The EIF4G1 gene and Parkinson's disease.

abstract：:From December 1976 through March 1982, 188 patients entered an open non-random study carried out on hospitalized patients with a history of transient ischemic attacks or amaurosis fugax. Ninety-two patients received peroral anticoagulants usually combined with heparin treatment during the first days of treatment, and ...

journal_title：Acta neurologica Scandinavica

authors： Eriksson SE

更新日期：1985-06-01 00:00:00

abstract：:While the association of spinal cord tumor and high-pressure hydrocephalus is well known, only 5 cases of spinal cord tumor associated with normotensive hydrocephalus have been reported. Two further cases are described here, discussing the possible pathophysiological mechanism. It is suggested that these patients go t...

journal_title：Acta neurologica Scandinavica

authors： Yarnitsky D,Honigman S,Hemli JA,Bental E

更新日期：1987-10-01 00:00:00

abstract：:We tested the validity of a self-administered version of the minimal record of disability (MRD) for multiple sclerosis (MS) by measuring the agreement level between patients' self-assessment and neurologists' independent ratings. 96 MS patients and 4 neurologists took part in the experiment; the agreement level was me...

journal_title：Acta neurologica Scandinavica

authors： Solari A,Amato MP,Bergamaschi R,Logroscino G,Citterio A,Bochicchio D,Filippini G

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVES:We examined whether the apolipoprotein E (ApoE) allele epsilon4 influences imaging findings in stroke as assessed by diffusion- (DWI) and perfusion-weighted (PWI) magnetic resonance imaging, and MR angiography (MRA). METHODS:Eight ApoE epsilon4 carriers and 15 non-carriers with acute ischemic stroke in the ...

journal_title：Acta neurologica Scandinavica

authors： Liu Y,Nuutinen J,Laakso MP,Karonen JO,Soimakallio S,Aronen HJ,Vanninen RL

更新日期：2006-11-01 00:00:00

abstract：:In this study levels of neuron-specific enolase (NSE), S-100 protein (S-100) and myelin basic protein (MBP) in cerebrospinal fluid (CSF) of children and adults with distinct neurological disorders were examined. A previous study from our department demonstrated age related reference values for these brain-specific pro...

journal_title：Acta neurologica Scandinavica

authors： Lamers KJ,van Engelen BG,Gabreëls FJ,Hommes OR,Borm GF,Wevers RA

更新日期：1995-09-01 00:00:00

abstract：:Lymphocyte transformation responses to measles, mumps, herpes simplex and parainfluenza virus antigens and purified protein derivative of tuberculin were determined in both 78 normal controls and 40 patients with multiple sclerosis, 16 of whom were studied serially. Patients with multiple sclerosis showed significantl...

journal_title：Acta neurologica Scandinavica

authors： Sagar HJ,Allonby ID,Hughes P

更新日期：1981-02-01 00:00:00

abstract：:Rats with different levels of blood glucose concentration were exposed to 10 min of complete brain ischemia achieved by compression of neck vessels by a pneumatic cuff. All normoglycemic rats survived the ischemic period and made the best clinical recovery. Hyperglycemic rats died within 12 h. Seizure activity was obs...

journal_title：Acta neurologica Scandinavica

authors： Siemkowicz E,Hansen AJ

更新日期：1978-07-01 00:00:00

abstract：:Serum levels of the soluble interleukin-2 receptor (sIL-2R), an indicator of T cell activation, were significantly elevated in chronic progressive MS (CPMS) patients, clinically stable MS patients and in patients with other neurological diseases (OND) as compared to healthy controls. Levels of sIL-2R in steroid treate...

journal_title：Acta neurologica Scandinavica

authors： Bansil S,Troiano R,Cook SD,Rohowsky-Kochan C

更新日期：1991-10-01 00:00:00

abstract：:The effect of methylprednisolone (MP) on neurologic recovery and spinal cord blood flow (SCBF) was investigated up to 4 days after a spinal cord compression injury in rats. The injury was produced at midthoracic level by applying a load of 35 g on a 2.2 x 5.0 mm compression plate for 5 min, which resulted in transient...

journal_title：Acta neurologica Scandinavica

authors： Holtz A,Nyström B,Gerdin B

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVES:There is paucity of information about the association of seizure severity and quality of life in people with epilepsy (PWE) in sub-Saharan Africa. We evaluated the relationship of seizure severity to health-related quality of life of patients with epilepsy being followed up in an outpatient neurology clinic ...

