Leber's hereditary optic neuropathy associated with a disorder indistinguishable from multiple sclerosis in a male harbouring the mitochondrial DNA 11778 mutation.

abstract：OBJECTIVES:The well-being and physical function among patients with ALS and their next of kin was studied over time. MATERIALS AND METHODS:Thirty-five patients with ALS and their next of kin were studied with respect to physical, general and psychological well-being by the visual analogue scale (VAS) every 4-6 months....

journal_title：Acta neurologica Scandinavica

authors： Olsson AG,Markhede I,Strang S,Persson LI

更新日期：2010-04-01 00:00:00

abstract：:Transitional progressive multiple sclerosis (MS) is quite an unusual form of presentation and course of the disease. A case with this progressive form is presented and brain MRI and MTI findings are discussed in relation to the possible insight they may provide for understanding the mechanisms that determine progressi...

journal_title：Acta neurologica Scandinavica

authors： Filippi M,Campi A,Martinelli V,Pereira C,Scotti G,Comi G

更新日期：1995-08-01 00:00:00

abstract：OBJECTIVE:To determine characteristics, clinical significance, frequency, and mimics of restless legs syndrome (RLS) in a cohort of Wilson's disease (WD, n = 42/f = 18), compared to healthy, matched controls. MATERIALS AND METHODS:Structured clinical interviews (patients and caregiving family members), repeated neurol...

journal_title：Acta neurologica Scandinavica

authors： Trindade MC,Bittencourt T,Lorenzi-Filho G,Alves RC,de Andrade DC,Fonoff ET,Bor-Seng-Shu E,Machado AA,Teixeira MJ,Barbosa ER,Tribl GG

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:We aimed to study knee proprioception and somatosensory evoked potentials (SEPs) to stimulation of the common peroneal nerve (CPN) in 7 patients with lesion of the anterior cruciate ligament (ACL) before and after ACL reconstruction. MATERIALS AND METHODS:We recorded the spinal N14 and scalp P27 potentials ...

journal_title：Acta neurologica Scandinavica

authors： Valeriani M,Restuccia D,Di Lazzaro V,Franceschi F,Fabbriciani C,Tonali P

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVES:We evaluated the expression of chemokine-like factor (CKLF) in biopsied muscle fibers in inflammatory myopathies, non-inflammatory myopathies and neurologically diseased controls. MATERIALS AND METHODS:We studied the expression of CKLF in 15 polymyositis (PM), five dermatomyositis (DM), 15 non-inflammatory ...

journal_title：Acta neurologica Scandinavica

authors： Chowdhury MH,Nagai A,Terashima M,Sheikh A,Murakawa Y,Kobayashi S,Yamaguchi S

更新日期：2008-08-01 00:00:00

abstract：:It has been suggested that nitric oxide could be implicated in the neuronal degeneration of substantia nigra compacta in patients with Parkinson's disease. Recently, it has been reported decreased CSF nitrate levels (oxidation product that provides an indirect estimation of nitric oxide) in Parkinson's disease patient...

journal_title：Acta neurologica Scandinavica

authors： Molina JA,Jiménez-Jiménez FJ,Navarro JA,Vargas C,Gómez P,Benito-León J,Ortí-Pareja M,Cisneros E,Arenas J

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:White blood cells might have a pathogenetic role in ischemic vascular conditions. Several studies have suggested that increased adhesiveness of these cells could contribute to such a damage. The present study was undertaken in order to examine the adhesive properties of leukocytes in the peripheral blood of p...

journal_title：Acta neurologica Scandinavica

authors： Meiner Z,Arber N,Liberman E,Leibovitz E,Seltzer D,Berliner S

更新日期：1997-08-01 00:00:00

abstract：:We present 2 sibs with autosomal recessive spastic paraparesis and severe amyotrophy of the distal limb muscles. Elaborate neurophysiologic studies disclosed slight to moderate slowing of motor conduction, moderate to severe reduction of motor action potentials, denervation potentials, and increased distal motor laten...

journal_title：Acta neurologica Scandinavica

authors： Bruyn RP,Scheltens P,Lycklama à Nijeholt J,de Jong JM

更新日期：1993-06-01 00:00:00

abstract：:To clarify the central nervous and the cardiovascular mechanisms mediating the Cushing response (CR) during intracranial hypertension, the effects of continuous and prolonged expansion of an epidural supratentorial balloon was studied in six dogs. Regional cerebral blood flow, cardiac output, extracerebral tissue bloo...

journal_title：Acta neurologica Scandinavica

authors： Schrader H,Hall C,Zwetnow NN

更新日期：1985-09-01 00:00:00

abstract：:Twenty-four male patients, all homosexual except one, with asymptomatic HIV-infection were studied. The patients had no signs of opportunistic CNS-infections but 6 had been treated for syphilis. The patients were tested with auditory brainstem response (ABR) audiometry and with oculomotor tests (saccades and smooth pu...

