Vitamin D and multiple sclerosis—from epidemiology to prevention.

abstract：OBJECTIVES:To explore adherence, persistence, and treatment patterns in patients with multiple sclerosis (MS) in Finland treated with disease-modifying therapies (DMTs) for active MS in 2005-2018. MATERIALS AND METHODS:The study cohort was identified using the Drug Prescription Register of Social Insurance Institute, ...

journal_title：Acta neurologica Scandinavica

authors： Lahdenperä S,Soilu-Hänninen M,Kuusisto HM,Atula S,Junnila J,Berglund A

更新日期：2020-12-01 00:00:00

abstract：:Factors at presentation which influenced the course of the disease and response to treatment were assessed in 125 de novo patients with Parkinson's disease. Ninety-eight patients were available for re-assessment at 5 years. Older patients presented earlier after the onset of symptoms, deteriorated more rapidly, and we...

journal_title：Acta neurologica Scandinavica

authors： Hely MA,Morris JG,Reid WG,O'Sullivan DJ,Williamson PM,Broe GA,Adena MA

更新日期：1995-12-01 00:00:00

abstract：INTRODUCTION:Cerebrospinal fluid (CSF) may provide markers of severity and outcome of optic neuritis. MATERIAL AND METHODS:We examined the CSF from 29 patients with acute monosymptomatic optic neuritis (AMON) for content of myelin basic protein-like material (MBPLM) and correlated the levels with results of cranial ma...

journal_title：Acta neurologica Scandinavica

authors： Frederiksen JL,Whitaker JN

更新日期：1996-11-01 00:00:00

abstract：OBJECTIVES:Little is known about the frequency of abnormal visually evoked potentials (VEPs) in patients with respiratory chain disorders (RCDs). We thus wanted to investigate the frequency of abnormal VEPs in RCDs, how often VEPs are abnormal despite normal visual acuity, and which of the VEP variables are most often ...

journal_title：Acta neurologica Scandinavica

authors： Finsterer J

更新日期：2001-07-01 00:00:00

abstract：:Intractable seizure disorder is a clinical as well as a diagnostic problem. We evaluated the clinical role of extensive EEGs among patients (n = 64) considered to suffer from intractable paroxysmal neurologic symptoms. By reducing antiepileptic medication, ictal events were recorded in 89% of the cases. From the clini...

journal_title：Acta neurologica Scandinavica

authors： Nousiainen U,Suomalainen T,Mervaala E

更新日期：1992-03-01 00:00:00

abstract：OBJECTIVE:Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a severe autoimmune disorder with a mortality of 5%-7%, but few studies have focused on the predictors of death in this disease. In this study, we aim to investigate predictors and causes of death in patients with anti-NMDAR encephalitis. METHODS:In ...

journal_title：Acta neurologica Scandinavica

authors： Chi X,Wang W,Huang C,Wu M,Zhang L,Li J,Zhou D

更新日期：2017-10-01 00:00:00

abstract：:Prognosticating the outcome of an unconscious patient continues to pose a serious challenge to the clinicians. BAERs are the latest addition to neurological diagnostic aids for predicting the outcome of coma. The relative value of BAERs in predicting the outcome of 15 comatosed meningoencephalitis patients has been st...

journal_title：Acta neurologica Scandinavica

authors： Jain S,Maheshwari MC

更新日期：1984-03-01 00:00:00

abstract：:This report describes a multiple sclerosis (MS)-like disorder in a male patient with Leber's hereditary optic neuropathy (LHON) harbouring the mitochondrial DNA 11778 base pair mutation. Given the population frequencies of MS and LHON, coincidental occurrence is unlikely. Hypothetically the mitochondrial mutation unde...

journal_title：Acta neurologica Scandinavica

authors： Olsen NK,Hansen AW,Nørby S,Edal AL,Jørgensen JR,Rosenberg T

更新日期：1995-05-01 00:00:00

abstract：OBJECTIVE:To explore the long-term effectiveness of rufinamide in managing Lennox-Gastaut Syndrome (LGS), other epileptic encephalopathies, and intractable focal epilepsies in adults and children in routine clinical practice. METHODS:A multicentre, retrospective chart review of patients prescribed adjunctive rufinamid...

journal_title：Acta neurologica Scandinavica

authors： Jaraba S,Santamarina E,Miró J,Toledo M,Molins A,Burcet J,Becerra JL,Raspall M,Pico G,Miravet E,Cano A,Fossas P,Fernández S,Falip M

更新日期：2017-01-01 00:00:00

abstract：:The concentrations of sulfur-containing amino acids (taurine, methionine, cystine, cystathionine, homocystine) in lumbar CSF from patients with consciousness disturbances and controls were measured, and it was investigated whether there was any correlation between the sequential changes of these amino acid concentrati...

