Optic atrophy in experimental vitamin B12 deficiency in monkeys.

abstract：:Vigabatrin (VGB), an irreversible inhibitor of gamma-aminobutyric acid (GABA) transaminase, is approved as adjunct treatment of refractory partial seizures as well as infantile spasms. Although VGB has been proven to be effective, its use is limited by the risk of retinopathy and associated peripheral visual field def...

journal_title：Acta neurologica Scandinavica

authors： Heim MK,Gidal BE

更新日期：2012-10-01 00:00:00

abstract：:In 5 patients with definite or highly probable MS, unusually large hypodense plaques are seen by computerized tomography (CT scan). The active plaques all show enhancement after i.v. contrast medium injection, suggestive of blood-brain-barrier-damage, and differ from the well-known CT findings in chronic MS patients, ...

journal_title：Acta neurologica Scandinavica

authors： Lidegaard O,Gyldensted C,Juhler M,Zeeberg I

更新日期：1983-08-01 00:00:00

abstract：OBJECTIVES:Fatigue is a disabling and dopa-resistant symptom in Parkinson's disease (PD). Pathological studies have shown that both peripheral and central cholinergic systems are involved in PD. Electrophysiological investigation showed decremental muscle responses following repetitive nerve stimulation (RNS). We hypot...

journal_title：Acta neurologica Scandinavica

authors： Hwang WJ,Lin TS

更新日期：2001-11-01 00:00:00

abstract：:Once believed to be extremely uncommon, due to magnetic resonance imaging cavernous hemangiomas of the spinal cord are detected with increasing frequency. Management of both symptomatic and asymptomatic intramedullary cavernous hamangiomas is therefore of growing importance. However, experience with treatment and foll...

journal_title：Acta neurologica Scandinavica

authors： Kondziella D,Brodersen P,Laursen H,Hansen K

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to analyse the presence of the granulocyte-macrophage colony-stimulating factor (GM-CSF) in human cerebrospinal fluid (SF) of patients affected by multiple sclerosis (MS) in comparison with non-inflammatory neurological diseases. MATERIAL AND METHODS:All SFs were collected from...

journal_title：Acta neurologica Scandinavica

authors： Leonardi A,Penco S,Gramigni C,Bason C,Ribizzi G,Gazzola P,Mancardi GL,Bianchi-Scarrà G,Abbruzzese M,Garrè C

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:Association of leuko-araiosis (LA) with certain risk factors has been reported in Western patients. This is a case-control study to determine the risk factors and the type of stroke associated with LA in Saudi patients. DESIGN AND SETTING:398 consecutive Saudi patients with the diagnosis of stroke admitted o...

journal_title：Acta neurologica Scandinavica

authors： Awada A,Omojola MF

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Treatment with lamotrigine (LTG) during pregnancy is associated with a pronounced risk of seizure deterioration, because pregnancy accelerates LTG elimination. The extent to which pregnancy affects LTG pharmacokinetics is unpredictable and varies considerably among patients. AIM:We propose an algorithm for ...

journal_title：Acta neurologica Scandinavica

authors： Sabers A

更新日期：2012-07-01 00:00:00

abstract：:This study concerns the distribution of T-cell subsets as determined by specific monoclonal antibodies in 50 individuals with complex partial seizures (31) and primary generalized tonic-clonic seizures (19), and in 30 healthy controls. The epileptic group had significantly fewer circulating T4 "helper" lymphocytes and...

journal_title：Acta neurologica Scandinavica

authors： Eeg-Olofsson O,Prchal JF,Andermann F

更新日期：1985-08-01 00:00:00

abstract：:Computed tomographic features of 7 cases of the late infantile form of MLD confirmed by sural nerve biopsy are presented. Diffuse symmetrical white matter, low attenuation of the cerebral parenchyma was the common feature. Hypodensity of the temporal lobes and the cerebellar hemispheres are 2 features which have not b...

journal_title：Acta neurologica Scandinavica

authors： Jayakumar PN,Aroor SR,Jha RK,Arya BY

更新日期：1989-01-01 00:00:00

abstract：:The objective of this paper is to evaluate the accuracy of conventional diagnostic criteria for Parkinson's disease and give an overview of alternative causes to parkinsonian syndromes. We also propose a new approach to the clinical diagnosis of Parkinson's disease, which may improve the diagnostic accuracy. The avail...

journal_title：Acta neurologica Scandinavica

authors： Larsen JP,Dupont E,Tandberg E

更新日期：1994-04-01 00:00:00

abstract：:The authors tested the effects of 2-Br-ergocriptine (bromocriptine, CB-154), a drug which exerts a mixed agonist-antagonist activity on the dopaminergic receptors, in 12 patients with Huntington Chorea in a double-blind crossover trial. This treatment significantly reduced the abnormal involuntary movements and the di...

