Less protease-resistant PrP in a patient with sporadic CJD treated with intraventricular pentosan polysulphate.

abstract：:In 100 MS patients, BAEP and tibial SEP abnormality rates increased significantly with disease duration and clinical disability. VEP correlated non-linearly with disease duration, and median nerve SEP correlated with disability. In multifactorial analysis, however, BAEP correlated significantly only with clinical brai...

journal_title：Acta neurologica Scandinavica

authors： Sand T,Sulg IA

更新日期：1990-09-01 00:00:00

abstract：OBJECTIVES:The pathophysiology of migraine headaches is not clearly understood yet. The dopaminergic system has been hypothesized to be involved in migraine pathogenesis. The aim of this study was to investigate catechol-O-methyltransferase (COMT) polymorphisms and chronic headaches. We analyzed five single nucleotide ...

journal_title：Acta neurologica Scandinavica

authors： Takigawa H,Kowa H,Nakashima K

更新日期：2017-02-01 00:00:00

abstract：:Forty-eight patients with a clinical diagnosis of Alzheimer's disease, 30 patients with cerebrovascular dementia, and 48 normal controls were assessed with a battery of neuropsychological tests designed to measure the following cognitive processes: orientation to time and place, memory, visual-perceptual and construct...

journal_title：Acta neurologica Scandinavica

authors： Villardita C

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral infarcts occur more frequently along the middle (MCA) than the anterior cerebral artery (ACA) territory. The reason(s) for this difference remains speculative. The objective of this study was to investigate the distribution of cerebral microemboli as detected by transcranial Doppler ultr...

journal_title：Acta neurologica Scandinavica

authors： Wijman CA,Babikian VL,Winter MR,Pochay VE

更新日期：2000-02-01 00:00:00

abstract：:The density and size of astrocyte-, oligodendrocyte-and neurone nuclei in corpus striatum were determined in rats with CCl4-induced liver encephalopathy by means of an electronic image analyzer. After 8 weeks of CCl4-administration, the astrocyte number had nearly doubled, and astrocytes with increased nuclear size qp...

journal_title：Acta neurologica Scandinavica

authors： Diemer NH

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune disorder of the central nervous system (CNS). Interleukin (IL)-6 and IL-17A may play important roles in the pathogenesis of this disease. High-mobility group box protein 1 (HMGB1), a small but highly conserved ubiquitous protein, is rec...

journal_title：Acta neurologica Scandinavica

authors： Ai P,Zhang X,Xie Z,Liu G,Liu X,Pan S,Wang H

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To explore the long-term effectiveness of rufinamide in managing Lennox-Gastaut Syndrome (LGS), other epileptic encephalopathies, and intractable focal epilepsies in adults and children in routine clinical practice. METHODS:A multicentre, retrospective chart review of patients prescribed adjunctive rufinamid...

journal_title：Acta neurologica Scandinavica

authors： Jaraba S,Santamarina E,Miró J,Toledo M,Molins A,Burcet J,Becerra JL,Raspall M,Pico G,Miravet E,Cano A,Fossas P,Fernández S,Falip M

更新日期：2017-01-01 00:00:00

abstract：:Cerebral angiography was carried out in two diabetic patients in the evaluation of minor vascular ischemic episodes. A transient acute renal failure following cerebral angiography was accompanied by a transient comatose episode with severe unilateral neurological deficits. A functional depression of the injected hemis...

journal_title：Acta neurologica Scandinavica

authors： Skyhøj Olsen T,Lund P,Praestholm J

更新日期：1981-12-01 00:00:00

abstract：:The results of intra-operative cortical EEG recordings (ECoG) were assessed in 30 patients with medically refractory complex partial seizures submitted to temporal lobectomy. Interictal spiking was most frequently recorded from mesial temporal lobe structures (amygdaloid-hippocampal region) and from the temporal neoco...

journal_title：Acta neurologica Scandinavica

authors： Stefan H,Quesney LF,Abou-Khalil B,Olivier A

更新日期：1991-02-01 00:00:00

abstract：:Serum immunoglobulin and HLA investigations were carried out in 21 probands with primary generalized corticoreticular epilepsy (PGCE) and in 26 of their first degree relatives. The mean serum levels of IgG, IgA and IgM in the epileptic probands were not significantly different from controls. In the relatives, however,...

journal_title：Acta neurologica Scandinavica

authors： Eeg-Olofsson O,Janjua NA,Andermann E,Guttmann RD,Osterland K

更新日期：1986-12-01 00:00:00

abstract：OBJECTIVE:To clarify how chronic solvent abuse affects cognitive function using magnetic resonance imaging as an index of brain damage. MATERIAL AND METHODS:A total of 25 chronic solvent abusers underwent magnetic resonance imaging with quantitative neurometry and Wechsler Adult Intelligence Scales revised. RESULTS:T...

