Risk of multiple sclerosis inversely associated with birth order position.

Abstract:

:The aim of this study was to ascertain whether there is an association between risk of multiple sclerosis (MS) and birth order position. Our reference population was 198,000 persons born in the period 1930-50 and recorded in the register of school health records from the school health service of the Copenhagen council. We compared 46 persons from the register who had developed MS with matched controls from the register, three for each case. An inverse association between risk of MS and birth order position was found. Early birth orders tend to delay exposure to an infectous agent from early childhood to a later age. Therefore, our finding supports the hypothesis that MS is causally related to an infection that is inapparent when it occurs in early childhood, while infection later in life may result in severe disease

journal_name

Acta Neurol Scand

authors

Isager H,Andersen E,Hyllested K

doi

10.1111/j.1600-0404.1980.tb01509.x

subject

Has Abstract

pub_date

1980-06-01 00:00:00

pages

393-6

issue

6

eissn

0001-6314

issn

1600-0404

journal_volume

61

pub_type

杂志文章
  • Cerebral abscess. A long-term follow-up.

    abstract::During the period 1935-1976, 200 cases of brain abscess were treated in the University Clinic of Neurosurgery, Rigshospitalet, Copenhagen. 119 patients survived. Out of 40 deaths during the follow-up period, 37 were unrelated to the previous brain abscess. 12 patients emigrated and were lost to follow-up. History and ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1983.tb03150.x

    authors: Nielsen H,Harmsen A,Gyldensted C

    更新日期:1983-06-01 00:00:00

  • Enteric-coated acetylsalicylic acid plus dipyridamole compared with anticoagulants in the prevention of ischemic events in patients with transient ischemic attacks.

    abstract::From December 1976 through March 1982, 188 patients entered an open non-random study carried out on hospitalized patients with a history of transient ischemic attacks or amaurosis fugax. Ninety-two patients received peroral anticoagulants usually combined with heparin treatment during the first days of treatment, and ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1985.tb03232.x

    authors: Eriksson SE

    更新日期:1985-06-01 00:00:00

  • Voxel-based morphometry study on monozygotic twins discordant for Alzheimer's disease.

    abstract:OBJECTIVES:We set to investigate the possible role of genes and environment in developing Alzheimer's disease (AD) in monozygotic twin pairs discordant for AD. METHODS:Three pairs of twins discordant for AD, who were enrolled in the Finnish Twin Cohort, were used in the study and compared with 13 controls. Gray matter...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12480

    authors: Rossi R,Pievani M,Järvenpää T,Testa C,Koskenvuo M,Räihä I,Kaprio J,Frisoni GB,Rinne JO,Laakso MP

    更新日期:2016-06-01 00:00:00

  • Emotional responses during unilateral amobarbital anesthesia: differential hemispheric contributions?

    abstract:OBJECTIVES:To explore (1) effects of test and subject variables in determining euphoric and dysphoric responses during unilateral amobarbital anesthesia and (2) which cerebral areas contribute to the emotional responses. METHOD:Incidence of euphoric and dysphoric reactions during left- and right-sided amobarbital anes...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2004.00329.x

    authors: Stabell KE,Andresen S,Bakke SJ,Bjørnaes H,Borchgrevink HM,Heminghyt E,Røste GK

    更新日期:2004-11-01 00:00:00

  • EMG before and after cervical anterior discectomy.

    abstract:INTRODUCTION:In patients with cervical root syndromes, the relation between clinical findings and EMG results, the value of the registration of the H-reflex latency of the flexor carpi radial muscle (HFCR) and the rate of recovery of EMG abnormalities following surgery are unclear. METHODS:In 68 patients with cervical...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1600-0404.1995.tb00138.x

    authors: van den Bent MJ,Oosting J,Laman DM,van Duijn H

    更新日期:1995-10-01 00:00:00

  • Soluble class 1 antigens (sHLA) in CSF and serum of patients with HIV infection.

    abstract::sHLA are secreted by B and T lymphocytes upon activation. These antigens are present in serum and cerebrospinal fluid (CSF). The establishment of a sHLA index, IH = (CSF sHLA/serum sHLA)/(CSF albumin/serum albumin) helped us to define that values above 9.7 reflect an intrathecal synthesis of these proteins. IH was sig...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1990.tb01580.x

    authors: Alvarez-Cermeño JC,Casado C,Villar LM,Ferreira A,Varela JM,Dominguez M,Bootello A,Najera R,Gonzalez-Porque P

