Juvenile xanthogranuloma. Clinicopathologic analysis and immunohistochemical study of 57 patients.

Abstract:

:Fifty-seven cases of juvenile xanthogranuloma that fulfilled the classic description of histologic findings of the disease were analyzed clinicopathologically and immunohistochemically. Two forms could be distinguished: 47 cases of the infantile form and 10 of the adolescent and young adult form. The infantile lesion was found at birth in 8 patients (17%), and was noted within 1 year after birth in 33 (70%). Twenty-two had multiple lesions and five of the six for whom follow-up was feasible had spontaneous involution. About half of the lesions were located on the head and neck, 30% on the trunk, and 20% on the extremities. All six adolescents had a solitary tumor located in the head and neck region. Comparison of the latter form with reticulohistiocytoma and cutaneous fibrous histiocytoma was established from a differential point of view. Immunohistochemically, most lesions of juvenile xanthogranuloma displayed a positive reaction for lysozyme and alpha-1-antichymotrypsin and were negative for S-100 protein, thereby suggesting that the essential constituents of this lesion would derive from the mononuclear phagocyte system.

journal_name

Cancer

journal_title

Cancer

authors

Sonoda T,Hashimoto H,Enjoji M

doi

10.1002/1097-0142(19851101)56:9<2280::aid-cncr2820

subject

Has Abstract

pub_date

1985-11-01 00:00:00

pages

2280-6

issue

9

eissn

0008-543X

issn

1097-0142

journal_volume

56

pub_type

杂志文章

相关文献

CANCER文献大全
  • Cisplatin and 5-fluorouracil for advanced locoregional and metastatic squamous cell carcinoma of the skin.

    abstract::Seven patients with advanced locoregional or metastatic squamous cell carcinoma of the skin were treated with cis-daimminedichloroplatin (cisplatin) and 5-fluorouracil (5-FU). Responses were seen in six of seven patients (three partial responses [PR] and three complete responses [CR]). One patient is alive and disease...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(19910415)67:8<2030::aid-cncr2820

    authors: Khansur T,Kennedy A

    更新日期:1991-04-15 00:00:00

  • Malignant thymoma with peripheral blood lymphocytosis.

    abstract::A 37-year-old woman with a giant, lymphocytic predominant thymoma involving the pleura and accompanied by a sharp peripheral blood lymphocytosis is described. Only electromicroscopic and immunohistologic studies could exclude the alternative diagnosis of mediastinal lymphoma. The tumor and peripheral blood lymphocytes...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19880315)61:6<1222::aid-cncr2820

    authors: Shachor Y,Radnay J,Bernheim J,Rozenszajn A,Bruderman I,Klajman A,Steiner ZP

    更新日期:1988-03-15 00:00:00

  • Women age < or = 35 years with primary breast carcinoma: disease features at presentation.

    abstract:BACKGROUND:The purpose of the current study was to describe a population of young patients with breast carcinoma, their characteristics at the time of diagnosis, and the association of these characteristics with disease recurrence and survival. METHODS:Four hundred fifty-two women age < or = 35 years with breast carci...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21070

    authors: Gonzalez-Angulo AM,Broglio K,Kau SW,Eralp Y,Erlichman J,Valero V,Theriault R,Booser D,Buzdar AU,Hortobagyi GN,Arun B

    更新日期:2005-06-15 00:00:00

  • Improved survival of patients with melanoma with an antibody response to immunization to a polyvalent melanoma vaccine.

    abstract:BACKGROUND:Melanoma vaccine treatment appears to slow the progression of melanoma in some patients, particularly in patients in whom it stimulates cellular antimelanoma immune responses. The relationship of vaccine-induced antibody responses to clinical outcome is less clear. The purpose of this study was to investigat...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19950115)75:2<495::aid-cncr28207

    authors: Miller K,Abeles G,Oratz R,Zeleniuch-Jacquotte A,Cui J,Roses DF,Harris MN,Bystryn JC