journal_title：Acta neurologica Scandinavica

authors： Rosenhall U,Håkansson C,Löwhagen GB,Hanner P,Jonsson-Ehk B

更新日期：1989-02-01 00:00:00

abstract：:The F response can provide a measure of motoneurone excitability (MNE) and so it may be used to investigate upper motoneurone disorders. This report studies the F-wave configuration in patients with stroke to evaluate the changes of the central excitability of the motoneurones at different times after an acute cerebra...

journal_title：Acta neurologica Scandinavica

authors： Fierro B,Raimondo D,Modica A

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVES:To investigate efficacy and safety of entacapone across phase III studies in Parkinson's disease (PD) with wearing-off symptoms. METHODS:Retrospective, pooled analysis of four phase 3 randomized, double-blind, placebo-controlled studies with entacapone. RESULTS:475 of 808 patients with PD received entacapo...

journal_title：Acta neurologica Scandinavica

authors： Kuoppamäki M,Vahteristo M,Ellmén J,Kieburtz K

更新日期：2014-10-01 00:00:00

abstract：:The concentrations of sulfur-containing amino acids (taurine, methionine, cystine, cystathionine, homocystine) in lumbar CSF from patients with consciousness disturbances and controls were measured, and it was investigated whether there was any correlation between the sequential changes of these amino acid concentrati...

journal_title：Acta neurologica Scandinavica

authors： Yanai Y,Shibasaki T,Kohno N,Mitsui T,Nakajima H

更新日期：1983-12-01 00:00:00

abstract：OBJECTIVE:To investigate dopamine reuptake sites (dopamine transporter) in the caudate nucleus and putamen in narcolepsy. PATIENTS AND METHODS:Ten patients with narcolepsy and 15 controls were studied with positron emission tomography. A cocaine analogue [11C]-CFT was used as a radioligand. RESULTS:The uptake of[11C]...

journal_title：Acta neurologica Scandinavica

authors： Rinne JO,Hublin C,Någren K,Helenius H,Partinen M

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVES:Fatigue and apathy are two of the most common and most disabling non-motor symptoms of Parkinson's disease (PD). They have a high coincidence and can often be confused; moreover, their relationship is not fully understood. The aim of our study was to describe the coincidence of apathy with different fatigue ...

journal_title：Acta neurologica Scandinavica

authors： Skorvanek M,Gdovinova Z,Rosenberger J,Saeedian RG,Nagyova I,Groothoff JW,van Dijk JP

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:LMNB1-related autosomal dominant leukodystrophy is caused by an overexpression of the protein lamin B1, usually due to a duplication of the LMNB1 gene. Symptoms start in 5th to 6th decade. This slowly progressive disease terminates with death. We studied brain glucose metabolism in this disease using 18 F-flu...

journal_title：Acta neurologica Scandinavica

authors： Finnsson J,Lubberink M,Savitcheva I,Fällmar D,Melberg A,Kumlien E,Raininko R

更新日期：2019-02-01 00:00:00

abstract：:Febrile seizures occurred in 14 of 155 (9%) out-patients with complex partial seizures. Twelve patients had prolonged or recurrent febrile seizures, convulsive status epilepticus or a transient postictal neurological deficit. Febrile seizures were associated with perinatal abnormalities, an earlier onset of epilepsy a...

journal_title：Acta neurologica Scandinavica

authors： Schmidt D,Tsai JJ,Janz D

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVES:To investigate the frequency of ECG abnormalities suggestive of myocardial ischaemia in patients with severe drug resistant epilepsy and without any indication of previous cardiac disease, assuming that these changes may be of significance for the group of epileptic patients with sudden unexpected death. MA...

journal_title：Acta neurologica Scandinavica

authors： Tigaran S,Rasmussen V,Dam M,Pedersen S,Høgenhaven H,Friberg B

更新日期：1997-08-01 00:00:00

abstract：INTRODUCTION:Charcot-Marie-Tooth disease (CMT) is a heterogeneous inherited neuropathy. The number of known CMT genes is rapidly increasing mainly due to next-generation sequencing technology, at present more than 70 CMT-associated genes are known. We investigated whether variants in the DCTN2 could cause CMT. MATERIA...

journal_title：Acta neurologica Scandinavica

authors： Braathen GJ,Høyer H,Busk ØL,Tveten K,Skjelbred CF,Russell MB

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:To determine whether Parkinson's disease (PD) can be distinguished from multiple system atrophy (MSA) on the basis of the assessment of iodine-123 meta-iodobenzylguanidine (123I-MIBG) radioactivity in heart and cardiovascular autonomic function. PATIENTS AND METHODS:Seventeen patients with MSA, 39 with PD, ...

