Plant viruses as biotemplates for materials and their use in nanotechnology.

Abstract:

:In recent years, plant virus capsids, the protein shells that form the surface of a typical plant virus particle, have emerged as useful biotemplates for material synthesis. All virus capsids are assembled from virus-coded protein subunits. Many plant viruses assemble capsids with precise 3D structures providing nanoscale architectures that are highly homogeneous and can be produced in large quantities. Capsids are amenable to both genetic and chemical modifications allowing new functions to be incorporated into their structure by design. The three capsid surfaces, the interior surface, the exterior surface, or the interface between coat protein subunits, can be independently functionalized to produce multifunctional biotemplates. In this review, we examine the recent advances in using plant virus capsids as biotemplates for nanomaterials and their potential for applications in nanotechnology, especially medicine.

journal_name

Annu Rev Phytopathol

authors

Young M,Willits D,Uchida M,Douglas T

doi

10.1146/annurev.phyto.032508.131939

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

361-84

eissn

0066-4286

issn

1545-2107

pii

10.1146/annurev.phyto.032508.131939

journal_volume

46

pub_type

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