journal_title：Acta neurologica Scandinavica

authors： Frattola L,Albiazzati MG,Spano PF,Trabucchi M

更新日期：1977-07-01 00:00:00

abstract：OBJECTIVES:To estimate dementia prevalence in Spain. MATERIALS AND METHODS:Nine probabilistic and geographically defined samples participated. A screening design based on the MMSE was implemented. Positively screened individuals underwent clinical evaluation. The total number of cases in Spain was estimated. Prevalenc...

journal_title：Acta neurologica Scandinavica

authors： Virués-Ortega J,de Pedro-Cuesta J,Vega S,Seijo-Martínez M,Saz P,Rodríguez F,Rodríguez-Laso A,Reñé R,de Las Heras SP,Mateos R,Martínez-Martín P,Mahillo-Fernández I,López-Pousa S,Lobo A,Reglà JL,Gascón J,García FJ,Fernánd

更新日期：2011-05-01 00:00:00

abstract：:Amino acid concentrations in plasma of patients with Huntington's disease (HD) were determined in 16 patients and 21 age- and sex-matched healthy controls. Alanine and isoleucine were significantly decreased in HD plasma whereas arginine, histidine, leucine, lysine, ornithine, proline, serine, threonine, tyrosine, and...

journal_title：Acta neurologica Scandinavica

authors： Reilmann R,Rolf LH,Lange HW

更新日期：1995-03-01 00:00:00

abstract：:Patients with multiple sclerosis have an increased risk of infections compared to the general population. The increased risk has been described for decades and is not alone attributed to the use of disease-modifying drugs, but secondary to the disability. The introduction of more potent immunomodulatory drugs may caus...

journal_title：Acta neurologica Scandinavica

authors： Celius EG

更新日期：2017-11-01 00:00:00

abstract：:Cerebral angiography was carried out in two diabetic patients in the evaluation of minor vascular ischemic episodes. A transient acute renal failure following cerebral angiography was accompanied by a transient comatose episode with severe unilateral neurological deficits. A functional depression of the injected hemis...

journal_title：Acta neurologica Scandinavica

authors： Skyhøj Olsen T,Lund P,Praestholm J

更新日期：1981-12-01 00:00:00

abstract：OBJECTIVE:To study the relationship between cerebral hemodynamics and clinical performance in normal pressure hydrocephalus (NPH), before and after surgery. MATERIAL AND METHODS:Ten patients were studied prospectively before and 3 months after shunt surgery by means of transcranial Doppler (TCD). Clinical performance ...

journal_title：Acta neurologica Scandinavica

authors： Bakker SL,Boon AJ,Wijnhoud AD,Dippel DW,Delwel EJ,Koudstaal PJ

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVES:We studied the in vitro production of variably MS-related cytokines from Sardinian MS and healthy donors bearing the two "Sardinian" MS-associated HLA-DR alleles: DR3 and DR4, with the purpose to evidentiate possible differences in their immune response. MATERIALS AND METHODS:ELISA were used for detection o...

journal_title：Acta neurologica Scandinavica

authors： Sotgiu S,Serra C,Marrosu MG,Dolei A,Pugliatti M,Murgia B,Aiello I,Rosati G

更新日期：1998-11-01 00:00:00

abstract：:Out of a data pool of 1271 patients with Multiple Sclerosis (MS) a total of 109 cases are selected having a sole spinal symptomatology throughout the course of the disease. This group differs in three particular features from the non-spinal forms of MS: In this group there is a higher percentage of females, the age at...

journal_title：Acta neurologica Scandinavica

authors： Poser S,Herrmann-Gremmels I,Wikström J,Poser W

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:Early administration of paracetamol may improve outcome of patients with acute stroke and a baseline body temperature of 37°C or above by lowering body temperature and preventing fever. Besides its antipyretic effects, paracetamol may affect blood pressure through cyclooxygenase-2 inhibition. We therefore ai...

journal_title：Acta neurologica Scandinavica

authors： den Hertog HM,van der Worp HB,van Gemert HM,van Gijn J,Koudstaal PJ,Dippel DW

更新日期：2012-04-01 00:00:00

abstract：:Sixteen patients with HTLV-1 associated myelopathy (HAM) were examined for the presence of HTLV-1 provirus genome by Southern blot analysis of genomic DNA from peripheral blood mononuclear (PBM) cells. Random integration of the provirus was detected in 14 of 16 HAM patients. By contrast, the provirus genome could not ...

journal_title：Acta neurologica Scandinavica

authors： Nishimura M,Adachi A,Akiguchi I,Shirahata N,Maeda M,Ishimoto A,Mezaki T,Kimura J

