Serum elevation of high density lipoprotein (HDL) cholesterol in epileptic patients taking carbamazepine or phenytoin.

Abstract:

:Serum lipids and the cholesterol concentration in the high density lipoprotein (HDL) fraction were measured in epileptic patients taking either carbamazepine or phenytoin as single drug treatment. There was a significant increase in HDL-cholesterol levels in patients taking both phenytoin and carbamazepine. Serum total-cholesterol concentrations in patients taking both drugs did not differ significantly from those of controls. The ratio of HDL-cholesterol/total cholesterol was increased in both drugs and the increase reached significance in patients taking phenytoin. There was a significant increase in serum triglycerides in females taking carbamazepine.

journal_name

Acta Neurol Scand

authors

O'Neill B,Callaghan N,Stapleton M,Molloy W

doi

10.1111/j.1600-0404.1982.tb03067.x

subject

Has Abstract

pub_date

1982-02-01 00:00:00

pages

104-9

issue

2

eissn

0001-6314

issn

1600-0404

journal_volume

65

pub_type

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