journal_title：Acta neurologica Scandinavica

authors： Adebayo PB,Akinyemi RO,Ogun SA,Ogunniyi A

更新日期：2014-02-01 00:00:00

abstract：:A case of transient global amnesia has been neuropsychologically assessed during the attack. Global involvement of any memory modalities and far-reaching retrograde amnesia were found. Follow-up retesting, 1 week and 6 months later, showed persistence of mild verbal memory impairment. ...

journal_title：Acta neurologica Scandinavica

authors： Caffarra P,Moretti G,Mazzucchi A,Parma M

更新日期：1981-01-01 00:00:00

abstract：:Sympathetic denervation of the brain vessels was performed uni- or bilaterally in 13 adult rabbits, and cortical cold lesions were induced bilaterally 10-18 days afterwards. After a further 4-35 days the vascular and morphological changes in the lesion areas were studied histologically and with angiography. No differe...

journal_title：Acta neurologica Scandinavica

authors： West KA,Hassler O

更新日期：1976-09-01 00:00:00

abstract：OBJECTIVES:Patients with multiple sclerosis were reported to harbour antibodies not only against proteins and glycoproteins but also against glycolipids, including sulfatide and galactosylceramide (GalCer), the two major glycosphingolipids of myelin. However, previous results were inconsistent concerning glycosphingoli...

journal_title：Acta neurologica Scandinavica

authors： Haghighi S,Lekman A,Nilsson S,Blomqvist M,Andersen O

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Idiopathic Parkinson's disease (IPD) is characterized by the clinical motor symptoms of hypokinesia, rigidity, and tremor. Apart from these motor symptoms, cognitive deficits often occur in IPD. The positive effect of cholinesterase inhibitors on cognitive deficits in IPD and findings of earlier molecular im...

journal_title：Acta neurologica Scandinavica

authors： Lorenz R,Samnick S,Dillmann U,Schiller M,Ong MF,Faßbender K,Buck A,Spiegel J

更新日期：2014-09-01 00:00:00

abstract：:Although intravenous (i.v.) heparin is widely used as the first line treatment for cerebral venous and sinus thrombosis (CVST), the most appropriate therapy for this disease is still controversial. We report 2 cases of CVST who were successfully treated by means of loco-regional thrombolysis with urokinase. In the fir...

journal_title：Acta neurologica Scandinavica

authors： Buccino G,Scoditti U,Pini M,Menozzi R,Piazza P,Zuccoli P,Mancia D

更新日期：2001-01-01 00:00:00

abstract：:Fifteen epileptic patients had their dose of anticonvulsant drugs changed twice, each time by 30-50 per cent of the initial medication. Before the dose change, the patients were given six especially adapted mental performance tests, which were designed to measure vigilance, reaction time and certain aspects of memory....

journal_title：Acta neurologica Scandinavica

authors： Dekaban AS,Lehman EJ

更新日期：1975-10-01 00:00:00

abstract：:A defined general population of 159,200 male and female native Swedes born in the period 1911-1940 from an urban catchment area of the then only general hospital, was followed over a decade (1970-79) with regard to in-patient hospitalization for all kinds of diagnoses. As a part of this population cohort study, multip...

journal_title：Acta neurologica Scandinavica

authors： Lindegård B

更新日期：1985-04-01 00:00:00

abstract：OBJECTIVE:Blepharoclonus (BLC) denotes a large amplitude, involuntary tremors of the orbicularis oculi muscles, observed during gentle closure of the eyelids. BLC may follow major head trauma. Four patients with Arnold-Chiari malformation (ACM) and BLC are described. MATERIALS AND METHODS:The first patient had facial ...

journal_title：Acta neurologica Scandinavica

authors： Jacome DE

更新日期：2001-08-01 00:00:00

abstract：:L-Deprenyl, a specific monoamine oxidase subtype B inhibitor, has been reported a valuable adjunct to conventional treatment of Parkinsonism. A double-blind cross-over controlled study was performed in 19 parkinsonian patients with on-off type problems. Five mg L-Deprenyl per day reduced the number of on-off episodes....

journal_title：Acta neurologica Scandinavica

authors： Brodersen P,Philbert A,Gulliksen G,Stigård A

更新日期：1985-06-01 00:00:00

abstract：:Neuroacanthocytosis is a progressive multisystem disease with a wide range of symptoms. The involuntary movements mainly include chorea and orofaciolingual dyskinesias. The descriptive name of the disease refers to the presence of abnormal erythrocytes in peripheral blood. Two siblings are presented. One young female ...

journal_title：Acta neurologica Scandinavica

authors： Aasly J,Skandsen T,Rø M

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVES:Myotonic dystrophy type 1 (DM1) is caused by large expansions of cytosine-thymine-guanine (CTG)-repeats in myotonic dystrophy protein kinase (DMPK)-gene. This gene is highly polymorphic in healthy individuals. It has been proposed that expanded alleles originated from the group of large sized normal alleles....

