Restless legs syndrome: an early manifestation of Huntington's disease?

abstract：:Anti-muscle-specific receptor tyrosine kinase (MuSK) antibody-positive myasthenia gravis (MG) patients show various responses to conventional immunosuppressive treatment and some patients are resistant to these therapies. We report a 50-year-old Japanese man with anti-MuSK antibody-positive MG, who showed no or poor r...

journal_title：Acta neurologica Scandinavica

authors： Shibata-Hamaguchi A,Samuraki M,Furui E,Iwasa K,Yoshikawa H,Hayashi S,Yamada M

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVES:Alzheimer's disease assessment scale-cognitive subscale (ADAS-Cog) has become a standard clinical trials outcome for cognition, but has been recognized as deficient in areas including coverage of cognitive domains, sensitivity and standardization. Computerized test batteries may address some of these issues....

journal_title：Acta neurologica Scandinavica

authors： Wesnes K,Edgar C,Andreasen N,Annas P,Basun H,Lannfelt L,Zetterberg H,Blennow K,Minthon L

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine whether reactivation of Epstein-Barr (EBV) or activation of the anti-EBV immune response correlates with MS disease activity on MR imaging. METHODS:Subjects with early, active relapsing-remitting MS were studied for 16 weeks with blood and saliva samples collected...

journal_title：Acta neurologica Scandinavica

authors： Latham LB,Lee MJ,Lincoln JA,Ji N,Forsthuber TG,Lindsey JW

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:To estimate dementia prevalence in Spain. MATERIALS AND METHODS:Nine probabilistic and geographically defined samples participated. A screening design based on the MMSE was implemented. Positively screened individuals underwent clinical evaluation. The total number of cases in Spain was estimated. Prevalenc...

journal_title：Acta neurologica Scandinavica

authors： Virués-Ortega J,de Pedro-Cuesta J,Vega S,Seijo-Martínez M,Saz P,Rodríguez F,Rodríguez-Laso A,Reñé R,de Las Heras SP,Mateos R,Martínez-Martín P,Mahillo-Fernández I,López-Pousa S,Lobo A,Reglà JL,Gascón J,García FJ,Fernánd

更新日期：2011-05-01 00:00:00

abstract：:Experimental alcoholic myopathy was induced in rats by a combination of prolonged alcohol intake (mean 15.3 g ethanol/kg/day for up to 10 weeks) and a short fast. In view of literature evidence for impairment of both glycolytic and oxidative metabolism in alcoholic myopathy, we combined histological and histochemical ...

journal_title：Acta neurologica Scandinavica

authors： Trounce I,Byrne E,Dennett X

更新日期：1990-12-01 00:00:00

abstract：:Patients with homocystinuria excrete a large amount of metal in their urine. Homocysteine similar to penicillamine, administration to methylmercury treated rats resulted in a large amount of urinary methylmercury excretion. These results suggested that the total metal amounts in the whole body of patients with homocys...

journal_title：Acta neurologica Scandinavica

authors： Yoshida Y,Nakano A,Hamada R,Kamitsuchibashi H,Yamamoto K,Akagi H,Kitazono M,Osame M

更新日期：1992-11-01 00:00:00

abstract：:Serum and CSF from 53 vascular dementia (VD) patients and 50 controls were analysed to investigate the possibility of an intrathecal synthesis of IgG, defined as an elevated IgG index (greater than or equal to 7) and/or presence of oligoclonal IgG in cerebrospinal fluid (CSF), but not in serum. Five (9%) patients and ...

journal_title：Acta neurologica Scandinavica

authors： Wallin A,Blennow K,Fredman P,Gottfries CG,Karlsson I,Svennerholm L

更新日期：1990-02-01 00:00:00

abstract：OBJECTIVES:To describe the influence of the site of the bleeding on clinical spectrum and early outcome of patients with acute spontaneous intracerebral hemorrhage (ICH). MATERIALS AND METHODS:ICH was diagnosed in 229 (11%) of 2000 consecutive stroke patients included in a prospective stroke registry over a 10-year pe...

journal_title：Acta neurologica Scandinavica

authors： Arboix A,Comes E,García-Eroles L,Massons J,Oliveres M,Balcells M,Targa C

更新日期：2002-04-01 00:00:00

abstract：:The etiological characteristics of cerebrovascular disease (CVD) before the age of 55 are reviewed in 399 patients admitted to the Department of Neurology, Karolinska Hospital, Stockholm, from 1973-77. The material was well-defined with regard to subtypes of stroke as well as to the diseased population. The control ma...

journal_title：Acta neurologica Scandinavica

authors： Mettinger KL,Söderström CE,Neiman J

更新日期：1984-12-01 00:00:00

abstract：OBJECTIVES:Biomarkers with the potential for longitudinal measurements are needed in multiple sclerosis (MS). Urine is easy to collect, and repeated sampling is possible. METHODS:39 paired CSF and urine samples were taken. Oligoclonal bands (OCBs) were measured in CSF. Kappa and lambda free light chain (FLC), neopteri...

