CT and MRI in late-onset metachromatic leukodystrophy.

abstract：:Cognitive deficits have been reported in 45%-70% of patients with multiple sclerosis (MS). Like other symptoms of MS, cognitive deficits are highly variable. Slowed information processing and memory and learning dysfunction are regarded as the most frequent cognitive deficits in MS. Both white and gray matter damages ...

journal_title：Acta neurologica Scandinavica

authors： Hämäläinen P,Rosti-Otajärvi E

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Paraneoplastic neurological syndromes (PNS) are rare remote effect of cancer. The antibodies and tumors associated with PNS have been well described, but there are still many clinically suspected cases in which no tumor or antibody can be identified. This is the first report of PNS showing hot cross-bun sign...

journal_title：Acta neurologica Scandinavica

authors： Ishikawa H,Kawada N,Taniguchi A,Odachi K,Mizutani A,Asahi M,Tomimoto H

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:Biomarkers with the potential for longitudinal measurements are needed in multiple sclerosis (MS). Urine is easy to collect, and repeated sampling is possible. METHODS:39 paired CSF and urine samples were taken. Oligoclonal bands (OCBs) were measured in CSF. Kappa and lambda free light chain (FLC), neopteri...

journal_title：Acta neurologica Scandinavica

authors： Dobson R,Topping J,Davis A,Thompson E,Giovannoni G

更新日期：2013-11-01 00:00:00

abstract：:Factors at presentation which influenced the course of the disease and response to treatment were assessed in 125 de novo patients with Parkinson's disease. Ninety-eight patients were available for re-assessment at 5 years. Older patients presented earlier after the onset of symptoms, deteriorated more rapidly, and we...

journal_title：Acta neurologica Scandinavica

authors： Hely MA,Morris JG,Reid WG,O'Sullivan DJ,Williamson PM,Broe GA,Adena MA

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVES:To measure gait and postural stability by objective methods in spastic MS patients and to evaluate the effect of baclofen on gait and postural stability. PATIENTS AND METHODS:Fourteen spastic MS patients were examined in a placebo controlled double-blind, cross-over trial of oral baclofen treatment. The gai...

journal_title：Acta neurologica Scandinavica

authors： Orsnes GB,Sørensen PS,Larsen TK,Ravnborg M

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVES:The goal of this study was to evaluate the incidence of urological malignancies in MS patients using active screening. MATERIAL AND METHODS:A total of 495 MS patients (141 men, 354 women, age of 42±13.4) were included in the study. The duration of disease was 12.3±11 years, and the EDSS score was 4.3 (±2.5)...

journal_title：Acta neurologica Scandinavica

authors： Krhut J,Hradilek P,Nemec D,Tvrdik J,Zapletalova O,Zvara P

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:Dopamine neurotransmission is a critical factor for executive function, which is controlled by the prefrontal cortex in humans. Although the contribution of genetic factors to the regulation of brain dopaminergic activity is widely acknowledged, identification of a genotype-phenotype association has not yet ...

journal_title：Acta neurologica Scandinavica

authors： Mitaki S,Isomura M,Maniwa K,Yamasaki M,Nagai A,Nabika T,Yamaguchi S

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:Epstein-Barr virus (EBV) infection is associated with multiple sclerosis (MS), and EBV may transform lymphoblastoid cell lines more frequently in MS patients than controls, but it is not clear whether this reflects a higher viral load or an enhanced ability to reactivate EBV. MATERIAL AND METHODS:MS patient...

journal_title：Acta neurologica Scandinavica

authors： Tørring C,Andreasen C,Gehr N,Bjerg L,Petersen T,Höllsberg P

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVES:To estimate dementia prevalence in Spain. MATERIALS AND METHODS:Nine probabilistic and geographically defined samples participated. A screening design based on the MMSE was implemented. Positively screened individuals underwent clinical evaluation. The total number of cases in Spain was estimated. Prevalenc...

journal_title：Acta neurologica Scandinavica

authors： Virués-Ortega J,de Pedro-Cuesta J,Vega S,Seijo-Martínez M,Saz P,Rodríguez F,Rodríguez-Laso A,Reñé R,de Las Heras SP,Mateos R,Martínez-Martín P,Mahillo-Fernández I,López-Pousa S,Lobo A,Reglà JL,Gascón J,García FJ,Fernánd

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVES:A confident and accurate diagnosis of multiple sclerosis (MS) is important, but a specific diagnostic test for the disease does not exist. The traditional diagnostic criteria of Poser et al. were published in 1983, and recently, McDonald et al. recommended new criteria for the diagnosis of MS. PATIENTS AND ...

journal_title：Acta neurologica Scandinavica

authors： Fangerau T,Schimrigk S,Haupts M,Kaeder M,Ahle G,Brune N,Klinkenberg K,Kotterba S,Möhring M,Sindern E,Multiple Sclerosis Study Group.