journal_title：Acta neurologica Scandinavica

authors： Yamanouchi N,Okada S,Kodama K,Sakamoto T,Sekine H,Hirai S,Murakami A,Komatsu N,Sato T

更新日期：1997-07-01 00:00:00

abstract：:Paralytic poliomyelitis presenting with quadriparesis, transient encephalitis and bulbar symptoms in 2 patients in close contact with recently vaccinated children with trivalent live oral polio vaccine is described. Symmetrical lower motor neuron involvement of deltoid muscles with electromyographic confirmation was f...

journal_title：Acta neurologica Scandinavica

authors： Arlazoroff A,Bleicher Z,Klein C,Vure E,Lahat E,Gross B,Handsher R

更新日期：1987-09-01 00:00:00

abstract：:Two cases of adrenoleukodystrophy are described. The pathological picture was consistent with earlier observations about the disease with the difference that the brain tissue revealed material which stained metachromatically with toluidine blue and was insoluble in fat solvents. ...

journal_title：Acta neurologica Scandinavica

authors： Hormia M

更新日期：1978-08-01 00:00:00

abstract：INTRODUCTION:Charcot-Marie-Tooth disease (CMT) is a heterogeneous inherited neuropathy. The number of known CMT genes is rapidly increasing mainly due to next-generation sequencing technology, at present more than 70 CMT-associated genes are known. We investigated whether variants in the DCTN2 could cause CMT. MATERIA...

journal_title：Acta neurologica Scandinavica

authors： Braathen GJ,Høyer H,Busk ØL,Tveten K,Skjelbred CF,Russell MB

更新日期：2016-07-01 00:00:00

abstract：:Eleven patients with presenile Alzheimer type dementia (ATD) were treated with N-terminal ACTH fragments for 14 days. No change in cognitive functions was observed during the treatment. A significant increase in CSF beta-endorphin (beta-EP) levels was found, while ACTH and beta-lipoprotein remain unaffected. The possi...

journal_title：Acta neurologica Scandinavica

authors： Nappi G,Facchinetti F,Martignoni E,Petraglia F,Sinforiani E,Bono G,Genazzani AR

更新日期：1988-08-01 00:00:00

abstract：OBJECTIVES:The aim of this pilot study was to evaluate a psychological therapy program used in the treatment of multiple sclerosis (MS) and including cognitive/behavioral strategies, relaxation training and physical exercise. MATERIAL AND METHODS:The participants were 29 patients with MS recruited from an outpatient u...

journal_title：Acta neurologica Scandinavica

authors： Tesar N,Baumhackl U,Kopp M,Günther V

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVES:The prognosis after Lyme neuroborreliosis (LNB) is debated. The aim of this study was to assess health-related Quality of Life (QoL) and neurological symptoms 30 months after treatment in European patients with LNB. MATERIALS AND METHODS:In a prospective case-control designed study, we investigated 50 well-...

journal_title：Acta neurologica Scandinavica

authors： Eikeland R,Mygland A,Herlofson K,Ljøstad U

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Persons with multiple sclerosis (MS) engage in substantially less overall physical activity than healthy controls, but there is little information on public health rates of physical activity necessary for health benefits. PURPOSE:This study examined the rates of insufficient, moderate, and sufficient physic...

journal_title：Acta neurologica Scandinavica

authors： Motl RW,McAuley E,Sandroff BM,Hubbard EA

更新日期：2015-06-01 00:00:00

abstract：:The composition of the free amino acid pools in various brain tumors and in normal brains obtained at surgery or at autopsy is determined with an automatic amino acid analyzer and the results statistically evaluated. The tumors have lower ratios of GABA in the pools than the normal brain; tumors with higher GABA ratio...

journal_title：Acta neurologica Scandinavica

authors： Shibasaki T,Uki J,Kanoh T,Kawafuchi J

更新日期：1979-01-01 00:00:00

abstract：:In a double-blind crossover pilot study with placebo, choline chloride, the physiologic precursor of acetylcholine, was tested in six patients with cerebellar ataxia. Neither subjectively nor objectively could any statistical significant difference be demonstrated. ...

journal_title：Acta neurologica Scandinavica

authors： Sehested P,Lund HI,Kristensen O

更新日期：1980-08-01 00:00:00

abstract：OBJECTIVES:Comprehensive epidemiologic data for multiple sclerosis (MS) in Spain are limited. The aim of this study was to collect epidemiologic data on MS in the Northern Seville District of Spain. MATERIALS AND METHODS:This longitudinal study identified possible MS cases every year from nine centres between 1 Januar...

