Pooled analysis of phase III with entacapone in Parkinson's disease.

abstract：INTRODUCTION:We describe bilateral optic neuropathy in a patient affected by ovarian carcinoma treated with cis-platin 160 mg/m2 and carboplatin, 640 mg/m2. The patient was followed for 1 year, when recovery appeared. The few previous descriptions of CDDP optic nerve toxicity did not report recovery. METHODS:Computeri...

journal_title：Acta neurologica Scandinavica

authors： Caraceni A,Martini C,Spatti G,Thomas A,Onofrj M

更新日期：1997-10-01 00:00:00

abstract：:We describe the incidence and explore the quality of registered diagnosis for Guillain-Barré syndrome (GBS) in a population-based retrospective study in South-West Stockholm (SWS), Sweden, during the period 1973-1991. We used data on registered hospital discharges and open-care visits, and from medical records. Medica...

journal_title：Acta neurologica Scandinavica

authors： Jiang GX,de Pedro-Cuesta J,Fredrikson S

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the epidemiological and clinical features of motor neuron disease (MND) in a region (835,000 inhabitants) of south-western Greece. PATIENTS AND METHODS:The medical records of all patients diagnosed with adult-onset MND at the Department of Neurology of the University Hospital of Patras from 1990 ...

journal_title：Acta neurologica Scandinavica

authors： Argyriou AA,Polychronopoulos P,Papapetropoulos S,Ellul J,Andriopoulos I,Katsoulas G,Salakou S,Chroni E

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:The common prion protein gene (PRNP) codon 129 polymorphism modifies the susceptibility to and the phenotype of prion diseases. However, no truly representative normal population-based data, or data stratified according to age or gender are available on the distribution of this polymorphism. MATERIAL AND ME...

journal_title：Acta neurologica Scandinavica

authors： Nurmi MH,Bishop M,Strain L,Brett F,McGuigan C,Hutchison M,Farrell M,Tilvis R,Erkkilä S,Simell O,Knight R,Haltia M

更新日期：2003-11-01 00:00:00

abstract：:The clinical features in 268 patients with diffuse cerebral atrophy of initially unknown origin have been analysed. Pneumoencephalography showed supratentorial ventricular atrophy in 87 per cent (cortical in 71 per cent), and brain stem and/or cerebellar atrophy in 17 per cent of the patients. Epileptic seizures, dizz...

journal_title：Acta neurologica Scandinavica

authors： Iivanainen M

更新日期：1975-04-01 00:00:00

abstract：:Two cases of increased intracranial pressure associated with lumbar intraspinal tumours are reported. On the basis of protein investigations and constant flow infusion manometric tests, the pathophysiology of the increased intracranial pressure is discussed. It is demonstrated that protein macromolecules leak from the...

journal_title：Acta neurologica Scandinavica

authors： Borgesen SE,Sorensen SC,Olesen J,Gjerris F

更新日期：1977-09-01 00:00:00

abstract：:Debate about the lesion site in the Miller Fisher syndrome is still going on. We studied a patient with features of the Miller Fisher syndrome in whom arguments for both central and peripheral nervous system dysfunction were found. ...

journal_title：Acta neurologica Scandinavica

authors： Taphoorn MJ,Lanting P,Hazenberg GJ,Uitdehaag BJ,Kaiser MC

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVES:Interindividual variability in intestinal absorption and bioavailability might contribute to inadequate control of seizures under treatment with carbamazepine and phenytoin. We therefore correlated intestinal expression levels and genetics of CYP3A4, CYP2C9/19, MDR1 and MRP2 with dose requirement and plasma ...

journal_title：Acta neurologica Scandinavica

authors： Simon C,Stieger B,Kullak-Ublick GA,Fried M,Mueller S,Fritschy JM,Wieser HG,Pauli-Magnus C

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Autoimmune encephalitis (AE) is a rare but debilitating neurological disease where the body develops antibodies against neuronal cell surface/synaptic proteins. Rituximab is an anti-CD20 chimeric monoclonal antibody which shows promise in AE treatment observational studies. To our knowledge, there has been n...

journal_title：Acta neurologica Scandinavica

authors： Nepal G,Shing YK,Yadav JK,Rehrig JH,Ojha R,Huang DY,Gajurel BP

更新日期：2020-11-01 00:00:00

abstract：:A 54 year-old woman showed the unusual association of a Guillain-Barré syndrome and opsoclonus, a rare eye movement characterized by involuntary bursts of jerking, ataxic and multidirectional saccades, without an intersaccadic interval. Since opsoclonus is a phenomenon described exclusively in CNS diseases, the case r...

