The EIF4G1 gene and Parkinson's disease.

abstract：:Previous reports concerning the treatment of symptoms deriving from prolapsed lumbar disc with systemic administration of the potent steroid dexamethasone, have shown favourable results. The present clinical study includes 39 patients with symptoms of prolapsed lumbar disc, treated in a controlled double-blind investi...

journal_title：Acta neurologica Scandinavica

authors： Hedeboe J,Buhl M,Ramsing P

更新日期：1982-01-01 00:00:00

abstract：:Status epilepticus (SE) describes an enduring epileptic state during which seizures are unremitting and tend to be self-perpetuating. We describe the clinical phases of generalized convulsive SE, impending SE, established SE, and subtle SE. We discuss the physiological and biochemical cascades which characterize self-...

journal_title：Acta neurologica Scandinavica

authors： Chen JW,Naylor DE,Wasterlain CG

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:To investigate whether the cardiac R-R interval variation (RRIV) is of value in differentiating patients with Parkinson's disease (PD) from multiple system atrophy (MSA). BACKGROUND:RRIV assessment is a simple procedure, reflecting mainly vagal efferent activity. Reduced RRIV was reported in MSA. METHODS:RR...

journal_title：Acta neurologica Scandinavica

authors： Gurevich TY,Groozman GB,Giladi N,Drory VE,Hausdorff JM,Korczyn AD

更新日期：2004-04-01 00:00:00

abstract：:Myotonic dystrophy seems to have a hypometabolism of non-thyroid origin. The hypometabolism could hypothetically be caused by : 1) reduction in muscle mass, 2) hydrocephalus ex vacuo, an integral part of the disorder, or 3) the basic disease process itself. Possibility 2) was explored by determining basal metabolic ra...

journal_title：Acta neurologica Scandinavica

authors： Hidle I,Sjaastad O

更新日期：1976-03-01 00:00:00

abstract：OBJECTIVE:To clarify the relationship between mitochondrial DNA (mtDNA) sequence variations and phenotypes in patients with A3243G mutation. MATERIALS AND METHODS:We studied whole mtDNA sequences in two families with A3243G mutation and characteristic clinical features. Two brothers in Family 1 had shown thiamine defi...

journal_title：Acta neurologica Scandinavica

authors： Morovvati S,Nakagawa M,Sato Y,Hamada K,Higuchi I,Osame M

更新日期：2002-08-01 00:00:00

abstract：:One cause of ischemic brain injury is free radical formation during recirculation. Allopurinol inhibits xanthine oxidase, an important source of free oxygen radicals. It is known that allopurinol pre-treatment has a protective action during cerebral ischemia. In the present study we exposed slices from the rat hippoca...

journal_title：Acta neurologica Scandinavica

authors： Hegstad E,Berg-Johnsen J,Langmoen IA

更新日期：1991-05-01 00:00:00

abstract：OBJECTIVES:Myotonic dystrophy type 1 (DM1) is caused by large expansions of cytosine-thymine-guanine (CTG)-repeats in myotonic dystrophy protein kinase (DMPK)-gene. This gene is highly polymorphic in healthy individuals. It has been proposed that expanded alleles originated from the group of large sized normal alleles....

journal_title：Acta neurologica Scandinavica

authors： Culjković B,Stojković O,Vukosavić S,Savić D,Rakocevic V,Apostolski S,Romac S

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Neuropsychiatric symptoms are common in Parkinson's disease and may precede onset of motor symptoms. They are also known to increase caregiver's burden. OBJECTIVE:The aim of this study was to assess neuropsychiatric symptoms in a cohort of Nigerian patients with idiopathic Parkinson's disease and compare wi...

journal_title：Acta neurologica Scandinavica

authors： Ojagbemi AA,Akinyemi RO,Baiyewu O

更新日期：2013-07-01 00:00:00

abstract：:It has been suggested that nitric oxide could be implicated in the neuronal degeneration of substantia nigra compacta in patients with Parkinson's disease. Recently, it has been reported decreased CSF nitrate levels (oxidation product that provides an indirect estimation of nitric oxide) in Parkinson's disease patient...

journal_title：Acta neurologica Scandinavica

authors： Molina JA,Jiménez-Jiménez FJ,Navarro JA,Vargas C,Gómez P,Benito-León J,Ortí-Pareja M,Cisneros E,Arenas J

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:To explore the relationship between motor subtypes and drooling, and other risk factors associated with drooling in a large cohort of Chinese patients with Parkinson's disease (PD). METHODS:A total of 586 PD patients were enrolled in this study. Unified Parkinson's disease rating scale (UPDRS) and Hoehn & Ya...

