Risk factors for mortality in patients with anti-NMDA receptor encephalitis.

abstract：:In order to approach the mechanism of chronic or relapsing course in human chronic inflammatory demyelinating polyradiculoneuropathy, we established a chronic model of experimental allergic neuritis (EAN) in juvenile guinea pigs, and investigated the underlying cellular immune phenomenon in comparison with acute EAN i...

journal_title：Acta neurologica Scandinavica

authors： Suzumura A,Sobue G,Sugimura K,Matsuoka Y,Sobue I

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Delayed-release dimethyl fumarate (DMF) treatment can be associated with reduced lymphocyte and leucocyte counts, which might persist after DMF discontinuation. CASE PRESENTATION:We report the case of a patient with severe disease reactivation despite prolonged lymphopenia after DMF discontinuation. We desc...

journal_title：Acta neurologica Scandinavica

authors： Zecca C,Antozzi CG,Torri Clerici V,Ferrazzini M,Mantegazza RE,Rossi S,Gobbi C

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:Dopamine neurotransmission is a critical factor for executive function, which is controlled by the prefrontal cortex in humans. Although the contribution of genetic factors to the regulation of brain dopaminergic activity is widely acknowledged, identification of a genotype-phenotype association has not yet ...

journal_title：Acta neurologica Scandinavica

authors： Mitaki S,Isomura M,Maniwa K,Yamasaki M,Nagai A,Nabika T,Yamaguchi S

更新日期：2013-01-01 00:00:00

abstract：:Vigabatrin (VGB), an irreversible inhibitor of gamma-aminobutyric acid (GABA) transaminase, is approved as adjunct treatment of refractory partial seizures as well as infantile spasms. Although VGB has been proven to be effective, its use is limited by the risk of retinopathy and associated peripheral visual field def...

journal_title：Acta neurologica Scandinavica

authors： Heim MK,Gidal BE

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVES:Hospital admission in otherwise healthy patients following a first unprovoked seizure is controversial. We aimed to evaluate the influence of admission in a neurology department on the identification of risk factors for seizure recurrence in patients with a first unprovoked seizure. MATERIALS AND METHODS:We...

journal_title：Acta neurologica Scandinavica

authors： Goldberg I,Neufeld MY,Auriel E,Gandelman-Marton R

更新日期：2013-07-01 00:00:00

abstract：:This report describes a multiple sclerosis (MS)-like disorder in a male patient with Leber's hereditary optic neuropathy (LHON) harbouring the mitochondrial DNA 11778 base pair mutation. Given the population frequencies of MS and LHON, coincidental occurrence is unlikely. Hypothetically the mitochondrial mutation unde...

journal_title：Acta neurologica Scandinavica

authors： Olsen NK,Hansen AW,Nørby S,Edal AL,Jørgensen JR,Rosenberg T

更新日期：1995-05-01 00:00:00

abstract：OBJECTIVES:To estimate the prevalence of thyroid diseases and the cumulative risk of thyroid diseases during a follow-up period after myasthenia gravis (MG) diagnosis compared with non-MG controls. MATERIALS AND METHODS:We used the Taiwan National Health Insurance Database linked to Registry of Catastrophic Illness da...

journal_title：Acta neurologica Scandinavica

authors： Chou CC,Huang MH,Lan WC,Kong SS,Kuo CF,Chou IJ

更新日期：2020-09-01 00:00:00

abstract：:The phosphomannosyl receptor system is responsible for both the receptor-mediated endocytosis and the intracellular transport of lysosomal enzymes. In the present study this receptor system was examined in affected muscles of patients with various neuromuscular diseases. The total activity of beta-N-acetyl-glucosamini...

journal_title：Acta neurologica Scandinavica

authors： Salminen A,Marjomäki V,Tolonen U,Myllylä VV

更新日期：1988-06-01 00:00:00

abstract：:There is evidence from several laboratories of an increased prevalence of circulating immuno-complexes (CIC) in diabetic patients. It has also been suggested that CIC are pathogenetically related to chronic diabetic complications. The aim of this study was to assess peripheral nerve function in children with Type 1 di...

journal_title：Acta neurologica Scandinavica

authors： Fierro B,Modica A,Cardella F,Raimondo D,Triolo G,Meli F

更新日期：1991-03-01 00:00:00

abstract：:We describe eight patients from three families presenting with myoclonus, ataxia, infrequent seizures and minimal intellectual impairment. All were Arabs from different parts of the Arabian peninsula. The new consensus on terminology, genetic and clinical definition of Baltic myoclonus, Ramsay Hunt syndrome and Unverr...

journal_title：Acta neurologica Scandinavica

authors： Shakir RA,Khan RA,al-Zuhair AG

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Post-stroke cognitive impairment (PSCI) occurs commonly and is linked with development of dementia. We investigated the relationship between demographic, clinical and stroke symptoms at stroke onset and the presence of PSCI at 1 and 3 years after stroke. METHODS:We accessed anonymized data from the Virtual ...

journal_title：Acta neurologica Scandinavica

authors： Arba F,Quinn T,Hankey GJ,Inzitari D,Ali M,Lees KR,VISTA Collaboration.