journal_title：Acta neurologica Scandinavica

authors： Nicolai A,Lazzarino LG

更新日期：1992-05-01 00:00:00

abstract：:Several forms of treatment of lower urinary tract functional disorders have been attempted in children with myelomeningocele (MMC). Intravesical electrical stimulation was attempted in 10 patients. Urinary control was achieved in one and in the remaining 9 either the bladder was resistant to stimulation or the childre...

journal_title：Acta neurologica Scandinavica

authors： Petersen T

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Variants in genes encoding enzymes involved in production, aggregation or degradation of beta-amyloid are potential risk factors for sporadic Alzheimer's disease (AD). METHODS:Meta-analyses on AD association with BACE1 exon 5, BACE1 intron 5, FE65 intron 13, CYP46 intron 2, alpha(1)-antichymotrypsine Ala17T...

journal_title：Acta neurologica Scandinavica

authors： Llorca J,Rodríguez-Rodríguez E,Dierssen-Sotos T,Delgado-Rodríguez M,Berciano J,Combarros O

更新日期：2008-01-01 00:00:00

abstract：:This study concerns the distribution of T-cell subsets as determined by specific monoclonal antibodies in 50 individuals with complex partial seizures (31) and primary generalized tonic-clonic seizures (19), and in 30 healthy controls. The epileptic group had significantly fewer circulating T4 "helper" lymphocytes and...

journal_title：Acta neurologica Scandinavica

authors： Eeg-Olofsson O,Prchal JF,Andermann F

更新日期：1985-08-01 00:00:00

abstract：:Eleven patients with presenile Alzheimer type dementia (ATD) were treated with N-terminal ACTH fragments for 14 days. No change in cognitive functions was observed during the treatment. A significant increase in CSF beta-endorphin (beta-EP) levels was found, while ACTH and beta-lipoprotein remain unaffected. The possi...

journal_title：Acta neurologica Scandinavica

authors： Nappi G,Facchinetti F,Martignoni E,Petraglia F,Sinforiani E,Bono G,Genazzani AR

更新日期：1988-08-01 00:00:00

abstract：:We report 20 cases of right unilateral spatial neglect caused by lesions in the left cerebral hemisphere. Differences in neuropsychological symptoms and lesions sites are discussed in connection with handedness. Of the right-handed patients, 6 had severe aphasia, 4 had Gerstmann's syndrome, and 1 had pure agraphia, bu...

journal_title：Acta neurologica Scandinavica

authors： Maeshima S,Shigeno K,Dohi N,Kajiwara T,Komai N

更新日期：1992-06-01 00:00:00

abstract：:A two-phase epidemiological study of essential tremor was carried out by investigating a rural population aged over 40 years in 2 municipalities in southwestern Finland. In the first phase, the subjects answered a questionnaire as to whether they had experienced tremor during the month preceding the inquiry. In the se...

journal_title：Acta neurologica Scandinavica

authors： Rautakorpi I,Takala J,Marttila RJ,Sievers K,Rinne UK

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral infarcts occur more frequently along the middle (MCA) than the anterior cerebral artery (ACA) territory. The reason(s) for this difference remains speculative. The objective of this study was to investigate the distribution of cerebral microemboli as detected by transcranial Doppler ultr...

journal_title：Acta neurologica Scandinavica

authors： Wijman CA,Babikian VL,Winter MR,Pochay VE

更新日期：2000-02-01 00:00:00

abstract：:Cognitive deficits have been reported in 45%-70% of patients with multiple sclerosis (MS). Like other symptoms of MS, cognitive deficits are highly variable. Slowed information processing and memory and learning dysfunction are regarded as the most frequent cognitive deficits in MS. Both white and gray matter damages ...

journal_title：Acta neurologica Scandinavica

authors： Hämäläinen P,Rosti-Otajärvi E

更新日期：2016-09-01 00:00:00

abstract：:Multiple system atrophy (MSA) is a heterogeneous group of central neurological degenerations often associated with diffuse deterioration of the hypothalamic cholinergic neurons. In the hypothesis of an altered cholinergic regulation of vasopressin release, we evaluated vasopressin response to metoclopramide (20 mg i.v...

journal_title：Acta neurologica Scandinavica

authors： Norbiato G,Bevilacqua M,Righini V,Chebat E,Vago T,Bertora P,Castelli L,Mangoni A

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:Bilateral hippocampal abnormality is frequent in mesial temporal lobe sclerosis and might affect outcome in epilepsy surgery. The objective of this study was to compare the lateralization of interictal and ictal scalp EEG with MRI T2 relaxometry. MATERIAL AND METHODS:Forty-nine consecutive patients with intr...

journal_title：Acta neurologica Scandinavica

authors： Okujava M,Schulz R,Hoppe M,Ebner A,Jokeit H,Woermann FG

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:The quality-of-life (QoL) perception by Parkinson's disease (PD) patients and their caregivers (CG) has not been studied in depth. OBJECTIVE:To examine patient/proxy agreements on the PD QoL Questionnaire (PDQ-39), the Scale of Quality of Life of Care-Givers (SQLC) and the Multidimensional Caregiver Strain ...

