Fast mapping of myocardial blood flow with MR first-pass perfusion imaging.

Abstract:

:Accurate and fast quantification of myocardial blood flow (MBF) with MR first-pass perfusion imaging techniques on a pixel-by-pixel basis remains difficult due to relatively long calculation times and noise-sensitive algorithms. In this study, Zierler's central volume principle was used to develop an algorithm for the calculation of MBF with few assumptions on the shapes of residue curves. Simulation was performed to evaluate the accuracy of this algorithm in the determination of MBF. To examine our algorithm in vivo, studies were performed in nine normal dogs. Two first-pass perfusion imaging sessions were performed with the administration of the intravascular contrast agent Gadomer at rest and during dipyridamole-induced vasodilation. Radiolabeled microspheres were injected to measure MBF at the same time. MBF measurements in dogs using MR methods correlated well with the microsphere measurements (R2=0.96, slope=0.9), demonstrating a fair accuracy in the perfusion measurements at rest and during the vasodilation stress. In addition to its accuracy, this method can also be optimized to run relatively fast, providing potential for fast and accurate myocardial perfusion mapping in a clinical setting.

journal_name

Magn Reson Med

authors

Goldstein TA,Jerosch-Herold M,Misselwitz B,Zhang H,Gropler RJ,Zheng J

doi

10.1002/mrm.21559

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

1394-400

issue

6

eissn

0740-3194

issn

1522-2594

journal_volume

59

pub_type

杂志文章
  • Proton high-resolution magic angle spinning NMR analysis of fresh and previously frozen tissue of human prostate.

    abstract::The previously observed improvement in spectral resolution of tissue proton NMR with high-resolution magic angle spinning (HRMAS) was speculated to be due largely to freeze-thawing artifacts resulting from tissue storage. In this study, 12 human prostate samples were analyzed on a 14.1T spectrometer at 3 degrees C, wi...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10645

    authors: Wu CL,Taylor JL,He W,Zepeda AG,Halpern EF,Bielecki A,Gonzalez RG,Cheng LL

    更新日期:2003-12-01 00:00:00

  • Incorporation of Rician noise in the analysis of biexponential transverse relaxation in cartilage using a multiple gradient echo sequence at 3 and 7 Tesla.

    abstract:PURPOSE:Previous work has evaluated the quality of different analytic methods for extracting relaxation times from magnitude imaging data exhibiting Rician noise. However, biexponential analysis of relaxation in tissue, including cartilage, and materials is of increasing interest. We, therefore, analyzed biexponential ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25111

    authors: Bouhrara M,Reiter DA,Celik H,Bonny JM,Lukas V,Fishbein KW,Spencer RG

    更新日期:2015-01-01 00:00:00

  • 31P nuclear magnetic resonance study of acute renal dysfunction in rat kidney transplants.

    abstract::31P NMR spectroscopy was used to study renal allografts in rats subjected to allograft rejection, cyclosporine toxicity, ischemia, and ureteral obstruction. Parameters of relative peak areas and intracellular pH were accurately distinguished among the different causes of graft dysfunction. Ureteral obstruction was cle...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910050405

    authors: Shapiro JI,Haug CE,Weil R 3rd,Chan L

    更新日期:1987-10-01 00:00:00

  • Effect of lanthanide ions on dynamic nuclear polarization enhancement and liquid-state T1 relaxation.

    abstract::In the dynamic nuclear polarization process, microwave irradiation facilitates exchange of polarization from a radical's unpaired electron to nuclear spins at cryogenic temperatures, increasing polarization by >10,000. Doping samples with Gd(3+) ions further increases the achievable solid-state polarization. However, ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24207

    authors: Gordon JW,Fain SB,Rowland IJ

    更新日期:2012-12-01 00:00:00

  • Use of a projection reconstruction method to decrease motion sensitivity in diffusion-weighted MRI.

    abstract::Diffusion-weighted MRI is a clinically useful technique, but its utility is compromised by high sensitivity to patient motion. Use of radial-scan data acquisition and projection reconstruction, rather than the conventional Fourier imaging method, can substantially reduce the sensitivity to global translational motion ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910290619

    authors: Gmitro AF,Alexander AL

    更新日期:1993-06-01 00:00:00

  • B factor dependence of the temporal characteristics of brain activation using dynamic apparent diffusion coefficient contrast.

