Cerebrospinal fluid insulin-like growth factor-1, insulin growth factor binding protein-2 or nitric oxide are not increased in MS or ALS.

abstract：BACKGROUND:Presence of mild cognitive impairment (MCI) as a predictor for Parkinson's disease dementia (PDD) has been discussed from a clinical perspective. Recently, a Movement Disorder Society (MDS) commissioned Task Force published guidelines for PD-MCI. However, long-term follow-ups of the PD-MCI guidelines for the...

journal_title：Acta neurologica Scandinavica

authors： Domellöf ME,Ekman U,Forsgren L,Elgh E

更新日期：2015-08-01 00:00:00

abstract：:Epileptic seizures are refractory to treatment in approximately one-third of patients despite the recent introduction of many newer antiepileptic drugs (AEDs). Development of novel AEDs therefore remains a high priority. Perampanel is a first-in-class non-competitive selective AMPA receptor antagonist with a unique me...

journal_title：Acta neurologica Scandinavica

authors： Tsai JJ,Wu T,Leung H,Desudchit T,Tiamkao S,Lim KS,Dash A

更新日期：2018-04-01 00:00:00

abstract：:Febrile seizures occurred in 14 of 155 (9%) out-patients with complex partial seizures. Twelve patients had prolonged or recurrent febrile seizures, convulsive status epilepticus or a transient postictal neurological deficit. Febrile seizures were associated with perinatal abnormalities, an earlier onset of epilepsy a...

journal_title：Acta neurologica Scandinavica

authors： Schmidt D,Tsai JJ,Janz D

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND:Subcutaneous immunoglobulin (SCIG) is effective treatment of chronic inflammatory demyelinating polyneuropathy (CIDP). Quality of life (QoL) increases following switch from intravenous administration to SCIG, but its correlation with clinical functioning is sparsely studied. AIMS OF THE STUDY:The aim of thi...

journal_title：Acta neurologica Scandinavica

authors： Ryltoft AK,Al-Zuhairy A,Sindrup SH,Andersen H,Markvardsen LK

更新日期：2020-12-01 00:00:00

abstract：:OBJECTIVES - Determine whether bilateral subthalamic nucleus stimulation (STN-DBS) in Parkinson's disease (PD) is associated with an increase in neuropeptide Y (NPY) and/or resistance to inhibition by leptin in relation to post-surgery weight gain. MATERIALS AND METHODS - This prospective study included 20 patients wh...

journal_title：Acta neurologica Scandinavica

authors： Escamilla-Sevilla F,Pérez-Navarro MJ,Muñoz-Pasadas M,Sáez-Zea C,Jouma-Katati M,Piédrola-Maroto G,Ramírez-Navarro A,Mínguez-Castellanos A

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To investigate dopamine reuptake sites (dopamine transporter) in the caudate nucleus and putamen in narcolepsy. PATIENTS AND METHODS:Ten patients with narcolepsy and 15 controls were studied with positron emission tomography. A cocaine analogue [11C]-CFT was used as a radioligand. RESULTS:The uptake of[11C]...

journal_title：Acta neurologica Scandinavica

authors： Rinne JO,Hublin C,Någren K,Helenius H,Partinen M

更新日期：2004-01-01 00:00:00

abstract：:Twenty patients with paralysis agitans took part in a double-blind, cross-over investigation of CB 154 (2-bromo-alpha-ergocryptine) and Madopar (L-Dopa + benserazid (a peripheral decarboxylase inhibitor), dose ratio 4:1). Each treatment phase lasted for 8 weeks. Modapar was found to be significantly superior to CB 154...

journal_title：Acta neurologica Scandinavica

authors： Gerlach J

更新日期：1976-03-01 00:00:00

abstract：:This study is a report of 34 cases of Guillain-Barré syndrome (GBS) observed in Bangalore (South India), an endemic area for Japanese encephalitis virus (JEV) infection. Virological and immunological findings suggested an antecedent and recent JEV infection in 21/34 patients. Nineteen patients among them showed high l...

journal_title：Acta neurologica Scandinavica

authors： Ravi V,Taly AB,Shankar SK,Shenoy PK,Desai A,Nagaraja D,Gourie-Devi M,Chandramuki A

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:Guillain-Barre syndrome (GBS) is an acute disease of the peripheral nerves and their roots. Quality of life (QoL) in the first year after acute episode of GBS is still underresearched area. The aim of our study was to investigate QoL in GBS patients during a 6-month follow-up period. METHODS:Multicentric, pr...

journal_title：Acta neurologica Scandinavica

authors： Djordjevic G,Stojanov A,Bozovic I,Berisavac I,Arsenijevic M,Lukic Rajic S,Dominovic Kovacevic A,Jovanovic D,Basta I,Peric S

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:In this study the frequency of inherited thrombophilic risk factors in a population of German CVT patients and their influence on clinical outcome were evaluated. MATERIAL AND METHODS:Twenty-five patients (age 37.1 +/- 16.3 years) with CVT were screened for inherited coagulation disorders. All participants ...

