Severe multiple sclerosis reactivation during prolonged lymphopenia after dimethyl fumarate discontinuation.

abstract：OBJECTIVES:Myotonic dystrophy type 1 (DM1) is caused by large expansions of cytosine-thymine-guanine (CTG)-repeats in myotonic dystrophy protein kinase (DMPK)-gene. This gene is highly polymorphic in healthy individuals. It has been proposed that expanded alleles originated from the group of large sized normal alleles....

journal_title：Acta neurologica Scandinavica

authors： Culjković B,Stojković O,Vukosavić S,Savić D,Rakocevic V,Apostolski S,Romac S

更新日期：2002-01-01 00:00:00

abstract：:Multiple system atrophy (MSA) is a heterogeneous group of central neurological degenerations often associated with diffuse deterioration of the hypothalamic cholinergic neurons. In the hypothesis of an altered cholinergic regulation of vasopressin release, we evaluated vasopressin response to metoclopramide (20 mg i.v...

journal_title：Acta neurologica Scandinavica

authors： Norbiato G,Bevilacqua M,Righini V,Chebat E,Vago T,Bertora P,Castelli L,Mangoni A

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:To selectively investigate postganglionic sympathetic cardiac neurons in patients with Parkinson's disease and autonomic failure. MATERIAL AND METHODS:Metaiodobenzylguanidine (MIBG) is a pharmacologically inactive analogue of noradrenaline, which is similarly metabolized in noradrenergic neurons. Therefore t...

journal_title：Acta neurologica Scandinavica

authors： Braune S,Reinhardt M,Bathmann J,Krause T,Lehmann M,Lücking CH

更新日期：1998-05-01 00:00:00

abstract：:Ten patients with pseudotumor cerebri were studied. The diagnosis was based on bilateral papilledema and absence of intracranial masses and hydrocephalus. Based on the radiological findings, three groups of patients emerged: (A) Five patients with an empty sella. Four had an enlarged sella; (B) Two patients with a pit...

journal_title：Acta neurologica Scandinavica

authors： Bjerre P,Lindholm J,Gyldensted C

更新日期：1982-10-01 00:00:00

abstract：:In this study levels of neuron-specific enolase (NSE), S-100 protein (S-100) and myelin basic protein (MBP) in cerebrospinal fluid (CSF) of children and adults with distinct neurological disorders were examined. A previous study from our department demonstrated age related reference values for these brain-specific pro...

journal_title：Acta neurologica Scandinavica

authors： Lamers KJ,van Engelen BG,Gabreëls FJ,Hommes OR,Borm GF,Wevers RA

更新日期：1995-09-01 00:00:00

abstract：:A CSF Poly(C)-avid ribonuclease (RNase) activity was determined in serum and CSF of 11 controls and 75 neurological patients (34 multiple sclerosis (MS), 18 infectious processes and 23 other neurological diseases (OND]. In controls, the blood-CSF ratio of RNase activity is low. This fact and the absence of correlation...

journal_title：Acta neurologica Scandinavica

authors： Allinquant B,Musenger C,Schuller E

更新日期：1984-07-01 00:00:00

abstract：OBJECTIVE:To clarify how chronic solvent abuse affects cognitive function using magnetic resonance imaging as an index of brain damage. MATERIAL AND METHODS:A total of 25 chronic solvent abusers underwent magnetic resonance imaging with quantitative neurometry and Wechsler Adult Intelligence Scales revised. RESULTS:T...

journal_title：Acta neurologica Scandinavica

authors： Yamanouchi N,Okada S,Kodama K,Sakamoto T,Sekine H,Hirai S,Murakami A,Komatsu N,Sato T

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVES:Alzheimer's disease assessment scale-cognitive subscale (ADAS-Cog) has become a standard clinical trials outcome for cognition, but has been recognized as deficient in areas including coverage of cognitive domains, sensitivity and standardization. Computerized test batteries may address some of these issues....

journal_title：Acta neurologica Scandinavica

authors： Wesnes K,Edgar C,Andreasen N,Annas P,Basun H,Lannfelt L,Zetterberg H,Blennow K,Minthon L

更新日期：2010-10-01 00:00:00

abstract：:There is evidence from several laboratories of an increased prevalence of circulating immuno-complexes (CIC) in diabetic patients. It has also been suggested that CIC are pathogenetically related to chronic diabetic complications. The aim of this study was to assess peripheral nerve function in children with Type 1 di...

journal_title：Acta neurologica Scandinavica

authors： Fierro B,Modica A,Cardella F,Raimondo D,Triolo G,Meli F

更新日期：1991-03-01 00:00:00

abstract：:Treatment with intraventricular pentosan polysulphate (PPS) might be beneficial in patients with Creutzfeldt-Jakob disease. We report a 68-year-old woman with sporadic Creutzfeldt-Jakob disease who received continuous intraventricular PPS infusion (1-120 microg/kg/day) for 17 months starting 10 months after the onset ...

