Abstract:
:Asparaginase induced hemorrhagic pancreatitis is a rare but serious development occurring in less than 0.5% of patients treated with this drug. Severe pancreatitis with progressive abdominal distention, toxemia, hypotension and respiratory insufficiency occurred in an 18-year-old patient with acute lymphoblastic leukemia following treatment with asparaginase. There was a dramatic response to high flow peritoneal lavage with rapid recovery within 24 hours from a moribund state. The subsequent development of a pseudocyst, with progressive increase in size and development of obstructive symptoms, required surgical decompression. Transgastric cystogastrostomy was successfully carried out.
journal_name
Cancerjournal_title
Cancerauthors
Greenstein R,Nogeire C,Ohnuma T,Greenstein Adoi
10.1002/1097-0142(197902)43:2<718::aid-cncr2820430subject
Has Abstractpub_date
1979-02-01 00:00:00pages
718-22issue
2eissn
0008-543Xissn
1097-0142journal_volume
43pub_type
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