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Rapid assessment of regional and global left ventricular function using three-dimensional k-t BLAST imaging.

Abstract：

OBJECTIVE:To test if three-dimensional (3D) cine spatial frequency-temporal frequency Broad-use Linear Acquisition Speed-up Technique (k-t BLAST) is suitable for rapid evaluation of global and regional left ventricular (LV) functional parameters and to evaluate the influence of gadolinium administration. MATERIALS AND METHODS:Parameters describing global and regional LV function were evaluated in 50 subjects using a two-dimensional (2D) steady-state free precession (SSFP) and pre- and postcontrast 3D k-t BLAST techniques. Data analyses included contrast-to-noise ratio analyses, and statistical evaluations included Bland-Altman, Cohen's kappa and analysis of variance techniques. RESULTS:Bland-Altman analyses revealed that the ejection fraction computed using the 3D k-t BLAST sequences before (bias+/-2S.D., 2.2+/-8.8) and after contrast administration (bias+/-2S.D., 2.7+/-7.6 mol) was comparable to the 2D SSFP technique. Similar agreement was noted for other global LV parameters. The myocardium-to-blood contrast in the apical slices was better in the 3D k-t BLAST sequence after contrast administration than before. Cohen's kappa values demonstrated good agreement between the sequences for evaluating regional wall motion. CONCLUSIONS:3D k-t BLAST can yield global and regional LV functional parameters comparable to those of the 2D SSFP technique in substantially shorter scan times. In 3D k-t BLAST images, myocardium-to-blood contrast in the apical slices is better after contrast administration.

journal_name

Magn Reson Imaging

journal_title

Magnetic resonance imaging

authors

Huber S,Muthupillai R,Mojibian H,Cheong B,Kouwenhoven M,Flamm SD

doi

10.1016/j.mri.2008.01.027

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

727-38

issue

6

eissn

0730-725X

issn

1873-5894

pii

S0730-725X(08)00053-2

journal_volume

26

pub_type

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