The cost utility of pitolisant as narcolepsy treatment.

abstract：:Electromyograms (EMGs) are usually considered artifacts during electroencephalographic (EEG) recording for determination of electrocerebral silence (ECS). Appearance of scalp motor unit activity, however, may reflect residual brainstem function and can introduce difficulty in establishing a secure diagnosis of brain d...

journal_title：Acta neurologica Scandinavica

authors： Wee AS

更新日期：1986-08-01 00:00:00

abstract：:Alterations in nervous system functioning following acute and chronic ethanol exposure have been studied in a great number of experimental investigations. Results from many of these investigations can be difficult to interpret, particularly since a variety of techniques and exposure models are employed. This review em...

journal_title：Acta neurologica Scandinavica

authors： Melgaard B

更新日期：1983-03-01 00:00:00

abstract：OBJECTIVES:To study the effects of different colour imaging modes on the contrast-medium-enhanced image of the intracranial cerebral arteries. METHODS:Twelve healthy volunteers were studied transcranially after administration of 10 ml BY963 successively with Power Doppler (p-TCCS) and with colour Doppler frequency ima...

journal_title：Acta neurologica Scandinavica

authors： Kaps M,Schaffer P,Beller KD,Seidel G,Wurst W

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVE:LMNB1-related autosomal dominant leukodystrophy is caused by an overexpression of the protein lamin B1, usually due to a duplication of the LMNB1 gene. Symptoms start in 5th to 6th decade. This slowly progressive disease terminates with death. We studied brain glucose metabolism in this disease using 18 F-flu...

journal_title：Acta neurologica Scandinavica

authors： Finnsson J,Lubberink M,Savitcheva I,Fällmar D,Melberg A,Kumlien E,Raininko R

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the existence of polyautoimmunity in a Greek cohort of multiple sclerosis (MS), particularly multiple autoimmune syndrome (MAS), i.e., the presence of three or more distinct autoimmune disorders (ADs) in the same individual. METHODS:Cross-sectional control study. RESULTS...

journal_title：Acta neurologica Scandinavica

authors： Deretzi G,Kountouras J,Polyzos SA,Koutlas E,Pelidou SH,Xeromerisiou G,Zavos C,Tsiptsios I

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVES:A previous epidemiological study of Parkinson's disease (PD) in the county of Tartu, Estonia, found an adjusted prevalence rate of 152/100 000 persons. We aimed to determine PD prevalence almost 20 years later, as well as evaluate any dynamic changes in disease frequency compared to the first study. METHODS...

journal_title：Acta neurologica Scandinavica

authors： Kadastik-Eerme L,Taba N,Asser T,Taba P

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:To describe spinal epidural abscess after treatment with rituximab. METHODS:Report of a new case of cervical epidural spinal abscess after treatment with rituximab and review of the literature. RESULTS:Biologic agents are associated with an increased risk of serious infections, there are only few reports of...

journal_title：Acta neurologica Scandinavica

authors： Avila JD,Živković S

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:Blepharoclonus (BLC) denotes a large amplitude, involuntary tremors of the orbicularis oculi muscles, observed during gentle closure of the eyelids. BLC may follow major head trauma. Four patients with Arnold-Chiari malformation (ACM) and BLC are described. MATERIALS AND METHODS:The first patient had facial ...

journal_title：Acta neurologica Scandinavica

authors： Jacome DE

更新日期：2001-08-01 00:00:00

abstract：:Two patients who developed rhabdomyolysis secondary to generalized seizures are presented. Minor traumas of skeletal muscles due to seizures may be associated with myoglobinuria and the development of acute renal failure. The diagnosis rhabdomyolysis may easily be confirmed by following serum creatine kinase. Myoglobi...

journal_title：Acta neurologica Scandinavica

authors： Os I,Lyngdal PT

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to re-evaluate the clinical features of stroke in children, their outcome and the place of the different mechanisms, in the light of CT-scan and magnetic resonance imaging. METHODS:A 10-year review of the Dijon Childhood Neurology Clinic experience (1985-1995) identified 54 patient...

journal_title：Acta neurologica Scandinavica

authors： Giroud M,Lemesle M,Madinier G,Manceau E,Osseby GV,Dumas R

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of Rhesus anti-D immunoglobulin (anti-D) in patients with an autoimmune demyelinating neuropathy. MATERIAL AND METHODS:Three patients with an autoimmune mediated neuropathy received 1000 IU anti-D weekly for 2 months. RESULTS:Two patients worsened gradually during the treatment and...