journal_title：Acta neurologica Scandinavica

authors： Stolz E,Kemkes-Matthes B,Pötzsch B,Hahn M,Kraus J,Wirbartz A,Kaps M

更新日期：2000-07-01 00:00:00

abstract：:By a rapid PCR-based method to assess the 8344 mtDNA mutation associated with MERRF disease, we have studied DNA from blood samples of 10 individuals belonging to a family spanning four generations in which one patient showed the complete MERRF phenotype, three other members were less severely affected, while the rema...

journal_title：Acta neurologica Scandinavica

authors： Piccolo G,Focher F,Verri A,Spadari S,Banfi P,Gerosa E,Mazzarello P

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVE:To determine characteristics, clinical significance, frequency, and mimics of restless legs syndrome (RLS) in a cohort of Wilson's disease (WD, n = 42/f = 18), compared to healthy, matched controls. MATERIALS AND METHODS:Structured clinical interviews (patients and caregiving family members), repeated neurol...

journal_title：Acta neurologica Scandinavica

authors： Trindade MC,Bittencourt T,Lorenzi-Filho G,Alves RC,de Andrade DC,Fonoff ET,Bor-Seng-Shu E,Machado AA,Teixeira MJ,Barbosa ER,Tribl GG

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to re-evaluate the clinical features of stroke in children, their outcome and the place of the different mechanisms, in the light of CT-scan and magnetic resonance imaging. METHODS:A 10-year review of the Dijon Childhood Neurology Clinic experience (1985-1995) identified 54 patient...

journal_title：Acta neurologica Scandinavica

authors： Giroud M,Lemesle M,Madinier G,Manceau E,Osseby GV,Dumas R

更新日期：1997-12-01 00:00:00

abstract：:Supernatants of peripheral blood lymphocytes (PBL), containing lymphokines, isolated from MS patients and healthy subjects were tested for demyelinating activity in organotypic culture of the rat cerebellum. PBL were isolated on Ficoll-paque gradient and cultures in RPMI 1640 medium for 72 h with or without phytohemag...

journal_title：Acta neurologica Scandinavica

authors： Selmaj K,Renkawek K,Alam R,Kida E,Maszewska M,Rozniecki J

更新日期：1986-09-01 00:00:00

abstract：:This study concerns the distribution of T-cell subsets as determined by specific monoclonal antibodies in 50 individuals with complex partial seizures (31) and primary generalized tonic-clonic seizures (19), and in 30 healthy controls. The epileptic group had significantly fewer circulating T4 "helper" lymphocytes and...

journal_title：Acta neurologica Scandinavica

authors： Eeg-Olofsson O,Prchal JF,Andermann F

更新日期：1985-08-01 00:00:00

abstract：:Patients with acute severe headache may have a secondary form of headache. Standard head computer tomography (CT) and cerebrospinal fluid (CSF) examination are often performed in the absence of neurological deficits to exclude subarachnoid hemorrhage (SAH). Increasingly, patients undergo subsequent CT angiography (CTA...

journal_title：Acta neurologica Scandinavica

authors： Alons IM,van den Wijngaard IR,Verheul RJ,Lycklama à Nijeholt G,Wermer MJ,Algra A,Jellema K

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Recognition of stroke symptoms and activation of emergency services are essential in minimizing delay for acute stroke treatments. In this study, we assessed public stroke awareness in Sweden. METHODS:One thousand and five hundred residents aged 18-79 years participated in a telephone survey. Open-...

journal_title：Acta neurologica Scandinavica

authors： Nordanstig A,Jood K,Rosengren L

更新日期：2014-12-01 00:00:00

abstract：:A total of 24 asymptomatic HIV-infected patients (CDC II/III) and 27 HIV-negative controls were tested for speed of reaction and for general neuropsychological functioning. Reaction time was assessed with two computerized tests with differing levels of cognitive complexity. The results show that the asymptomatic HIV-p...

journal_title：Acta neurologica Scandinavica

authors： Karlsen NR,Reinvang I,Frøland SS

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:The epidemiology, diagnosis, and treatment of motor neuron disease (MND) in Chinese patients are ill known. METHODS:A registered study of 461 MND patients was conducted across 10 facilities in 7 Chinese cities from February 2009 to March 2010. RESULTS:Patients were classified as amyotrophic lateral scleros...

journal_title：Acta neurologica Scandinavica

authors： Cui F,Liu M,Chen Y,Huang X,Cui L,Fan D,Pu C,Lu J,Zhou D,Zhang C,Yan C,Li C,Ding X,Liu Y,Li X,Jiang Y,Zhang J,Shang H,Yao X,Ding Y,Niu Q,Wang L

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Delayed-release dimethyl fumarate (DMF) treatment can be associated with reduced lymphocyte and leucocyte counts, which might persist after DMF discontinuation. CASE PRESENTATION:We report the case of a patient with severe disease reactivation despite prolonged lymphopenia after DMF discontinuation. We desc...

journal_title：Acta neurologica Scandinavica

authors： Zecca C,Antozzi CG,Torri Clerici V,Ferrazzini M,Mantegazza RE,Rossi S,Gobbi C