    更新日期:1995-01-15 00:00:00

  • Effects of melatonin on physical fatigue and other symptoms in patients with advanced cancer receiving palliative care: A double-blind placebo-controlled crossover trial.

    abstract:BACKGROUND:Patients with advanced cancer often experience fatigue and other symptoms that negatively impact their quality of life. The current trial investigated the effect of melatonin on fatigue and other symptoms in patients with advanced cancer. METHODS:Patients who were aged ≥18 years, had a histologically confir...

    journal_title:Cancer

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/cncr.29563

    authors: Lund Rasmussen C,Klee Olsen M,Thit Johnsen A,Petersen MA,Lindholm H,Andersen L,Villadsen B,Groenvold M,Pedersen L

    更新日期:2015-10-15 00:00:00

  • Management of asparaginase induced hemorrhagic pancreatitis complicated by pseudocyst.

    abstract::Asparaginase induced hemorrhagic pancreatitis is a rare but serious development occurring in less than 0.5% of patients treated with this drug. Severe pancreatitis with progressive abdominal distention, toxemia, hypotension and respiratory insufficiency occurred in an 18-year-old patient with acute lymphoblastic leuke...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197902)43:2<718::aid-cncr2820430

    authors: Greenstein R,Nogeire C,Ohnuma T,Greenstein A

    更新日期:1979-02-01 00:00:00

  • Molecular predictors of outcome in a phase 3 study of gemcitabine and erlotinib therapy in patients with advanced pancreatic cancer: National Cancer Institute of Canada Clinical Trials Group Study PA.3.

    abstract:BACKGROUND:National Cancer Institute of Canada Clinical Trials Group PA.3 (NCIC CTG PA.3) was a phase 3 study (n = 569) that demonstrated benefits for overall survival and progression-free survival with the addition of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) erlotinib to gemcitabine ...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1002/cncr.25393

    authors: da Cunha Santos G,Dhani N,Tu D,Chin K,Ludkovski O,Kamel-Reid S,Squire J,Parulekar W,Moore MJ,Tsao MS

    更新日期:2010-12-15 00:00:00

  • Epidemiologic and histologic patterns of Hodgkin's disease in blacks.

    abstract::The epidemiologic pattern for Hodgkin's disease in blacks from two different communities in the United States was characterized by higher childhood rates and significantly lower rates in the young adult and older age groups than for whites. In addition, a significantly greater number of black patients belonged to low ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197712)40:6<3133::aid-cncr282040

    authors: Vianna NJ,Thind IS,Louria DB,Polan A,Kirmss V,Davies JN

    更新日期:1977-12-01 00:00:00

  • The role of postoperative chemoradiation for oropharynx carcinoma: a critical appraisal of the published literature and National Comprehensive Cancer Network guidelines.

    abstract::The National Comprehensive Cancer Network (NCCN) describes the presence of extracapsular spread and/or positive margins in oropharynx cancer (OPC) as an indication for the addition of chemotherapy to postoperative radiation. The guideline's category 1 consensus is based on what they term high-level evidence. For this ...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.29242

    authors: Sinha P,Piccirillo JF,Kallogjeri D,Spitznagel EL,Haughey BH

    更新日期:2015-06-01 00:00:00

  • Thermography. Its relation to pathologic characteristics, vascularity, proliferation rate, and survival of patients with invasive ductal carcinoma of the breast.

    abstract:BACKGROUND:The reason for the thermal abnormality associated with some breast cancers is unclear. We previously reported that a thermographic abnormality is associated with tumor size and lymph node involvement. Despite this association, we were unable to demonstrate an independent association between an abnormal therm...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0142(19960401)77:7<1324::AID-CN

    authors: Sterns EE,Zee B,SenGupta S,Saunders FW

    更新日期:1996-04-01 00:00:00

  • Factors predicting long-term survival for metastatic breast cancer patients treated with high-dose chemotherapy and bone marrow support.

