Painful legs and moving toes. A report of 3 cases with neurophysiological studies.

abstract：:Twenty patients with paralysis agitans took part in a double-blind, cross-over investigation of CB 154 (2-bromo-alpha-ergocryptine) and Madopar (L-Dopa + benserazid (a peripheral decarboxylase inhibitor), dose ratio 4:1). Each treatment phase lasted for 8 weeks. Modapar was found to be significantly superior to CB 154...

journal_title：Acta neurologica Scandinavica

authors： Gerlach J

更新日期：1976-03-01 00:00:00

abstract：:Variants in the EIF4G1 gene have been recently identified to be responsible for autosomal dominant PD (PARK18), but its role in the PD-related neurodegeneration is unclear. Several EIF4G1 mutation/variants were found to be associated with PD, and functional studies have suggested that these variants may impair the abi...

journal_title：Acta neurologica Scandinavica

authors： Deng H,Wu Y,Jankovic J

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVES:Interindividual variability in intestinal absorption and bioavailability might contribute to inadequate control of seizures under treatment with carbamazepine and phenytoin. We therefore correlated intestinal expression levels and genetics of CYP3A4, CYP2C9/19, MDR1 and MRP2 with dose requirement and plasma ...

journal_title：Acta neurologica Scandinavica

authors： Simon C,Stieger B,Kullak-Ublick GA,Fried M,Mueller S,Fritschy JM,Wieser HG,Pauli-Magnus C

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:To assess seizure control and tolerability of eslicarbazepine acetate (ESL) as adjunctive therapy to one baseline antiepileptic drug (AED), in adults with partial-onset seizures (POS) with or without secondary generalization. METHODS:Multicenter, non-interventional, prospective cohort study conducted between...

journal_title：Acta neurologica Scandinavica

authors： Chaves J,Breia P,Pimentel J,Pelejão R,Carvalho M,Mateus P,Grebe H,Mestre A,Fernandes H,Sousa R,Gala A

更新日期：2017-11-01 00:00:00

abstract：:We carried out a prospective study to determine the frequency and evolution of carpal tunnel syndrome (CTS) in patients with hyperthyroidism. An initial survey revealed CTS in 5% of these patients when hyperthyroidism was diagnosed. During the clinical and neurophysiologic follow-up for a two-year period, four more pa...

journal_title：Acta neurologica Scandinavica

authors： Roquer J,Cano JF

更新日期：1993-08-01 00:00:00

abstract：:This study investigated whether there are predictors for initial severity of ideomotor apraxia (IMA) in focal left-hemisphere vascular patients. One hundred and twenty-nine subjects were examined between 15 and 30 days post-onset. Twenty-five patients with bilateral lesions were also studied in order to delineate the ...

journal_title：Acta neurologica Scandinavica

authors： Basso A,Capitani E,Della Sala S,Laiacona M,Spinnler H

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:The quality-of-life (QoL) perception by Parkinson's disease (PD) patients and their caregivers (CG) has not been studied in depth. OBJECTIVE:To examine patient/proxy agreements on the PD QoL Questionnaire (PDQ-39), the Scale of Quality of Life of Care-Givers (SQLC) and the Multidimensional Caregiver Strain ...

journal_title：Acta neurologica Scandinavica

authors： Balash Y,Korczyn AD,Knaani J,Migirov AA,Gurevich T

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:We set to investigate the possible role of genes and environment in developing Alzheimer's disease (AD) in monozygotic twin pairs discordant for AD. METHODS:Three pairs of twins discordant for AD, who were enrolled in the Finnish Twin Cohort, were used in the study and compared with 13 controls. Gray matter...

journal_title：Acta neurologica Scandinavica

authors： Rossi R,Pievani M,Järvenpää T,Testa C,Koskenvuo M,Räihä I,Kaprio J,Frisoni GB,Rinne JO,Laakso MP

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:To clarify how chronic solvent abuse affects cognitive function using magnetic resonance imaging as an index of brain damage. MATERIAL AND METHODS:A total of 25 chronic solvent abusers underwent magnetic resonance imaging with quantitative neurometry and Wechsler Adult Intelligence Scales revised. RESULTS:T...

journal_title：Acta neurologica Scandinavica

authors： Yamanouchi N,Okada S,Kodama K,Sakamoto T,Sekine H,Hirai S,Murakami A,Komatsu N,Sato T

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Both pregnancy and high vitamin D concentration seem to generate a protective environment against multiple sclerosis (MS) relapses. Longitudinal case-control analysis of vitamin D concentrations during pregnancy and lactation of MS mothers is lacking. AIMS OF THE STUDY:To examine serum 25-hydroxyvitamin-D3 ...

journal_title：Acta neurologica Scandinavica

authors： Jalkanen A,Kauko T,Turpeinen U,Hämäläinen E,Airas L

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Cerebral small vessel disease (SVD) contributes to dementia and disability in the elderly, and may negatively affect stroke outcomes. We aimed to evaluate to what extent single features and global burden of SVD detected with magnetic resonance (MR) are associated with worse outcomes in patients with ischae...

journal_title：Acta neurologica Scandinavica

authors： Arba F,Inzitari D,Ali M,Warach SJ,Luby M,Lees KR,STIR\/VISTA Imaging Collaboration.

