Involvement of calcium in the transient depolarization of E.coli cytoplasmic membrane induced by phage adsorption: a study with the fluorescent calcium indicator QUIN2.

abstract：PURPOSE:Cancer stem cells (CSCs), also known as tumor-initiating cells, are involved in tumor progression, metastasis, and drug resistance. Hybrid liposomes (HLs) are nano-sized liposomal particles that can be easily prepared by ultrasonicating a mixture of vesicular and micellar molecules in buffer solutions. In this ...

journal_title：Biochemical and biophysical research communications

authors： Inamura K,Komizu Y,Yamakuchi M,Ishida S,Matsumoto Y,Matsushita T

更新日期：2019-01-29 00:00:00

abstract：:alpha 2,6 sialyltransferase towards the N-acetyllactosaminyl sequence (alpha 2,6 ST, E.C. 2.4.99.1) is one of the major sialyltransferases in human colonic cells; it strongly increases in human colorectal tumors and is largely expressed in fetal and neonatal rat colon. In this study we demonstrate that human colon car...

journal_title：Biochemical and biophysical research communications

authors： Dall'Olio F,Malagolini N,Serafini-Cessi F

更新日期：1992-05-15 00:00:00

abstract：:Inspired by recent interest in torsion of the central pair microtubules in eukaryotic flagella, a novel thin-walled elastic beam model is suggested to study critical condition under which uniform bending of a flagellum will cause lateral/torsional buckling of the central pair. The model is directed to the central pair...

journal_title：Biochemical and biophysical research communications

authors： Li C,Ru CQ,Mioduchowski A

更新日期：2006-12-08 00:00:00

abstract：:Cytochrome (cyt) c can uncouple from the respiratory chain following mitochondrial stress and catalyze lipid peroxidation. Accumulating evidence shows that this phenomenon impairs mitochondrial respiratory function and also initiates the apoptotic cascade. Therefore, under certain conditions a pharmacological approach...

journal_title：Biochemical and biophysical research communications

authors： Yin H,Vergeade A,Shi Q,Zackert WE,Gruenberg KC,Bokiej M,Amin T,Ying W,Masterson TS,Zinkel SS,Oates JA,Boutaud O,Roberts LJ 2nd

更新日期：2012-06-29 00:00:00

abstract：:To study the effect of interleukin-6 (IL-6) on glucose transport, 2-deoxy-D-glucose (2-DOG) uptake in 3T3-L1 adipocytes after incubation with IL-6 was measured. IL-6 increased 2-DOG uptake maximally after 5 hours by 30 +/- 12%, with a half-maximal effect at an IL-6 concentration of approximately 800 U/mL. 3-O-methylgl...

journal_title：Biochemical and biophysical research communications

authors： Stouthard JM,Oude Elferink RP,Sauerwein HP

更新日期：1996-03-18 00:00:00

abstract：:Proteins modified by oxidants are rapidly degraded by intracellular proteases. Oxidatively modified superoxide dismutase (Ox-SOD) was degraded 2-8 times faster at both acidic and alkaline pH than the native protein in bovine cardiac tissue extracts. At acidic pH, Ox-SOD hydrolysis was stimulated by ATP and by non-hydr...

journal_title：Biochemical and biophysical research communications

authors： Strack PR,Waxman L,Fagan JM

更新日期：1996-02-15 00:00:00

abstract：BACKGROUND:DMSO is routinely infused together with hematopoietic cells in patients undergoing myeloablative therapy and was recently found to inhibit smooth muscle cells proliferation and arterial thrombus formation in the mouse by preventing tissue factor (TF), a key activator of the coagulation cascade. This study wa...

journal_title：Biochemical and biophysical research communications

authors： Asmis L,Tanner FC,Sudano I,Lüscher TF,Camici GG

更新日期：2010-01-22 00:00:00

abstract：:Polyamine biosynthesis pathway has long been considered an essential drug target for trypanosomatids including Leishmania. S-adenosylmethionine decarboxylase (AdoMetDc) and spermidine synthase (SpdSyn) are enzymes of this pathway that catalyze successive steps, with the product of the former, decarboxylated S-adenosyl...

journal_title：Biochemical and biophysical research communications

authors： Mishra AK,Agnihotri P,Srivastava VK,Pratap JV

更新日期：2015-01-09 00:00:00

abstract：:Multiple sclerosis (MS) has been documented to have various clinical and pathological presentations. However the underlying mechanisms remain unknown. Viral infections may play a certain role in the etiopathogenesis of MS. This study was designed to explore whether different phospholipid peptides and viral mimic pepti...

journal_title：Biochemical and biophysical research communications

authors： Zheng MM,Zhang XH

更新日期：2014-01-17 00:00:00

abstract：:The rat glucokinase (GK) gene containing the first exon was isolated and its 5' flanking region was characterized by the bacterial chloramphenicol acetyltransferase (CAT) assay. A transient expression assay with a series of 5' deletion constructs (-5.5 k to -48) of GK-CAT fusion genes indicated that the 5' flanking se...