    abstract:BACKGROUND:Poor prognosis of Stage IV breast cancer patients have at best a 10% 3-year survival rate with conventional chemotherapy. Dose-intensive chemotherapy improved survival rates for some of these patients. METHODS:All patients were Stage IV estrogen receptor-negative or estrogen receptor-positive hormonal refra...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/1097-0142(19940415)73:8<2157::aid-cncr2820

    authors: Dunphy FR,Spitzer G,Fornoff JE,Yau JC,Huan SD,Dicke KA,Buzdar AU,Hortobagyi GN

    更新日期:1994-04-15 00:00:00

  • The occurrence of soft tissue sarcomas in three siblings with Werner's syndrome.

    abstract::Werner's syndrome, a relatively rare and autosomal recessive disorder, is well known to be characterized by a high frequency of malignant neoplasm. The occurrence of familial neoplasm in patients with this condition, however, has been recorded only once before in the literature. Reported are the findings with regard t...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19841201)54:11<2580::aid-cncr282

    authors: Usui M,Ishii S,Yamawaki S,Hirayama T

    更新日期:1984-12-01 00:00:00

  • The treatment of childhood acute lymphoblastic leukemia in Guatemala: Biologic features, treatment hurdles, and results.

    abstract:BACKGROUND:The National Pediatric Oncology Unit (UNOP) is the only pediatric hemato-oncology center in Guatemala. METHODS:Patients ages 1 to 17 years with acute lymphoblastic leukemia (ALL) were treated according to modified ALL Intercontinental Berlin-Frankfurt-Münster (IC-BFM) 2002 protocol. Risk classification was ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.30257

    authors: Antillón FG,Blanco JG,Valverde PD,Castellanos M,Garrido CP,Girón V,Letona TR,Osorio EJ,Borrayo DA,Mack RA,Melgar MA,Lorenzana R,Ribeiro RC,Metzger M,Conter V,Rossi E,Valsecchi MG

    更新日期:2017-02-01 00:00:00

  • Primary malignant lymphoma of the breast. Lymphoma of the mucosa-associated lymphoid tissue.

    abstract::Eight cases of primary non-Hodgkin's lymphoma of the breast found in the pathology files of the Institute of Oncology, Ljubljana, Yugoslavia, for a period of 25 years (from 1961 to 1985) were analyzed. During the same period 5711 cases of breast carcinoma were seen. Seven cases were diffuse lymphomas, and one case was...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19871215)60:12<3033::aid-cncr282

    authors: Lamovec J,Jancar J

    更新日期:1987-12-15 00:00:00

  • Sites of primary malignancies in patients presenting with cerebral metastases. A review of 120 cases.

    abstract::A retrospective study is reported of 120 consecutive cases of patients presenting with brain metastases as the primary sign of their malignancy. Primary site was found in 62 patients (53 while alive and 9 at postmortem examination) and remained unknown in 58. Lung was the most frequent primary site (45% of known sites...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19850815)56:4<880::aid-cncr28205

    authors: Le Chevalier T,Smith FP,Caille P,Constans JP,Rouesse JG

    更新日期:1985-08-15 00:00:00

  • Radition therpay control of nine patients with malignant thymoma.

    abstract::Malignant thymoma is a relatively rare condition and a review of the literature reveals approximately 100 reported cases. Only a small percentage of these have been treated with megavoltage radiation therapy; therefore, it is difficult to find the necessary information to establish a proper time-dose relationship for ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197801)41:1<117::aid-cncr2820410

    authors: Marks RD Jr,Wallace KM,Pettit HS

    更新日期:1978-01-01 00:00:00

  • A Phase II clinical trial of idarubicin administered to children with relapsed brain tumors.

    abstract:BACKGROUND:Idarubicin (IDR), an anthracycline that is a derivative of daunorubicin, was synthesized in an attempt to find new analogs of daunorubicin with an improved spectrum of activity and diminished acute or chronic toxicity. Because of the favorable pharmacokinetic profile of IDR (with the persistence of its activ...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1002/(sici)1097-0142(19980815)83:4<813::aid-cnc

    authors: Arndt CA,Krailo MD,Steinherz L,Scheithauer B,Liu-Mares W,Reaman GH

    更新日期:1998-08-15 00:00:00

  • Recombinant interleukin-2 activates peripheral blood lymphocytes from children with acute leukemia to kill autologous leukemic cells.