更新日期：2017-07-01 00:00:00

abstract：:Three patients at Stage II of subacute sclerosing panencephalitis (SSPE) were treated with semipurified alpha-interferon (IFN) using different combinations of intrathecal and intravenous routes: 1 x 10(6) IU of alpha-IFN were given every other day up to a total of 15 x 10(6) IU. Transient improvement of neurological s...

journal_title：Acta neurologica Scandinavica

authors： Maimone D,Grimaldi LM,Incorpora G,Biondi R,Sofia V,Mancuso GR,Siciliano L,Ruscica M,Pavone L

更新日期：1988-09-01 00:00:00

abstract：:EEG, regional cerebral blood flow (rCBF) and neuropathological autopsy data were studied in 17 patients with presenile dementia. RCBF was measured in 14 cases using the intra-arterial-133-Xenon clearance technique. The neuropathological study included semi-serial whole brain microscopical sections in which the severit...

journal_title：Acta neurologica Scandinavica

authors： Jóhannesson G,Brun A,Gustafson I,Ingvar DH

更新日期：1977-08-01 00:00:00

abstract：OBJECTIVES:To assess the possibility that the occurrence of seizures or the use of antiepileptic drug (AED) therapy might have influenced the rate of occurrence of volunteered histories of patient-recognized depression during pregnancy in women with epilepsy. MATERIALS AND METHODS:Analysis of data from 2039 pregnancie...

journal_title：Acta neurologica Scandinavica

authors： Vajda FJE,O'Brien TJ,Graham JE,Hitchcock AA,Mitchell J,Horgan D,Lander CM,Eadie MJ

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:Stimulation of the subthalamic nucleus (STN-DBS) is an established treatment with long-term beneficial effects on motor symptoms in patients with Parkinson's disease (PD). The long-term development of non-motor problems after STN-DBS is not fully understood. In this study, we have studied how non-motor probl...

journal_title：Acta neurologica Scandinavica

authors： Lilleeng B,Gjerstad M,Baardsen R,Dalen I,Larsen JP

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVES:To investigate the frequency of ECG abnormalities suggestive of myocardial ischaemia in patients with severe drug resistant epilepsy and without any indication of previous cardiac disease, assuming that these changes may be of significance for the group of epileptic patients with sudden unexpected death. MA...

journal_title：Acta neurologica Scandinavica

authors： Tigaran S,Rasmussen V,Dam M,Pedersen S,Høgenhaven H,Friberg B

更新日期：1997-08-01 00:00:00

abstract：OBJECTIVES:As part of a door-to-door survey of neurologic diseases, we investigated the prevalence of lumbosacral radiculopathy (LR) in two Sicilian municipalities (N = 14,540, as of November 1, 1987). MATERIAL & METHODS:During phase 1, we administered a brief screening instrument to subjects in the study population. ...

journal_title：Acta neurologica Scandinavica

authors： Savettieri G,Salemi G,Rocca WA,Meneghini F,D'Arpa A,Morgante L,Coraci MA,Reggio A,Grigoletto F,Di Perri R

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVES:To assess the effectiveness and safety/tolerability of eslicarbazepine acetate (ESL) in patients included in the Euro-Esli study who had focal seizures associated with post-stroke epilepsy (PSE). MATERIALS AND METHODS:Euro-Esli was a pooled analysis of 14 European clinical practice studies. Effectiveness as...

journal_title：Acta neurologica Scandinavica

authors： Sales F,Chaves J,McMurray R,Loureiro R,Fernandes H,Villanueva V

更新日期：2020-12-01 00:00:00

abstract：UNLABELLED:The basal ganglia are thought to be involved in the primary dystonias, largely because of the repeated demonstration of neuropathological changes in these nuclei in the secondary dystonias. A hyperactivity of a network involving basal ganglia has been suggested in experimental animal dystonia. To test this h...

journal_title：Acta neurologica Scandinavica

authors： Galardi G,Perani D,Grassi F,Bressi S,Amadio S,Antoni M,Comi GC,Canal N,Fazio F