    abstract::Functional MRI studies to date have been generally performed using the blood oxygenation level dependent (BOLD) contrast mechanism. Recently, it has been proposed that dynamic change in the apparent diffusion coefficient (ADC), measured using intravoxel incoherent motion (IVIM) weighting, can be used as a robust funct...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20293

    authors: Harshbarger TB,Song AW

    更新日期:2004-12-01 00:00:00

  • Automatic vessel removal in gliomas from dynamic susceptibility contrast imaging.

    abstract::The presence of macroscopic vessels within the tumor region is a potential confounding factor in MR-based dynamic susceptibility contrast (DSC)-enhanced glioma grading. In order to distinguish between such vessels and the elevated cerebral blood volume (CBV) of brain tumors, we propose a vessel segmentation technique ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21944

    authors: Emblem KE,Due-Tonnessen P,Hald JK,Bjornerud A

    更新日期:2009-05-01 00:00:00

  • The fast spiral-SelMQC technique for in vivo MR spectroscopic imaging of polyunsaturated fatty acids in human breast tissue.

    abstract::The selective multiple-quantum coherence transfer method has been applied to image polyunsaturated fatty acids (PUFA) distributions in human breast tissues in vivo for cancer detection, with complete suppression of the unwanted lipid and water signals in a single scan. The Cartesian k-space mapping of PUFA in vivo usi...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22901

    authors: Zhu H,Rubin D,He Q

    更新日期:2012-01-01 00:00:00

  • Manganese-enhanced MRI of salivary glands and head and neck tumors in living subjects.

    abstract::Manganese-enhanced MRI has previously been used for visualization of brain architecture and functional mapping of neural pathways. The present work investigated the potential of manganese-enhanced MRI for noninvasive imaging of salivary glands in living subjects. Marked shortening of T(1) was observed in salivary glan...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22452

    authors: Seshadri M,Hoy A

    更新日期:2010-09-01 00:00:00

  • Infimal convolution of total generalized variation functionals for dynamic MRI.

    abstract:PURPOSE:To accelerate dynamic MR applications using infimal convolution of total generalized variation functionals (ICTGV) as spatio-temporal regularization for image reconstruction. THEORY AND METHODS:ICTGV comprises a new image prior tailored to dynamic data that achieves regularization via optimal local balancing b...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26352

    authors: Schloegl M,Holler M,Schwarzl A,Bredies K,Stollberger R

    更新日期:2017-07-01 00:00:00

  • Convex gradient optimization for increased spatiotemporal resolution and improved accuracy in phase contrast MRI.

    abstract:PURPOSE:To evaluate convex gradient optimization (CVX) for increased spatiotemporal resolution and improved accuracy for phase-contrast MRI (PC-MRI). METHODS:A conventional flow-compensated and flow-encoded (FCFE) PC-MRI sequence was compared with a CVX PC-MRI sequence using numerical simulations, flow phantom experim...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25059

    authors: Middione MJ,Wu HH,Ennis DB

    更新日期:2014-12-01 00:00:00

  • Quantification of vessel wall motion and cyclic strain using cine phase contrast MRI: in vivo validation in the porcine aorta.

    abstract::Artery wall motion and strain play important roles in vascular remodeling and may be important in the pathogenesis of vascular disease. In vivo observations of circumferentially nonuniform wall motion in the human aorta suggest that nonuniform strain may contribute to the localization of vascular pathology. A velocity...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20137

    authors: Draney MT,Arko FR,Alley MT,Markl M,Herfkens RJ,Pelc NJ,Zarins CK,Taylor CA

    更新日期:2004-08-01 00:00:00

  • Correction of chemical-shift artifacts in 19F imaging of PFOB: a robust signed magnitude method.

    abstract::This paper describes a method for correcting the chemical-shift artifacts in 19F NMR imaging of perfluoroctylbromide emulsion (PFOB) by utilizing the two spectral peaks of PFOB which have a long T2 value in conjunction with the Dixon method. Corrected images are obtained from the magnitude of the measured images using...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910230206

    authors: Lee HK,Nalcioglu O,Buxton RB

    更新日期:1992-02-01 00:00:00

  • Independent component analysis applied to diffusion tensor MRI.

    abstract::The accuracy of the outcome in a diffusion tensor imaging (DTI) experiment depends on the acquisition scheme as well as the postprocessing methods used. In the present study, the DTI results acquired after applying different combinations of diffusion-weighted (DW) gradient orientations were initially compared. Then, s...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10046

    authors: Arfanakis K,Cordes D,Haughton VM,Carew JD,Meyerand ME

    更新日期:2002-02-01 00:00:00

  • 3D image-based navigators for coronary MR angiography.