journal_title：Acta neurologica Scandinavica

authors： Dobson R,Topping J,Davis A,Thompson E,Giovannoni G

更新日期：2013-11-01 00:00:00

abstract：:We describe eight patients from three families presenting with myoclonus, ataxia, infrequent seizures and minimal intellectual impairment. All were Arabs from different parts of the Arabian peninsula. The new consensus on terminology, genetic and clinical definition of Baltic myoclonus, Ramsay Hunt syndrome and Unverr...

journal_title：Acta neurologica Scandinavica

authors： Shakir RA,Khan RA,al-Zuhair AG

更新日期：1992-11-01 00:00:00

abstract：:With the macrophage electrophoretic mobility (MEM) test of Field & Caspary, lymphocyte sensitization to thyroid antigen (F1-fraction) is demonstrable in all subjects--multiple sclerosis (MS) patients, those with other (destructive) neurological diseases (OND) and normals. The MEM-LAD test enables a further differentia...

journal_title：Acta neurologica Scandinavica

authors： Jenssen HL,Meyer-Rienecker HJ,Köhler H,Günther JK

更新日期：1976-01-01 00:00:00

abstract：OBJECTIVES:We evaluated the expression of chemokine-like factor (CKLF) in biopsied muscle fibers in inflammatory myopathies, non-inflammatory myopathies and neurologically diseased controls. MATERIALS AND METHODS:We studied the expression of CKLF in 15 polymyositis (PM), five dermatomyositis (DM), 15 non-inflammatory ...

journal_title：Acta neurologica Scandinavica

authors： Chowdhury MH,Nagai A,Terashima M,Sheikh A,Murakawa Y,Kobayashi S,Yamaguchi S

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:Assessment of usefulness of magnetoencephalography (MEG) as a novel non-invasive technique in the diagnostic evaluation of patients with recurrent seizures after unsuccessful epilepsy surgery. MATERIAL AND METHODS:Seventeen patients in whom epilepsy surgery had failed underwent reevaluation by means of MEG i...

journal_title：Acta neurologica Scandinavica

authors： Kirchberger K,Hummel C,Stefan H

更新日期：1998-07-01 00:00:00

abstract：:Neuropsychiatric symptoms such as delusions and misidentifications have been reported in dementia ranging from 10% to 73% in Alzheimer's disease (AD) patients and up to 40% in multi-infarct dementia (MID) patients. The aim of this study was to investigate in 61 AD and 31 MID patients both the frequency and the content...

journal_title：Acta neurologica Scandinavica

authors： Binetti G,Bianchetti A,Padovani A,Lenzi G,De Leo D,Trabucchi M

更新日期：1993-07-01 00:00:00

abstract：:Patients with prior poliomyelitis with paresis and excessive use (n = 8) and low use (n = 6) of residual anterior tibial motor units (MUs) during walking were subjected to muscle biopsy of the anterior tibial muscle (TA). Antibodies directed against cytoskeletal proteins, spectrin and desmin, and against Leu-19, a myo...

journal_title：Acta neurologica Scandinavica

authors： Borg K,Edström L

更新日期：1993-02-01 00:00:00

abstract：:Electromyograms (EMGs) are usually considered artifacts during electroencephalographic (EEG) recording for determination of electrocerebral silence (ECS). Appearance of scalp motor unit activity, however, may reflect residual brainstem function and can introduce difficulty in establishing a secure diagnosis of brain d...

journal_title：Acta neurologica Scandinavica

authors： Wee AS

更新日期：1986-08-01 00:00:00

abstract：:Multiple system atrophy (MSA) is a heterogeneous group of central neurological degenerations often associated with diffuse deterioration of the hypothalamic cholinergic neurons. In the hypothesis of an altered cholinergic regulation of vasopressin release, we evaluated vasopressin response to metoclopramide (20 mg i.v...

journal_title：Acta neurologica Scandinavica

authors： Norbiato G,Bevilacqua M,Righini V,Chebat E,Vago T,Bertora P,Castelli L,Mangoni A

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:For patients with medication refractory medial temporal lobe epilepsy (MTLE), surgery offers the hope of a cure. However, up to 30% of patients with MTLE continue to experience disabling seizures after surgery. The reasons why some patients do not achieve seizure freedom are poorly understood. A promising the...

journal_title：Acta neurologica Scandinavica

authors： Breedlove J,Nesland T,Vandergrift WA 3rd,Betting LE,Bonilha L

更新日期：2014-08-01 00:00:00

abstract：:A family with coincidence of a restless leg syndrome (RLS) in the mother and a Gilles de la Tourette syndrome (GTS) in the son who also shows increased vulnerability to neuroleptic induced akathisia (NIA) is presented. Since these diseases show parallels from a genetic, pathogenetic and clinical point of view, the fam...

journal_title：Acta neurologica Scandinavica

authors： Müller N,Voderholzer U,Kurtz G,Straube A

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Post-stroke cognitive impairment (PSCI) occurs commonly and is linked with development of dementia. We investigated the relationship between demographic, clinical and stroke symptoms at stroke onset and the presence of PSCI at 1 and 3 years after stroke. METHODS:We accessed anonymized data from the Virtual ...

journal_title：Acta neurologica Scandinavica

authors： Arba F,Quinn T,Hankey GJ,Inzitari D,Ali M,Lees KR,VISTA Collaboration.