更新日期：1996-09-01 00:00:00

abstract：:Forty-eight patients with a clinical diagnosis of Alzheimer's disease, 30 patients with cerebrovascular dementia, and 48 normal controls were assessed with a battery of neuropsychological tests designed to measure the following cognitive processes: orientation to time and place, memory, visual-perceptual and construct...

journal_title：Acta neurologica Scandinavica

authors： Villardita C

更新日期：1993-04-01 00:00:00

abstract：:Intractable seizure disorder is a clinical as well as a diagnostic problem. We evaluated the clinical role of extensive EEGs among patients (n = 64) considered to suffer from intractable paroxysmal neurologic symptoms. By reducing antiepileptic medication, ictal events were recorded in 89% of the cases. From the clini...

journal_title：Acta neurologica Scandinavica

authors： Nousiainen U,Suomalainen T,Mervaala E

更新日期：1992-03-01 00:00:00

abstract：OBJECTIVE:To investigate dopamine reuptake sites (dopamine transporter) in the caudate nucleus and putamen in narcolepsy. PATIENTS AND METHODS:Ten patients with narcolepsy and 15 controls were studied with positron emission tomography. A cocaine analogue [11C]-CFT was used as a radioligand. RESULTS:The uptake of[11C]...

journal_title：Acta neurologica Scandinavica

authors： Rinne JO,Hublin C,Någren K,Helenius H,Partinen M

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVES:Until now, the significance of plasma exchange (PE) as a treatment for steroid-unresponsive optic neuritis (ON) is still unclear because placebo-controlled and larger studies are missing. We report our experience with 23 patients treated by PE due to steroid-unresponsive ON. MATERIALS AND METHODS:Patients w...

journal_title：Acta neurologica Scandinavica

authors： Roesner S,Appel R,Gbadamosi J,Martin R,Heesen C

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:Although the recovery from Guillain-Barré syndrome (GBS) is good in most patients, some develop permanent severe disability or even die. Early predictors would increase the likelihood to identify patients at risk for poor outcome at the acute stage, allowing them intensified therapeutic intervention. MATERI...

journal_title：Acta neurologica Scandinavica

authors： Axelsson M,Sjögren M,Andersen O,Blennow K,Zetterberg H,Lycke J

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:To present clinical features at diagnosis for a large nationwide incident cohort of multiple sclerosis (MS) among those serving in the US military during the Gulf War era (GWE). MATERIALS & METHODS:Medical records and databases from the Department of Veterans Affairs (VA) for cases of MS with onset in or af...

journal_title：Acta neurologica Scandinavica

authors： Wallin MT,Culpepper WJ,Maloni H,Kurtzke JF

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:We describe 2 patients with epilepsy as an early manifestation of late onset metachromatic leukodystrophy (MLD). METHODS AND RESULTS:The first patient presented with epileptic seizures at the age of 34 years while neurological and cognitive abnormalities appeared later. MRI findings were compatible with leu...

journal_title：Acta neurologica Scandinavica

authors： Bostantjopoulou S,Katsarou Z,Michelakaki H,Kazis A

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVES:To investigate eventual differences between women and men with Parkinson's disease (PD) before and after surgery, with respect to clinical status, disability and health-related quality of life (HRQoL). MATERIAL AND METHODS:Twenty-four men and 14 women with PD received a total of 46 surgical procedures (pall...

journal_title：Acta neurologica Scandinavica

authors： Hariz GM,Lindberg M,Hariz MI,Bergenheim AT

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVES:We aimed to investigate associations between neuropsychological indices and normalized volumes of supratentorial structures, and the area of the corpus callosum. MATERIALS AND METHODS:We studied 40 patients with clinically definite MS, using 3D-acquired MRI (MPRAGE, Magnetization Prepared Rapid Acquisition ...

journal_title：Acta neurologica Scandinavica

authors： Edwards SG,Liu C,Blumhardt LD

更新日期：2001-10-01 00:00:00

abstract：:Two new components of the human SEP upon stimulation of the contralateral median nerve at the wrist have been identified. Such components have been called N16 and N17, according to their polarity and latency. N16 and N17, as well as the N14-P15 complex, are generated by separate subcortical dipoles. Particularly, they...

journal_title：Acta neurologica Scandinavica

authors： Abbruzzese M,Favale E,Leandri M,Ratto S

更新日期：1978-12-01 00:00:00

abstract：:Neuroacanthocytosis is a progressive multisystem disease with a wide range of symptoms. The involuntary movements mainly include chorea and orofaciolingual dyskinesias. The descriptive name of the disease refers to the presence of abnormal erythrocytes in peripheral blood. Two siblings are presented. One young female ...

journal_title：Acta neurologica Scandinavica

authors： Aasly J,Skandsen T,Rø M

更新日期：1999-11-01 00:00:00