FPL 57787 and migraine prophylaxis. A double-blind cross-over study.

Abstract:

:In a double-blind cross-over trial with placebo, FPL 57787, a chromone derivate, was tested on 15 patients as a prophylactic against migraine. There was found to be no effect.

journal_name

Acta Neurol Scand

authors

Koch-Henriksen N,Sehested P

doi

10.1111/j.1600-0404.1979.tb02923.x

subject

Has Abstract

pub_date

1979-03-01 00:00:00

pages

154-5

issue

2-3

eissn

0001-6314

issn

1600-0404

journal_volume

59

pub_type

临床试验,杂志文章
  • Effect of temporary clipping on frontal lobe functions in patients with ruptured aneurysm of the anterior communicating artery.

    abstract:BACKGROUND:After surgery for ruptured anterior communicating artery (ACoA) aneurysm, several patients who have achieved a favorable neurological outcome yet have been observed to suffer from a poor cognitive outcome. The aim of this study was to explore the possible effects of temporary clip applications on frontal lob...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0404.2005.00483.x

    authors: Akyuz M,Erylmaz M,Ozdemir C,Goksu E,Ucar T,Tuncer R

    更新日期:2005-11-01 00:00:00

  • Effects of high-dose methylprednisolone on Na(+)-K+ ATPase and lipid peroxidation after experimental subarachnoid hemorrhage.

    abstract::The production of oxygen-free radicals and their subsequent peroxidative action on membrane unsaturated fatty acids could be enhanced after subarachnoid hemorrhage. High-dose methylprednisolone (30 mg/Kg i.v.) treatment can antagonize acute SAH-induced brain hypoperfusion and protect the ultrastructural integrity of e...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1990.tb01617.x

    authors: Marzatico F,Gaetani P,Buratti E,Messina AL,Ferlenga P,Rodriguez y Baena R

    更新日期:1990-10-01 00:00:00

  • Neuropsychological deficits in asymptomatic carotid artery stenosis.

    abstract::A total of 20 subjects with asymptomatic carotid artery stenosis (ACAS) and a group of healthy controls were compared as to their cognitive performance. Subjects with ACAS showed substantial deficits on tasks of mental speed, learning, visuospatial abilities, verbal processing and deductive reasoning. The cognitive pr...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1991.tb03967.x

    authors: Benke T,Neussl D,Aichner F

    更新日期:1991-06-01 00:00:00

  • Neurofilament light protein levels in cerebrospinal fluid predict long-term disability of Guillain-Barré syndrome: A pilot study.

    abstract:OBJECTIVES:Although the recovery from Guillain-Barré syndrome (GBS) is good in most patients, some develop permanent severe disability or even die. Early predictors would increase the likelihood to identify patients at risk for poor outcome at the acute stage, allowing them intensified therapeutic intervention. MATERI...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12927

    authors: Axelsson M,Sjögren M,Andersen O,Blennow K,Zetterberg H,Lycke J

    更新日期:2018-08-01 00:00:00

  • "Chronic painter's syndrome". A reanalysis of psychological test data in a group of diagnosed cases, based on comparisons with matched controls.

    abstract::Twenty solvent-exposed workers, most of them painters, had been diagnosed as cases of toxic encephalopathy in 1978/79. Two years later they were re-examined with an extensive battery of neuropsychological tests. Their performance was unchanged on retesting. We have now compared their test results with those of non-exp...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1988.tb05913.x

    authors: Gade A,Mortensen EL,Bruhn P

    更新日期:1988-04-01 00:00:00

  • Experimental studies and controlled clinical testing of valproate and vigabatrin.

    abstract::Gamma-aminobutyric acid (GABA) is the most important inhibitory transmitter, quantitatively, in the CNS. Evidence exists that decreased GABAergic neurotransmission may play a role in some forms of epilepsy. Consequently, manipulating the GABA system may be a therapeutic possibility in the treatment of this disease. In...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章,评审

    doi:10.1111/j.1600-0404.1988.tb03655.x

    authors: Gram L

    更新日期:1988-10-01 00:00:00

  • Subjective memory decline in healthy community-dwelling elders. What does this complain mean?

