Antiepileptic drugs and depression during pregnancy in women with epilepsy.

Abstract:

OBJECTIVES:To assess the possibility that the occurrence of seizures or the use of antiepileptic drug (AED) therapy might have influenced the rate of occurrence of volunteered histories of patient-recognized depression during pregnancy in women with epilepsy. MATERIALS AND METHODS:Analysis of data from 2039 pregnancies in the Raoul Wallenberg Australian Register of Antiepileptic Drugs in Pregnancy (APR) followed during pregnancy and to the end of the year after its end. RESULTS:Patient-recognized depression occurrence rates during pregnancy were a little lower rather than higher in seizure-affected than in seizure-free pregnancies (5.67% vs 6.41%), though higher in AED-treated than AED-untreated pregnancies (6.24% vs 5.26%; RR = 1.185, 95% CI 0.612, 2.295). Logistic regression analysis showed that carbamazepine dosage had a statistically significant relationship with a decreasing rate of patient-recognized depression occurring during pregnancy and topiramate dosage with an increasing rate. CONCLUSIONS:Carbamazepine and topiramate both have established potentials for causing teratogenesis, and it is possible that replacement of carbamazepine with a less teratogenic AED, for example levetiracetam, might result in any subsequent depression that occurs in pregnancy being inappropriately attributed to the newly introduced agent.

journal_name

Acta Neurol Scand

authors

Vajda FJE,O'Brien TJ,Graham JE,Hitchcock AA,Mitchell J,Horgan D,Lander CM,Eadie MJ

doi

10.1111/ane.13315

subject

Has Abstract

pub_date

2020-10-01 00:00:00

pages

350-355

issue

4

eissn

0001-6314

issn

1600-0404

journal_volume

142

pub_type

杂志文章
  • Cardiovascular and renin responses to head-up tilt tests in parkinsonism.

    abstract:OBJECTIVES:We investigated cardiovascular and renin responses to head-up tilt tests in patients with Parkinson's disease (PD), multiple system atrophy (MSA), and in controls to determine variables for the assignment of parkinsonism to the potential underlying neurologic condition. PATIENTS AND METHODS:Sequential chang...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1997.tb00270.x

    authors: Plaschke M,Schwarz J,Dahlheim H,Backmund H,Trenkwalder C

    更新日期:1997-10-01 00:00:00

  • Secretion of natriuretic peptides caused by an epileptic attack.

    abstract:OBJECTIVE:To describe clinical features of a patient with secretions of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) during an epileptic attack. PATIENT:A 65-year-old woman experienced frequent bouts of polyuria, pyrexia and general fatigue after several years of a cerebral contusion involving ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2002.01228.x

    authors: Obi T,Takatsu M,Konishi T,Mizoguchi K,Nishimura Y

    更新日期:2002-10-01 00:00:00

  • Altered blood-brain-barrier function in Alzheimer's disease?

    abstract::Alzheimer's disease (AD) and vascular dementia (VD) are the two most common causes of dementia. As yet, no definitive biological antemortem marker has been established for differential diagnosis of AD or VD. In this study, proteins of cerebrospinal fluid (CSF) from AD, VD and control patients were analyzed by two-dime...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1994.tb01660.x

    authors: Mattila KM,Pirttilä T,Blennow K,Wallin A,Viitanen M,Frey H

    更新日期:1994-03-01 00:00:00

  • In vivo microstructural white matter changes in early spinocerebellar ataxia 2.

    abstract:OBJECTIVE:White matter (WM) integrity of Spinocerebellar ataxia 2 (SCA2) is poorly understood, more so in the early stages of SCA2. In this study, we evaluated the microstructural integrity of the WM tracts with an emphasis on the nature of in vivo pathological involvement in early SCA2. MATERIALS AND METHODS:We evalu...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.13359

    authors: Stezin A,Bhardwaj S,Khokhar S,Hegde S,Jain S,Bharath RD,Saini J,Pal PK

    更新日期:2020-10-08 00:00:00

  • Diagnostic radioimmunoassay and DNA-analysis in Swedish and Japanese patients with familial amyloidotic polyneuropathy. Homozygosity for the TTR met30 gene.

    abstract::Eighteen Swedish patients with familial amyloidotic polyneuropathy were tested for the met30 mutation of the transthyretin (TTR) (prealbumin) gene by RFLP analysis of genomic DNA using the restriction enzyme NsiI. The results confirmed previous findings that the Swedish variant of familial polyneuropathy has the same ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1993.tb04090.x

    authors: Holmgren G,Lundgren E,Kangawa K,Kurihara T,Matsukura S,Matsuo H,Nakazato M,Steen L

