Tracking the elusive lymphocyte: methods of detection during adoptive immunotherapy.

abstract：:There has been a dramatic increase recently in the number of reports of septic episodes associated with both red cell and platelet concentrate transfusions. These reports suggest that transfusion-associated septic reactions may occur as often as 1 per 4000 platelet transfusions, however, the true incidence of the bact...

journal_title：Immunological investigations

authors： Blajchman MA

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Streptococcus pneumoniae is a major pathogen accounting for a large number of pneumococcal disease in worldwide. Due to the mucosal immune pathway induces both systemic and mucosal immune responses, the potential strategy to prevent pneumococcal disease may be to develop a mucosal vaccine. METHOD:In this st...

journal_title：Immunological investigations

authors： Wang D,Lu J,Yu J,Hou H,Leenhouts K,Van Roosmalen ML,Gu T,Jiang C,Kong W,Wu Y

更新日期：2018-05-01 00:00:00

abstract：:Plasmin activity induced by different concentrations of added urokinase (UK) in serum from 20 patients with AIDS (P) and 10 healthy control (HC) subjects was measured using the fibrin plate assay. 125I-fibrin coated 24 well plates were exposed to UK (0.34-6.8 ng/ml) or to trypsin (T) (2.5 micrograms/ml) in the presenc...

journal_title：Immunological investigations

authors： Auci DL,Durkin HG,Murali MR

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Natural killer (NK) cells are the potential modulators of inflammatory reactions that exert several unique biological effects and could lead to future adverse events of coronary artery disease (CAD). HYPOTHESIS:The purpose of this study was to find out the possible association of modulation in NK cell, TNK ...

journal_title：Immunological investigations

authors： Jabir NR,Firoz CK,Ahmed F,Kamal MA,Hindawi S,Damanhouri GA,Almehdar HA,Tabrez S

更新日期：2017-07-01 00:00:00

abstract：:A single-nucleotide polymorphism in the promoter region of the CD14 gene at position 159 has been implicated in susceptibility to infectious diseases. We sought to determine the association between CD14 C-159 T functional promoter polymorphism and brucellosis in Western Iranian population where the disease is endemic....

journal_title：Immunological investigations

authors： Haidari M,Hajilooi M,Rezazadeh M,Rafiei A,Alavi SA,Keramat F

更新日期：2006-01-01 00:00:00

abstract：:The objectives were to determine the prevalence and clinical significance of anti-cyclic citrullinated peptide (anti-CCP) antibodies in patients with juvenile idiopathic arthritis (JIA). Anti-CCP antibodies were checked by ELISA in 68 children with JIA, 38 males and 30 females with mean age of 10.6 (+/-4.02) years and...

journal_title：Immunological investigations

authors： Habib HM,Mosaad YM,Youssef HM

更新日期：2008-01-01 00:00:00

abstract：:The induction of immune tolerance is the most common consequence of protein feeding, i.e., "oral tolerance". In this study we investigated the genetic basis of oral tolerance using various kinds of recombinant and congenic mice, and the cells involved in the development of this phenomenon in mice. The footpad swelling...

journal_title：Immunological investigations

authors： Ishii N,Moriguchi N,Sugita Y,Nakajima H,Tanaka S,Aoki I

更新日期：1993-08-01 00:00:00

abstract：:Cortical (immature) thymocytes are widely reported to express intermediate to high levels of receptors for the lectin, peanut agglutinin (PNA). Light-scatter studies of murine fetal thymocytes stained with PNA or anti-mouse CD4 and CD8 monoclonal antibodies indicated, however, that the most immature CD4-8- (DN) thymoc...

journal_title：Immunological investigations

authors： Holladay S,Blaylock B,Smith B,Luster M

更新日期：1993-12-01 00:00:00

abstract：:It has become apparent that extreme environmental conditions of Antarctic continent alters many immune responses. The present study was conducted on 28th Indian Antarctic expeditioners. The investigations were carried out to explore the effect of multiple stresses like isolation, cold and UV exposure on human immunity...

journal_title：Immunological investigations

authors： Mishra KP,Yadav AP,Shweta,Chanda S,Ganju L,Majumdar D,Ilavazhagan G

更新日期：2010-01-01 00:00:00

abstract：:Background: Immunosuppressive agents are necessary to enhance allograft tolerance after transplantation and the treatment of autoimmune disorders. Regulatory T cells (Tregs) play a pivotal role in improving allograft tolerance and determining the fate of transplanted organs. Therefore, the aim of this study was to inv...