    abstract:OBJECTIVES:Subjective feelings of memory decline are fairly common among the elderly. The causes of this are heterogeneous, and may be related to both affective and cognitive disorders. We attempted to explore the associations between subjective and cognitive measures. MATERIALS AND METHODS:Healthy subjects were studi...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2009.01159.x

    authors: Balash Y,Mordechovich M,Shabtai H,Merims D,Giladi N

    更新日期:2010-03-01 00:00:00

  • Enzyme-linked immunosorbent assay for detection of antibodies to extractable muscle antigens in myasthenia gravis.

    abstract::A purified citric acid soluble extract from human skeletal muscle (AEMA) and a phosphate-buffered saline extract from rabbit muscle acetone powder (EMA) were used to coat polystyrene beads in an enzyme-linked immunosorbent assay (ELISA). From 54 patients with myasthenia gravis, positive results were observed in 14. Fi...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1986.tb04606.x

    authors: Viana VS,Bueno C,Marchiori PE,Oliveira RM,Assis JL,Scaff M,Cossermelli W

    更新日期:1986-06-01 00:00:00

  • Higher incidence of Epstein-Barr virus-induced lymphocyte transformation in multiple sclerosis.

    abstract:OBJECTIVES:Epstein-Barr virus (EBV) infection is associated with multiple sclerosis (MS), and EBV may transform lymphoblastoid cell lines more frequently in MS patients than controls, but it is not clear whether this reflects a higher viral load or an enhanced ability to reactivate EBV. MATERIAL AND METHODS:MS patient...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12249

    authors: Tørring C,Andreasen C,Gehr N,Bjerg L,Petersen T,Höllsberg P

    更新日期:2014-08-01 00:00:00

  • Age at onset: the major determinant of outcome in Parkinson's disease.

    abstract::Factors at presentation which influenced the course of the disease and response to treatment were assessed in 125 de novo patients with Parkinson's disease. Ninety-eight patients were available for re-assessment at 5 years. Older patients presented earlier after the onset of symptoms, deteriorated more rapidly, and we...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1111/j.1600-0404.1995.tb00480.x

    authors: Hely MA,Morris JG,Reid WG,O'Sullivan DJ,Williamson PM,Broe GA,Adena MA

    更新日期:1995-12-01 00:00:00

  • Cerebrospinal fluid insulin-like growth factor-1, insulin growth factor binding protein-2 or nitric oxide are not increased in MS or ALS.

    abstract:OBJECTIVES:Many studies have shown that nitric oxide (NO) and growth factors including insulin growth factors (IGFs) may be involved in the pathogenesis of multiple sclerosis (MS) and neurodegenerative diseases. Our previous studies suggested a relationship between cerebrospinal fluid (CSF) NO metabolites (nitrates and...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2004.00223.x

    authors: Pirttilä T,Vanhatalo S,Turpeinen U,Riikonen R

    更新日期:2004-05-01 00:00:00

  • Advances in the pathophysiology of status epilepticus.

    abstract::Status epilepticus (SE) describes an enduring epileptic state during which seizures are unremitting and tend to be self-perpetuating. We describe the clinical phases of generalized convulsive SE, impending SE, established SE, and subtle SE. We discuss the physiological and biochemical cascades which characterize self-...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0404.2007.00803.x

    authors: Chen JW,Naylor DE,Wasterlain CG

    更新日期:2007-04-01 00:00:00

  • Cysticercosis of the cerebellopontine angle cistern mimicking epidermoid inclusion cyst.

    abstract::We report a case of a cystic lesion in the left cerebellopontine (CP) angle cistern. The magnetic resonance (MR) imaging features closely resembled an epidermoid inclusion cyst, and was interpreted as such. However, at surgery and on histopathological examination the lesion was found to be a cysticercus cyst. It may b...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1999.tb07359.x

    authors: Singh S,Gibikote SV,Bannur U,Chacko G,Korah IP,Rajshekhar V

    更新日期:1999-04-01 00:00:00

  • Valproate-associated foetal malformations-Rates of occurrence, risks in attempted avoidance.

    abstract:OBJECTIVES:To gain insight into the main advantages and disadvantages that might result from valproate being unavailable for women who intend to become pregnant. MATERIALS AND METHODS:Analysis of data from the Australian Pregnancy Register concerning pregnancies exposed to valproate (N = 501) and pregnancies where pre...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.13005

    authors: Vajda FJE,O'Brien TJ,Graham JE,Hitchcock AA,Lander CM,Eadie MJ

    更新日期:2019-01-01 00:00:00

  • Cardiovascular and renin responses to head-up tilt tests in parkinsonism.