journal_title：Acta neurologica Scandinavica

authors： Yanai Y,Shibasaki T,Kohno N,Mitsui T,Nakajima H

更新日期：1983-12-01 00:00:00

abstract：:Psychometric tests, visual reaction time tests and electroencephalograms were performed in 26 cirrhotic patients without overt portal-systemic encephalopathy and in 26 healthy individuals. Cirrhotics performed poorly, compared with controls, on intelligence, learning and memory, perceptual motor and spatial tests. Non...

journal_title：Acta neurologica Scandinavica

authors： Puca FM,Antonaci F,Panella C,Guglielmi FW,Barone M,Francavilla A,Cerutti R

更新日期：1989-04-01 00:00:00

abstract：:Five patients with chronic progressive multiple sclerosis (MS) and three control patients with lumbar disc herniation were treated with dexamethazone during 14 days. The effect on peripheral blood T-cell subsets and on the proliferative response of peripheral blood mononuclear cells (PBMC) to pokeweed mitogen (PWM) an...

journal_title：Acta neurologica Scandinavica

authors： Salmaggi A,Baldetorp B,Milanese C,Nespolo A,Parma R,Sandberg-Wollheim M

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVE:We performed a systematic review and meta-analysis to evaluate the proposed association of restless legs syndrome (RLS) with cerebrovascular/cardiovascular outcomes. METHODS:We calculated the corresponding odds ratios on the prevalence of cerebrovascular/cardiovascular risk factors and standardized mean diff...

journal_title：Acta neurologica Scandinavica

authors： Katsanos AH,Kosmidou M,Konitsiotis S,Tsivgoulis G,Fiolaki A,Kyritsis AP,Giannopoulos S

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to re-evaluate the clinical features of stroke in children, their outcome and the place of the different mechanisms, in the light of CT-scan and magnetic resonance imaging. METHODS:A 10-year review of the Dijon Childhood Neurology Clinic experience (1985-1995) identified 54 patient...

journal_title：Acta neurologica Scandinavica

authors： Giroud M,Lemesle M,Madinier G,Manceau E,Osseby GV,Dumas R

更新日期：1997-12-01 00:00:00

abstract：INTRODUCTION:The objective of this study was to describe facial myokymia in experimental animals accompanying kainic acid affects on facial motor neurons. MATERIAL & METHODS:Anesthetized cats were injected with kainic acid into the pons adjacent to the facial nucleus. Facial movements appeared shortly after the inject...

journal_title：Acta neurologica Scandinavica

authors： Zaaroor M,Starr A

更新日期：1997-01-01 00:00:00

abstract：:Three Alzheimer's disease patients with Pisa syndrome were presented. These patients were treated with cholinesterase inhibitors within a post-marketing surveillance study. The clinical and pharmacological histories of these patients suggest a relation between cholinesterase inhibitors and the pleurothotonus. The diff...

journal_title：Acta neurologica Scandinavica

authors： Vanacore N,Suzzareddu G,Maggini M,Casula A,Capelli P,Raschetti R

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Persons with multiple sclerosis (MS) engage in substantially less overall physical activity than healthy controls, but there is little information on public health rates of physical activity necessary for health benefits. PURPOSE:This study examined the rates of insufficient, moderate, and sufficient physic...

journal_title：Acta neurologica Scandinavica

authors： Motl RW,McAuley E,Sandroff BM,Hubbard EA

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:To clarify how chronic solvent abuse affects cognitive function using magnetic resonance imaging as an index of brain damage. MATERIAL AND METHODS:A total of 25 chronic solvent abusers underwent magnetic resonance imaging with quantitative neurometry and Wechsler Adult Intelligence Scales revised. RESULTS:T...

journal_title：Acta neurologica Scandinavica

authors： Yamanouchi N,Okada S,Kodama K,Sakamoto T,Sekine H,Hirai S,Murakami A,Komatsu N,Sato T

更新日期：1997-07-01 00:00:00

abstract：:The pulsatility index (PI) registered by the transcranial doppler (TCD) was examined in relation to arterial pCO2 (paCO2) and epidural pressure (ICP). In 10 normal subjects PI was studied during variations in paCO2. In 10 neurosurgical patients with head injuries concomitant measurements of PI and ICP were obtained. T...

journal_title：Acta neurologica Scandinavica

authors： Homburg AM,Jakobsen M,Enevoldsen E

更新日期：1993-06-01 00:00:00

abstract：:Among industrial solvents in present use trichloroethylene belongs to those which have been the concern of most neurological and occupational investigations since the beginning of this century. Reports on a broad spectrum of neurotoxicity are however mostly based on case-studies and accidental circumstances. The objec...

journal_title：Acta neurologica Scandinavica

authors： Rasmussen K,Arlien-Søborg P,Sabroe S

更新日期：1993-03-01 00:00:00

abstract：OBJECTIVES:Interindividual variability in intestinal absorption and bioavailability might contribute to inadequate control of seizures under treatment with carbamazepine and phenytoin. We therefore correlated intestinal expression levels and genetics of CYP3A4, CYP2C9/19, MDR1 and MRP2 with dose requirement and plasma ...