    abstract::In order to determine if recombinant interleukin-2 (rIL-2) can induce lymphokine-activated killer (LAK) cells able to lyse autologous leukemic cells, we incubated peripheral blood (PB) mononuclear cells from children with acute leukemia with 50 U/ml rIL-2 for 5 days. These PB effector cells were then tested for their ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19881101)62:9<1928::aid-cncr2820

    authors: Findley HW Jr,Abdel Mageed A,Nasr SA,Ragab AH

    更新日期:1988-11-01 00:00:00

  • A pilot study of interleukin-2 for adult patients with acute myelogenous leukemia in first complete remission.

    abstract:BACKGROUND:Interleukin-2 (IL-2) has immunomodulatory effects, including stimulating the activity of cytotoxic T cells and natural killer cells, and inducing the generation of lymphokine-activated killer cells. The authors investigated whether IL-2 may improve the duration of complete remission (CR) and survival in acut...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,评审

    doi:

    authors: Cortes JE,Kantarjian HM,O'Brien S,Giles F,Keating MJ,Freireich EJ,Estey EH

    更新日期:1999-04-01 00:00:00

  • Gemcitabine-based doublets versus single-agent therapy for elderly patients with advanced nonsmall cell lung cancer: a Literature-based Meta-analysis.

    abstract:BACKGROUND:: Although platinum-based combinations are considered the best option of care for patients with advanced nonsmall cell lung cancer (NSCLC), single-agent therapy is the preferred treatment for older patients. Since the late 1990s, various combinations of third-generation agents (gemcitabine [G], vinorelbine, ...

    journal_title:Cancer

    pub_type: 杂志文章,meta分析

    doi:10.1002/cncr.24207

    authors: Russo A,Rizzo S,Fulfaro F,Adamo V,Santini D,Vincenzi B,Gebbia N,Carreca I

    更新日期:2009-05-01 00:00:00

  • Histogenesis of spontaneous regression of cervical intraepithelial neoplasias.

    abstract::It is justifiable to assume that a spontaneous regression of cervical intraepithelial neoplasia is in progress when pathologic epithelium is replaced by normal epithelium. Very rare histologic pictures of this process are shown. Dysplastic squamous epithelium or intraepithelial carcinomas become detached from their ba...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(1984)54:4<616::aid-cncr282054040

    authors: Bajardi F

    更新日期:1984-08-15 00:00:00

  • Phase I study of escalating doses of mitoxantrone and paclitaxel with granulocyte-macrophage colony stimulating factor support.

    abstract:BACKGROUND:Both paclitaxel and mitoxantrone demonstrate significant antineoplastic activity in breast cancer patients. Colony stimulating factor support allows significant dose escalation of each of these drugs when administered as a single agent. METHODS:We performed a Phase I study employing escalating doses of pacl...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/(SICI)1097-0142(19960601)77:11<2308::AID-C

    authors: Fleming GF,Janisch L,Vogelzang NJ,Vokes EE,Ratain MJ

    更新日期:1996-06-01 00:00:00

  • Malignant metastatic disease of the eye: management of an uncommon complication.

    abstract::Twenty-four patients with metastatic cancer of the choroid were seen in the Department of Therapeutic Radiology, Rush-Presbyterian--St. Luke's Medical Center, Chicago, between 1964 and 1975. One fourth of the patients had involvement in both eyes, for a total of 30 eyes involved with metastatic cancer. The most common...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Reddy S,Saxena VS,Hendrickson F,Deutsch W

    更新日期:1981-02-15 00:00:00

  • Preleukemic changes in cases of nonlymphocytic leukemia secondary to cytotoxic therapy. Analysis of 105 cases.