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVES:To estimate the need for and the costs of carotid Doppler and carotid endarterectomy after stroke or TIA in non-selected hospitalized patients. MATERIAL AND METHODS:During 25 months hospitalized patients with stroke or TIA, in whom carotid endarterectomy could be relevant, were examined with carotid Doppler...

journal_title：Acta neurologica Scandinavica

authors： Jespersen HF,Jørgensen HS,Nakayama H,Reith J,Olsen TS

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To describe spinal epidural abscess after treatment with rituximab. METHODS:Report of a new case of cervical epidural spinal abscess after treatment with rituximab and review of the literature. RESULTS:Biologic agents are associated with an increased risk of serious infections, there are only few reports of...

journal_title：Acta neurologica Scandinavica

authors： Avila JD,Živković S

更新日期：2016-05-01 00:00:00

abstract：:In order to approach the mechanism of chronic or relapsing course in human chronic inflammatory demyelinating polyradiculoneuropathy, we established a chronic model of experimental allergic neuritis (EAN) in juvenile guinea pigs, and investigated the underlying cellular immune phenomenon in comparison with acute EAN i...

journal_title：Acta neurologica Scandinavica

authors： Suzumura A,Sobue G,Sugimura K,Matsuoka Y,Sobue I

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVES:When the vascular disorder of the cochleovestibular system is mentioned, the diagnosis is based on exclusion of other diseases. Since arteries of the cochleovestibular system cannot be directly visualized, physicians must deduce from the vascular risk factors and the vascular lesion of other territories to t...

journal_title：Acta neurologica Scandinavica

authors： Szirmai A,Küstel M,Pánczél G,Kocher I,Répássy G,Nagy Z

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVES:Health-related quality of life (HRQL) has become an important outcome criterion of medical interventions, but was hardly studied in patients with facial spasms. MATERIALS AND METHODS:Patients with blepharospasm or hemifacial spasm treated with botulinum toxin were included. A healthy control group sociodemo...

journal_title：Acta neurologica Scandinavica

authors： Reimer J,Gilg K,Karow A,Esser J,Franke GH

更新日期：2005-01-01 00:00:00

abstract：:A case of necrotizing brain stem encephalitis due to listeria monocytogenes is described in a 48-year-old man who had brain stem encephalitis of complicated course and with selective destruction of the vasomotoric and respiratory centers. He developed that very rare Ondine's curse syndrome, being only able to breathe ...

journal_title：Acta neurologica Scandinavica

authors： Jensen TH,Hansen PB,Brodersen P

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:Variants in genes encoding enzymes involved in production, aggregation or degradation of beta-amyloid are potential risk factors for sporadic Alzheimer's disease (AD). METHODS:Meta-analyses on AD association with BACE1 exon 5, BACE1 intron 5, FE65 intron 13, CYP46 intron 2, alpha(1)-antichymotrypsine Ala17T...

journal_title：Acta neurologica Scandinavica

authors： Llorca J,Rodríguez-Rodríguez E,Dierssen-Sotos T,Delgado-Rodríguez M,Berciano J,Combarros O

更新日期：2008-01-01 00:00:00

abstract：:Serum immunoglobulin and HLA investigations were carried out in 21 probands with primary generalized corticoreticular epilepsy (PGCE) and in 26 of their first degree relatives. The mean serum levels of IgG, IgA and IgM in the epileptic probands were not significantly different from controls. In the relatives, however,...

journal_title：Acta neurologica Scandinavica

authors： Eeg-Olofsson O,Janjua NA,Andermann E,Guttmann RD,Osterland K

更新日期：1986-12-01 00:00:00

abstract：MATERIALS AND METHODS:In a prospective study we evaluated patients with first generalized tonic-clonic seizure (GTCS) (n = 16, age: 31 +/- 11 years, 8 women) and patients with vaso-vagal syncope (VVS) (n = 17, age: 32 +/- 13 years, 8 women), diagnosed on the basis of past history and clinical presentation who had serum...

journal_title：Acta neurologica Scandinavica

authors： Neufeld MY,Treves TA,Chistik V,Korczyn AD

更新日期：1997-03-01 00:00:00

abstract：:Psychometric tests, visual reaction time tests and electroencephalograms were performed in 26 cirrhotic patients without overt portal-systemic encephalopathy and in 26 healthy individuals. Cirrhotics performed poorly, compared with controls, on intelligence, learning and memory, perceptual motor and spatial tests. Non...

journal_title：Acta neurologica Scandinavica

authors： Puca FM,Antonaci F,Panella C,Guglielmi FW,Barone M,Francavilla A,Cerutti R

