Spinal epidural abscess following treatment with rituximab.

Abstract:

OBJECTIVE:To describe spinal epidural abscess after treatment with rituximab. METHODS:Report of a new case of cervical epidural spinal abscess after treatment with rituximab and review of the literature. RESULTS:Biologic agents are associated with an increased risk of serious infections, there are only few reports of spinal epidural abscesses following immunomodulatory treatment with biologic agents, including only one other case of an epidural abscess after the use of rituximab. The risk may be greater with the use of other immunosuppressive medications, or with combined immunotherapy. CONCLUSION:Spinal epidural abscess is a rare complication with potential severe morbidity, and continued vigilance is needed as timely intervention may prevent severe morbidity and potentially fatal outcome.

journal_name

Acta Neurol Scand

authors

Avila JD,Živković S

doi

10.1111/ane.12506

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

403-5

issue

5

eissn

0001-6314

issn

1600-0404

journal_volume

133

pub_type

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