journal_title：Acta neurologica Scandinavica

authors： Balash Y,Korczyn AD,Knaani J,Migirov AA,Gurevich T

更新日期：2017-08-01 00:00:00

abstract：:EEG data obtained from 27 patients with presenile Alzheimer's disease (AD) and 28 patients with senile dementia of the Alzheimer type (SDAT) were compared with data from 30 age- and sex-matched controls. Both patient groups exhibited more pronounced delta and theta activity and less prominent alpha and beta activity t...

journal_title：Acta neurologica Scandinavica

authors： Miyauchi T,Hagimoto H,Ishii M,Endo S,Tanaka K,Kajiwara S,Endo K,Kajiwara A,Kosaka K

更新日期：1994-01-01 00:00:00

abstract：:A purified citric acid soluble extract from human skeletal muscle (AEMA) and a phosphate-buffered saline extract from rabbit muscle acetone powder (EMA) were used to coat polystyrene beads in an enzyme-linked immunosorbent assay (ELISA). From 54 patients with myasthenia gravis, positive results were observed in 14. Fi...

journal_title：Acta neurologica Scandinavica

authors： Viana VS,Bueno C,Marchiori PE,Oliveira RM,Assis JL,Scaff M,Cossermelli W

更新日期：1986-06-01 00:00:00

abstract：:Serum lipids and the cholesterol concentration in the high density lipoprotein (HDL) fraction were measured in epileptic patients taking either carbamazepine or phenytoin as single drug treatment. There was a significant increase in HDL-cholesterol levels in patients taking both phenytoin and carbamazepine. Serum tota...

journal_title：Acta neurologica Scandinavica

authors： O'Neill B,Callaghan N,Stapleton M,Molloy W

更新日期：1982-02-01 00:00:00

abstract：:Twenty patients with paralysis agitans took part in a double-blind, cross-over investigation of CB 154 (2-bromo-alpha-ergocryptine) and Madopar (L-Dopa + benserazid (a peripheral decarboxylase inhibitor), dose ratio 4:1). Each treatment phase lasted for 8 weeks. Modapar was found to be significantly superior to CB 154...

journal_title：Acta neurologica Scandinavica

authors： Gerlach J

更新日期：1976-03-01 00:00:00

abstract：OBJECTIVES:The epidemiology, manifestations, and course of Parkinson's disease (PD) may differ in men and women. Assessments of severity of the illness and quality of life (QoL), and the burden on their caregivers (CG) may change as the disease advances. We determined gender differences in assessment by patients with P...

journal_title：Acta neurologica Scandinavica

authors： Balash Y,Korczyn AD,Migirov AA,Gurevich T

更新日期：2019-07-01 00:00:00

abstract：:Patients with aseptic meningitis (AM) were examined with the active T cell rosette test, which has been claimed to reflect cell-mediated immunocompetence more accurately than determination of total T cells. Higher percentages of active T cells were demonstrated in CSF compared to blood regardless if specimens were obt...

journal_title：Acta neurologica Scandinavica

authors： Frydén A,Kam-Hansen S,Maller R,Link H

更新日期：1980-05-01 00:00:00

abstract：:The present communication is devoted to investigating the possibility that in myotonic dystrophy (MyD) a decreased ATP utilization by the membrane may produce modifications in glycoprotein structure and/or in the supramolecular arrangement of some membrane proteins. The study was carried out a) by determining the memb...

journal_title：Acta neurologica Scandinavica

authors： Sandrini G,Bottiroli G,Nappi G,Balduini C,Brovelli A

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Elevated levels of the cerebrospinal fluid (CSF) neuronal injury markers (neurofilament light chain [NF-L] and total tau protein [t-tau]) and of the astroglial marker glial fibrillary acidic protein (GFAP) are found in etiologically different neurological disorders affecting the peripheral and the central ne...

journal_title：Acta neurologica Scandinavica

authors： Constantinescu R,Mahamud U,Constantinescu C,Eriksson B,Novakova L,Olsson B,Rosengren L,Blennow K,Axelsson M

更新日期：2019-09-01 00:00:00

abstract：:A representative sample of 117 patients with definite multiple sclerosis (MS) was interviewed on pain syndromes. Chronic syndromes lasting more than one month included dysaestesthesia, low back pain, spasms, tonic seizures, tightening and painful sensations in the extremities. Acute syndromes included neuralgia, L'Her...

journal_title：Acta neurologica Scandinavica

authors： Stenager E,Knudsen L,Jensen K

更新日期：1991-09-01 00:00:00