initially characterized as an isolated disruption of hypothalamic gonadotropin-releasing hormone (GnRH) release, athletic amenorrhea, a form of hypogonadotropic hypogonadism, is invariably acc...

journal_title：Annals of the New York Academy of Sciences

authors： Pauli SA,Berga SL

更新日期：2010-09-01 00:00:00

abstract：:This study investigates the effects of agmatine on naloxone-precipitated withdrawal syndrome in morphine-dependent guinea pig ileum. Male guinea pigs that were starved for 24 hours were decapitated after cervical dislocation, and terminal portions of the ilea were removed. Segments were fixed at a resting tension of 1...

journal_title：Annals of the New York Academy of Sciences

authors： Aricioglu F,Ercil E,Dulger G

更新日期：2003-12-01 00:00:00

abstract：:It has previously been shown that stimulation of muscarinic m1 or m3 receptors can, by generating diacylglycerol (DAG) and activating protein kinase C (PKC), accelerate the breakdown of the amyloid precursor protein (APP) to form soluble, non-amyloidogenic peptides (APPs). This relationship has been demonstrated in hu...

journal_title：Annals of the New York Academy of Sciences

authors： Lee RK,Jimenez J,Cox AJ,Wurtman RJ

更新日期：1996-01-17 00:00:00

abstract：:Cell doctrine is the foundational paradigm of Euro-American medicine and biology. Even without stepping outside that tradition, one may imagine alternate models of the body such as a fluid model in which cells do not exist or a model wherein cells are described as overlapping fields of molecular organization in space ...

journal_title：Annals of the New York Academy of Sciences

authors： Theise ND

更新日期：2009-08-01 00:00:00

abstract：:Data Sets used in reverse engineering of biochemical networks contain usually relatively few high-dimensional data points, which makes the problem in general vastly underdetermined. It is therefore important to estimate the probability that a given algorithm will return a model of acceptable quality when run on a data...

journal_title：Annals of the New York Academy of Sciences

authors： Just W

更新日期：2007-12-01 00:00:00

abstract：:Altered metabolism of the Alzheimer's amyloid precursor protein (APP) appears to be a key event in the pathogenesis of Alzheimer's disease (AD), and both altered phosphorylation and oxidative stress appear to affect the production of the toxic Abeta fragment. Our results show that altered processing of APP was observe...

journal_title：Annals of the New York Academy of Sciences

authors： Domingues SC,Henriques AG,Wu W,Da Cruz e Silva EF,Da Cruz e Silva OA

更新日期：2007-01-01 00:00:00

abstract：:Policy and program implementers require evidence on whether integrated psychosocial stimulation and nutrition interventions can be effectively delivered at-scale, how, and at what cost? To address some of these issues, a comprehensive evaluation of implementation was designed for a trial in Pakistan that integrated ps...

journal_title：Annals of the New York Academy of Sciences

authors： Yousafzai AK,Rasheed MA,Siyal S

更新日期：2018-05-01 00:00:00

abstract：:Data on 3080 mother-infant pairs from Cebu in the Philippines were used to conduct a logistics hazards analysis to determine the effect of supplemental calories and the types of supplements that the infant ingests on return to menses. Breast feeding had a significant reduced odds of the mother returning to menses (od...

journal_title：Annals of the New York Academy of Sciences

authors： Zohoori N

更新日期：1994-02-18 00:00:00

abstract：:On the basis of evidence just reviewed, the hormonal requirements during IVM of mammalian oocytes for fertilization and developmental competence may be summarized as follows: 1. Nuclear maturation occurs "spontaneously," without follicular factors or hormones, in all mammalian species. 2. Cumulus cells are necessary d...

journal_title：Annals of the New York Academy of Sciences

authors： Armstrong DT,Zhang X,Vanderhyden BC,Khamsi F

更新日期：1991-01-01 00:00:00