Advances in the pathophysiology of status epilepticus.

abstract：:Botulinum toxin serotype A (BoNT/A) was originally used in neurology for the treatment of dystonia and blepharospasms, but is now clinically used worldwide for the treatment of chronic migraine. Still, the possible mode of action of BoNT/A in migraine is not fully known. However, the mode of action of BoNT/A has been ...

journal_title：Acta neurologica Scandinavica

authors： Do TP,Hvedstrup J,Schytz HW

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:Although patients >80 years were excluded in RCTs for tPA treatment of acute ischemic stroke (AIS), many centers treat old patients. We wanted to examine whether age ≥80 years is an independent predictor of outcome after tPA. MATERIALS:We included 77 consecutive patients ≥80 years and 83 patients <80 years t...

journal_title：Acta neurologica Scandinavica

authors： Henriksen EH,Ljøstad U,Tveiten A,Naess H,Thomassen L,Mygland A

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVES:Strokes represent the most common etiology of epilepsy in patients over the age of 60 years, with an incidence of 2-4% occurring in different studies. MATERIALS AND METHODS:In this observational study, 1,428 patients were included who had stroke and were admitted to our Stroke Unit between the years 1996 an...

journal_title：Acta neurologica Scandinavica

authors： Benbir G,Ince B,Bozluolcay M

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVES:Epilepsia partialis continua (Kojewnikow's syndrome) can be classified into 2 groups. The 1st group had stable neurological deficit, and the 2nd group had slowly progressive neurological deficit. The latter usually manifests not tetraplegia, but hemiplegia. We describe 3 patients with epilepsia partialis con...

journal_title：Acta neurologica Scandinavica

authors： Takahashi Y,Kubota H,Fujiwara T,Yagi K,Seino M

更新日期：1997-12-01 00:00:00

abstract：INTRODUCTION:We describe bilateral optic neuropathy in a patient affected by ovarian carcinoma treated with cis-platin 160 mg/m2 and carboplatin, 640 mg/m2. The patient was followed for 1 year, when recovery appeared. The few previous descriptions of CDDP optic nerve toxicity did not report recovery. METHODS:Computeri...

journal_title：Acta neurologica Scandinavica

authors： Caraceni A,Martini C,Spatti G,Thomas A,Onofrj M

更新日期：1997-10-01 00:00:00

abstract：:Using the macrophage electrophoretic mobility (MEM) test, the in vitro effects of oleic, linoleic and arachidonic acid, as well as Naudicell oil and methyl gamma-linolenate, on lymphocyte response to various antigens (PPD, thyroid antigen and EF) were studied in patients with mutiple sclerosis, patients with other neu...

journal_title：Acta neurologica Scandinavica

authors： Field EJ,Shenton BK

更新日期：1975-08-01 00:00:00

abstract：:The present communication is devoted to investigating the possibility that in myotonic dystrophy (MyD) a decreased ATP utilization by the membrane may produce modifications in glycoprotein structure and/or in the supramolecular arrangement of some membrane proteins. The study was carried out a) by determining the memb...

journal_title：Acta neurologica Scandinavica

authors： Sandrini G,Bottiroli G,Nappi G,Balduini C,Brovelli A

更新日期：1982-06-01 00:00:00

abstract：INTRODUCTION:Risk factors for aseptic intracranial venous occlusive disease are varied but only few epidemiologic studies were performed to verify the relative importance of particular factors. PATIENTS AND METHODS:A 2-year hospital-based prospective study was conducted in two hospitals to identify the clinical charac...

journal_title：Acta neurologica Scandinavica

authors： Najim al-Din AS,Mubaidin A,Wriekat AL,Alqam M

更新日期：1994-12-01 00:00:00

abstract：:Genetic investigation of 74 patients with temporal lobe epilepsy, resistant to medication, who underwent unilateral temporal lobectomy 1960-1969. Thirty per cent had a positive family history of epilepsy; 49 per cent of other neurological diseases; and 46 per cent of major psychiatric disorders. Neither of the genetic...

journal_title：Acta neurologica Scandinavica

authors： Jensen I

更新日期：1975-11-01 00:00:00

abstract：OBJECTIVES:To investigate efficacy and safety of entacapone across phase III studies in Parkinson's disease (PD) with wearing-off symptoms. METHODS:Retrospective, pooled analysis of four phase 3 randomized, double-blind, placebo-controlled studies with entacapone. RESULTS:475 of 808 patients with PD received entacapo...

journal_title：Acta neurologica Scandinavica

authors： Kuoppamäki M,Vahteristo M,Ellmén J,Kieburtz K

更新日期：2014-10-01 00:00:00

abstract：:Three-hundred and eighty-one children born with forceps delivery and 372 with normal delivery were followed up for 4-7 years. More children in the forceps group developed seizures than in normal group, i.e. 22:10. This was statistically significant (P less than 0.05). A prolonged follow-up is necessary for further obs...