journal_title：Acta neurologica Scandinavica

authors： Culjković B,Stojković O,Vukosavić S,Savić D,Rakocevic V,Apostolski S,Romac S

更新日期：2002-01-01 00:00:00

abstract：:Cerebellar atrophy (CA) is a frequent finding in patients with chronic epilepsy. To find out whether the existence of CA has an influence on the tolerance of high-dose monotherapy with carbamazepine, we compared the lowest individual toxic serum levels in patients with complex focal seizures, with CA (n = 27) and with...

journal_title：Acta neurologica Scandinavica

authors： Specht U,Rohde M,May T,Schmidt RC,Meencke HJ,Wolf P

更新日期：1994-01-01 00:00:00

abstract：:Two cases of increased intracranial pressure associated with lumbar intraspinal tumours are reported. On the basis of protein investigations and constant flow infusion manometric tests, the pathophysiology of the increased intracranial pressure is discussed. It is demonstrated that protein macromolecules leak from the...

journal_title：Acta neurologica Scandinavica

authors： Borgesen SE,Sorensen SC,Olesen J,Gjerris F

更新日期：1977-09-01 00:00:00

abstract：:Gamma-aminobutyric acid (GABA) is the most important inhibitory transmitter, quantitatively, in the CNS. Evidence exists that decreased GABAergic neurotransmission may play a role in some forms of epilepsy. Consequently, manipulating the GABA system may be a therapeutic possibility in the treatment of this disease. In...

journal_title：Acta neurologica Scandinavica

authors： Gram L

更新日期：1988-10-01 00:00:00

abstract：:The clinical indications for temporal artery biopsy were explored using clinical decision analysis. The analysis indicated that biopsy is most useful in patients with a high likelihood of steroid side effects. It is nearly always useful when the pre-biopsy likelihood of temporal arteritis is low, but loses its value w...

journal_title：Acta neurologica Scandinavica

authors： Nadeau SE

更新日期：1988-08-01 00:00:00

abstract：OBJECTIVE:Assessment of usefulness of magnetoencephalography (MEG) as a novel non-invasive technique in the diagnostic evaluation of patients with recurrent seizures after unsuccessful epilepsy surgery. MATERIAL AND METHODS:Seventeen patients in whom epilepsy surgery had failed underwent reevaluation by means of MEG i...

journal_title：Acta neurologica Scandinavica

authors： Kirchberger K,Hummel C,Stefan H

更新日期：1998-07-01 00:00:00

abstract：:Preoperative treatment with glucocorticoids in patients with an intracranial tumour has been neurosurgical practice for more than 30 years. Recently, however, a less beneficial effect in patients with a meningeoma is reported. This study included 4 patients with a glioma, 4 with a metastasis and 5 with a meningeoma. A...

journal_title：Acta neurologica Scandinavica

authors： Skjoeth J,Bjerre PK

更新日期：1997-09-01 00:00:00

abstract：:The clinical features of multiple sclerosis (MS) in north-east Scotland have been examined along with an epidemiological study to determine the prevalence of the disease on 1st December, 1970. Patient information was collected from all available diagnostic indices, both retrospectively and prospectively from 1965. Eve...

journal_title：Acta neurologica Scandinavica

authors： Shepherd DI

更新日期：1979-10-01 00:00:00

abstract：:A microtechnique was established for the study of the limited numbers of cells available in CSF. The method allowed for the determination of the number of immunoglobulin-secreting cells (IgSC) as well as the quantitation of immunoglobulin or specific antibody secreted into the culture medium. Dose-response curves and ...

journal_title：Acta neurologica Scandinavica

authors： Sandberg M,Levinson AI,Zweiman B,Lisak RP

更新日期：1986-12-01 00:00:00

abstract：OBJECTIVES:To determine whether anti-GM1 antibodies are increased in Parkinson's disease (PD). METHODS:Serum immunoglobulin M (IgM) and IgG anti-GM1 antibodies were detected by enzyme-linked immunosorbent assay (ELISA) in 147 patients with PD and in 186 age-matched normal control subjects. Sera were assayed at initial...

journal_title：Acta neurologica Scandinavica

authors： Zappia M,Crescibene L,Bosco D,Arabia G,Nicoletti G,Bagalà A,Bastone L,Napoli ID,Caracciolo M,Bonavita S,Di Costanzo A,Gambardella A,Quattrone A

更新日期：2002-07-01 00:00:00