Cognitive impairment in MS: rehabilitation approaches.

Abstract:

:Cognitive deficits have been reported in 45%-70% of patients with multiple sclerosis (MS). Like other symptoms of MS, cognitive deficits are highly variable. Slowed information processing and memory and learning dysfunction are regarded as the most frequent cognitive deficits in MS. Both white and gray matter damages have been suggested to contribute to cognitive impairments in MS. There is no direct relationship between cognitive deficits and physical disability, disease duration or course of the disease. In addition to cognitive impairments, neuropsychiatric symptoms are observed in MS, the most common being alterations in mood state. Neurobehavioral deficits have multidimensional effects on the activities of daily living and quality of life. Consequently, attention should be paid to early diagnosis and treatment. Based on studies on cognitive retraining and more multimodal neuropsychological rehabilitation, both approaches show promise in the treatment of cognitive impairments and their harmful effects. This review introduces the frequency and characteristics of cognitive impairments, as well as main findings on the effects of neuropsychological rehabilitation in MS.

journal_name

Acta Neurol Scand

authors

Hämäläinen P,Rosti-Otajärvi E

doi

10.1111/ane.12650

subject

Has Abstract

pub_date

2016-09-01 00:00:00

pages

8-13

eissn

0001-6314

issn

1600-0404

journal_volume

134 Suppl 200

pub_type

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