更新日期：1990-03-01 00:00:00

abstract：:The effect of a new peripherally acting muscle relaxant drug Dantrium, on spasticity tested on 11 hemiplegic patients. The effect was evaluated both with regular clinical examination and with electromyographic technique. The latter concerned a quantitative analysis of the patients' voluntary control of fine neuromuscu...

journal_title：Acta neurologica Scandinavica

authors： Jonsson B,Ladd H,Afzelius-Frisk I,Lindberg-Broman AM

更新日期：1975-05-01 00:00:00

abstract：OBJECTIVE:Blepharoclonus (BLC) denotes a large amplitude, involuntary tremors of the orbicularis oculi muscles, observed during gentle closure of the eyelids. BLC may follow major head trauma. Four patients with Arnold-Chiari malformation (ACM) and BLC are described. MATERIALS AND METHODS:The first patient had facial ...

journal_title：Acta neurologica Scandinavica

authors： Jacome DE

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Thirty patients with glioblastoma multiforme (GBM) were treated by boron neutron capture therapy (BNCT) at the Studsvik facility in Sweden, in a clinical trial exploring a procedure in which 900 mg p-boronophenylalanine (BPA) per kilo body weight was infused in 6 h. OBJECTIVE:The present study was designed ...

journal_title：Acta neurologica Scandinavica

authors： H-Stenstam B,Pellettieri L,Sköld K,Rezaei A,Brun A

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Hereditary haemorrhagic telangiectasia (HHT) is a dominantly inherited disease characterized by a wide variety of clinical manifestations, including pulmonary arteriovenous malformations (PAVMs), which due to paradoxical embolization may cause cerebral abscess. OBJECTIVE:To estimate the risk of cerebral abs...

journal_title：Acta neurologica Scandinavica

authors： Kjeldsen AD,Tørring PM,Nissen H,Andersen PE

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVES:As part of a door-to-door survey of neurologic diseases, we investigated the prevalence of lumbosacral radiculopathy (LR) in two Sicilian municipalities (N = 14,540, as of November 1, 1987). MATERIAL & METHODS:During phase 1, we administered a brief screening instrument to subjects in the study population. ...

journal_title：Acta neurologica Scandinavica

authors： Savettieri G,Salemi G,Rocca WA,Meneghini F,D'Arpa A,Morgante L,Coraci MA,Reggio A,Grigoletto F,Di Perri R

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to examine the association between the frequency of alcohol consumption and stroke mortality among eastern Finnish men. MATERIAL AND METHODS:This study is a population-based sample of men with an average follow-up of 20.2 years. A total of 2609 men with no history of stroke at ...

journal_title：Acta neurologica Scandinavica

authors： Rantakömi SH,Kurl S,Sivenius J,Kauhanen J,Laukkanen JA

更新日期：2014-08-01 00:00:00

abstract：:For patients with Parkinson's disease (PD), excessive daytime sleepiness (PD-EDS) is a debilitating non-motor symptom and may be affected by mood symptoms, especially depression and anxiety. Few neuroimaging works have attempted to identify the neural features of PD-EDS, but various findings were reported. The purpose...

journal_title：Acta neurologica Scandinavica

authors： Wen MC,Chan LL,Tan LCS,Tan EK

更新日期：2017-08-01 00:00:00

abstract：:Adenylate kinase (AK) was determined in a lumbo-cisternal cerebrospinal fluid (CSF) gradient and in CSF from patients with mental deterioration. AK activity was unchanged in the gradient and different from albumin and albumin ratio (alb CSF/albumin serum), a blood-brain barrier marker in the same gradient. No differen...

journal_title：Acta neurologica Scandinavica

authors： Ahlberg J,Blomstrand C,Ronquist G,Wikkelsö C

更新日期：1985-11-01 00:00:00

abstract：:The production of oxygen-free radicals and their subsequent peroxidative action on membrane unsaturated fatty acids could be enhanced after subarachnoid hemorrhage. High-dose methylprednisolone (30 mg/Kg i.v.) treatment can antagonize acute SAH-induced brain hypoperfusion and protect the ultrastructural integrity of e...

journal_title：Acta neurologica Scandinavica

authors： Marzatico F,Gaetani P,Buratti E,Messina AL,Ferlenga P,Rodriguez y Baena R

更新日期：1990-10-01 00:00:00

abstract：:Authors addressed the question whether the byosynthesis and the release of specific eicosanoids may occur in human brain cortex, and if the qualitative pattern of arachidonic acid metabolism is similar to that observed in experimental SAH. Human brain samples from 18 patients operated on for anterior communicating art...

journal_title：Acta neurologica Scandinavica

authors： Gaetani P,Marzatico F,Rodriguez y Baena R

更新日期：1992-08-01 00:00:00