The effect of L-Deprenyl on on-off phenomena in Parkinson's disease.

Abstract:

:L-Deprenyl, a specific monoamine oxidase subtype B inhibitor, has been reported a valuable adjunct to conventional treatment of Parkinsonism. A double-blind cross-over controlled study was performed in 19 parkinsonian patients with on-off type problems. Five mg L-Deprenyl per day reduced the number of on-off episodes. Side effects such as hyperkinesias, vivid dreams, dizziness with diaphoresis were frequent. Severe side effects such as nightmares, postural hypotension, confusion, and dizziness with headaches necessitated discontinuation of the drug in 4 patients. L-Deprenyl was of limited value in this group of patients with longstanding Parkinsonism.

journal_name

Acta Neurol Scand

authors

Brodersen P,Philbert A,Gulliksen G,Stigård A

doi

10.1111/j.1600-0404.1985.tb03233.x

subject

Has Abstract

pub_date

1985-06-01 00:00:00

pages

494-7

issue

6

eissn

0001-6314

issn

1600-0404

journal_volume

71

pub_type

临床试验,杂志文章
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    doi:10.1111/j.1600-0404.1985.tb03178.x

    authors: Santavuori P,Westermarck T,Rapola J,Pohja P,Moren R,Lappi M,Vuonnala U

    更新日期:1985-02-01 00:00:00

  • Computed tomography (CT) in late infantile metachromatic leucodystrophy.

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    pub_type: 杂志文章

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    更新日期:1989-01-01 00:00:00

  • Capsular infarcts: location, size and etiology of pure motor hemiparesis, sensorimotor stroke and ataxic hemiparesis.

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    doi:10.1111/j.1600-0404.1993.tb04233.x

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    更新日期:1993-10-01 00:00:00

  • Comparison between agarose gel electrophoresis and isoelectric focusing of CSF for demonstration of oligoclonal immunoglobulin bands in neurological disorders.

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    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1978.tb02874.x

    authors: Laurenzi MA,Link H

    更新日期:1978-09-01 00:00:00

  • Valproate in children with newly diagnosed idiopathic generalized epilepsy.

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    更新日期:2010-03-01 00:00:00

  • Impact of five SNPs in dopamine-related genes on executive function.

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2012.01673.x

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    更新日期:2013-01-01 00:00:00

  • Efficacy of a soft hand brace and a wrist splint for carpal tunnel syndrome: a randomized controlled study.

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    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0404.2008.01072.x

    authors: De Angelis MV,Pierfelice F,Di Giovanni P,Staniscia T,Uncini A

    更新日期:2009-01-01 00:00:00

  • Vaccine-associated contact paralytic poliomyelitis with atypical neurological presentation.

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1987.tb03569.x

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    更新日期:1987-09-01 00:00:00

  • Temporal lobe "plus" epilepsy associated with oligodendroglial hyperplasia (MOGHE).

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    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.13142

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    pub_type: 杂志文章

    doi:10.1111/ane.12948

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    更新日期:2018-09-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1994.tb01684.x

    authors: Ylitalo V,Hagberg BA

    更新日期:1994-04-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2016-02-01 00:00:00

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    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1600-0404.1996.tb00035.x

    authors: Fredrikson S

    更新日期:1996-07-01 00:00:00

  • Pediatric frontal lobe epilepsy: white matter abnormalities and cognitive impairment.

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    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12183

    authors: Braakman HM,Vaessen MJ,Jansen JF,Debeij-van Hall MH,de Louw A,Hofman PA,Vles JS,Aldenkamp AP,Backes WH

    更新日期:2014-04-01 00:00:00

  • Regional spinal cord blood flow in the rabbit, cat and monkey.

    abstract::Regional blood flow in the spinal cord was measured in rabbits, cats and monkeys with radioactively labelled microspheres. The reproducibility of the method was tested in rabbits by 3 consecutive determinations with differently labelled microspheres within the different cord regions, and was found to be good. In all 3...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1984.tb00828.x

    authors: Nyström B,Stjernschantz J,Smedegård G

    更新日期:1984-10-01 00:00:00

  • M-wave analysis and passive tilt in patients with different degrees of carotid artery disease.