journal_title：Acta neurologica Scandinavica

authors： de Jager AE,Hazenberg CA,van der Hoeven JH

更新日期：1998-07-01 00:00:00

abstract：:We studied a Becker muscular dystrophy (BMD) family with a manifesting carrier. Proximal muscle weakness, pseudohypertrophy of the calves, significantly elevated serum creatine kinase and dystrophic alterations in the muscle biopsy were the characteristic phenotypical features of this manifesting carrier. The recombin...

journal_title：Acta neurologica Scandinavica

authors： Ionasescu VV,Searby CC,Ionasescu R

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVES:Vascular endothelial growth factor (VEGF) acts in angiogenesis and neuroprotection, although the beneficial effects on experimental ischemic stroke (IS) have not been replicated in clinical studies. We investigated serum VEGF (s-VEGF) in the acute stage (baseline) and 3 months post-stroke in relation to stro...

journal_title：Acta neurologica Scandinavica

authors： Åberg ND,Wall A,Anger O,Jood K,Andreasson U,Blennow K,Zetterberg H,Isgaard J,Jern C,Svensson J

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to examine the effects of D-amphetamine (D-amph) and physical therapy separately or combined on fine motor performance, gross motor performance and cognition after middle cerebral artery thromboembolization in rats. METHODS:Seventy-four rats were trained in appropri...

journal_title：Acta neurologica Scandinavica

authors： Rasmussen RS,Overgaard K,Hildebrandt-Eriksen ES,Boysen G

更新日期：2006-03-01 00:00:00

abstract：:Amino acid concentrations in plasma of patients with Huntington's disease (HD) were determined in 16 patients and 21 age- and sex-matched healthy controls. Alanine and isoleucine were significantly decreased in HD plasma whereas arginine, histidine, leucine, lysine, ornithine, proline, serine, threonine, tyrosine, and...

journal_title：Acta neurologica Scandinavica

authors： Reilmann R,Rolf LH,Lange HW

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVE:White matter (WM) integrity of Spinocerebellar ataxia 2 (SCA2) is poorly understood, more so in the early stages of SCA2. In this study, we evaluated the microstructural integrity of the WM tracts with an emphasis on the nature of in vivo pathological involvement in early SCA2. MATERIALS AND METHODS:We evalu...

journal_title：Acta neurologica Scandinavica

authors： Stezin A,Bhardwaj S,Khokhar S,Hegde S,Jain S,Bharath RD,Saini J,Pal PK

更新日期：2020-10-08 00:00:00

abstract：:Rabbit antiserum to a citric acid extract of human skeletal muscle (CA) stained epithelial thymoma cells as well as skeletal muscle. Thymomas from two myasthenia gravis (MG) patients showing no circulating anti-CA antibodies prior to thymectomy were also stained by the antiserum. Thus, in these patients as well, the t...

journal_title：Acta neurologica Scandinavica

authors： Gilhus NE,Matre R,Aarli JA,Hofstad H,Thunold S

更新日期：1986-04-01 00:00:00

abstract：OBJECTIVES:To measure gait and postural stability by objective methods in spastic MS patients and to evaluate the effect of baclofen on gait and postural stability. PATIENTS AND METHODS:Fourteen spastic MS patients were examined in a placebo controlled double-blind, cross-over trial of oral baclofen treatment. The gai...

journal_title：Acta neurologica Scandinavica

authors： Orsnes GB,Sørensen PS,Larsen TK,Ravnborg M

更新日期：2000-04-01 00:00:00

abstract：:We tested the validity of a self-administered version of the minimal record of disability (MRD) for multiple sclerosis (MS) by measuring the agreement level between patients' self-assessment and neurologists' independent ratings. 96 MS patients and 4 neurologists took part in the experiment; the agreement level was me...

journal_title：Acta neurologica Scandinavica

authors： Solari A,Amato MP,Bergamaschi R,Logroscino G,Citterio A,Bochicchio D,Filippini G

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVES:Subjective feelings of memory decline are fairly common among the elderly. The causes of this are heterogeneous, and may be related to both affective and cognitive disorders. We attempted to explore the associations between subjective and cognitive measures. MATERIALS AND METHODS:Healthy subjects were studi...

journal_title：Acta neurologica Scandinavica

authors： Balash Y,Mordechovich M,Shabtai H,Merims D,Giladi N

更新日期：2010-03-01 00:00:00

abstract：:The use of high-dose polyclonal intravenous immunoglobulin (IVIG) in the treatment of autoimmune neurological diseases has expanded over the last decade. Based on controlled clinical trials IVIG can be considered currently as the first-line treatment in Guillain-Barré syndrome, chronic inflammatory demyelinating polyn...