    更新日期:1990-07-01 00:00:00

  • Nerve conduction velocity and circulating immunocomplexes in type 1 diabetic children.

    abstract::There is evidence from several laboratories of an increased prevalence of circulating immuno-complexes (CIC) in diabetic patients. It has also been suggested that CIC are pathogenetically related to chronic diabetic complications. The aim of this study was to assess peripheral nerve function in children with Type 1 di...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1991.tb04672.x

    authors: Fierro B,Modica A,Cardella F,Raimondo D,Triolo G,Meli F

    更新日期:1991-03-01 00:00:00

  • Large striatocapsular infarcts: clinical presentation and pathogenesis in comparison with lacunar and cortical infarcts.

    abstract::In a well-defined prospective series of 247 patients with a first-ever supratentorial brain infarct, 15 patients (6%; 95% confidence interval 3-9%) had a large striatocapsular infarct. Twelve (80%) had signs of cortical dysfunction, whereas risk factor profile, frequency of significant carotid stenosis, and frequency ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1992.tb05089.x

    authors: Boiten J,Lodder J

    更新日期:1992-09-01 00:00:00

  • Mood and neural correlates of excessive daytime sleepiness in Parkinson's disease.

    abstract::For patients with Parkinson's disease (PD), excessive daytime sleepiness (PD-EDS) is a debilitating non-motor symptom and may be affected by mood symptoms, especially depression and anxiety. Few neuroimaging works have attempted to identify the neural features of PD-EDS, but various findings were reported. The purpose...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/ane.12704

    authors: Wen MC,Chan LL,Tan LCS,Tan EK

    更新日期:2017-08-01 00:00:00

  • Transcranial Doppler recordings in raised intracranial pressure.

    abstract::The pulsatility index (PI) registered by the transcranial doppler (TCD) was examined in relation to arterial pCO2 (paCO2) and epidural pressure (ICP). In 10 normal subjects PI was studied during variations in paCO2. In 10 neurosurgical patients with head injuries concomitant measurements of PI and ICP were obtained. T...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1993.tb04142.x

    authors: Homburg AM,Jakobsen M,Enevoldsen E

    更新日期:1993-06-01 00:00:00

  • Visually evoked potentials in respiratory chain disorders.

    abstract:OBJECTIVES:Little is known about the frequency of abnormal visually evoked potentials (VEPs) in patients with respiratory chain disorders (RCDs). We thus wanted to investigate the frequency of abnormal VEPs in RCDs, how often VEPs are abnormal despite normal visual acuity, and which of the VEP variables are most often ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2001.00167.x

    authors: Finsterer J

    更新日期:2001-07-01 00:00:00

  • CT and MRI in late-onset metachromatic leukodystrophy.

    abstract::A 23-year-old patient suffering from mental deterioration was referred for CT study following her first epileptic fit. The study disclosed generalized atrophy and diffuse symmetric white matter hypodensities. Similar findings were found in her 13-year-old retarded sister. The diagnosis of metachromatic leukodystrophy ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1987.tb07891.x

    authors: Reider-Grosswasser I,Bornstein N

    更新日期:1987-01-01 00:00:00

  • Pharmacological studies of the uninhibited neurogenic bladder. I. The influence of repeated filling and various filling rates on the cystometrogram of neurological patients with normal and uninhibited neurogenic bladder.

    abstract::The influence on the cystometrogram of repeated filling and varying filling rates was studied in two groups of neurological patients, one with normal and one with uninhibited neurogenic bladder. A technique which permits an even bladder filling and a continuous recording of the intravesical pressure was used. The effe...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Jensen D Jr

    更新日期:1981-09-01 00:00:00

  • Antiepileptic drugs, foetal malformations and spontaneous abortions.

    abstract:BACKGROUND:Some recent studies have found an association between foetal malformations in earlier antiepileptic drug (AED)-exposed pregnancies and an increased hazard of such malformations in subsequent pregnancies. We investigated this matter further, and also considered the possible role of spontaneous abortions in pr...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/ane.12672

    authors: Vajda FJ,O'Brien TJ,Graham JE,Hitchcock AA,Lander CM,Eadie MJ

    更新日期:2017-03-01 00:00:00

  • Analysis of peripheral blood lymphocyte phenotype and function during dexamethazone treatment of progressive multiple sclerosis.