journal_title：Acta neurologica Scandinavica

authors： Mao CJ,Xiong YT,Wang F,Yang YP,Yuan W,Zhu C,Chen J,Liu CF

更新日期：2018-05-01 00:00:00

abstract：:Further studies pm yjr rofr,op;phu pg ,i;yo;r dv;rtpdod (MS) IN Finland were carried out in three different types of geographical unit: in counties, combined clerical districts, and single clerical district. For longitudinal studies, the prevalence of MS by present domicile was compared to that by place of birth, and ...

journal_title：Acta neurologica Scandinavica

authors： Wikström J,Palo J

更新日期：1975-02-01 00:00:00

abstract：:Juvenile myoclonic epilepsy (JME) is a special syndrome within the primary generalized epilepsies which is characterized clinically by irregular jerks of shoulders and arms (so-called impulsive petit mal) after awakening and electroencephalographically by bilateral-synchronous 4-6/s spike-wave complexes, often in the ...

journal_title：Acta neurologica Scandinavica

authors： Janz D

更新日期：1985-11-01 00:00:00

abstract：AIMS:To conduct a psychometric analysis to determine the adequacy of instruments that measure cognition in Alzheimer's disease trials. BACKGROUND:Both the Alzheimer's Disease Assessment Scale - Cognition (ADAS-Cog) and the Neuropsychological Test Battery (NTB) are validated outcome measures for clinical trials in Alzh...

journal_title：Acta neurologica Scandinavica

authors： Karin A,Hannesdottir K,Jaeger J,Annas P,Segerdahl M,Karlsson P,Sjögren N,von Rosen T,Miller F

更新日期：2014-02-01 00:00:00

abstract：:An epidemiological survey of multiple sclerosis was carried out in the western part of Poland. The estimated prevalence rate on December 31, 1981 was compared with that established on the same territory on January 1, 1965. The disease was less frequent in 1981. The prevalence rate for definite cases was only 42.87 ver...

journal_title：Acta neurologica Scandinavica

authors： Wender M,Pruchnik-Grabowska D,Hertmanowska H,Kowal P,Zielińska M,Namysł I,Marcinkowski J

更新日期：1985-08-01 00:00:00

abstract：OBJECTIVES:It was shown previously that low-Mg2+-induced epileptiform activity in rat entorhinal cortex slices changes with time from a pattern of serial seizure-like events (SLEs) to a state of continuously recurring epileptiform activity. Valproic acid blocked the early SLEs but not the late activity. It was proposed...

journal_title：Acta neurologica Scandinavica

authors： Dreier JP,Zhang CL,Heinemann U

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVES:To examine through a meta-analysis whether a treatment strategy of surgery plus the routine medical management saves lives and reduces disability in survivors of primary supratentorial intracerebral hematoma compared to routine medical management alone. MATERIAL AND METHODS:Computerized bibliographic search...

journal_title：Acta neurologica Scandinavica

authors： Prasad K,Browman G,Srivastava A,Menon G

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVES:Strokes represent the most common etiology of epilepsy in patients over the age of 60 years, with an incidence of 2-4% occurring in different studies. MATERIALS AND METHODS:In this observational study, 1,428 patients were included who had stroke and were admitted to our Stroke Unit between the years 1996 an...

journal_title：Acta neurologica Scandinavica

authors： Benbir G,Ince B,Bozluolcay M

更新日期：2006-07-01 00:00:00

abstract：:3-methoxy-4-hydroxyphenylglycol (MHPG) and 5-hydroxyindoleacetic acid (5-HIAA) as well as homovanillic acid (HVA) and cyclic AMP were estimated in the morning urine of 41 drug-free parkinsonian patients and 25 hospitalized controls. In 29 patients, the estimations were repeated after 2 weeks treatment with L-dopa plus...

journal_title：Acta neurologica Scandinavica

authors： Markianos M,Hadjikonstantinou M,Bistolaki E

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:Persons who have suffered from acute poliomyelitis may decades later experience reduction of balance and gait capacity due to muscle weakness, fatigue and/or pain. This may affect the activity level in daily life of these persons. AIMS OF THE STUDY:The aim of this study was to describe observer assessed and...

journal_title：Acta neurologica Scandinavica

authors： Lehmann K,Sunnerhagen KS,Willén C

更新日期：2006-01-01 00:00:00

abstract：:Three patients are described with muscular dystrophy and contractures. Although this disorder bears similarities to Emery-Dreifuss disease and variants previously described, absence of cardiomyopathy is a distinguishing feature. Electrodiagnostic testing and muscle biopsy are consistent with a myopathy. An autosomal d...