更新日期：2018-06-01 00:00:00

abstract：:The relation between angiographically determined cerebral vasospasm following a subarachnoid hemorrhage and regional cerebral blood flow (CBF) was studied in 63 investigations of 45 patients. The CBF was measured using the intra-arterial 133-Xe clearance technique within one hour of angiography. A positive correlation...

journal_title：Acta neurologica Scandinavica

authors： Jakobsen M,Overgaard J,Marcussen E,Enevoldsen EM

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVES:Interindividual variability in intestinal absorption and bioavailability might contribute to inadequate control of seizures under treatment with carbamazepine and phenytoin. We therefore correlated intestinal expression levels and genetics of CYP3A4, CYP2C9/19, MDR1 and MRP2 with dose requirement and plasma ...

journal_title：Acta neurologica Scandinavica

authors： Simon C,Stieger B,Kullak-Ublick GA,Fried M,Mueller S,Fritschy JM,Wieser HG,Pauli-Magnus C

更新日期：2007-04-01 00:00:00

abstract：:3 patients with the condition of "painful legs and moving toes" are reported. The etiology was unknown in 2 of them, but in 1 patient the symptoms were temporarily relieved by surgery for a lumbar herniated disc. The movements restarted 6 months after surgery. EMG studies showed near rhythmical muscle action potential...

journal_title：Acta neurologica Scandinavica

authors： Wulff CH

更新日期：1982-08-01 00:00:00

abstract：:We have quantified the pattern of electrical muscle activity at a force of 0.3 kg, 30% of maximum force, and maximum force in the abductor pollicis brevis muscle of 21 patients with neurogenic disorders (10 with carpal tunnel syndrome, 9 with polyneuropathy and 2 with motor neurone disease) and of 15 normal subjects. ...

journal_title：Acta neurologica Scandinavica

authors： Bril V,Fuglsang-Frederiksen A

更新日期：1984-09-01 00:00:00

abstract：:A CSF Poly(C)-avid ribonuclease (RNase) activity was determined in serum and CSF of 11 controls and 75 neurological patients (34 multiple sclerosis (MS), 18 infectious processes and 23 other neurological diseases (OND]. In controls, the blood-CSF ratio of RNase activity is low. This fact and the absence of correlation...

journal_title：Acta neurologica Scandinavica

authors： Allinquant B,Musenger C,Schuller E

更新日期：1984-07-01 00:00:00

abstract：:Alzheimer's disease (AD) and vascular dementia (VD) are the two most common causes of dementia. As yet, no definitive biological antemortem marker has been established for differential diagnosis of AD or VD. In this study, proteins of cerebrospinal fluid (CSF) from AD, VD and control patients were analyzed by two-dime...

journal_title：Acta neurologica Scandinavica

authors： Mattila KM,Pirttilä T,Blennow K,Wallin A,Viitanen M,Frey H

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVES:To evaluate the long-term neuropsychological effects and magnetic resonance imaging (MRI) findings among retired patients with a history of exposure to carbon disulfide (CS2). MATERIAL AND METHODS:Seventy-four patients with a history of exposure to CS2 were divided into two equal groups according to their l...

journal_title：Acta neurologica Scandinavica

authors： Cho SK,Kim RH,Yim SH,Tak SW,Lee YK,Son MA

更新日期：2002-11-01 00:00:00

abstract：:We present a 47-year-old white woman who had a definitive diagnosis of systemic lupus erythematosus (SLE), and developed cerebellar ataxia of sudden onset. MR imaging showed changes characteristics of cerebellar infarct. Due to the absence of vascular risk factors and to the previous diagnosis of SLE, we postulate tha...

journal_title：Acta neurologica Scandinavica

authors： Lancman ME,Pomeraniec C,Norscini J

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVES:A confident and accurate diagnosis of multiple sclerosis (MS) is important, but a specific diagnostic test for the disease does not exist. The traditional diagnostic criteria of Poser et al. were published in 1983, and recently, McDonald et al. recommended new criteria for the diagnosis of MS. PATIENTS AND ...

journal_title：Acta neurologica Scandinavica

authors： Fangerau T,Schimrigk S,Haupts M,Kaeder M,Ahle G,Brune N,Klinkenberg K,Kotterba S,Möhring M,Sindern E,Multiple Sclerosis Study Group.

更新日期：2004-06-01 00:00:00

abstract：:The effects of L-threo-3,4-dihydroxyphenylserine (L-threo-DOPS), an unnatural norepinephrine precursor, on alpha 2-adrenergic receptors in platelet membranes were investigated in a patient with familial amyloidotic polyneuropathy, two patients with multiple system atrophy, and two patients with Parkinson's disease. Ea...

journal_title：Acta neurologica Scandinavica

authors： Azuma T,Suzuki T,Sakoda S,Mizuno R,Tsujino S,Kobayashi T,Kishimoto S,Hiraga T,Matsubara T,Yoshida S

更新日期：1991-07-01 00:00:00