    abstract:OBJECTIVES:We investigated cardiovascular and renin responses to head-up tilt tests in patients with Parkinson's disease (PD), multiple system atrophy (MSA), and in controls to determine variables for the assignment of parkinsonism to the potential underlying neurologic condition. PATIENTS AND METHODS:Sequential chang...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1997.tb00270.x

    authors: Plaschke M,Schwarz J,Dahlheim H,Backmund H,Trenkwalder C

    更新日期:1997-10-01 00:00:00

  • Distribution of cerebral microembolism in the anterior and middle cerebral arteries.

    abstract:BACKGROUND AND PURPOSE:Cerebral infarcts occur more frequently along the middle (MCA) than the anterior cerebral artery (ACA) territory. The reason(s) for this difference remains speculative. The objective of this study was to investigate the distribution of cerebral microemboli as detected by transcranial Doppler ultr...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2000.101002122.x

    authors: Wijman CA,Babikian VL,Winter MR,Pochay VE

    更新日期:2000-02-01 00:00:00

  • Effect of sympathetic denervation on chronic cold injuries in rabbit brain. A microangiographical and histological study.

    abstract::Sympathetic denervation of the brain vessels was performed uni- or bilaterally in 13 adult rabbits, and cortical cold lesions were induced bilaterally 10-18 days afterwards. After a further 4-35 days the vascular and morphological changes in the lesion areas were studied histologically and with angiography. No differe...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1976.tb04801.x

    authors: West KA,Hassler O

    更新日期:1976-09-01 00:00:00

  • A congenital dermal sinus presenting the muscle fasciculation and hypertrophy.

    abstract:OBJECTIVE:To report unique and unknown clinical features of muscle fasciculation and muscle hypertrophy in a case of congenital dermal sinus. PATIENTS:A 16-year-old girl presented with continuous fasciculation, often cramp, and hypertrophy of the left calf muscle. The radiography showed spina bifida of L4, L5 and S1. ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2001.103005323.x

    authors: Takahashi M,Murata H,Ohmura T,Nagano A

    更新日期:2001-05-01 00:00:00

  • Orthostatic tremor: essential and symptomatic cases.

    abstract::We studied clinically and electrophysiologically 8 patients affected by orthostatic tremor (OT), which is an unusual movement disorder consisting of shaking movements of the legs and trunk in the standing position. We failed to find any cause in 6 of the 8 cases. In 2 patients OT was clearly secondary to neurologic di...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1990.tb00944.x

    authors: Gabellini AS,Martinelli P,Gullì MR,Ambrosetto G,Ciucci G,Lugaresi E

    更新日期:1990-02-01 00:00:00

  • Antiepileptic drugs, foetal malformations and spontaneous abortions.

    abstract:BACKGROUND:Some recent studies have found an association between foetal malformations in earlier antiepileptic drug (AED)-exposed pregnancies and an increased hazard of such malformations in subsequent pregnancies. We investigated this matter further, and also considered the possible role of spontaneous abortions in pr...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12672

    authors: Vajda FJ,O'Brien TJ,Graham JE,Hitchcock AA,Lander CM,Eadie MJ

    更新日期:2017-03-01 00:00:00

  • The Gulf War era multiple sclerosis cohort: 3. Early clinical features.

    abstract:OBJECTIVES:To present clinical features at diagnosis for a large nationwide incident cohort of multiple sclerosis (MS) among those serving in the US military during the Gulf War era (GWE). MATERIALS & METHODS:Medical records and databases from the Department of Veterans Affairs (VA) for cases of MS with onset in or af...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12810

    authors: Wallin MT,Culpepper WJ,Maloni H,Kurtzke JF

    更新日期:2018-01-01 00:00:00

  • Biochemical evidence for osteomalacia with carbamazepine therapy.

    abstract::Many anticonvulsants are known to cause osteomalacia, however, carbamazepine has not previously been studied in this regard. We studied 31 patients on carbamazepine (mean dose 758 mg +/- s.d. 468 mg per day), as a single drug for epilepsy for a duration of 20.5 +/- 10 months. Three patients (10%) had hypocalcaemia, an...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1980.tb03037.x

    authors: O'Hare JA,Duggan B,O'Driscoll D,Callaghan N

    更新日期:1980-11-01 00:00:00

  • Herpes simplex virus type 2 DNA detected in cerebrospinal fluid of 9 patients with Mollaret's meningitis.

    abstract::We present clinical and virological data on 9 patients, 7 women and 2 men aged 31-56 years, with recurrent aseptic meningitis (Mollaret's meningitis). Polymerase chain reaction detected Herpes simplex virus type 2 DNA in cerebrospinal fluid samples from all patients collected during their latest attacks of meningitis....