journal_title：Acta neurologica Scandinavica

authors： Maheshwari MC

更新日期：1990-06-01 00:00:00

abstract：OBJECTIVES:To analyze the correlation between blood pressure (BP) variability and leukoaraiosis (LA) amount in patients with symptomatic cerebral small-vessel disease. MATERIALS AND METHODS:We included 25 hypertensive patients: 13 with Binswanger's disease (BD) and 12 with a first-ever lacunar infarction (LI). Baselin...

journal_title：Acta neurologica Scandinavica

authors： Martí-Fàbregas J,Valencia C,Pujol J,García-Sánchez C,Roca-Cusachs A,López-Contreras J,Solé MJ,Martí-Vilalta JL

更新日期：2001-12-01 00:00:00

abstract：:L-Deprenyl, a specific monoamine oxidase subtype B inhibitor, has been reported a valuable adjunct to conventional treatment of Parkinsonism. A double-blind cross-over controlled study was performed in 19 parkinsonian patients with on-off type problems. Five mg L-Deprenyl per day reduced the number of on-off episodes....

journal_title：Acta neurologica Scandinavica

authors： Brodersen P,Philbert A,Gulliksen G,Stigård A

更新日期：1985-06-01 00:00:00

abstract：:In a previous study we found that nine of 47 siblings to multiple sclerosis (MS) patients with a normal neurological examination carry an intrathecal oligoclonal immunopathy with limited specificity, a condition we termed MS immunopathic trait. The purpose of this study is to further characterize the MS immunopathic t...

journal_title：Acta neurologica Scandinavica

authors： Haghighi S,Andersen O,Odén A,Rosengren L

更新日期：2004-02-01 00:00:00

abstract：:Many anticonvulsants are known to cause osteomalacia, however, carbamazepine has not previously been studied in this regard. We studied 31 patients on carbamazepine (mean dose 758 mg +/- s.d. 468 mg per day), as a single drug for epilepsy for a duration of 20.5 +/- 10 months. Three patients (10%) had hypocalcaemia, an...

journal_title：Acta neurologica Scandinavica

authors： O'Hare JA,Duggan B,O'Driscoll D,Callaghan N

更新日期：1980-11-01 00:00:00

abstract：:The F response can provide a measure of motoneurone excitability (MNE) and so it may be used to investigate upper motoneurone disorders. This report studies the F-wave configuration in patients with stroke to evaluate the changes of the central excitability of the motoneurones at different times after an acute cerebra...

journal_title：Acta neurologica Scandinavica

authors： Fierro B,Raimondo D,Modica A

更新日期：1990-11-01 00:00:00

abstract：:Immunoglobulin G (IgG) band patterns were investigated in cerebrospinal fluid (CSF) from 19 patients with myasthenia gravis (MG) in a search for abnormalities indicating central nervous system (CNS) involvement in this disorder. Using the isoelectric focusing (IEF) technique and antiserum immunoblotting against IgG, w...

journal_title：Acta neurologica Scandinavica

authors： Mavra M,Apostolski S,Nikolic J,Thompson EJ

更新日期：1990-03-01 00:00:00

abstract：OBJECTIVES:When the vascular disorder of the cochleovestibular system is mentioned, the diagnosis is based on exclusion of other diseases. Since arteries of the cochleovestibular system cannot be directly visualized, physicians must deduce from the vascular risk factors and the vascular lesion of other territories to t...

journal_title：Acta neurologica Scandinavica

authors： Szirmai A,Küstel M,Pánczél G,Kocher I,Répássy G,Nagy Z

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:To compare the sensitivity and specificity of isoelectric focusing (IEF) with immunofixation, agarose gel electrophoresis (AGE) and the IgG index in detecting intrathecally synthesized IgG in multiple sclerosis (MS) and in other nervous system disorders. MATERIALS AND METHODS:Cerebrospinal fluid (CSF) and se...

journal_title：Acta neurologica Scandinavica

authors： Lunding J,Midgard R,Vedeler CA

更新日期：2000-11-01 00:00:00

abstract：:We report 20 cases of right unilateral spatial neglect caused by lesions in the left cerebral hemisphere. Differences in neuropsychological symptoms and lesions sites are discussed in connection with handedness. Of the right-handed patients, 6 had severe aphasia, 4 had Gerstmann's syndrome, and 1 had pure agraphia, bu...