journal_title：Acta neurologica Scandinavica

authors： Terada T,Tsuboi Y,Obi T,Doh-ura K,Murayama S,Kitamoto T,Yamada T,Mizoguchi K

更新日期：2010-02-01 00:00:00

abstract：:Twenty-one patients continued a double-blind crossover study to compare the prophylactic effect on migraine of propranolol and clonidine. The daily dosage of propranolol and clonidine was 160 mg and 100 microgram, respectively. Statistical analysis did not show any significant difference between the two drugs in respe...

journal_title：Acta neurologica Scandinavica

authors： Kåss B,Nestvold K

更新日期：1980-06-01 00:00:00

abstract：:A total of 43 patients with multiple sclerosis (MS) consecutively admitted to the Multiple Sclerosis Rehabilitation Hospital in Haslev completed a Danish version of the Laman & Lankhorst Questionnaire (LLQ) on quality of life (qol), and the Beck Depression Inventory (BDI). Twenty-one of the 43 pts completed the questi...

journal_title：Acta neurologica Scandinavica

authors： Jønsson A,Dock J,Ravnborg MH

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:To assess hemispheric differences in the duration of focal onset seizures and its association with clinical and demographic factors. METHODS:A retrospective analysis was performed on adult patients with drug-resistant unifocal epilepsy, who underwent intracranial EEG recording between 01/2006 and 06/2016. Se...

journal_title：Acta neurologica Scandinavica

authors： Seethaler M,Lauseker M,Ernst K,Rémi J,Vollmar C,Noachtar S,Kaufmann E

更新日期：2020-10-04 00:00:00

abstract：:A young woman with firm evidence of early multiple sclerosis (MS), who had never had measles, developed a clinically and serologically evident measles infection. Follow-up 1 year later confirmed the MS diagnosis. Thus, if measles can have a causal role in MS, it is probably not the only agent with this ability. ...

journal_title：Acta neurologica Scandinavica

authors： Ryberg B

更新日期：1979-04-01 00:00:00

abstract：OBJECTIVES:Focal brain ischemia induced in rodents by occlusion of the middle cerebral artery (MCA) is a widely used paradigm of human brain infarct. The objective of this study is to compare the effectiveness and reproducibility of MCA filament occlusion model in rats and mice. MATERIALS AND METHODS:A total of 140 ro...

journal_title：Acta neurologica Scandinavica

authors： Ardehali MR,Rondouin G

更新日期：2003-04-01 00:00:00

abstract：:A purified citric acid soluble extract from human skeletal muscle (AEMA) and a phosphate-buffered saline extract from rabbit muscle acetone powder (EMA) were used to coat polystyrene beads in an enzyme-linked immunosorbent assay (ELISA). From 54 patients with myasthenia gravis, positive results were observed in 14. Fi...

journal_title：Acta neurologica Scandinavica

authors： Viana VS,Bueno C,Marchiori PE,Oliveira RM,Assis JL,Scaff M,Cossermelli W

更新日期：1986-06-01 00:00:00

abstract：:By a rapid PCR-based method to assess the 8344 mtDNA mutation associated with MERRF disease, we have studied DNA from blood samples of 10 individuals belonging to a family spanning four generations in which one patient showed the complete MERRF phenotype, three other members were less severely affected, while the rema...

journal_title：Acta neurologica Scandinavica

authors： Piccolo G,Focher F,Verri A,Spadari S,Banfi P,Gerosa E,Mazzarello P

更新日期：1993-12-01 00:00:00

abstract：:The occurrence of cerebral infarction in patients with transient global amnesia (n = 43) was evaluated by CT scan and compared to that of patients with transient ischemic attacks (TIA) (n = 58) and with no neurological disease (n = 52). Significant differences were demonstrated between TGA and TIA patients in relation...

journal_title：Acta neurologica Scandinavica

authors： Matias-Guiu J,Colomer R,Segura A,Codina A

更新日期：1986-03-01 00:00:00

abstract：:Nervous system involvement in patients with AIDS is frequent either due to direct infection by the HIV-1 or to opportunistic infections or neoplasms. In the present study we evaluate the epidemiologic characteristics of patients in whom the first AIDS manifestation was an indicative neurologic disease (IND) and the in...

journal_title：Acta neurologica Scandinavica

authors： Casabona J,Sánchez E,Graus F,Abós J,Segura A

更新日期：1991-07-01 00:00:00

abstract：OBJECTIVES:To evaluate the contribution of the demographical, clinical, analytical and genetic factors to brain signal intensity changes in T2-weighted MR images in amyotrophic lateral sclerosis (ALS) patients and controls. METHODS:Susceptibility-weighted and FLAIR sequences were obtained in a 3T MR scanner. Iron-rela...

journal_title：Acta neurologica Scandinavica

authors： Vázquez-Costa JF,Mazón M,Carreres-Polo J,Hervás D,Pérez-Tur J,Martí-Bonmatí L,Sevilla T