journal_title：Acta neurologica Scandinavica

authors： Izquierdo G,Venegas A,Sanabria C,Navarro G

更新日期：2015-08-01 00:00:00

abstract：:In a well-defined prospective series of 247 patients with a first-ever supratentorial brain infarct, 15 patients (6%; 95% confidence interval 3-9%) had a large striatocapsular infarct. Twelve (80%) had signs of cortical dysfunction, whereas risk factor profile, frequency of significant carotid stenosis, and frequency ...

journal_title：Acta neurologica Scandinavica

authors： Boiten J,Lodder J

更新日期：1992-09-01 00:00:00

abstract：OBJECTIVES:We evaluated the expression of chemokine-like factor (CKLF) in biopsied muscle fibers in inflammatory myopathies, non-inflammatory myopathies and neurologically diseased controls. MATERIALS AND METHODS:We studied the expression of CKLF in 15 polymyositis (PM), five dermatomyositis (DM), 15 non-inflammatory ...

journal_title：Acta neurologica Scandinavica

authors： Chowdhury MH,Nagai A,Terashima M,Sheikh A,Murakawa Y,Kobayashi S,Yamaguchi S

更新日期：2008-08-01 00:00:00

abstract：:Bulbar dysfunction resulting from corticobulbar pathway or brainstem neuron degeneration is one of the most important clinical problems encountered in motor neuron disease (MND) and contributes to various respiratory complications which are major causes of morbidity and mortality. Chronic malnutrition as a consequence...

journal_title：Acta neurologica Scandinavica

authors： Hadjikoutis S,Wiles CM

更新日期：2001-04-01 00:00:00

abstract：:The influence of the rheological properties of the blood on cerebral perfusion is still unresolved. Data on normal subjects are lacking and difficulties arise regarding the effect of blood viscosity owing to its close relationship with hematocrit. For these reasons we have studied the relationship between two rheologi...

journal_title：Acta neurologica Scandinavica

authors： Cavestri R,Radice L,Ferrarini F,Longhini M,Longhini E

更新日期：1992-04-01 00:00:00

abstract：:The concentrations of sulfur-containing amino acids (taurine, methionine, cystine, cystathionine, homocystine) in lumbar CSF from patients with consciousness disturbances and controls were measured, and it was investigated whether there was any correlation between the sequential changes of these amino acid concentrati...

journal_title：Acta neurologica Scandinavica

authors： Yanai Y,Shibasaki T,Kohno N,Mitsui T,Nakajima H

更新日期：1983-12-01 00:00:00

abstract：OBJECTIVES:Myotonic dystrophy type 1 (DM1) is caused by large expansions of cytosine-thymine-guanine (CTG)-repeats in myotonic dystrophy protein kinase (DMPK)-gene. This gene is highly polymorphic in healthy individuals. It has been proposed that expanded alleles originated from the group of large sized normal alleles....

journal_title：Acta neurologica Scandinavica

authors： Culjković B,Stojković O,Vukosavić S,Savić D,Rakocevic V,Apostolski S,Romac S

更新日期：2002-01-01 00:00:00

abstract：:A three generation family is presented in which rapidly progressive, early-onset Creutzfeldt-Jakob disease without typical EEG changes segregates as an autosomal dominant disease. An aspartic acid to asparagine mutation at codon 178 of the prion gene, PRNP, co-segregates with the disease. As expected, the disease alle...

journal_title：Acta neurologica Scandinavica

authors： Holm IE,Abelskov K,Bojsen-Møller M,Nielsen AL,Jørgensen AL

更新日期：2001-03-01 00:00:00

abstract：:A 23-year-old patient suffering from mental deterioration was referred for CT study following her first epileptic fit. The study disclosed generalized atrophy and diffuse symmetric white matter hypodensities. Similar findings were found in her 13-year-old retarded sister. The diagnosis of metachromatic leukodystrophy ...

journal_title：Acta neurologica Scandinavica

authors： Reider-Grosswasser I,Bornstein N

更新日期：1987-01-01 00:00:00

abstract：:Beta-2-microglobulin (beta 2m) levels were studied in the cerebrospinal fluid (CSF) and plasma of 52 patients with clinically definite multiple sclerosis (MS) and of 14 with aseptic meningo-encephalitis (AM). Reference values for beta 2m were defined in 72 subjects of different age groups with tension headache (TH). P...

journal_title：Acta neurologica Scandinavica

authors： Us O,Lolli F,Baig S,Link H

更新日期：1989-12-01 00:00:00