Growth regulation of the interstitial cell population in hydra. I. Evidence for global control by nerve cells in the head.

abstract：:We have isolated a cDNA of the DEAD protein family from a Xenopus ovary cDNA library. Northern hybridization revealed that the mRNA corresponding to the cDNA [XVLG1 (Xenopus vasa-like gene)] was specifically expressed in adult testis and ovary. The deduced amino acid sequence of XVLG1 was relatively homologous to that...

journal_title：Developmental biology

authors： Komiya T,Itoh K,Ikenishi K,Furusawa M

更新日期：1994-04-01 00:00:00

abstract：:Interleukin-6 is a member of a class of hormone-like molecules termed cytokines. The actions of IL-6 are highly pleiotropic. In adults IL-6 functions as a major mediator of inflammatory responses as well as inducing the synthesis of acute phase proteins by the liver following infection or injury. Based on in vitro and...

journal_title：Developmental biology

authors： Lee FD

更新日期：1992-06-01 00:00:00

abstract：:Much of boundary formation during development remains to be understood, despite being a defining feature of many animal taxa. Axial patterning of Hydra, a member of the ancient phylum Cnidaria which diverged prior to the bilaterian radiation, involves a steady-state of production and loss of tissue, and is dependent o...

journal_title：Developmental biology

authors： López-Quintero JA,Torres GG,Neme R,Bosch TCG

更新日期：2020-02-15 00:00:00

abstract：:The canonical, beta-catenin-dependent Wnt pathway is a crucial player in the early events of Xenopus development. Dorsal axis formation and mesoderm patterning are accepted effects of this pathway, but the regulation of expression of genes involved in mesoderm specification is not. This conclusion is based largely on ...

journal_title：Developmental biology

authors： Vonica A,Gumbiner BM

更新日期：2002-10-01 00:00:00

abstract：:The Drosophila ovarian germline stem cells (GSCs) constantly experience self-renewal and differentiation, ensuring the female fertility throughout life. The balance between GSC self-renewal and differentiation is exquisitely regulated by the stem cell niche, the stem cells themselves and systemic factors. Increasing e...

journal_title：Developmental biology

authors： Xuan T,Xin T,He J,Tan J,Gao Y,Feng S,He L,Zhao G,Li M

更新日期：2013-07-15 00:00:00

abstract：:Using gene-specific probes derived from four mouse gamma-crystallin cDNAs, we have examined the regulation of different members of the mouse gamma-crystallin gene family during lens development. Our analysis revealed that, while the different gamma-crystallin genes appear to be coordinately activated during embryogene...

journal_title：Developmental biology

authors： Murer-Orlando M,Paterson RC,Lok S,Tsui LC,Breitman ML

更新日期：1987-01-01 00:00:00

abstract：:C. elegans ahr-1 is orthologous to the mammalian aryl hydrocarbon receptor, and it functions as a transcription factor to regulate the development of certain neurons. Here, we describe the role of ahr-1 in a specific behavior: the aggregation of C. elegans on lawns of bacterial food. This behavior is modulated by nutr...

journal_title：Developmental biology

authors： Qin H,Zhai Z,Powell-Coffman JA

更新日期：2006-10-15 00:00:00

abstract：:Progression of germ cells through meiosis is regulated by phosphorylation events. We previously showed the key role of cyclin dependent kinases in meiotic divisions of rat spermatocytes co-cultured with Sertoli cells (SC). In the present study, we used the same culture system to address the role of mitogen-activated p...

journal_title：Developmental biology

authors： Godet M,Sabido O,Gilleron J,Durand P

更新日期：2008-03-01 00:00:00

abstract：:The dorsal air sacs supply oxygen to the flight muscles of the Drosophila adult. This tracheal organ grows from an epithelial tube (the air sac primordium (ASP)) that arises during the third larval instar (L3) from a wing-disc-associated tracheal branch. Since the ASP is generated by a program of both morphogenesis an...

journal_title：Developmental biology

authors： Guha A,Kornberg TB

更新日期：2005-11-01 00:00:00

abstract：:Cell surface and cytoplasmic polarity is exhibited by the blastomeres of mouse preimplantation embryos following compaction at the 8-cell stage of cleavage. It has been hypothesized that cytoplasmic polarity is initiated by plasma membrane functions of polar blastomeres that are absent from apolar blastomeres. To test...