journal_title：Biochemical and biophysical research communications

authors： Noguchi T,Takenaka M,Yamada K,Matsuda T,Hashimoto M,Tanaka T

更新日期：1989-11-15 00:00:00

abstract：:p73, a member of the p53 family, is a transcription factor that plays a key role in many biological processes. In the present study, we show that TAp73 is expressed in neural stem cells (NSC) and its expression increases following their differentiation. NSC from p73 null mice have a reduced proliferative potential, to...

journal_title：Biochemical and biophysical research communications

authors： Agostini M,Tucci P,Chen H,Knight RA,Bano D,Nicotera P,McKeon F,Melino G

更新日期：2010-12-03 00:00:00

abstract：:cDNA clones encoding a precursor of the alpha-subunit of the mitochondrial ATP synthase complex have been isolated from a bovine liver cDNA library using the alpha-subunit gene from Saccharomyces cerevisiae as a probe. Analyses of the nucleotide sequence of these cDNA clones reveal that the bovine liver ATP synthase a...

journal_title：Biochemical and biophysical research communications

authors： Breen GA

更新日期：1988-04-15 00:00:00

abstract：:We have determined the ability of two well-characterized eukaryotic homing endonucleases, I-PpoI from the myxomycete Physarum polycephalum and I-CreI from the green alga Chlamydomonas reinhardtii, to generate site-specific DNA double-strand breaks in human cells. These 18-kDa proteins cleave highly conserved 15- or 24...

journal_title：Biochemical and biophysical research communications

authors： Monnat RJ Jr,Hackmann AF,Cantrell MA

更新日期：1999-02-05 00:00:00

abstract：:The gene ENOD40 is expressed at an early stage of root nodule organogenesis and has been postulated to play a central regulatory role in the Rhizobium-legume interaction. In vitro translation of soybean ENOD40 mRNA showed that the gene encodes two peptides of 12 and 24aa residues (peptides A and B) that bind to sucros...

journal_title：Biochemical and biophysical research communications

authors： Röhrig H,John M,Schmidt J

更新日期：2004-12-17 00:00:00

abstract：:Designed peptides that would selectively interact with lipopolysaccharide (LPS) or endotoxin and fold into specific conformations could serve as important scaffolds toward the development of antisepsis compounds. Here, we describe solution structure of a designed amphipathic peptide, H(2)N-YVKLWRMIKFIR-CONH(2) (YW12D)...

journal_title：Biochemical and biophysical research communications

authors： Bhunia A,Chua GL,Domadia PN,Warshakoon H,Cromer JR,David SA,Bhattacharjya S

更新日期：2008-05-09 00:00:00

abstract：:Bacterial endotoxins or lipopolysaccharides (LPS), cell wall components of gram negative bacteria, are involved in septic shock. While the carbohydrate structure of LPS have been studied in the past, little is known about the macromolecular structure and formation of LPS fragments in blood. It is believed that amphiph...

journal_title：Biochemical and biophysical research communications

authors： Aurell CA,Wistrom AO

更新日期：1998-12-09 00:00:00

abstract：:The major interaction site for tumor-promoting phorbol esters is the calcium-activated, phospholipid-dependent protein kinase (protein kinase C), a key-element in signal transduction. Binding of phorbol esters results in enzyme activation which mediates, at least in part, the action of these agents. We have investigat...

journal_title：Biochemical and biophysical research communications

authors： Roghani M,Da Silva C,Castagna M

更新日期：1987-02-13 00:00:00

abstract：:A well-established feature of the translation initiation region, which attracts the ribosomes to the prokaryotic mRNAs, is a purine rich area called Shine/Dalgarno sequence (SD). There are examples of various other sequences, which despite having no similarity to an SD sequence are capable of enhancing and/or initiati...

journal_title：Biochemical and biophysical research communications

authors： Golshani A,Krogan NJ,Xu J,Pacal M,Yang XC,Ivanov I,Providenti MA,Ganoza MC,Ivanov IG,AbouHaidar MG

更新日期：2004-04-16 00:00:00

abstract：:Chlorophyllide a oxygenase (CAO) that converts chlorophyllide a to chlorophyllide b was overexpressed in tobacco to increase chlorophyll (Chl) b biosynthesis and alter the Chl a/b ratio. Transgenic plants along with their wild-type cultivars were grown in low and high light intensities. In low light there was 20% incr...

journal_title：Biochemical and biophysical research communications

authors： Pattanayak GK,Biswal AK,Reddy VS,Tripathy BC

更新日期：2005-01-14 00:00:00

abstract：:pp120, a plasma membrane glycoprotein, is phosphorylated on Tyr488 by the insulin receptor tyrosine kinase. This requires basal phosphorylation on Ser503 by cAMP-dependent serine kinase. Phe513, the other tyrosine residue in the intracellular domain, does not undergo insulin-stimulated phosphorylation. Phe488 mutation...