更新日期：2018-02-01 00:00:00

abstract：:Five patients with chronic progressive multiple sclerosis (MS) and three control patients with lumbar disc herniation were treated with dexamethazone during 14 days. The effect on peripheral blood T-cell subsets and on the proliferative response of peripheral blood mononuclear cells (PBMC) to pokeweed mitogen (PWM) an...

journal_title：Acta neurologica Scandinavica

authors： Salmaggi A,Baldetorp B,Milanese C,Nespolo A,Parma R,Sandberg-Wollheim M

更新日期：1991-08-01 00:00:00

abstract：:We report a case of a cystic lesion in the left cerebellopontine (CP) angle cistern. The magnetic resonance (MR) imaging features closely resembled an epidermoid inclusion cyst, and was interpreted as such. However, at surgery and on histopathological examination the lesion was found to be a cysticercus cyst. It may b...

journal_title：Acta neurologica Scandinavica

authors： Singh S,Gibikote SV,Bannur U,Chacko G,Korah IP,Rajshekhar V

更新日期：1999-04-01 00:00:00

abstract：:Twenty-four male patients, all homosexual except one, with asymptomatic HIV-infection were studied. The patients had no signs of opportunistic CNS-infections but 6 had been treated for syphilis. The patients were tested with auditory brainstem response (ABR) audiometry and with oculomotor tests (saccades and smooth pu...

journal_title：Acta neurologica Scandinavica

authors： Rosenhall U,Håkansson C,Löwhagen GB,Hanner P,Jonsson-Ehk B

更新日期：1989-02-01 00:00:00

abstract：OBJECTIVES:We used an electrical conditioning stimulation followed by transcranial magnetic stimulation (TMS) to facilitate the occurrence of long latency potentials (LLPs) in order to study the relationship between primary motor evoked potentials (MEPs) and LLPs in the lower limbs. MATERIALS AND METHODS:The study gro...

journal_title：Acta neurologica Scandinavica

authors： Chen JT,Chen CC,Kao KP,Wu ZA,Liao KK

更新日期：1998-12-01 00:00:00

abstract：:Paralytic poliomyelitis presenting with quadriparesis, transient encephalitis and bulbar symptoms in 2 patients in close contact with recently vaccinated children with trivalent live oral polio vaccine is described. Symmetrical lower motor neuron involvement of deltoid muscles with electromyographic confirmation was f...

journal_title：Acta neurologica Scandinavica

authors： Arlazoroff A,Bleicher Z,Klein C,Vure E,Lahat E,Gross B,Handsher R

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:Some recent studies have found an association between foetal malformations in earlier antiepileptic drug (AED)-exposed pregnancies and an increased hazard of such malformations in subsequent pregnancies. We investigated this matter further, and also considered the possible role of spontaneous abortions in pr...

journal_title：Acta neurologica Scandinavica

authors： Vajda FJ,O'Brien TJ,Graham JE,Hitchcock AA,Lander CM,Eadie MJ

更新日期：2017-03-01 00:00:00

abstract：:Demented patients with Alzheimer's disease (AD) (n = 67), multi-infarct dementia (MID) (n = 77) and probable vascular dementia (PVD) (n = 45) were studied with electroencephalography (EEG). All patients underwent a routine EEG examination and quantitative EEG was recorded from 14 patients with AD, 20 with MID, and 12 ...

journal_title：Acta neurologica Scandinavica

authors： Erkinjuntti T,Larsen T,Sulkava R,Ketonen L,Laaksonen R,Palo J

更新日期：1988-01-01 00:00:00

abstract：:The immediate effects of selective sympathetic and somatic blockades on pain and tactile allodynia in 12 patients with long-standing ophthalmic or high cervical postherpetic neuralgia were compared. For the duration of the somatic blockade, pain was completely abolished in 11 patients and allodynia in 8 patients. In c...

journal_title：Acta neurologica Scandinavica

authors： Nurmikko T,Wells C,Bowsher D

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVES:Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease. There is evidence that oxidative stress is implicated in the pathophysiology of the neurodegenerative disorders, including ALS. Data from the literature suggests that the receptor for advanced glycation end products (RAGE) partic...

journal_title：Acta neurologica Scandinavica

authors： Iłzecka J

更新日期：2009-08-01 00:00:00

abstract：:Carotid stenoses of ≥50% account for about 15-20% of strokes. Their degree may be moderate (50-69%) or severe (70-99%). Current diagnostic methods include ultrasound, MR- or CT-angiography. Stenosis severity, irregular plaque surface, and presence of microembolic signals detected by transcranial Doppler predict the ea...

journal_title：Acta neurologica Scandinavica

authors： Momjian-Mayor I,Burkhard P,Murith N,Mugnai D,Yilmaz H,Narata AP,Lovblad K,Pereira V,Righini M,Bounameaux H,Sztajzel RF

更新日期：2012-11-01 00:00:00