Abstract：
BACKGROUND:Major neurological improvement (MNI) at 24 hours represents a marker of early recanalization in ischaemic stroke. Although low body temperature is considered neuroprotective in cerebral ischaemia, some studies have suggested that higher body temperature may promote clot lysis in the acute phase of ischaemic stroke. We hypothesized that higher body temperature was associated with MNI in severe stroke patients treated with tPA, suggesting a beneficial effect of higher body temperature on clot lysis and recanalization. METHODS:Patients with ischaemic stroke or transient ischaemic attack (TIA) treated with tPA between February 2006 and August 2012 were prospectively included and retrospectively analysed. Body temperature was measured upon admission. MNI was defined by a ≥8 point improvement in NIHSS score at 24 hours as compared to NIHSS score on admission. No significant improvement (no-MNI) was defined by either an increase in NIHSS score or a decrease of ≤2 points at 24 hours in patients with an admission NIHSS score of ≥8. RESULTS:Of the 2351 patients admitted with ischaemic stroke or TIA, 347 patients (14.8%) were treated with tPA. A total of 32 patients (9.2%) had MNI and 56 patients (16.1%) had no-MNI. Patients with MNI had higher body temperatures compared with patients with no-MNI (36.7°C vs 36.3°C, P = 0.004). Higher body temperature was independently associated with MNI when adjusted for confounders (OR 5.16, P = 0.003). CONCLUSION:Higher body temperature was independently associated with MNI in severe ischaemic stroke patients treated with tPA. This may suggest a beneficial effect of higher body temperature on clot lysis and recanalization.
journal_name
Acta Neurol Scandjournal_title
Acta neurologica Scandinavicaauthors
Kvistad CE,Thomassen L,Waje-Andreassen U,Logallo N,Naess Hdoi
10.1111/ane.12184subject
Has Abstractpub_date
2014-05-01 00:00:00pages
325-9issue
5eissn
0001-6314issn
1600-0404journal_volume
129pub_type
杂志文章abstract：BACKGROUND:Presence of mild cognitive impairment (MCI) as a predictor for Parkinson's disease dementia (PDD) has been discussed from a clinical perspective. Recently, a Movement Disorder Society (MDS) commissioned Task Force published guidelines for PD-MCI. However, long-term follow-ups of the PD-MCI guidelines for the...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/ane.12375
更新日期：2015-08-01 00:00:00
abstract：:50 open-heart patients were investigated using simultaneous clinical, electroencephalographical (EEG) and neuropsychological evaluation in order to assess the possibilities of predicting the postoperative outcome with preoperative measures. The presence of one or more of the following indices was prognostically unfavo...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.1982.tb04535.x
更新日期：1982-12-01 00:00:00
abstract：OBJECTIVE:To assess seizure control and tolerability of eslicarbazepine acetate (ESL) as adjunctive therapy to one baseline antiepileptic drug (AED), in adults with partial-onset seizures (POS) with or without secondary generalization. METHODS:Multicenter, non-interventional, prospective cohort study conducted between...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/ane.12734
更新日期：2017-11-01 00:00:00
abstract：:Febrile seizures occurred in 14 of 155 (9%) out-patients with complex partial seizures. Twelve patients had prolonged or recurrent febrile seizures, convulsive status epilepticus or a transient postictal neurological deficit. Febrile seizures were associated with perinatal abnormalities, an earlier onset of epilepsy a...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.1985.tb01550.x
更新日期：1985-07-01 00:00:00
abstract：OBJECTIVES:We performed nerve conduction and needle electromyographic tests in 29 patients with spastic cerebral palsy (SCP) and severe limb deformities. Nerve conduction abnormalities were detected in 32 of 400 sensory or motor nerves, while 11 of 29 patients (37.9%) showed abnormal nerve conduction, indicating one or...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.2005.00468.x
更新日期：2005-09-01 00:00:00
abstract：OBJECTIVE:To study mathematical deficits in the early stages of Alzheimer's disease (AD). METHODS:Sixty-eight patients with mild AD and 242 normal controls (NC) received a standardized battery (EC 301-R) assessing number processing and calculation abilities. AD patients also received testing for language, memory, visu...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.1999.tb07339.x
更新日期：1999-03-01 00:00:00
abstract：:The preventive and suppressive effects of methylprednisolone (MP) were investigated in 22 rabbits immunized with peripheral nerve myelin. Cellular reactivity to bovine P2 protein (P2) and anti-P2 antibody were also examined serially in these animals, using the lymphocyte proliferation test or enzyme-linked immunosorbe...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.1988.tb05942.x
更新日期：1988-06-01 00:00:00