    abstract:PURPOSE:To develop a method for acquiring whole-heart 3D image-based navigators (iNAVs) with isotropic resolution for tracking and correction of localized motion in coronary magnetic resonance angiography (CMRA). METHODS:To monitor motion in all regions of the heart during a free-breathing scan, a variable-density con...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26269

    authors: Addy NO,Ingle RR,Luo J,Baron CA,Yang PC,Hu BS,Nishimura DG

    更新日期:2017-05-01 00:00:00

  • MR-guided interstitial cryotherapy of the liver with a novel, nitrogen-cooled cryoprobe.

    abstract::The purpose of the study was to test a newly developed, MR-compatible, liquid nitrogen-cooled cryoprobe. The probe has an outer diameter of 3.5 mm and was specifically developed for percutaneous, MR-guided, interstitial cryotherapy. The probe was inserted percutaneously into the livers of 10 rabbits. The cryotherapy p...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910390304

    authors: Tacke J,Adam G,Speetzen R,Brucksch K,Bücker A,Heshel I,Prescher A,van Vaals JJ,Hunter DW,Rau G,Günther RW

    更新日期:1998-03-01 00:00:00

  • Fast measurement of relaxation times by steady-state free precession of 129Xe in carrier agents for hyperpolarized noble gases.

    abstract::Hyperpolarized gases ((129)Xe and (3)He) are being used increasingly in both MRI and NMR spectroscopy studies. However, it has been shown that carrier agents are required to preserve the long relaxation times of gases in biological fluids. Optimized gas transport can be achieved through controlled T(1) and T(2) measur...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10476

    authors: Oregioni A,Parizel N,de Sousa PL,Grucker D

    更新日期:2003-06-01 00:00:00

  • pH mapping in living tissues: an application of in vivo 31P NMR chemical shift imaging.

    abstract::Chemical shifts were extracted from in vivo 3-dimensional 31P NMR CSI data and pH images were constructed. The images could spatially resolve tissue pH ranging from 5.8 to 7.2 (with uncertainty of 0.11-0.17 pH unit) in an ischemia-reperfusion model of diabetic rat calf muscles. ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910290214

    authors: Morikawa S,Inubushi T,Kito K,Kido C

    更新日期:1993-02-01 00:00:00

  • Development and validation of 3D MP-SSFP to enable MRI in inhomogeneous magnetic fields.

    abstract:PURPOSE:We demonstrate the feasibility of MRI with missing-pulse steady-state free precession (MP-SSFP) in a 4T magnet with artificially degraded homogeneity. METHODS:T1 , T2 , and diffusion contrast of MP-SSFP was simulated with constant and alternate radiofrequency (RF) phase using an extended phase graph. To valida...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.28469

    authors: Kobayashi N,Parkinson B,Idiyatullin D,Adriany G,Theilenberg S,Juchem C,Garwood M

    更新日期:2021-02-01 00:00:00

  • Real-time observation of transient focal ischemia and hyperemia in cat brain.

    abstract::Gradient-recalled echo-planar (T2*-weighted) imaging was used to noninvasively monitor regional blood oxygenation state changes in real time during transient episodes of focal ischemia in cat brain. Varying ischemic intervals (12 s to 30 min) were caused by middle cerebral artery occlusion. A rapid signal drop was not...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910270220

    authors: De Crespigny AJ,Wendland MF,Derugin N,Kozniewska E,Moseley ME

    更新日期:1992-10-01 00:00:00

  • Dual-polarity slice-GRAPPA for concurrent ghost correction and slice separation in simultaneous multi-slice EPI.

    abstract:PURPOSE:A ghost correction strategy for Simultaneous Multi-Slice (SMS) EPI methods that provides improved ghosting artifact reduction compared to conventional methods is presented. Conventional Nyquist ghost correction methods for SMS-EPI rely on navigator data that contain phase errors from all slices in the simultane...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27113

    authors: Hoge WS,Setsompop K,Polimeni JR

    更新日期:2018-10-01 00:00:00

  • Robust 4D flow denoising using divergence-free wavelet transform.

    abstract:PURPOSE:To investigate four-dimensional flow denoising using the divergence-free wavelet (DFW) transform and compare its performance with existing techniques. THEORY AND METHODS:DFW is a vector-wavelet that provides a sparse representation of flow in a generally divergence-free field and can be used to enforce "soft" ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25176

    authors: Ong F,Uecker M,Tariq U,Hsiao A,Alley MT,Vasanawala SS,Lustig M

    更新日期:2015-02-01 00:00:00

  • Diffusion-weighted imaging of the human optic nerve: a new approach to evaluate optic neuritis in multiple sclerosis.