journal_title：Acta neurologica Scandinavica

authors： Bailey RO,Dentinger MP,Toms ME,Hans MB

更新日期：1986-04-01 00:00:00

abstract：OBJECTIVES:To assess the correlation of diffusion-weighted (DWI) and perfusion-weighted imaging (PWI) findings with the severity of acute neurologic deficit and their ability to predict short and long-term clinical outcomes of stroke. The ability of DWI and PWI to predict the outcome was compared with the ability of cl...

journal_title：Acta neurologica Scandinavica

authors： Nuutinen J,Liu Y,Laakso MP,Karonen JO,Roivainen R,Vanninen RL,Partanen K,Østergaard L,Sivenius J,Aronen HJ

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that status epilepticus can lead to neuronal injury. However, the effect of a small number of isolated seizures is uncertain. METHODS:We used structural MRI and neuropathology to study the effects of isolated seizures induced by kainic acid (KA), (RS)-2-amino-3-(3-hydroxy-5-tert-...

journal_title：Acta neurologica Scandinavica

authors： Acosta MT,Munashinge J,Zhang L,Guerron DA,Vortmeyer A,Theodore WH

更新日期：2012-01-01 00:00:00

abstract：:Acute disseminated encephalomyelitis (ADEM) is an acute monophasic inflammatory and demyelinating disease of the central nervous system (CNS) occurring days to weeks after a virus infection or vaccination. Nephropathia epidemica (NE) is a haemorrhagic fever with renal syndrome caused by Puumala virus, with endemic reg...

journal_title：Acta neurologica Scandinavica

authors： Toivanen AL,Valanne L,Tatlisumak T

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVES:To address the relationship between years lived with a disability (YLDs), prevalence and cost of neurological diseases, and to test whether there is a European North-South gradient for national health expenditure, disability, costs and prevalence of neurological diseases. MATERIALS AND METHODS:Information o...

journal_title：Acta neurologica Scandinavica

authors： Raggi A,Leonardi M

更新日期：2015-07-01 00:00:00

abstract：:We report a case of acute Wernicke encephalopathy (WE) in which apparent diffusion coefficient maps showed areas of increased diffusion in the bilateral medial thalami that corresponded to the hyperintense lesions on T2-weighted imaging. The hyperintense lesions on T2-weighted imaging disappeared with full recovery fr...

journal_title：Acta neurologica Scandinavica

authors： Oka M,Terae S,Kobayashi R,Kudoh K,Chu BC,Kaneko K,Yoshida M,Kaneda M,Suzuki Y,Miyasaka K

更新日期：2001-09-01 00:00:00

abstract：:Patients with prior poliomyelitis with paresis and excessive use (n = 8) and low use (n = 6) of residual anterior tibial motor units (MUs) during walking were subjected to muscle biopsy of the anterior tibial muscle (TA). Antibodies directed against cytoskeletal proteins, spectrin and desmin, and against Leu-19, a myo...

journal_title：Acta neurologica Scandinavica

authors： Borg K,Edström L

更新日期：1993-02-01 00:00:00

abstract：INTRODUCTION:Cortical blindness, a rare form of cyclosporine (CSA) neurotoxicity, has previously been described in only nine bone marrow transplant (BMT) recipients. METHODS:Our institution averages 35 allogeneic BMT's per year. In the past year we have seen two women with reversible cortical blindness secondary to CS...

journal_title：Acta neurologica Scandinavica

authors： Edwards LL,Wszolek ZK,Normand MM

更新日期：1996-11-01 00:00:00

abstract：:A prospective electrophysiological study of phrenic nerve was performed in 59 subjects undergoing open-heart surgery. The nerve was stimulated percutaneously at the neck and the diaphragmatic response was recorded with surface electrodes placed over the 8th intercostal space. The latency, amplitude, duration and area ...

journal_title：Acta neurologica Scandinavica

authors： Chroni E,Patel RL,Taub N,Venn GE,Howard RS,Panayiotopoulos CP

更新日期：1995-04-01 00:00:00

abstract：:Genetic investigation of 74 patients with temporal lobe epilepsy, resistant to medication, who underwent unilateral temporal lobectomy 1960-1969. Thirty per cent had a positive family history of epilepsy; 49 per cent of other neurological diseases; and 46 per cent of major psychiatric disorders. Neither of the genetic...

journal_title：Acta neurologica Scandinavica

authors： Jensen I

更新日期：1975-11-01 00:00:00

abstract：:POEMS or Crow-Fukase syndrome is a multisystemic, clinically malignant disorder of obscure etiology. Peripheral neuropathy and plasma cell dyscrasia are central features. The authors now report 7 Chinese patients with this syndrome in which PCD or paraproteinemia were absent in 6, and 2 had a lymph node histology rese...

journal_title：Acta neurologica Scandinavica

authors： Thajeb P,Chee CY,Lo SF,Lee N

更新日期：1989-12-01 00:00:00