journal_title：Acta neurologica Scandinavica

authors： Oka H,Mochio S,Yoshioka M,Morita M,Onouchi K,Inoue K

更新日期：2006-04-01 00:00:00

abstract：:Adenylate kinase (AK) was determined in a lumbo-cisternal cerebrospinal fluid (CSF) gradient and in CSF from patients with mental deterioration. AK activity was unchanged in the gradient and different from albumin and albumin ratio (alb CSF/albumin serum), a blood-brain barrier marker in the same gradient. No differen...

journal_title：Acta neurologica Scandinavica

authors： Ahlberg J,Blomstrand C,Ronquist G,Wikkelsö C

更新日期：1985-11-01 00:00:00

abstract：:In a double-blind cross-over trial with placebo, FPL 57787, a chromone derivate, was tested on 15 patients as a prophylactic against migraine. There was found to be no effect. ...

journal_title：Acta neurologica Scandinavica

authors： Koch-Henriksen N,Sehested P

更新日期：1979-03-01 00:00:00

abstract：OBJECTIVES:The cost-effectiveness of available pharmacological treatments for narcolepsy is largely unknown. Available pharmacological treatments are associated with tolerability, abuse, and adherence issues. Pitolisant is the first inverse agonist of the histamine H3 receptor to be prescribed for the treatment of narc...

journal_title：Acta neurologica Scandinavica

authors： Bolin K,Niska PÅ,Pirhonen L,Wasling P,Landtblom AM

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Some previous studies reported an independent association between uric acid and coronary artery disease, while little is known on the association among uric acid and carotid artery disease (CAD). To address this issue, we investigated the association between CAD and higher uric acid level because...

journal_title：Acta neurologica Scandinavica

authors： Kumral E,Karaman B,Orman M,Kabaroglu C

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVES:Until now, the significance of plasma exchange (PE) as a treatment for steroid-unresponsive optic neuritis (ON) is still unclear because placebo-controlled and larger studies are missing. We report our experience with 23 patients treated by PE due to steroid-unresponsive ON. MATERIALS AND METHODS:Patients w...

journal_title：Acta neurologica Scandinavica

authors： Roesner S,Appel R,Gbadamosi J,Martin R,Heesen C

更新日期：2012-08-01 00:00:00

abstract：:We carried out a prospective study to determine the frequency and evolution of carpal tunnel syndrome (CTS) in patients with hyperthyroidism. An initial survey revealed CTS in 5% of these patients when hyperthyroidism was diagnosed. During the clinical and neurophysiologic follow-up for a two-year period, four more pa...

journal_title：Acta neurologica Scandinavica

authors： Roquer J,Cano JF

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVES:Oxidative stress and glutamate-mediated excitotoxicity may play an important role in the etiopathogenesis of amyotrophic lateral sclerosis (ALS). Prostaglandin E2 (PGE2) activity can be associated with motor neuron death by inducing free radical formation and glutamate release from astrocytes. The aim of thi...

journal_title：Acta neurologica Scandinavica

authors： Iłzecka J

更新日期：2003-08-01 00:00:00

abstract：INTRODUCTION:Cognitive impairment is a common and disabling consequence of stroke. Its prevalence, the best way to screen for it in the acute setting, and its relation with premorbid status have not been thoroughly clarified. MATERIALS AND METHODS:Ischemic and hemorrhagic stroke patients admitted to our stroke unit un...

journal_title：Acta neurologica Scandinavica

authors： Cova I,Mele F,Zerini F,Maggiore L,Cucumo V,Brambilla M,Rosa S,Bertora P,Salvadori E,Pomati S,Pantoni L

更新日期：2020-10-01 00:00:00

abstract：:Examinations with directional Doppler (DD) with 10 MHz transducer, and pulsed Doppler in combination with two-dimensional sector scanner with 3 MHz transducer (Duplex) were carried out on 100 vessels in 51 patients with transitory ischemic attacks (TIA) and minor stroke within the territory of the internal carotid art...

journal_title：Acta neurologica Scandinavica

authors： Zbornikova V,Akesson JA,Lassvik C

更新日期：1982-04-01 00:00:00

abstract：:Decompressive craniectomy is a neurosurgical technique in which a portion of the skull is removed to reduce intracranial pressure. The rationale for this procedure is based on the Monro-Kellie Doctrine; expanding the physical space confining edematous brain tissue after traumatic brain injury will reduce intracranial ...

journal_title：Acta neurologica Scandinavica

authors： Quinn TM,Taylor JJ,Magarik JA,Vought E,Kindy MS,Ellegala DB

更新日期：2011-04-01 00:00:00