    abstract::Five patients with chronic progressive multiple sclerosis (MS) and three control patients with lumbar disc herniation were treated with dexamethazone during 14 days. The effect on peripheral blood T-cell subsets and on the proliferative response of peripheral blood mononuclear cells (PBMC) to pokeweed mitogen (PWM) an...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1991.tb04914.x

    authors: Salmaggi A,Baldetorp B,Milanese C,Nespolo A,Parma R,Sandberg-Wollheim M

    更新日期:1991-08-01 00:00:00

  • A follow-up study of neuropsychological function in asymptomatic HIV-infected patients.

    abstract::A group of asymptomatic HIV-infected patients (CDC II and III) was followed-up over a two year period with semi-annual neuropsychological testing. Of the total sample of 36 subjects, all were retested at test two (T2), 19 at test three (T3) and 13 at test four (T4). A subgroup of subjects was further tested on a simpl...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1993.tb04082.x

    authors: Karlsen NR,Reinvang I,Frøland SS

    更新日期:1993-02-01 00:00:00

  • Rufinamide in children and adults in routine clinical practice.

    abstract:OBJECTIVE:To explore the long-term effectiveness of rufinamide in managing Lennox-Gastaut Syndrome (LGS), other epileptic encephalopathies, and intractable focal epilepsies in adults and children in routine clinical practice. METHODS:A multicentre, retrospective chart review of patients prescribed adjunctive rufinamid...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章,多中心研究

    doi:10.1111/ane.12572

    authors: Jaraba S,Santamarina E,Miró J,Toledo M,Molins A,Burcet J,Becerra JL,Raspall M,Pico G,Miravet E,Cano A,Fossas P,Fernández S,Falip M

    更新日期:2017-01-01 00:00:00

  • Stroke in children under 16 years of age. Clinical and etiological difference with adults.

    abstract:OBJECTIVES:The aim of this study was to re-evaluate the clinical features of stroke in children, their outcome and the place of the different mechanisms, in the light of CT-scan and magnetic resonance imaging. METHODS:A 10-year review of the Dijon Childhood Neurology Clinic experience (1985-1995) identified 54 patient...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1997.tb00306.x

    authors: Giroud M,Lemesle M,Madinier G,Manceau E,Osseby GV,Dumas R

    更新日期:1997-12-01 00:00:00

  • Thermal threshold determination in alcoholic polyneuropathy: an improvement of diagnosis.

    abstract::Reports on the incidence of alcoholic polyneuropathies are variable depending on diagnostic tools. In this study, 50 chronic alcoholics with positive MALT (Munich Alcoholism Test) and greater than seven years history of excessive alcohol abuse were examined neurologically. Tibial and peroneal motor and sural nerve con...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1995.tb07026.x

    authors: Hilz MJ,Zimmermann P,Claus D,Neundörfer B

    更新日期:1995-05-01 00:00:00

  • Examination of the SLITRK1 gene in Caucasian patients with Tourette syndrome.

    abstract:OBJECTIVE:To determine whether variants in the Slit and Trk-like 1 gene (SLITRK1) are present in American Caucasian population of patients with Tourette syndrome (TS). METHODS:We sequenced the 3'-untranslated region for var321 and the whole coding region in the SLITRK1 gene in 82 Caucasian patients with TS from North ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2006.00706.x

    authors: Deng H,Le WD,Xie WJ,Jankovic J

    更新日期:2006-12-01 00:00:00

  • Clinical and epidemiological features of motor neuron disease in south-western Greece.

    abstract:OBJECTIVE:To evaluate the epidemiological and clinical features of motor neuron disease (MND) in a region (835,000 inhabitants) of south-western Greece. PATIENTS AND METHODS:The medical records of all patients diagnosed with adult-onset MND at the Department of Neurology of the University Hospital of Patras from 1990 ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.2004.00362.x

    authors: Argyriou AA,Polychronopoulos P,Papapetropoulos S,Ellul J,Andriopoulos I,Katsoulas G,Salakou S,Chroni E

    更新日期:2005-02-01 00:00:00

  • Unchanged striatal dopamine transporter availability in narcolepsy: a PET study with [11C]-CFT.

    abstract:OBJECTIVE:To investigate dopamine reuptake sites (dopamine transporter) in the caudate nucleus and putamen in narcolepsy. PATIENTS AND METHODS:Ten patients with narcolepsy and 15 controls were studied with positron emission tomography. A cocaine analogue [11C]-CFT was used as a radioligand. RESULTS:The uptake of[11C]...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0404.2003.00175.x

    authors: Rinne JO,Hublin C,Någren K,Helenius H,Partinen M

    更新日期:2004-01-01 00:00:00

  • Effect of baclofen on gait in spastic MS patients.