    更新日期:1993-02-01 00:00:00

  • Season of birth and multiple sclerosis in Sweden.

    abstract:OBJECTIVE:To estimate the risk of multiple sclerosis (MS) by month of birth in Sweden. MATERIALS AND METHODS:Cases (n = 9361) were obtained from the Swedish MS Registry. All births in Sweden 1900-2007 served as controls (n = 12,116,853). The risk of MS was analyzed for each month of birth separately compared with birt...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2009.01181.x

    authors: Salzer J,Svenningsson A,Sundström P

    更新日期:2010-01-01 00:00:00

  • Accumulation of mercury in brainstem nuclei of mice after retrograde axonal transport.

    abstract::Adult mice were injected intramuscularly in the region of the vibrissae muscles on the left side of the nose with a small volume of mercuric chloride dissolved in distilled water. The animals were killed after 1-6 weeks and fixed by whole-body perfusion. Frozen sections were taken from different levels of the brain st...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1990.tb01612.x

    authors: Arvidson B

    更新日期:1990-10-01 00:00:00

  • Quality of life in Parkinson's disease: A gender-specific perspective.

    abstract:OBJECTIVES:The epidemiology, manifestations, and course of Parkinson's disease (PD) may differ in men and women. Assessments of severity of the illness and quality of life (QoL), and the burden on their caregivers (CG) may change as the disease advances. We determined gender differences in assessment by patients with P...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.13095

    authors: Balash Y,Korczyn AD,Migirov AA,Gurevich T

    更新日期:2019-07-01 00:00:00

  • Cerebrovascular disease in children.

    abstract::Stroke although rare in children, is an important cause of morbidity in the paediatric age group. Over a period of 8 years, 43 children (17 boys and 26 girls) in the age groups of 1-16 years (mean 8.02 yrs) presented with stroke which constituted 10% of all strokes in the young and 0.7% of all paediatric admissions. T...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1994.tb02716.x

    authors: Nagaraja D,Verma A,Taly AB,Kumar MV,Jayakumar PN

    更新日期:1994-10-01 00:00:00

  • The EIF4G1 gene and Parkinson's disease.

    abstract::Variants in the EIF4G1 gene have been recently identified to be responsible for autosomal dominant PD (PARK18), but its role in the PD-related neurodegeneration is unclear. Several EIF4G1 mutation/variants were found to be associated with PD, and functional studies have suggested that these variants may impair the abi...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/ane.12397

    authors: Deng H,Wu Y,Jankovic J

    更新日期:2015-08-01 00:00:00

  • General convulsions and rhabdomyolysis. Case reports.

    abstract::Two patients who developed rhabdomyolysis secondary to generalized seizures are presented. Minor traumas of skeletal muscles due to seizures may be associated with myoglobinuria and the development of acute renal failure. The diagnosis rhabdomyolysis may easily be confirmed by following serum creatine kinase. Myoglobi...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1989.tb03746.x

    authors: Os I,Lyngdal PT

    更新日期:1989-03-01 00:00:00

  • Interrater reliability of plaque morphology classification in patients with severe carotid artery stenosis.

    abstract:OBJECTIVE:Ultrasonographic assessment of carotid artery plaque morphology is widely used to identify patients at high risk for stroke. However, the reliability of plaque analysis in high-grade stenosis is uncertain. We determined the interrater reliability of sonographic plaque morphology analysis in patients with seve...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1999.tb00659.x

    authors: Hartmann A,Mohr JP,Thompson JL,Ramos O,Mast H

    更新日期:1999-01-01 00:00:00

  • Quality-of-life perception by Parkinson's disease patients and caregivers.

    abstract:BACKGROUND:The quality-of-life (QoL) perception by Parkinson's disease (PD) patients and their caregivers (CG) has not been studied in depth. OBJECTIVE:To examine patient/proxy agreements on the PD QoL Questionnaire (PDQ-39), the Scale of Quality of Life of Care-Givers (SQLC) and the Multidimensional Caregiver Strain ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12726

    authors: Balash Y,Korczyn AD,Knaani J,Migirov AA,Gurevich T

    更新日期:2017-08-01 00:00:00

  • Rufinamide in children and adults in routine clinical practice.