journal_title：Developmental biology

authors： Wiley LM,Obasaju MF

更新日期：1988-11-01 00:00:00

abstract：:For both the intricate morphogenetic layout of the sensory cells in the ear and the elegantly radial arrangement of the sensory neurons in the nose, numerous signaling molecules and genetic determinants are required in concert to generate these specialized neuronal populations that help connect us to our environment. ...

journal_title：Developmental biology

authors： Maier EC,Saxena A,Alsina B,Bronner ME,Whitfield TT

更新日期：2014-05-01 00:00:00

abstract：:The genetic and developmental bases for trait expression and variation in adults are largely unknown. One system in which genes and cell behaviors underlying adult traits can be elucidated is the larval-to-adult transformation of zebrafish, Danio rerio. Metamorphosis in this and many other teleost fishes resembles amp...

journal_title：Developmental biology

authors： Parichy DM,Turner JM

更新日期：2003-04-15 00:00:00

abstract：:The zebrafish hedgehog (hh) family members tiggy-winkle hedgehog (twhh) and sonic hedgehog (shh) are involved in patterning the ventral CNS and proximal eye. Using a dominant negative protein kinase A regulatory subunit mutant, we show that these hh activities are mediated by protein kinase A. The effects of dominant ...

journal_title：Developmental biology

authors： Ungar AR,Moon RT

更新日期：1996-08-25 00:00:00

abstract：:Retinoic acid (RA) is a potent inducer of cell differentiation and plays an essential role in sex-specific germ cell development in the mammalian gonad. RA is essential for male gametogenesis and hence fertility. However, RA can also disrupt sexual cell fate in somatic cells of the testis, promoting transdifferentiati...

journal_title：Developmental biology

authors： Minkina A,Lindeman RE,Gearhart MD,Chassot AA,Chaboissier MC,Ghyselinck NB,Bardwell VJ,Zarkower D

更新日期：2017-04-15 00:00:00

abstract：:Sequence analysis of cDNA clones encoding fibronectin (FN) from Xenopus laevis reveals extensive amino acid identities with other vertebrate FNs, including the presence of the Arg-Gly-Asp (RGD) cell attachment site in type III-10 and of a second, cell-binding site (EILDV) in the alternative spliced V region of the pro...

journal_title：Developmental biology

authors： DeSimone DW,Norton PA,Hynes RO

更新日期：1992-02-01 00:00:00

abstract：:The myelin of the peripheral nervous system from the shiverer mutant mice is characterized by the absence of myelin basic protein, while the other myelin protein components are present at normal levels. Myelin lamella formation is normal in the shiverer mutant. Therefore, by using antiserum against myelin basic protei...

journal_title：Developmental biology

authors： Mikoshiba K,Yokoyama M,Takamatsu K,Tsukada Y,Nomura T

更新日期：1984-09-01 00:00:00

abstract：:An abundant phosphoprotein with an apparent molecular mass of 65 kDa (p65) has been identified that is enriched in developing new macronuclei (or anlagen) isolated from the holotrichous ciliate, Tetrahymena thermophila. During early stages of macronuclear development, p65 is actively synthesized and deposited into you...

journal_title：Developmental biology

authors： Madireddi MT,Davis MC,Allis CD

更新日期：1994-10-01 00:00:00

abstract：:During limb development, Sonic hedgehog (SHH) and HOX proteins are considered among the most important factors regulating digit number and identity. SHH signaling prevents the processing of GLI3 into a short form that functions as a strong transcriptional repressor. Gli3 mutant limbs are characterized by a severe poly...

journal_title：Developmental biology

authors： Sheth R,Bastida MF,Ros M

更新日期：2007-10-15 00:00:00

abstract：:We have used in situ hybridization and RNA blotting analysis to compare the timing of accumulation of poly(A) and alpha-subtype histone mRNA during oogenesis in the sea urchin Strongylocentrotus purpuratus. In situ hybridization with 3H-poly(U) shows that the content of poly(A) in the developing oocyte increases four-...

journal_title：Developmental biology

authors： Angerer LM,DeLeon DV,Angerer RC,Showman RM,Wells DE,RafF RA

更新日期：1984-02-01 00:00:00

abstract：:Morphogenesis of the cartilaginous otic capsule is directed by interactions between the epithelial anlage of the membranous labyrinth (otocyst) and its associated periotic mesenchyme. Utilizing a developmental series of high-density (micromass) cultures of periotic mesenchyme to model capsule chondrogenesis, we have s...

