Long-term effect of intravenous immunoglobulin on anti-MuSK antibody-positive myasthenia gravis.

Abstract:

:Anti-muscle-specific receptor tyrosine kinase (MuSK) antibody-positive myasthenia gravis (MG) patients show various responses to conventional immunosuppressive treatment and some patients are resistant to these therapies. We report a 50-year-old Japanese man with anti-MuSK antibody-positive MG, who showed no or poor response to various therapies, including plasmapheresis, corticosteroid, and tacrolimus. The patient was then treated with intravenous immunoglobulin (IVIG), and showed a good response that persisted over 20 months. The outcome of this case suggests that IVIG treatment may be an effective therapeutic option for anti-MuSK antibody-positive MG, with a potentially long-term effect.

journal_name

Acta Neurol Scand

authors

Shibata-Hamaguchi A,Samuraki M,Furui E,Iwasa K,Yoshikawa H,Hayashi S,Yamada M

doi

10.1111/j.1600-0404.2007.00877.x

subject

Has Abstract

pub_date

2007-12-01 00:00:00

pages

406-8

issue

6

eissn

0001-6314

issn

1600-0404

pii

ANE877

journal_volume

116

pub_type

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