journal_title：Biochemical and biophysical research communications

authors： Najjar SM

更新日期：1998-06-18 00:00:00

abstract：:Secretion of growth hormone (GH) exhibits marked sexual dimorphism in the rat. To examine the underlying mechanism that involves hypothalamic GH-releasing factor (GRF), we determined pituitary GRF receptor mRNA levels in male and female rats and compared their in vitro abilities to release GRF, an endogenous ligand fo...

journal_title：Biochemical and biophysical research communications

authors： Ono M,Miki N,Murata Y,Osaki E,Tamitsu K,Ri T,Yamada M,Demura H

更新日期：1995-11-22 00:00:00

abstract：:The N-terminal leucine residue of snake venom cardiotoxin II (CTX II) (Naja naja atra) was systematically replaced with D-leucine (CTXII-L1-D-L), glycine (CTXII-L1G) or deleted [CTXII-(2-60)] to study the role of leucine residue in CTX II molecule. CTX II, CTXL1-D-L, CTXL1G and CTX(2-60) were produced by chemical synt...

journal_title：Biochemical and biophysical research communications

authors： Wu CY,Chen WC,Ho CL,Chen ST,Wang KT

更新日期：1997-04-28 00:00:00

abstract：:The aim of this study was to investigate the possible pathological relation between mechanical stress and hyperpigmentation. We did this by investigating the influence of cyclic stretch on the expression of keratinocyte- and fibroblast-derived melanogenetic paracrine cytokines in vitro. Using primary human keratinocyt...

journal_title：Biochemical and biophysical research communications

authors： Kurita M,Okazaki M,Fujino T,Takushima A,Harii K

更新日期：2011-05-27 00:00:00

abstract：:Unc104/KIF1A, a kinesin family member, is reported to be monomeric in solution, though its polypeptide has regions that potentially form coiled coils. For a better understanding of the mechanism underlying Unc104/KIF1A's motility, it is important to evaluate the dimerization ability of this protein. The CD measurement...

journal_title：Biochemical and biophysical research communications

authors： Shimizu Y,Morii H,Arisaka F,Tanokura M

更新日期：2005-11-25 00:00:00

abstract：:Glioblastomas are highly invasive and aggressive primary brain tumors. Type I interferons have significant, pleiotropic anticancer activity. However, through various pathways many cancers become interferon-resistant, limiting interferon's clinical utility. In this study, we demonstrated that the proteasomal inhibitor ...

journal_title：Biochemical and biophysical research communications

authors： Wang R,Davidoff AM,Pfeffer LM

更新日期：2016-09-09 00:00:00

abstract：:We have previously reported the identification of two closely related RNA binding proteins from Trypanosoma brucei which we have termed p34 and p37. The predicted primary structures of the two proteins are highly homologous with one major difference, an 18-amino-acid insert in the N-terminal region of p37. These two p...

journal_title：Biochemical and biophysical research communications

authors： Pitula J,Ruyechan WT,Williams N

更新日期：2002-01-11 00:00:00

abstract：:Cytosolic prostaglandin (PG) E synthase (cPGES) is constitutively expressed in various cells and regulates cyclooxygenase (COX)-1-dependent immediate PGE(2) generation. Its primary structure is identical to co-chaperone p23, a heat shock protein 90 (Hsp90)-binding protein. We have revealed that Hsp90 regulated both cP...

journal_title：Biochemical and biophysical research communications

authors： Nakatani Y,Hokonohara Y,Kakuta S,Sudo K,Iwakura Y,Kudo I

更新日期：2007-10-19 00:00:00

abstract：:To elucidate the role of ornithine decarboxylase (ODC) in cancer cell invasion, we have compared the invasiveness of mouse mammary carcinoma, FM3A and its variant cell line, EXOD, which overproduces ODC. We have found that EXOD cells showed about 5.6-fold more invasiveness through a reconstituted basement membrane (Ma...

journal_title：Biochemical and biophysical research communications

authors： Kubota S,Yamada T,Kamei S,Seyama Y

更新日期：1995-03-28 00:00:00

abstract：OBJECTIVE:To evaluate protein profiles and Fc gamma receptor IIb (FCGRIIB) expression in abdominal aortic aneurysm (AAA) compared to the expression in normal aortas. METHODS:We performed a protein array to study the protein expression profiles within AAA and normal aortic tissues. FCGRIIB was found to be significantly...

journal_title：Biochemical and biophysical research communications

authors： Shi Y,Yang CQ,Wang SW,Li W,Li J,Wang SM

更新日期：2017-04-01 00:00:00

abstract：:The physical and catalytic properties of 5 histidine-serine mutants of human 5-lipoxygenase (5-LO) have been characterized. The mutants HS363, HS391 and HS400 have activities, pH optima and stabilities similar to those of the wild type enzyme. The iron content of each of these mutants is 0.30-0.53 mol Fe/mol 5-LO whic...

journal_title：Biochemical and biophysical research communications

authors： Percival MD,Ouellet M

更新日期：1992-08-14 00:00:00