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:As part of a door-to-door survey of neurologic diseases, we investigated the prevalence of lumbosacral radiculopathy (LR) in two Sicilian municipalities (N = 14,540, as of November 1, 1987). MATERIAL & METHODS:During phase 1, we administered a brief screening instrument to subjects in the study population. ...

journal_title：Acta neurologica Scandinavica

authors： Savettieri G,Salemi G,Rocca WA,Meneghini F,D'Arpa A,Morgante L,Coraci MA,Reggio A,Grigoletto F,Di Perri R

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVES:To evaluate the contribution of the demographical, clinical, analytical and genetic factors to brain signal intensity changes in T2-weighted MR images in amyotrophic lateral sclerosis (ALS) patients and controls. METHODS:Susceptibility-weighted and FLAIR sequences were obtained in a 3T MR scanner. Iron-rela...

journal_title：Acta neurologica Scandinavica

authors： Vázquez-Costa JF,Mazón M,Carreres-Polo J,Hervás D,Pérez-Tur J,Martí-Bonmatí L,Sevilla T

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:Botulinum neurotoxin (BoNT) injections in the salivary glands and radiotherapy (RT) on these glands are commonly used to alleviate severe drooling in patients with amyotrophic lateral sclerosis (ALS). This study compares BoNT type A with RT based on patient-rated evaluations. MATERIALS & METHODS:A prospecti...

journal_title：Acta neurologica Scandinavica

authors： Weikamp JG,Schinagl DA,Verstappen CC,Schelhaas HJ,de Swart BJ,Kalf JG

更新日期：2016-09-01 00:00:00

abstract：:Treatment with intraventricular pentosan polysulphate (PPS) might be beneficial in patients with Creutzfeldt-Jakob disease. We report a 68-year-old woman with sporadic Creutzfeldt-Jakob disease who received continuous intraventricular PPS infusion (1-120 microg/kg/day) for 17 months starting 10 months after the onset ...

journal_title：Acta neurologica Scandinavica

authors： Terada T,Tsuboi Y,Obi T,Doh-ura K,Murayama S,Kitamoto T,Yamada T,Mizoguchi K

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:Focal brain ischemia induced in rodents by occlusion of the middle cerebral artery (MCA) is a widely used paradigm of human brain infarct. The objective of this study is to compare the effectiveness and reproducibility of MCA filament occlusion model in rats and mice. MATERIALS AND METHODS:A total of 140 ro...

journal_title：Acta neurologica Scandinavica

authors： Ardehali MR,Rondouin G

更新日期：2003-04-01 00:00:00

abstract：:Symptoms of acute renal failure were observed in an anorexia patient who had a history of frequent vomiting. The acute renal failure might have resulted from rhabdomyolysis subsequent to a disturbance of electrolyte balance. This acute renal failure might have resulted in death if not treated. We postulate that even a...

journal_title：Acta neurologica Scandinavica

authors： Abe K,Mezaki T,Hirono N,Udaka F,Kameyama M

更新日期：1990-01-01 00:00:00

abstract：:This study investigated whether there are predictors for initial severity of ideomotor apraxia (IMA) in focal left-hemisphere vascular patients. One hundred and twenty-nine subjects were examined between 15 and 30 days post-onset. Twenty-five patients with bilateral lesions were also studied in order to delineate the ...

journal_title：Acta neurologica Scandinavica

authors： Basso A,Capitani E,Della Sala S,Laiacona M,Spinnler H

更新日期：1987-08-01 00:00:00

abstract：:The genetic mutation underlying Huntington's disease (HD) has been identified as an expansion and instability of a specific CAG repeat sequence in a gene on chromosome 4. A simple polymerase chain reaction assay has been used for the assessment of the (CAG)n expansion in a 72-year-old woman with typical HD symptoms, b...

journal_title：Acta neurologica Scandinavica

authors： Bozza A,Malagù S,Calzolari E,Novelletto A,Pavoni M,del Senno L

更新日期：1995-08-01 00:00:00

abstract：OBJECTIVES:Myotonic dystrophy type 1 (DM1) is the most common adult-onset muscular dystrophy. It is associated with motor symptoms but patients also display non-motor symptoms such as particular personality traits. Studies have reported mixed results about personality characteristics which may be attributable to small ...

journal_title：Acta neurologica Scandinavica

authors： Bertrand JA,Jean S,Laberge L,Gagnon C,Mathieu J,Gagnon JF,Richer L

更新日期：2015-07-01 00:00:00

abstract：:Twenty-four male patients, all homosexual except one, with asymptomatic HIV-infection were studied. The patients had no signs of opportunistic CNS-infections but 6 had been treated for syphilis. The patients were tested with auditory brainstem response (ABR) audiometry and with oculomotor tests (saccades and smooth pu...