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the role of transesophageal echocardiography in detecting the source of cerebral embolism in ischemic stroke patients and to evaluate the difference in occurrence of heart abnormalities in anterior and posterior circulation infarcts. MATERIAL AND METHODS:The study group i...

journal_title：Acta neurologica Scandinavica

authors： Mendel T,Pasierski T,Szwed H,Barańska-Gieruszczak M,Członkowska A

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Both pregnancy and high vitamin D concentration seem to generate a protective environment against multiple sclerosis (MS) relapses. Longitudinal case-control analysis of vitamin D concentrations during pregnancy and lactation of MS mothers is lacking. AIMS OF THE STUDY:To examine serum 25-hydroxyvitamin-D3 ...

journal_title：Acta neurologica Scandinavica

authors： Jalkanen A,Kauko T,Turpeinen U,Hämäläinen E,Airas L

更新日期：2015-01-01 00:00:00

abstract：:Brain perfusion was studied interictally with 99mTc-HM-PAO SPECT in 47 adult patients with partial epilepsy and normal brain CT. Epilepsy was classified as secondarily generalized in 24 patients, as complex partial in 17 patients and as simple partial in 6 patients. In 24 patients good seizure control was not achieved...

journal_title：Acta neurologica Scandinavica

authors： Launes J,Iivanainen M,Salmi T,Nikkinen P,Lindroth L,Liewendahl K

更新日期：1992-12-01 00:00:00

abstract：:Muscle cramps are involuntary, painful, sudden contractions of the skeletal muscles. They are present in normal subjects under certain conditions (during a strong voluntary contraction, sleep, sports, pregnancy) and in several pathologies such as myopathies, neuropathies, motoneuron diseases, metabolic disorders, hydr...

journal_title：Acta neurologica Scandinavica

authors： Parisi L,Pierelli F,Amabile G,Valente G,Calandriello E,Fattapposta F,Rossi P,Serrao M

更新日期：2003-03-01 00:00:00

abstract：:Twenty-four male patients, all homosexual except one, with asymptomatic HIV-infection were studied. The patients had no signs of opportunistic CNS-infections but 6 had been treated for syphilis. The patients were tested with auditory brainstem response (ABR) audiometry and with oculomotor tests (saccades and smooth pu...

journal_title：Acta neurologica Scandinavica

authors： Rosenhall U,Håkansson C,Löwhagen GB,Hanner P,Jonsson-Ehk B

更新日期：1989-02-01 00:00:00

abstract：OBJECTIVES:To determine if visual hallucinations in patients with Parkinson's disease are associated with an increased prevalence of white matter lesions. PATIENTS AND METHODS:Fifteen patients with (group 1) and 15 patients without (group 2) a history of visual hallucinations were studied. Both groups were matched for...

journal_title：Acta neurologica Scandinavica

authors： Kraft E,Winkelmann J,Trenkwalder C,Auer DP

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:The Multiple Sclerosis Functional Composite (MSFC) is a multidimensional measurement tool for multiple sclerosis (MS) including a measure of ambulation (Timed 25-foot Walk [TWT]), arm function (Nine-Hole Peg Test [9HPT]) and cognition (Paced Auditory Serial Addition Test [PASAT]). OBJECTIVES:To assess the r...

journal_title：Acta neurologica Scandinavica

authors： Rosti-Otajärvi E,Hämäläinen P,Koivisto K,Hokkanen L

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:In this follow-up study, we wanted to present the long-term outcome (5-21 years) in terms of seizure freedom, seizure reduction, and the cognitive development in the first 47 children who underwent epilepsy surgery at the University Hospital in Lund from 1991 to 2007. MATERIALS AND METHODS:All children who ...

journal_title：Acta neurologica Scandinavica

authors： Hallböök T,Tideman P,Rosén I,Lundgren J,Tideman E

更新日期：2013-12-01 00:00:00

abstract：:The present paper reports a family settled in the northern part of Norway, with a hereditary neurological disorder consisting clinically of spastic paraplegia associated with neurogenic bladder disturbances and syndactylia. Nine out of 22 members in three generations exhibit these clinical features. The bladder distur...

journal_title：Acta neurologica Scandinavica

authors： Opjordsmoen S,Nyberg-Hansen R

更新日期：1980-01-01 00:00:00