journal_title：Developmental biology

authors： Frenz DA,Van De Water TR

更新日期：1991-03-01 00:00:00

abstract：:Two main processes are involved in driving ventral mesendoderm internalization in the Xenopus gastrula. First, vegetal rotation, an active movement of the vegetal cell mass, initiates gastrulation by rolling the peripheral blastocoel floor against the blastocoel roof. In this way, the leading edge of the internalized ...

journal_title：Developmental biology

authors： Ibrahim H,Winklbauer R

更新日期：2001-12-01 00:00:00

abstract：:The large ampullate glands of the orb-web spider, Nephila clavipes provide massive amounts of fibroin throughout the lifetime of the adult female. We have developed methods to culture the glands and manipulate their biosynthetic activity. This has allowed us to monitor a series of molecular events that precede silk pr...

journal_title：Developmental biology

authors： Candelas GC,Arroyo G,Carrasco C,Dompenciel R

更新日期：1990-07-01 00:00:00

abstract：:Little is known about the genetic basis of behavioral choice, such as temperature preference, especially in natural populations. Thermal preference can play a key role in habitat selection, for example in aquatic species. Examining this behavior on a genetic level requires access to individuals or populations of the s...

journal_title：Developmental biology

authors： Tabin JA,Aspiras A,Martineau B,Riddle M,Kowalko J,Borowsky R,Rohner N,Tabin CJ

更新日期：2018-09-15 00:00:00

abstract：:The lizards are evolutionarily the closest vertebrates to humans that demonstrate the ability to regenerate entire appendages containing cartilage, muscle, skin, and nervous tissue. We previously isolated PAX7-positive cells from muscle of the green anole lizard, Anolis carolinensis, that can differentiate into multin...

journal_title：Developmental biology

authors： Palade J,Djordjevic D,Hutchins ED,George RM,Cornelius JA,Rawls A,Ho JWK,Kusumi K,Wilson-Rawls J

更新日期：2018-01-15 00:00:00

abstract：:The ubiquitin-proteasome system is essential for intracellular protein degradation, but there are few studies of this system in the extracellular milieu. Recently, we reported that a 70-kDa sperm receptor, HrVC70, on the vitelline coat is ubiquitinated and then degraded by the sperm proteasome during fertilization of ...

journal_title：Developmental biology

authors： Sakai N,Sawada H,Yokosawa H

更新日期：2003-12-01 00:00:00

abstract：:We previously isolated a p53 cDNA from a Xenopus oocyte library. To determine if p53 has a function in the developmental period, we have studied its expression at the RNA and protein levels during the early development of Xenopus laevis. Two p53 transcripts (3 and 2.2 kb) are expressed from the beginning of Xenopus oo...

journal_title：Developmental biology

authors： Tchang F,Gusse M,Soussi T,Méchali M

更新日期：1993-09-01 00:00:00

abstract：:The subventricular zone (SVZ) of the developing mammalian forebrain gives rise to astrocytes and oligodendrocytes in the neocortex and white matter, and neurons in the olfactory bulb in perinatal life. We have examined the developmental fates and spatial distributions of the descendants of single SVZ cells by infectin...

journal_title：Developmental biology

authors： Zerlin M,Milosevic A,Goldman JE

更新日期：2004-06-01 00:00:00

abstract：:The Notch signaling pathway controls cell fate choices at multiple steps during cell lineage progression. To produce the cell fate choice appropriate for a particular stage in the cell lineage, Notch signaling needs to interpret the cell context information for each stage and convert it into the appropriate cell fate ...

journal_title：Developmental biology

authors： Das D,Lanner F,Main H,Andersson ER,Bergmann O,Sahlgren C,Heldring N,Hermanson O,Hansson EM,Lendahl U

更新日期：2010-12-15 00:00:00

abstract：:The Xenopus helix-loop-helix transcription factor Hairy2 is essential for neural crest progenitor survival and maintains cells in a mitotic undifferentiated pre-neural crest state. However, its mode of action remains largely unknown. Here we show that a Hairy2 DNA-binding mutant is unable to promote cell survival and ...

journal_title：Developmental biology

authors： Nichane M,Ren X,Souopgui J,Bellefroid EJ

更新日期：2008-10-15 00:00:00

abstract：:Zygotes and embryos of the fucoid brown alga Pelvetia compressa undergo a series of asymmetric cleavages. We are interested in the developmental role of these cleavages and the mechanism controlling their alignment. To assess the importance of division plane alignment, the orientation of the first asymmetric division ...

journal_title：Developmental biology

authors： Bisgrove SR,Kropf DL

更新日期：1998-02-15 00:00:00