journal_title：Acta neurologica Scandinavica

authors： Rosenhall U,Håkansson C,Löwhagen GB,Hanner P,Jonsson-Ehk B

更新日期：1989-02-01 00:00:00

abstract：OBJECTIVES:To assess the correlation of diffusion-weighted (DWI) and perfusion-weighted imaging (PWI) findings with the severity of acute neurologic deficit and their ability to predict short and long-term clinical outcomes of stroke. The ability of DWI and PWI to predict the outcome was compared with the ability of cl...

journal_title：Acta neurologica Scandinavica

authors： Nuutinen J,Liu Y,Laakso MP,Karonen JO,Roivainen R,Vanninen RL,Partanen K,Østergaard L,Sivenius J,Aronen HJ

更新日期：2006-02-01 00:00:00

abstract：:Three patients at Stage II of subacute sclerosing panencephalitis (SSPE) were treated with semipurified alpha-interferon (IFN) using different combinations of intrathecal and intravenous routes: 1 x 10(6) IU of alpha-IFN were given every other day up to a total of 15 x 10(6) IU. Transient improvement of neurological s...

journal_title：Acta neurologica Scandinavica

authors： Maimone D,Grimaldi LM,Incorpora G,Biondi R,Sofia V,Mancuso GR,Siciliano L,Ruscica M,Pavone L

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:Autoimmune encephalitis (AE) is a rare but debilitating neurological disease where the body develops antibodies against neuronal cell surface/synaptic proteins. Rituximab is an anti-CD20 chimeric monoclonal antibody which shows promise in AE treatment observational studies. To our knowledge, there has been n...

journal_title：Acta neurologica Scandinavica

authors： Nepal G,Shing YK,Yadav JK,Rehrig JH,Ojha R,Huang DY,Gajurel BP

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:In a previous study, we found that nine of the 47 siblings to multiple sclerosis (MS) patients with a normal neurologic examination carry an intrathecal oligoclonal immunopathy with limited specificity, a condition we termed MS immunopathic trait. Here we searched for neurological dysfunction with increased s...

journal_title：Acta neurologica Scandinavica

authors： Haghighi S,Frisén L,Odén A,Andersen O

更新日期：2003-11-01 00:00:00

abstract：:Once believed to be extremely uncommon, due to magnetic resonance imaging cavernous hemangiomas of the spinal cord are detected with increasing frequency. Management of both symptomatic and asymptomatic intramedullary cavernous hamangiomas is therefore of growing importance. However, experience with treatment and foll...

journal_title：Acta neurologica Scandinavica

authors： Kondziella D,Brodersen P,Laursen H,Hansen K

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVES:Parkinson's disease (PD) may be associated with increased energy metabolism in overactive regions of the basal ganglia. Therefore, we hypothesized that treatment with the N-methyl-d-aspartate receptor (NMDAR) antagonist memantine would decrease regional cerebral blood flow (rCBF) and oxygen metabolism in the...

journal_title：Acta neurologica Scandinavica

authors： Borghammer P,Vafaee M,Ostergaard K,Rodell A,Bailey C,Cumming P

更新日期：2008-05-01 00:00:00

abstract：:The pulsatility index (PI) registered by the transcranial doppler (TCD) was examined in relation to arterial pCO2 (paCO2) and epidural pressure (ICP). In 10 normal subjects PI was studied during variations in paCO2. In 10 neurosurgical patients with head injuries concomitant measurements of PI and ICP were obtained. T...

journal_title：Acta neurologica Scandinavica

authors： Homburg AM,Jakobsen M,Enevoldsen E

更新日期：1993-06-01 00:00:00

abstract：MATERIALS AND METHODS:In a prospective study we evaluated patients with first generalized tonic-clonic seizure (GTCS) (n = 16, age: 31 +/- 11 years, 8 women) and patients with vaso-vagal syncope (VVS) (n = 17, age: 32 +/- 13 years, 8 women), diagnosed on the basis of past history and clinical presentation who had serum...

journal_title：Acta neurologica Scandinavica

authors： Neufeld MY,Treves TA,Chistik V,Korczyn AD

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:To assess hemispheric differences in the duration of focal onset seizures and its association with clinical and demographic factors. METHODS:A retrospective analysis was performed on adult patients with drug-resistant unifocal epilepsy, who underwent intracranial EEG recording between 01/2006 and 06/2016. Se...

journal_title：Acta neurologica Scandinavica

authors： Seethaler M,Lauseker M,Ernst K,Rémi J,Vollmar C,Noachtar S,Kaufmann E

更新日期：2020-10-04 00:00:00