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1998.tb07296.x

    authors: Jensenius M,Myrvang B,Størvold G,Bucher A,Hellum KB,Bruu AL

    更新日期:1998-09-01 00:00:00

  • The long-term development of non-motor problems after STN-DBS.

    abstract:OBJECTIVES:Stimulation of the subthalamic nucleus (STN-DBS) is an established treatment with long-term beneficial effects on motor symptoms in patients with Parkinson's disease (PD). The long-term development of non-motor problems after STN-DBS is not fully understood. In this study, we have studied how non-motor probl...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12391

    authors: Lilleeng B,Gjerstad M,Baardsen R,Dalen I,Larsen JP

    更新日期:2015-10-01 00:00:00

  • Cerebrospinal fluid markers in MS patients and their healthy siblings.

    abstract::In a previous study we found that nine of 47 siblings to multiple sclerosis (MS) patients with a normal neurological examination carry an intrathecal oligoclonal immunopathy with limited specificity, a condition we termed MS immunopathic trait. The purpose of this study is to further characterize the MS immunopathic t...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2003.00197.x

    authors: Haghighi S,Andersen O,Odén A,Rosengren L

    更新日期:2004-02-01 00:00:00

  • Neurophysiologic evaluation of cyclosporine toxicity associated with bone marrow transplantation.

    abstract:INTRODUCTION:Cortical blindness, a rare form of cyclosporine (CSA) neurotoxicity, has previously been described in only nine bone marrow transplant (BMT) recipients. METHODS:Our institution averages 35 allogeneic BMT's per year. In the past year we have seen two women with reversible cortical blindness secondary to CS...

    journal_title:Acta neurologica Scandinavica

    pub_type: 更正并重新发布的文章,杂志文章,评审

    doi:10.1111/j.1600-0404.1996.tb07081.x

    authors: Edwards LL,Wszolek ZK,Normand MM

    更新日期:1996-11-01 00:00:00

  • Diseases associated with multiple sclerosis and epilepsy. A population cohort study of 159,200 middle-aged, urban, native Swedes observed over 10 years (1970-79).

    abstract::A defined general population of 159,200 male and female native Swedes born in the period 1911-1940 from an urban catchment area of the then only general hospital, was followed over a decade (1970-79) with regard to in-patient hospitalization for all kinds of diagnoses. As a part of this population cohort study, multip...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Lindegård B

    更新日期:1985-04-01 00:00:00

  • The normal population distribution of PRNP codon 129 polymorphism.

    abstract:OBJECTIVES:The common prion protein gene (PRNP) codon 129 polymorphism modifies the susceptibility to and the phenotype of prion diseases. However, no truly representative normal population-based data, or data stratified according to age or gender are available on the distribution of this polymorphism. MATERIAL AND ME...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2003.00199.x

    authors: Nurmi MH,Bishop M,Strain L,Brett F,McGuigan C,Hutchison M,Farrell M,Tilvis R,Erkkilä S,Simell O,Knight R,Haltia M

    更新日期:2003-11-01 00:00:00

  • Can we face the challenge of expanding use of intravenous immunoglobulin in neurology?

    abstract::The use of high-dose polyclonal intravenous immunoglobulin (IVIG) in the treatment of autoimmune neurological diseases has expanded over the last decade. Based on controlled clinical trials IVIG can be considered currently as the first-line treatment in Guillain-Barré syndrome, chronic inflammatory demyelinating polyn...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0404.2009.01317.x

    authors: Elovaara I,Hietaharju A

    更新日期:2010-11-01 00:00:00

  • Loco-regional thrombolysis in the treatment of cerebral venous and sinus thrombosis: report of two cases.

    abstract::Although intravenous (i.v.) heparin is widely used as the first line treatment for cerebral venous and sinus thrombosis (CVST), the most appropriate therapy for this disease is still controversial. We report 2 cases of CVST who were successfully treated by means of loco-regional thrombolysis with urokinase. In the fir...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2001.00058.x

    authors: Buccino G,Scoditti U,Pini M,Menozzi R,Piazza P,Zuccoli P,Mancia D

    更新日期:2001-01-01 00:00:00