更新日期：1989-04-01 00:00:00

abstract：:Alterations in nervous system functioning following acute and chronic ethanol exposure have been studied in a great number of experimental investigations. Results from many of these investigations can be difficult to interpret, particularly since a variety of techniques and exposure models are employed. This review em...

journal_title：Acta neurologica Scandinavica

authors： Melgaard B

更新日期：1983-03-01 00:00:00

abstract：:Patients with multiple sclerosis have an increased risk of infections compared to the general population. The increased risk has been described for decades and is not alone attributed to the use of disease-modifying drugs, but secondary to the disability. The introduction of more potent immunomodulatory drugs may caus...

journal_title：Acta neurologica Scandinavica

authors： Celius EG

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:We propose that the increase in TNF-alpha and IL-6 in the brain in idiopathic parkinsonism is in response to a peripheral immune/ inflammatory process, so ubiquitous as to be responsible for the resemblance between ageing and parkinsonism. METHODS:Circulating cytokine was measured in 78 subjects with idio...

journal_title：Acta neurologica Scandinavica

authors： Dobbs RJ,Charlett A,Purkiss AG,Dobbs SM,Weller C,Peterson DW

更新日期：1999-07-01 00:00:00

abstract：UNLABELLED:FUNDAMENTALS AND OBJECTIVE: Multiple sclerosis (MS) is the prototype of demyelinating disease, but recently, it has been shown that the existence of axonal lesions contribute to irreversible central nervous system damage in this disease. Tau proteins are considered to be important for maintaining the stabili...

journal_title：Acta neurologica Scandinavica

authors： Jiménez-Jiménez FJ,Zurdo JM,Hernanz A,Medina-Acebrón S,de Bustos F,Barcenilla B,Sayed Y,Ayuso-Peralta L

更新日期：2002-12-01 00:00:00

abstract：:A group of asymptomatic HIV-infected patients (CDC II and III) was followed-up over a two year period with semi-annual neuropsychological testing. Of the total sample of 36 subjects, all were retested at test two (T2), 19 at test three (T3) and 13 at test four (T4). A subgroup of subjects was further tested on a simpl...

journal_title：Acta neurologica Scandinavica

authors： Karlsen NR,Reinvang I,Frøland SS

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:The Multiple Sclerosis Functional Composite (MSFC) is a multidimensional measurement tool for multiple sclerosis (MS) including a measure of ambulation (Timed 25-foot Walk [TWT]), arm function (Nine-Hole Peg Test [9HPT]) and cognition (Paced Auditory Serial Addition Test [PASAT]). OBJECTIVES:To assess the r...

journal_title：Acta neurologica Scandinavica

authors： Rosti-Otajärvi E,Hämäläinen P,Koivisto K,Hokkanen L

更新日期：2008-06-01 00:00:00

abstract：:Brivaracetam (BRV) is a new antiseizure medication (ASM) that is currently approved for adjunctive treatment in patients with focal onset seizures. Similarly to levetiracetam (LEV), BRV works by binding SV2A vesicles with a high affinity and a linear pharmacokinetic profile. Retrospective studies and randomized clinic...

journal_title：Acta neurologica Scandinavica

authors： Verrotti A,Grasso EA,Cacciatore M,Matricardi S,Striano P

更新日期：2020-09-23 00:00:00

abstract：:The intrathecal production (ITP) of the immunoglobulins (Ig) G, A, M and D was examined in untreated patients with multiple sclerosis (MS) and controls. Sensitive sandwich enzyme-linked immunosorbent assay systems were applied to the determination of IgA, IgM and IgD levels in the cerebrospinal fluid and plasma from a...

journal_title：Acta neurologica Scandinavica

authors： Lolli F,Halawa I,Link H

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVES:To analyze the correlation between blood pressure (BP) variability and leukoaraiosis (LA) amount in patients with symptomatic cerebral small-vessel disease. MATERIALS AND METHODS:We included 25 hypertensive patients: 13 with Binswanger's disease (BD) and 12 with a first-ever lacunar infarction (LI). Baselin...

journal_title：Acta neurologica Scandinavica

authors： Martí-Fàbregas J,Valencia C,Pujol J,García-Sánchez C,Roca-Cusachs A,López-Contreras J,Solé MJ,Martí-Vilalta JL

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:To study migraine without aura (MwoA) prevalence in the commune of Vågå, Norway; 1838 (18- to 65-year-old) individuals were included. A special search was made for cervicogenic characteristics in MwoA, as it has been claimed that such characteristics may frequently be present. A comparison with cervicogenic ...

journal_title：Acta neurologica Scandinavica

authors： Sjaastad O,Bakketeig LS

更新日期：2008-06-01 00:00:00