abstract：OBJECTIVES:To examine differences in cerebrovascular reactivity between multi-infarct and Alzheimer types of dementia. PATIENTS AND METHODS:Using transcranial Doppler, measurements of flow velocity in the middle cerebral arteries during apnea, thumb-to-finger opposition and verbal and design discrimination tasks were ...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.1998.tb05969.x
更新日期：1998-06-01 00:00:00
abstract：:Amino acid concentrations in plasma of patients with Huntington's disease (HD) were determined in 16 patients and 21 age- and sex-matched healthy controls. Alanine and isoleucine were significantly decreased in HD plasma whereas arginine, histidine, leucine, lysine, ornithine, proline, serine, threonine, tyrosine, and...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.1995.tb00438.x
更新日期：1995-03-01 00:00:00
abstract：OBJECTIVE:White blood cells might have a pathogenetic role in ischemic vascular conditions. Several studies have suggested that increased adhesiveness of these cells could contribute to such a damage. The present study was undertaken in order to examine the adhesive properties of leukocytes in the peripheral blood of p...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：1997-08-01 00:00:00
abstract：:A defined general population of 159,200 male and female native Swedes born in the period 1911-1940 from an urban catchment area of the then only general hospital, was followed over a decade (1970-79) with regard to in-patient hospitalization for all kinds of diagnoses. As a part of this population cohort study, multip...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：1985-04-01 00:00:00
abstract：:Multiple sclerosis (MS) is associated with autoimmune disorders (AIDs) in individual patients, and limited data suggest a possible familial association of MS and AIDs; however, no systematic study has been conducted on the occurrence of AIDs in the families of MS patients. Using a standardized interview focused on AID...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1600-0404.2000.101001036.x
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVE:Machado-Joseph disease (MJD)/spinocerebellar ataxia type 3 is an autosomal dominant spinocerebellar degeneration, for which there is no effective treatment. PATIENTS AND METHODS:This study involved the clinical response of lamotrigine (LTG) on six MJD patients with early truncal ataxia and the effect of LTG ...
journal_title：Acta neurologica Scandinavica
pub_type： 临床试验,杂志文章
doi：10.1111/j.1600-0404.2005.00405.x
更新日期：2005-06-01 00:00:00
abstract：:A retrospective study of variations of therapeutic response (dyskinesia and on-off phenomenon) in Parkinson's disease was conducted on 278 patients treated with levodopa for at least 6 months and hospitalized at National Neurological Institute "C. Besta" of Milan between 1974 and 1984. Variations of therapeutic respon...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.1990.tb00983.x
更新日期：1990-05-01 00:00:00
abstract：:The effect of a new peripherally acting muscle relaxant drug Dantrium, on spasticity tested on 11 hemiplegic patients. The effect was evaluated both with regular clinical examination and with electromyographic technique. The latter concerned a quantitative analysis of the patients' voluntary control of fine neuromuscu...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：1975-05-01 00:00:00
abstract：OBJECTIVES:To estimate dementia prevalence in Spain. MATERIALS AND METHODS:Nine probabilistic and geographically defined samples participated. A screening design based on the MMSE was implemented. Positively screened individuals underwent clinical evaluation. The total number of cases in Spain was estimated. Prevalenc...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.2010.01398.x
更新日期：2011-05-01 00:00:00
abstract：:A group of asymptomatic HIV-infected patients (CDC II and III) was followed-up over a two year period with semi-annual neuropsychological testing. Of the total sample of 36 subjects, all were retested at test two (T2), 19 at test three (T3) and 13 at test four (T4). A subgroup of subjects was further tested on a simpl...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.1993.tb04082.x
更新日期：1993-02-01 00:00:00
abstract：OBJECTIVES:Cerebrospinal fluid (CSF) from some patients with amyotrophic lateral sclerosis (ALS) has been demonstrated to significantly reduce the neuronal viability of primary cell cultures of motor neurons. We aimed to study the potential clinical consequences associated with the cytotoxicity of CSF in a cohort of pa...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/ane.12717
更新日期：2017-09-01 00:00:00
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journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/ane.12672
更新日期：2017-03-01 00:00:00
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journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章,评审
doi：
更新日期：2001-04-01 00:00:00
abstract：:We investigated the EEG frequency distribution by quantitative EEG (QEEG) in 28 children with type 1 diabetes and 28 age- and sex-matched control children. Among the diabetic children, 15 had experienced episodes of severe hypoglycemia (SH group) and 13 had not experienced such episodes (non-SH group). The EEG analysi...