journal_title：Acta neurologica Scandinavica

authors： Simon C,Stieger B,Kullak-Ublick GA,Fried M,Mueller S,Fritschy JM,Wieser HG,Pauli-Magnus C

更新日期：2007-04-01 00:00:00

abstract：:Three patients at Stage II of subacute sclerosing panencephalitis (SSPE) were treated with semipurified alpha-interferon (IFN) using different combinations of intrathecal and intravenous routes: 1 x 10(6) IU of alpha-IFN were given every other day up to a total of 15 x 10(6) IU. Transient improvement of neurological s...

journal_title：Acta neurologica Scandinavica

authors： Maimone D,Grimaldi LM,Incorpora G,Biondi R,Sofia V,Mancuso GR,Siciliano L,Ruscica M,Pavone L

更新日期：1988-09-01 00:00:00

abstract：OBJECTIVES:Myotonic dystrophy type 1 (DM1) is caused by large expansions of cytosine-thymine-guanine (CTG)-repeats in myotonic dystrophy protein kinase (DMPK)-gene. This gene is highly polymorphic in healthy individuals. It has been proposed that expanded alleles originated from the group of large sized normal alleles....

journal_title：Acta neurologica Scandinavica

authors： Culjković B,Stojković O,Vukosavić S,Savić D,Rakocevic V,Apostolski S,Romac S

更新日期：2002-01-01 00:00:00

abstract：:Two patients who developed rhabdomyolysis secondary to generalized seizures are presented. Minor traumas of skeletal muscles due to seizures may be associated with myoglobinuria and the development of acute renal failure. The diagnosis rhabdomyolysis may easily be confirmed by following serum creatine kinase. Myoglobi...

journal_title：Acta neurologica Scandinavica

authors： Os I,Lyngdal PT

更新日期：1989-03-01 00:00:00

abstract：:OBJECTIVES - Determine whether bilateral subthalamic nucleus stimulation (STN-DBS) in Parkinson's disease (PD) is associated with an increase in neuropeptide Y (NPY) and/or resistance to inhibition by leptin in relation to post-surgery weight gain. MATERIALS AND METHODS - This prospective study included 20 patients wh...

journal_title：Acta neurologica Scandinavica

authors： Escamilla-Sevilla F,Pérez-Navarro MJ,Muñoz-Pasadas M,Sáez-Zea C,Jouma-Katati M,Piédrola-Maroto G,Ramírez-Navarro A,Mínguez-Castellanos A

更新日期：2011-10-01 00:00:00

abstract：:Using the macrophage electrophoretic mobility (MEM) test, the in vitro effects of oleic, linoleic and arachidonic acid, as well as Naudicell oil and methyl gamma-linolenate, on lymphocyte response to various antigens (PPD, thyroid antigen and EF) were studied in patients with mutiple sclerosis, patients with other neu...

journal_title：Acta neurologica Scandinavica

authors： Field EJ,Shenton BK

更新日期：1975-08-01 00:00:00

abstract：:This study investigated whether there are predictors for initial severity of ideomotor apraxia (IMA) in focal left-hemisphere vascular patients. One hundred and twenty-nine subjects were examined between 15 and 30 days post-onset. Twenty-five patients with bilateral lesions were also studied in order to delineate the ...

journal_title：Acta neurologica Scandinavica

authors： Basso A,Capitani E,Della Sala S,Laiacona M,Spinnler H

更新日期：1987-08-01 00:00:00

abstract：OBJECTIVE:To study the relationship between cerebral hemodynamics and clinical performance in normal pressure hydrocephalus (NPH), before and after surgery. MATERIAL AND METHODS:Ten patients were studied prospectively before and 3 months after shunt surgery by means of transcranial Doppler (TCD). Clinical performance ...

journal_title：Acta neurologica Scandinavica

authors： Bakker SL,Boon AJ,Wijnhoud AD,Dippel DW,Delwel EJ,Koudstaal PJ

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVES:Spinocerebellar ataxia type 7 is a rare autosomal dominant neurodegenerative disorder characterized by progressive cerebellar and retinal degeneration, described in various population groups in the literature. This is the first description from South Africa. The objective was to document the clinical and gen...

journal_title：Acta neurologica Scandinavica

authors： Modi G,Modi M,Martinus I,Rodda J,Saffer D

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVE:Assessment of usefulness of magnetoencephalography (MEG) as a novel non-invasive technique in the diagnostic evaluation of patients with recurrent seizures after unsuccessful epilepsy surgery. MATERIAL AND METHODS:Seventeen patients in whom epilepsy surgery had failed underwent reevaluation by means of MEG i...

journal_title：Acta neurologica Scandinavica

authors： Kirchberger K,Hummel C,Stefan H

更新日期：1998-07-01 00:00:00