    abstract::Peripheral blood changes preceding therapy-related leukemia were studied in 105 patients who had received cytotoxic therapy, 53 for Hodgkin's disease and 52 for other cancers. Preleukemic anomalies were observed in 74.3% of the cases, appearing after a mean interval of 68.7 months after diagnosis of the initial cancer...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19860801)58:3<630::aid-cncr28205

    authors: De Gramont A,Louvet C,Krulik M,Smadja N,Donadio D,Laporte JP,Brissaud P,Smith M,Delâge JM,Drolet Y

    更新日期:1986-08-01 00:00:00

  • Primary malignant fibrous histiocytoma of the aorta.

    abstract::A rare case of malignant fibrous histiocytoma of the aorta is reported. Review of the literature revealed that primary tumors of the aorta are exclusively mesenchymal tumors that almost invariably pursue a fatal course. ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810801)48:3<840::aid-cncr28204

    authors: Chen KT

    更新日期:1981-08-01 00:00:00

  • Multimodality therapy for patients with clinical Stage I and II malignant mixed Müllerian tumors of the uterus.

    abstract:BACKGROUND:The role of adjuvant therapy in the management of patients with malignant mixed Müllerian tumors (MMMT) of the uterus has not been defined. The outcome of planned multimodality therapy for patients with apparent early stage disease was assessed. METHODS:A pilot study was performed on 38 patients with clinic...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:

    authors: Manolitsas TP,Wain GV,Williams KE,Freidlander M,Hacker NF

    更新日期:2001-04-15 00:00:00

  • Adjuvant immunotherapy and chemoimmunotherapy in colorectal cancer (Dukes' class C): prolongation of disease-free interval and survival.

    abstract::The poor postsurgical prognosis in patients with colorectal cancer of the Dukes' C classification has prompted a clinical trial of adjuvant immunotherapy versus chemoimmunotherapy intended to prolong either the disease-free interval or the overall survival or both. One hundred and twenty-one patients have been entered...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197711)40:5+<2726::aid-cncr28204

    authors: Mavligit GM,Gutterman JU,Malahy MA,Burgess MA,McBride CM,Jubert A,Hersh EM

    更新日期:1977-11-01 00:00:00

  • A functioning catecholamine-secreting vagal body tumor. A case report and review of the literature.

    abstract::There are few cases of catecholamine-secreting paragangliomas of the neck reported in the literature, most of these being of the carotid body and glomus-jugulare type. This report cites the second case of a functioning vagal body tumor secreting norepinephrine predominantly and producing labile hypertension and sympto...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19830901)52:5<932::aid-cncr28205

    authors: Tannir NM,Cortas N,Allam C

    更新日期:1983-09-01 00:00:00

  • A new effective four-drug combination of CCNU (1-[2-chloroethyl]-3-cyclohexyl-1-nitrosourea) (NSC-79038), vinblastine, prednisone, and procarbazine for the treatment of advanced Hodgkin's disease.

    abstract::Five hundred and sixty-six patients with either Stage III or IV Hodgkin's disease were prospectively randomized to test whether CCNU and/or vinblastine are more effective than mechlorethamine and/or vincristine with procarbazine and prednisone. The combination of CCNU, vinblastine, procarbazine, and prednisone (CVPP) ...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/1097-0142(19800815)46:4<654::aid-cncr28204

    authors: Cooper MR,Pajak TF,Nissen NI,Stutzman L,Brunner K,Cuttner J,Falkson G,Grunwald H,Bank A,Leone L,Seligman BR,Silver RT,Weiss RB,Haurani F,Blom J,Spurr CL,Glidewell OJ,Gottlieb AJ,Holland JF

    更新日期:1980-08-15 00:00:00

  • Pattern of disease recurrence and prognostic factors in patients with osteosarcoma treated with contemporary chemotherapy.

    abstract:BACKGROUND:The goal of the current study was to define the clinical features and outcome of recurrent osteosarcoma (OS) in children and young adults initially treated with contemporary chemotherapy. METHODS:The authors reviewed the clinical features, therapy, and outcome for 59 patients from the Mayo Clinic (Rochester...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11799

    authors: Hawkins DS,Arndt CA

    更新日期:2003-12-01 00:00:00