    abstract::The apparent diffusion coefficient (ADC) in the optic nerve was measured from diffusion-weighted magnetic resonance imaging using an intravoxel incoherent motion (IVIM) sequence. The subjects were seven normal volunteers and eight patients with multiple sclerosis (MS) with a total of four optic nerves with acute neuri...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910380317

    authors: Iwasawa T,Matoba H,Ogi A,Kurihara H,Saito K,Yoshida T,Matsubara S,Nozaki A

    更新日期:1997-09-01 00:00:00

  • Reducing oblique flow effects in interleaved EPI with a centric reordering technique.

    abstract::Segmented interleaved echo planar imaging offers a fast and efficient approach to magnetic resonance angiography. Unfortunately, this technique is particularly sensitive to oblique flow in the imaging plane. In this work, a mathematical analysis of oblique flow effects for several types of k-space coverage is presente...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1084

    authors: Beck G,Li D,Haacke EM,Noll TG,Schad LR

    更新日期:2001-04-01 00:00:00

  • Semiautomated spleen volumetry with diffusion-weighted MR imaging.

    abstract::In this article, we determined the relative accuracy of semiautomated spleen volumetry with diffusion-weighted (DW) MR images compared to standard manual volumetry with DW-MR or CT images. Semiautomated spleen volumetry using simple thresholding followed by 3D and 2D connected component analysis was performed with DW-...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.23204

    authors: Lee J,Kim KW,Lee H,Lee SJ,Choi S,Jeong WK,Kye H,Song GW,Hwang S,Lee SG

    更新日期:2012-07-01 00:00:00

  • Optimized 3D ultrashort echo time pulmonary MRI.

    abstract:PURPOSE:To optimize 3D radial ultrashort echo time MRI for high resolution whole-lung imaging. METHODS:3D radial ultrashort echo time was implemented on a 3T scanner to investigate the effects of: (1) limited field-of-view excitation, (2) variable density readouts, and (3) radial oversampling. Improvements in noise pe...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24570

    authors: Johnson KM,Fain SB,Schiebler ML,Nagle S

    更新日期:2013-11-01 00:00:00

  • A flexible fast spin echo triple-echo Dixon technique.

    abstract:PURPOSE:To develop a flexible fast spin echo (FSE) triple-echo Dixon (FTED) technique. METHODS:An FSE pulse sequence was modified by replacing each readout gradient with three fast-switching bipolar readout gradients with minimal interecho dead time. The corresponding three echoes were used to generate three raw image...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26186

    authors: Son JB,Hwang KP,Madewell JE,Bayram E,Hazle JD,Low RN,Ma J

    更新日期:2017-03-01 00:00:00

  • Data-driven optimized flip angle selection for T1 estimation from spoiled gradient echo acquisitions.

    abstract:PURPOSE:Define criteria for selection of optimal flip angle sets for T1 estimation and evaluate effects on T1 mapping. THEORY AND METHODS:Flip angle sets for spoiled gradient echo-based T1 mapping were selected by minimizing T1 estimate variance weighted by the joint density of M0 and T1 in an initial acquisition. The...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25920

    authors: Lewis CM,Hurley SA,Meyerand ME,Koay CG

    更新日期:2016-09-01 00:00:00

  • Mapping connectomes with diffusion MRI: deterministic or probabilistic tractography?

    abstract:PURPOSE:Human connectomics necessitates high-throughput, whole-brain reconstruction of multiple white matter fiber bundles. Scaling up tractography to meet these high-throughput demands yields new fiber tracking challenges, such as minimizing spurious connections and controlling for gyral biases. The aim of this study ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27471

    authors: Sarwar T,Ramamohanarao K,Zalesky A

    更新日期:2019-02-01 00:00:00

  • A 32-channel lattice transmission line array for parallel transmit and receive MRI at 7 tesla.

    abstract::Transmit and receive RF coil arrays have proven to be particularly beneficial for ultra-high-field MR. Transmit coil arrays enable such techniques as B(1) (+) shimming to substantially improve transmit B(1) homogeneity compared to conventional volume coil designs, and receive coil arrays offer enhanced parallel imagin...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22413

    authors: Adriany G,Auerbach EJ,Snyder CJ,Gözübüyük A,Moeller S,Ritter J,Van de Moortele PF,Vaughan T,Uğurbil K

    更新日期:2010-06-01 00:00:00