    abstract:BACKGROUND AND PURPOSE:Carotid artery disease (CAD) is able to critically impair cerebral autoregulation which increases the risk for stroke. As therapeutic strategy largely depends on the degree of CAD, we investigated whether this gradation is also related to significant changes in autoregulatory capacity. We applied...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2003.00210.x

    authors: Haubrich C,Klemm A,Diehl RR,Möller-Hartmann W,Klötzsch C

    更新日期:2004-03-01 00:00:00

  • Hereditary spastic paraplegia with neurogenic bladder disturbances and syndactylia.

    abstract::The present paper reports a family settled in the northern part of Norway, with a hereditary neurological disorder consisting clinically of spastic paraplegia associated with neurogenic bladder disturbances and syndactylia. Nine out of 22 members in three generations exhibit these clinical features. The bladder distur...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1980.tb02993.x

    authors: Opjordsmoen S,Nyberg-Hansen R

    更新日期:1980-01-01 00:00:00

  • An association of human T-cell lymphotropic virus type I infection with vascular dementia.

    abstract::Subjects ranging in age from 50 to 89 years old, either with or without dementia were studied by both ELISA for anti-human T-cell lymphotropic virus type I (HTLV-I) gag 100-130 antibody and by cranial CT in order to clarify the relationship between HTLV-I infection and dementia. The frequency of anti-HTLV-I antibody w...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1997.tb00288.x

    authors: Kira J,Hamada T,Kawano Y,Okayama M,Yamasaki K

    更新日期:1997-11-01 00:00:00

  • Efficacy of group cognitive rehabilitation therapy in multiple sclerosis.

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    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/ane.12904

    authors: Mani A,Chohedri E,Ravanfar P,Mowla A,Nikseresht A

    更新日期:2018-06-01 00:00:00

  • Screening of patients with hereditary spastic paraparesis and Addison's disease for adrenoleukodystrophy/adrenomyeloneuropathy.

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    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1992.tb04015.x

    authors: Holmberg BH,Hägg E,Duchek M,Hagenfeldt L

    更新日期:1992-02-01 00:00:00

  • Nicotinic α4β2 acetylcholine receptors and cognitive function in Parkinson's disease.

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    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12259

    authors: Lorenz R,Samnick S,Dillmann U,Schiller M,Ong MF,Faßbender K,Buck A,Spiegel J

    更新日期:2014-09-01 00:00:00

  • Blepharoclonus and Arnold-Chiari malformation.

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    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2001.104002113.x

    authors: Jacome DE

    更新日期:2001-08-01 00:00:00

  • Interictal brain 99Tc-HM-PAO SPECT hypoperfusion in patients with unstable partial epilepsy and normal CT.

    abstract::Brain perfusion was studied interictally with 99mTc-HM-PAO SPECT in 47 adult patients with partial epilepsy and normal brain CT. Epilepsy was classified as secondarily generalized in 24 patients, as complex partial in 17 patients and as simple partial in 6 patients. In 24 patients good seizure control was not achieved...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1992.tb05486.x

    authors: Launes J,Iivanainen M,Salmi T,Nikkinen P,Lindroth L,Liewendahl K

    更新日期:1992-12-01 00:00:00

  • Propranolol (Inderal) and clonidine (Catapressan) in the prophylactic treatment of migraine. A comparative trial.

    abstract::Twenty-one patients continued a double-blind crossover study to compare the prophylactic effect on migraine of propranolol and clonidine. The daily dosage of propranolol and clonidine was 160 mg and 100 microgram, respectively. Statistical analysis did not show any significant difference between the two drugs in respe...

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    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0404.1980.tb01504.x

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  • Postoperative multichannel magnetoencephalography in patients with recurrent seizures after epilepsy surgery.

    abstract:OBJECTIVE:Assessment of usefulness of magnetoencephalography (MEG) as a novel non-invasive technique in the diagnostic evaluation of patients with recurrent seizures after unsuccessful epilepsy surgery. MATERIAL AND METHODS:Seventeen patients in whom epilepsy surgery had failed underwent reevaluation by means of MEG i...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1998.tb07370.x

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    更新日期:1998-07-01 00:00:00

  • Diagnosis of and treatment for symptomatic carotid stenosis: an updated review.

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    pub_type: 杂志文章,评审

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2004.00316.x

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  • Prevalence of lumbosacral radiculopathy in two Sicilian municipalities. Sicilian Neuro-Epidemiologic Study (SNES) Group.

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1996.tb00027.x

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2009.01293.x

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