journal_title：Acta neurologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1996-06-01 00:00:00
abstract：:Multiple system atrophy (MSA) is a heterogeneous group of central neurological degenerations often associated with diffuse deterioration of the hypothalamic cholinergic neurons. In the hypothesis of an altered cholinergic regulation of vasopressin release, we evaluated vasopressin response to metoclopramide (20 mg i.v...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.1992.tb04047.x
更新日期：1992-04-01 00:00:00
abstract：:The results of follow-up of 76 children with progressive ataxia first reported in 1988 are described with special reference to type of potential underlying metabolic diseases. In 70% of cases the clinical follow-up did not lead to reconsideration of diagnoses. Six of 23 biochemically and morphologically re-examined ch...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.1994.tb01684.x
更新日期：1994-04-01 00:00:00
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journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1600-0404.2002.01329.x
更新日期：2002-09-01 00:00:00
abstract：:There has been accumulation of the nutritional muscular dystrophy of the cattle in a certain western district of Finland where the prevalence of multiple sclerosis (MS) is also highest. This animal disease is due to lack of selenium (Se) and vitamin E. The Se content of whole blood was low (52.6 +/- 11.3 ng/ml) in MS ...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.1976.tb04806.x
更新日期：1976-09-01 00:00:00
abstract：:We describe eight patients from three families presenting with myoclonus, ataxia, infrequent seizures and minimal intellectual impairment. All were Arabs from different parts of the Arabian peninsula. The new consensus on terminology, genetic and clinical definition of Baltic myoclonus, Ramsay Hunt syndrome and Unverr...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.1992.tb05126.x
更新日期：1992-11-01 00:00:00
abstract：:The aim of this study was to ascertain whether there is an association between risk of multiple sclerosis (MS) and birth order position. Our reference population was 198,000 persons born in the period 1930-50 and recorded in the register of school health records from the school health service of the Copenhagen council...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.1980.tb01509.x
更新日期：1980-06-01 00:00:00
abstract：OBJECTIVE:Ultrasonographic assessment of carotid artery plaque morphology is widely used to identify patients at high risk for stroke. However, the reliability of plaque analysis in high-grade stenosis is uncertain. We determined the interrater reliability of sonographic plaque morphology analysis in patients with seve...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.1999.tb00659.x
更新日期：1999-01-01 00:00:00
abstract：OBJECTIVES:Epilepsia partialis continua (Kojewnikow's syndrome) can be classified into 2 groups. The 1st group had stable neurological deficit, and the 2nd group had slowly progressive neurological deficit. The latter usually manifests not tetraplegia, but hemiplegia. We describe 3 patients with epilepsia partialis con...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0404.1997.tb00296.x
更新日期：1997-12-01 00:00:00
abstract：OBJECTIVES:To explore adherence, persistence, and treatment patterns in patients with multiple sclerosis (MS) in Finland treated with disease-modifying therapies (DMTs) for active MS in 2005-2018. MATERIALS AND METHODS:The study cohort was identified using the Drug Prescription Register of Social Insurance Institute, ...
journal_title：Acta neurologica Scandinavica
pub_type： 杂志文章
doi：10.1111/ane.13301
更新日期：2020-12-01 00:00:00