journal_title：Immunological investigations

authors： Keyhanmehr N,Motedayyen H,Eskandari N

更新日期：2019-07-01 00:00:00

abstract：:CD44 comprises a family of type I transmembrane glycoproteins that is expressed on a wide range of cells including those of epithelial, lymphoid and myeloid lineage. Although expression of CD44 in the small intestine is typically localised in the crypts of Lieberkuhn, we have reported the expression of CD44 on mature,...

journal_title：Immunological investigations

authors： Reid SD,Pockley AG

更新日期：2000-08-01 00:00:00

abstract：:White cell infiltration of solid tumors is an important prognostic indicator in malignant disease. Although macrophage infiltration is associated with good outcome in colorectal cancer, a high macrophage content is associated with poor prognosis in breast cancer. Suppressor macrophages prevent T cell activation in nor...

journal_title：Immunological investigations

authors： Toomey D,Harmey J,Condron C,Kay E,Bouchier-Hayes D

更新日期：1999-01-01 00:00:00

abstract：:The critical contribution of CD4+CD25+Foxp3+ T-regulatory cells (Treg) to immune suppression in the tumor microenvironment is well-established. Whereas the mechanisms that drive the generation and accumulation of Treg in tumors have been an active area of study, the information on their origin and population dynamics ...

journal_title：Immunological investigations

authors： Li Q,Egilmez NK

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Rheumatic fever (RF) and its sequel rheumatic heart disease (RHD) is an autoimmune disease caused by an abnormal host immune response to group A streptococcus (GAS) infection. The HLA class II molecules are entailed in immune-mediated infectious, inflammatory, and autoimmune diseases including RHD. However, ...

journal_title：Immunological investigations

authors： Poomarimuthu M,Ramasamy T,Govindan R,Andiappan R,Nagarajan G,Kadiam S,Mariakuttikan J

更新日期：2020-09-23 00:00:00

abstract：:Electroeluted outer membrane proteins [(EOmp), (35-37 KDa, porins)] were highly immunogenic in New Zealand White rabbits. An ELISA peak titer of 51,200 to EOmp as compared to 6,400 for non-eluted outer membrane protein (Omp) was demonstrated. EOmp enhanced the antigenicity of Omp possibly due to epitopes which were ma...

journal_title：Immunological investigations

authors： Kawahara M,Human LG,Kawahara K,Domingue GJ

更新日期：1994-04-01 00:00:00

abstract：:Seven commercially available intravenous immunoglobulins (IVIG) preparations, a gamma globulin prepared by ethanol fractionation, and an experimental IgG isolated by a chromatographic procedure were compared in several tests. Split products were present in preparations manufactured by procedures involving protease tre...

journal_title：Immunological investigations

authors： Medgyesi GA,Kovács J,Füst G,Merétey K

更新日期：1988-04-01 00:00:00

abstract：:For many years, isolation in tissue culture (TC) was considered the test of choice for diagnosis of Chlamydia trachomatis infection. Non-culture tests, such as direct fluorescent antibody (DFA) and enzyme immunoassay (EIA) which detected chlamydial antigens in clinical specimens, made chlamydia diagnostic tests more w...

journal_title：Immunological investigations

authors： Schachter J

更新日期：1997-01-01 00:00:00

abstract：:Anti-α-galactoside antibody (anti-Gal) from human plasma that bound to α-galactoside-bearing guar galactomannan gel and was eluted with specific sugar (affinity-purified anti-Gal ; APAG) invariably contained apo(a) and apo B subunits in a proportion close to that in plasma lipoprotein(a) [Lp(a)]. Since LDL does not co...

journal_title：Immunological investigations

authors： Mandagini G,Subramanian SP,Vasantha K,Appukuttan PS

更新日期：2013-01-01 00:00:00

abstract：:A disintegrin and metalloproteinases (ADAMs) are believed to be involved in the pathogenesis of many fibrosis-related diseases. However, little is known regarding the significance of ADAM17 as a biomarker for interstitial lung disease (ILD). In this study, by using the RT-PCR, western blotting and ELISA, we detected t...

journal_title：Immunological investigations

authors： Ge J,Tang L,Mu P,Zhu F,Xie L,Tang Y

更新日期：2020-02-01 00:00:00

abstract：:Genome-wide association studies have led to the discovery of several susceptibility genes related to autoimmune thyroid diseases (AITDs). However, controversial results have been reported regarding the role of single-nucleotide polymorphism (SNP) of CD40 in the disease susceptibility. The objective of this study was t...