    abstract:OBJECTIVE:To explore the long-term effectiveness of rufinamide in managing Lennox-Gastaut Syndrome (LGS), other epileptic encephalopathies, and intractable focal epilepsies in adults and children in routine clinical practice. METHODS:A multicentre, retrospective chart review of patients prescribed adjunctive rufinamid...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,多中心研究

    doi:10.1111/ane.12572

    authors: Jaraba S,Santamarina E,Miró J,Toledo M,Molins A,Burcet J,Becerra JL,Raspall M,Pico G,Miravet E,Cano A,Fossas P,Fernández S,Falip M

    更新日期:2017-01-01 00:00:00

  • Computed tomography (CT) in late infantile metachromatic leucodystrophy.

    abstract::Computed tomographic features of 7 cases of the late infantile form of MLD confirmed by sural nerve biopsy are presented. Diffuse symmetrical white matter, low attenuation of the cerebral parenchyma was the common feature. Hypodensity of the temporal lobes and the cerebellar hemispheres are 2 features which have not b...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1989.tb03704.x

    authors: Jayakumar PN,Aroor SR,Jha RK,Arya BY

    更新日期:1989-01-01 00:00:00

  • Effect of memantine on CBF and CMRO2 in patients with early Parkinson's disease.

    abstract:OBJECTIVES:Parkinson's disease (PD) may be associated with increased energy metabolism in overactive regions of the basal ganglia. Therefore, we hypothesized that treatment with the N-methyl-d-aspartate receptor (NMDAR) antagonist memantine would decrease regional cerebral blood flow (rCBF) and oxygen metabolism in the...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0404.2007.00943.x

    authors: Borghammer P,Vafaee M,Ostergaard K,Rodell A,Bailey C,Cumming P

    更新日期:2008-05-01 00:00:00

  • Metabolism of histamine in myotonic dystrophy a dual pattern of inactivation of intestinal histamine.

    abstract::The catabolism of orally and subcutaneously administered 14C histamine was studied in myotonic dystrophy patients. No definite abnormalities were observed as for subcutaneously administered histamine. The catabolism of orally administered histamine followed two distinct patterns: In patients with a relatively low endo...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1977.tb01449.x

    authors: Sjaastad O,Sjaastad OV

    更新日期:1977-11-01 00:00:00

  • FPL 57787 and migraine prophylaxis. A double-blind cross-over study.

    abstract::In a double-blind cross-over trial with placebo, FPL 57787, a chromone derivate, was tested on 15 patients as a prophylactic against migraine. There was found to be no effect. ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0404.1979.tb02923.x

    authors: Koch-Henriksen N,Sehested P

    更新日期:1979-03-01 00:00:00

  • Cerebrospinal fluid investigations in multi-infarct dementia and senile dementia.

    abstract::Thirty-eight demented patients were clinically investigated and classified into a multi-infarct dementia (MID) and senile dementia (SD) group. Total protein, albumin, immunoglobulin G, agar gel electrophoretic protein and iso-electric focusing pattern were determined in CSF and serum as well as the lactate dehydrogena...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1981.tb04380.x

    authors: Wikkelsø C,Blomstrand C,Nordquist P

    更新日期:1981-07-01 00:00:00

  • EEG findings in diabetic patients with and without retinopathy.

    abstract:OBJECTIVES:We showed previously that temporal low-voltage irregular delta waves (TLID) on EEG are indicative of cerebrovascular dysfunction in its early stages. The present study was designed to determine whether the incidence of this finding is elevated in diabetics as compared to normal controls. METHODS:EEGs of 50 ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1998.tb00618.x

    authors: Inui K,Sannan H,Ota H,Uji Y,Nomura S,Kaige H,Kitayama I,Nomura J

    更新日期:1998-02-01 00:00:00

  • Expansion of a (CAG)n repeat region in a sporadic case of HD.

    abstract::The genetic mutation underlying Huntington's disease (HD) has been identified as an expansion and instability of a specific CAG repeat sequence in a gene on chromosome 4. A simple polymerase chain reaction assay has been used for the assessment of the (CAG)n expansion in a 72-year-old woman with typical HD symptoms, b...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1995.tb01026.x

    authors: Bozza A,Malagù S,Calzolari E,Novelletto A,Pavoni M,del Senno L

    更新日期:1995-08-01 00:00:00

  • Age at onset: the major determinant of outcome in Parkinson's disease.

    abstract::Factors at presentation which influenced the course of the disease and response to treatment were assessed in 125 de novo patients with Parkinson's disease. Ninety-eight patients were available for re-assessment at 5 years. Older patients presented earlier after the onset of symptoms, deteriorated more rapidly, and we...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1111/j.1600-0404.1995.tb00480.x

    authors: Hely MA,Morris JG,Reid WG,O'Sullivan DJ,Williamson PM,Broe GA,Adena MA

    更新日期:1995-12-01 00:00:00

  • Diffuse cerebral sclerosis, melanoderma and adrenal insufficiency (adreno-leukodystrophy).

