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Interactions between hepatotropic viruses in patients with haemophilia.

Abstract：

:Infections with the hepatotropic viruses non-A, non-B (NANB), hepatitis B (HBV) and delta agent (HDV) are described in two patients with haemophilia. The first patient illustrates the phenomenon of interference following a simultaneous exposure to NANB and HBV. The second patient, a carrier of hepatitis B surface antigen (HBsAg), acquired superinfection with HDV which resulted in acute hepatitis progressing to chronic hepatitis. Liver disease seen in multitransfused haemophiliacs may be significantly different to that seen in other patients. As a consequence of the infusion of blood clotting factor concentrates, these patients become the site of complex viral interactions.

journal_name

J Hepatol

journal_title

Journal of hepatology

authors

Lee CA,Kernoff PB,Karayiannis P,Farci P,Thomas HC

doi

10.1016/s0168-8278(85)80775-3

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

379-84

issue

4

eissn

0168-8278

issn

1600-0641

pii

S0168-8278(85)80775-3

journal_volume

1

pub_type

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