journal_title：Acta neurologica Scandinavica

authors： Elovaara I,Hietaharju A

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The Multiple Sclerosis Functional Composite (MSFC) is a multidimensional measurement tool for multiple sclerosis (MS) including a measure of ambulation (Timed 25-foot Walk [TWT]), arm function (Nine-Hole Peg Test [9HPT]) and cognition (Paced Auditory Serial Addition Test [PASAT]). OBJECTIVES:To assess the r...

journal_title：Acta neurologica Scandinavica

authors： Rosti-Otajärvi E,Hämäläinen P,Koivisto K,Hokkanen L

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine the progression of cognitive dysfunction in primary Sjögren Syndrome (SS). METHODS:Twelve subjects with SS were compared with ten subjects with migraine and ten healthy controls on neuropsychological, mood and fatigue tests at baseline and 8 years later. RESULTS:At fol...

journal_title：Acta neurologica Scandinavica

authors： Martínez S,Cáceres C,Mataró M,Escudero D,Latorre P,Dávalos A

更新日期：2010-09-01 00:00:00

abstract：:Lumbar cerebrospinal fluid (CSF) from 30 cases of subacute sclerosing panencephalitis (SSPE) was studied for total protein and protein electrophoresis. Total CSF protein values were normal in almost all the cases, but the gamma-globulin was increased and had an oligoclonal morphology in all the cases. Absolute and rel...

journal_title：Acta neurologica Scandinavica

authors： Silva CA,Rio ME,Cruz C

更新日期：1981-04-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the role of transesophageal echocardiography in detecting the source of cerebral embolism in ischemic stroke patients and to evaluate the difference in occurrence of heart abnormalities in anterior and posterior circulation infarcts. MATERIAL AND METHODS:The study group i...

journal_title：Acta neurologica Scandinavica

authors： Mendel T,Pasierski T,Szwed H,Barańska-Gieruszczak M,Członkowska A

更新日期：1998-01-01 00:00:00

abstract：:Sympathetic denervation of the brain vessels was performed uni- or bilaterally in 13 adult rabbits, and cortical cold lesions were induced bilaterally 10-18 days afterwards. After a further 4-35 days the vascular and morphological changes in the lesion areas were studied histologically and with angiography. No differe...

journal_title：Acta neurologica Scandinavica

authors： West KA,Hassler O

更新日期：1976-09-01 00:00:00

abstract：:3 patients with the condition of "painful legs and moving toes" are reported. The etiology was unknown in 2 of them, but in 1 patient the symptoms were temporarily relieved by surgery for a lumbar herniated disc. The movements restarted 6 months after surgery. EMG studies showed near rhythmical muscle action potential...

journal_title：Acta neurologica Scandinavica

authors： Wulff CH

更新日期：1982-08-01 00:00:00

abstract：:We investigated the EEG frequency distribution by quantitative EEG (QEEG) in 28 children with type 1 diabetes and 28 age- and sex-matched control children. Among the diabetic children, 15 had experienced episodes of severe hypoglycemia (SH group) and 13 had not experienced such episodes (non-SH group). The EEG analysi...

journal_title：Acta neurologica Scandinavica

authors： Bjørgaas M,Sand T,Gimse R

更新日期：1996-06-01 00:00:00

abstract：:Twenty-seven patients with CT-scan-diagnosed arachnoid cysts in the middle cranial fossa were studied. Five (18%) presented with progressive symptoms related to raised intracranial pressure which had developed after minor trauma and secondary bleeding, 12 (44%) presented with non-progressive symptoms, and 10 (37%) exh...

journal_title：Acta neurologica Scandinavica

authors： Passero S,Filosomi G,Cioni R,Venturi C,Volpini B

更新日期：1990-08-01 00:00:00

abstract：UNLABELLED:Soluble APO-1 (sAPO-1) may prevent apoptosis of lymphocytes induced by activation of the APO-1/Fas receptor. OBJECTIVES:To determine sAPO-1 levels in the serum of multiple sclerosis (MS) patients and controls in order to investigate if abnormal lymphocyte apoptosis occurs in this disease. METHODS:Serum sam...

journal_title：Acta neurologica Scandinavica

authors： Bansil S,Holtz CR,Cook SD,Rohowsky-Kochan C

更新日期：1997-04-01 00:00:00