Mechanisms and evolution of virulence in oomycetes.

Abstract:

:Many destructive diseases of plants and animals are caused by oomycetes, a group of eukaryotic pathogens important to agricultural, ornamental, and natural ecosystems. Understanding the mechanisms underlying oomycete virulence and the genomic processes by which those mechanisms rapidly evolve is essential to developing effective long-term control measures for oomycete diseases. Several common mechanisms underlying oomycete virulence, including protein toxins and cell-entering effectors, have emerged from comparing oomycetes with different genome characteristics, parasitic lifestyles, and host ranges. Oomycete genomes display a strongly bipartite organization in which conserved housekeeping genes are concentrated in syntenic gene-rich blocks, whereas virulence genes are dispersed into highly dynamic, repeat-rich regions. There is also evidence that key virulence genes have been acquired by horizontal transfer from other eukaryotic and prokaryotic species.

journal_name

Annu Rev Phytopathol

authors

Jiang RH,Tyler BM

doi

10.1146/annurev-phyto-081211-172912

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

295-318

eissn

0066-4286

issn

1545-2107

journal_volume

50

pub_type

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