journal_title：Acta neurologica Scandinavica

authors： Maeshima S,Shigeno K,Dohi N,Kajiwara T,Komai N

更新日期：1992-06-01 00:00:00

abstract：:Hypothyroidism induced by anti-epileptic drug treatment gave rise to thyroid function test studies in patients treated with carbamazepine (CBZ) only. In 42 patients on long-term CBZ treatment thyroxine (T4), free T4-index (FT4I), and triiodothyronine (T3) concentrations in serum were significantly lower than in contro...

journal_title：Acta neurologica Scandinavica

authors： Strandjord RE,Aanderud S,Myking OL,Johannessen SI

更新日期：1981-02-01 00:00:00

abstract：OBJECTIVE:The aim was to investigate risk factors separately and in sum in relation to long-term mortality after arterial cerebral infarction in young adults. MATERIALS AND METHODS:Mortality in relation to the number of risk factors (smoking, hypertension, hypercholesterolemia, diabetes mellitus, myocardial infarction...

journal_title：Acta neurologica Scandinavica

authors： Naess H,Waje-Andreassen U,Nyland H

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVES:To compare intravenous phenytoin (PHT) and intravenous lacosamide (LCM) for treatment of status epilepticus after failure of the first and second drug. METHODS:We retrospectively identified patients from a large community hospital in northern Germany who had been diagnosed with SE between August 2008 and De...

journal_title：Acta neurologica Scandinavica

authors： Kellinghaus C,Berning S,Stögbauer F

更新日期：2014-05-01 00:00:00

abstract：:In 5 patients with definite or highly probable MS, unusually large hypodense plaques are seen by computerized tomography (CT scan). The active plaques all show enhancement after i.v. contrast medium injection, suggestive of blood-brain-barrier-damage, and differ from the well-known CT findings in chronic MS patients, ...

journal_title：Acta neurologica Scandinavica

authors： Lidegaard O,Gyldensted C,Juhler M,Zeeberg I

更新日期：1983-08-01 00:00:00

abstract：:A large Japanese family with probable Machado-Joseph disease (MJD) is described. Detailed neurological examination in 12 patients from 3 generations revealed variable combinations of cerebellar ataxia, ocular paresis, difficulty in eye-lid opening, bulging eyes, facial "myokymia", facial dystonia, pyramidal signs, ext...

journal_title：Acta neurologica Scandinavica

authors： Takiyama Y,Ikemoto S,Tanaka Y,Mizuno Y,Yoshida M,Yasuda N

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVES:To characterise a Swedish family with a rare hereditary myopathy with unique sarcoplasmic inclusion bodies in the muscle biopsy. MATERIALS AND METHODS:Part of the pedigree was described in 1980. Nine new members of the included and the phenotype further characterised through clinical, neurophysiological and...

journal_title：Acta neurologica Scandinavica

authors： Engvall M,Ahlberg G,Hedberg B,Edström L,Ansved T

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Presence of mild cognitive impairment (MCI) as a predictor for Parkinson's disease dementia (PDD) has been discussed from a clinical perspective. Recently, a Movement Disorder Society (MDS) commissioned Task Force published guidelines for PD-MCI. However, long-term follow-ups of the PD-MCI guidelines for the...

journal_title：Acta neurologica Scandinavica

authors： Domellöf ME,Ekman U,Forsgren L,Elgh E

更新日期：2015-08-01 00:00:00

abstract：:Epileptic seizures are refractory to treatment in approximately one-third of patients despite the recent introduction of many newer antiepileptic drugs (AEDs). Development of novel AEDs therefore remains a high priority. Perampanel is a first-in-class non-competitive selective AMPA receptor antagonist with a unique me...

journal_title：Acta neurologica Scandinavica

authors： Tsai JJ,Wu T,Leung H,Desudchit T,Tiamkao S,Lim KS,Dash A

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:Myotonic dystrophy type 1 (DM1) is caused by large expansions of cytosine-thymine-guanine (CTG)-repeats in myotonic dystrophy protein kinase (DMPK)-gene. This gene is highly polymorphic in healthy individuals. It has been proposed that expanded alleles originated from the group of large sized normal alleles....

journal_title：Acta neurologica Scandinavica

authors： Culjković B,Stojković O,Vukosavić S,Savić D,Rakocevic V,Apostolski S,Romac S

更新日期：2002-01-01 00:00:00

abstract：:We present a 47-year-old white woman who had a definitive diagnosis of systemic lupus erythematosus (SLE), and developed cerebellar ataxia of sudden onset. MR imaging showed changes characteristics of cerebellar infarct. Due to the absence of vascular risk factors and to the previous diagnosis of SLE, we postulate tha...

journal_title：Acta neurologica Scandinavica

authors： Lancman ME,Pomeraniec C,Norscini J

更新日期：1992-10-01 00:00:00