    abstract:OBJECTIVES:To measure gait and postural stability by objective methods in spastic MS patients and to evaluate the effect of baclofen on gait and postural stability. PATIENTS AND METHODS:Fourteen spastic MS patients were examined in a placebo controlled double-blind, cross-over trial of oral baclofen treatment. The gai...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1034/j.1600-0404.2000.101004244x./

    authors: Orsnes GB,Sørensen PS,Larsen TK,Ravnborg M

    更新日期:2000-04-01 00:00:00

  • Diffuse cerebral sclerosis, melanoderma and adrenal insufficiency (adreno-leukodystrophy).

    abstract::Two cases of adrenoleukodystrophy are described. The pathological picture was consistent with earlier observations about the disease with the difference that the brain tissue revealed material which stained metachromatically with toluidine blue and was insoluble in fat solvents. ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1978.tb02870.x

    authors: Hormia M

    更新日期:1978-08-01 00:00:00

  • Optic atrophy in experimental vitamin B12 deficiency in monkeys.

    abstract::The clinical findings and pathological changes of the visual pathway of vitamin B12 deficient monkeys have been described. The cellular morphology and counts of the peripheral blood and bone marrow remained normal during the study (nine deficient, three controls: one still alive in each group). Visual impairment was n...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1980.tb02991.x

    authors: Chester EM,Agamanolis DP,Harris JW,Victor M,Hines JD,Kark JA

    更新日期:1980-01-01 00:00:00

  • Urinary excretion of taurine in epilepsy.

    abstract::The level of urinary taurine and 17-hydroxycorticosteroids were estimated in 19 cases of epilepsy. These levels were then compared with those of normal healthy subjects. The urinary taurine levels were significantly higher in epilepsy and have diagnostic as well as prognostic significance. ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1983.tb04853.x

    authors: Rao A,Baliga L,Raja A,Rao SN

    更新日期:1983-12-01 00:00:00

  • Effect of sympathetic denervation on chronic cold injuries in rabbit brain. A microangiographical and histological study.

    abstract::Sympathetic denervation of the brain vessels was performed uni- or bilaterally in 13 adult rabbits, and cortical cold lesions were induced bilaterally 10-18 days afterwards. After a further 4-35 days the vascular and morphological changes in the lesion areas were studied histologically and with angiography. No differe...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1976.tb04801.x

    authors: West KA,Hassler O

    更新日期:1976-09-01 00:00:00

  • Juvenile neurolipidosis of Bernheimer-Seitelberger's type. Histopathological and biochemical findings.

    abstract::Two children are reported, who became diseased at the age of 4 and 2 years, respectively, with progressive upper motor neuron symptoms leading to severe disability within a few years. The boy died at age 10 and autopsy disclosed a severe gangliolipidosis throughout the central nervous system, maximal in the brain stem...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1977.tb01464.x

    authors: Brandt S,Clausen J,Diemer NH,Faurholt-Pedersen V,Jensen GE,Lademann A,Melchior JC

    更新日期:1977-12-01 00:00:00

  • Clinical and neurophysiological abnormalities before and after reconstruction of the anterior cruciate ligament of the knee.

    abstract:OBJECTIVES:We aimed to study knee proprioception and somatosensory evoked potentials (SEPs) to stimulation of the common peroneal nerve (CPN) in 7 patients with lesion of the anterior cruciate ligament (ACL) before and after ACL reconstruction. MATERIALS AND METHODS:We recorded the spinal N14 and scalp P27 potentials ...

    journal_title:Acta neurologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1999.tb00680.x

    authors: Valeriani M,Restuccia D,Di Lazzaro V,Franceschi F,Fabbriciani C,Tonali P

    更新日期:1999-05-01 00:00:00

  • Treatment of Huntington's chorea with bromocriptine.

    abstract::The authors tested the effects of 2-Br-ergocriptine (bromocriptine, CB-154), a drug which exerts a mixed agonist-antagonist activity on the dopaminergic receptors, in 12 patients with Huntington Chorea in a double-blind crossover trial. This treatment significantly reduced the abnormal involuntary movements and the di...

    journal_title:Acta neurologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0404.1977.tb01407.x

    authors: Frattola L,Albiazzati MG,Spano PF,Trabucchi M

    更新日期:1977-07-01 00:00:00