journal_title：Immunological investigations

authors： Wang D,Chen J,Zhang H,Zhang F,Yang L,Mou Y

更新日期：2017-08-01 00:00:00

abstract：:The aim of this study was to evaluate the possible association of IL12B gene polymorphisms with serum levels of IL-12p40, IL-23 and genetic susceptibility to rheumatoid arthritis (RA) in the Bulgarian population. Genotyping for IL12Bpro (rs17860508) and IL12B A/C - 3' UTR (rs3212227) polymorphisms was performed by pol...

journal_title：Immunological investigations

authors： Manolova I,Ivanova M,Vasilev G,Stoilov R,Miteva L,Stanilova S

更新日期：2020-02-01 00:00:00

abstract：:The occurrence of apoptosis in cultured blood cells from HIV+ patients is well-documented. However, the relationship of this process to cytokine production is still undefined. We measured the production of TNF-beta by mitogen-stimulated PBLs from 33 HIV+ patients, while simultaneously assessing their development of ap...

journal_title：Immunological investigations

authors： Lavergne JA,Zorrilla C,del Llano AM

更新日期：1996-07-01 00:00:00

abstract：:Using antigen-induced proliferation assay the presence of macrophages was found to be essential for the development of the T cell response. Decreased ability of antigen presentation by macrophages from aged A/J mice was detected. ...

journal_title：Immunological investigations

authors： Vĕtvicka V,Tlaskalová-Hogenová H,Pospísil M

更新日期：1985-04-01 00:00:00

abstract：:Endomyocardial biopsy is generally used to quantify heart allograft rejection and guide immunotherapy. Biopsy, however, is invasive, costly, and risky. Since rejection requires lymphocyte activation, the purpose of this study was to assess alternative methods to evaluate rejection dynamics by investigating serum level...

journal_title：Immunological investigations

authors： Chang DM,Ding YA,Kuo SY,Chang ML,Wei J

更新日期：1996-01-01 00:00:00

abstract：:Exposure to laboratory animals poses a hazard for development of occupational allergy. Identification of antigenic determinants of allergenic proteins may be valuable for immunotherapeutic purposes. Overlapping peptides of the major allergen in rat urine, Rat n 1.02, corresponding to the protein alpha2u-globulin were ...

journal_title：Immunological investigations

authors： Bayard C,Siddique AB,Berzins K,Troye-Blomberg M,Hellman U,Vesterberg O

更新日期：1999-09-01 00:00:00

abstract：:Antigen (HSA) bound in immune complexes at equivalence with syngeneic anti-HSA antibodies elicit much stronger humoral immune response then soluble HSA. On the other hand, administration of immune complexes formed with xenogeneic (rabbit) anti-HSA antibodies suppressed humoral immune response against HSA, but not agai...

journal_title：Immunological investigations

authors： Marusić M,Marusić-Galesić S,Pokrić B

更新日期：1992-12-01 00:00:00

abstract：:DNA vaccine represents a powerful approach for prevention of avian H5N1 influenza infection. Yet, DNA vaccine-induced immune responses might be limited by the short duration of antigen expression. As a strategy to enhance adaptive immune responses elicited by a hemagglutinin 5 (H5) DNA vaccine, we explored the effect ...

journal_title：Immunological investigations

authors： Tabatabaeizadeh SE,Bassami MR,Haghparast A,Dehghani H

更新日期：2015-01-01 00:00:00

abstract：:Rapid and accurate diagnosis of cytomegalovirus (CMV) infection is imperative with the advent of effective antiviral therapy (gangiclovir, foscarnet, CMV hyperimmune globin). Applications of conventional cell culture (CC), shell vial assay (SV), serological testing, antigenemia assay (AG) as well as molecular methods ...

journal_title：Immunological investigations

authors： Myers JB,Amsterdam D

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Infections are usually involved in the pathogenesis of spondyloarthritis (SpA). Mannose-binding lectin (MBL) is a component of the innate immune system with an important role in microbial defense. OBJECTIVE:To study the prevalence of MBL deficiency in SpA patients as well as its influence in the clinical pr...

journal_title：Immunological investigations

authors： Skare TL,Nisihara R,Cieslinski JZ,Zeni JO,Rasera HN,Messias-Reason I,Utiyama SR

更新日期：2017-02-01 00:00:00

abstract：:Studies presented examine the origin of IgA plasma cells in B lineage chimeric mice constructed by reconstituting lethally irradiated mice with a mixture of syngeneic bone marrow cells and peritoneal cells from Ig heavy chain allotype congenic donors. In these mice, essentially all B cells in spleen and Peyer's patche...

journal_title：Immunological investigations

authors： Kroese FG,Butcher EC,Stall AM,Herzenberg LA

更新日期：1989-01-01 00:00:00