    abstract::Two cases of adrenoleukodystrophy are described. The pathological picture was consistent with earlier observations about the disease with the difference that the brain tissue revealed material which stained metachromatically with toluidine blue and was insoluble in fat solvents. ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1978.tb02870.x

    authors: Hormia M

    更新日期:1978-08-01 00:00:00

  • Neuronal antinuclear antibody (anti-Hu) in paraneoplastic encephalomyelitis simulating acute polyneuritis.

    abstract::A patient with paraneoplastic encephalomyelitis (PEM) and small cell lung cancer had a clinical presentation of acute polyneuritis. The patient had an antibody (anti-Hu) restricted to nuclei of neurons identical to that reported in patients with subacute sensory neuronopathy and lung cancer. This finding further suppo...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1987.tb07928.x

    authors: Graus F,Elkon KB,Lloberes P,Ribalta T,Torres A,Ussetti P,Valls J,Obach J,Agusti-Vidal A

    更新日期:1987-04-01 00:00:00

  • Effect of baclofen on gait in spastic MS patients.

    abstract:OBJECTIVES:To measure gait and postural stability by objective methods in spastic MS patients and to evaluate the effect of baclofen on gait and postural stability. PATIENTS AND METHODS:Fourteen spastic MS patients were examined in a placebo controlled double-blind, cross-over trial of oral baclofen treatment. The gai...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1034/j.1600-0404.2000.101004244x./

    authors: Orsnes GB,Sørensen PS,Larsen TK,Ravnborg M

    更新日期:2000-04-01 00:00:00

  • The POEMS syndrome among Chinese: association with Castleman's disease and some immunological abnormalities.

    abstract::POEMS or Crow-Fukase syndrome is a multisystemic, clinically malignant disorder of obscure etiology. Peripheral neuropathy and plasma cell dyscrasia are central features. The authors now report 7 Chinese patients with this syndrome in which PCD or paraproteinemia were absent in 6, and 2 had a lymph node histology rese...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1989.tb03916.x

    authors: Thajeb P,Chee CY,Lo SF,Lee N

    更新日期:1989-12-01 00:00:00

  • Enzyme-linked immunosorbent assay for detection of antibodies to extractable muscle antigens in myasthenia gravis.

    abstract::A purified citric acid soluble extract from human skeletal muscle (AEMA) and a phosphate-buffered saline extract from rabbit muscle acetone powder (EMA) were used to coat polystyrene beads in an enzyme-linked immunosorbent assay (ELISA). From 54 patients with myasthenia gravis, positive results were observed in 14. Fi...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1986.tb04606.x

    authors: Viana VS,Bueno C,Marchiori PE,Oliveira RM,Assis JL,Scaff M,Cossermelli W

    更新日期:1986-06-01 00:00:00

  • Valproate in children with newly diagnosed idiopathic generalized epilepsy.

    abstract:OBJECTIVES:Sparse information on dose-response characteristics for initial antiepileptic drug monotherapy in children with idiopathic generalized epilepsy (IGE) is available. The aim of this study is to characterize the therapeutic dose of valproate in children with newly diagnosed IGE. MATERIALS AND METHODS:Effect of...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2009.01308.x

    authors: Holland KD,Monahan S,Morita D,Vartzelis G,Glauser TA

    更新日期:2010-03-01 00:00:00

  • Voxel-based morphometry study on monozygotic twins discordant for Alzheimer's disease.

    abstract:OBJECTIVES:We set to investigate the possible role of genes and environment in developing Alzheimer's disease (AD) in monozygotic twin pairs discordant for AD. METHODS:Three pairs of twins discordant for AD, who were enrolled in the Finnish Twin Cohort, were used in the study and compared with 13 controls. Gray matter...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12480

    authors: Rossi R,Pievani M,Järvenpää T,Testa C,Koskenvuo M,Räihä I,Kaprio J,Frisoni GB,Rinne JO,Laakso MP

    更新日期:2016-06-01 00:00:00

  • Familial recurrent cranial nerve palsies.

    abstract::Family cases of recurrent cranial nerve palsies are seldom reported. This paper presents a family with recurrent facial and ocular nerve palsies in 2 brothers. Their father and his sister had Bell's palsies. Examinations provided no explanation. Six previous reports of families with recurrent cranial nerve palsies are...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1988.tb03699.x

    authors: Sørensen TT

    更新日期:1988-12-01 00:00:00