Cerebrospinal fluid cytotoxicity does not affect survival in amyotrophic lateral sclerosis.

abstract：:Stroke although rare in children, is an important cause of morbidity in the paediatric age group. Over a period of 8 years, 43 children (17 boys and 26 girls) in the age groups of 1-16 years (mean 8.02 yrs) presented with stroke which constituted 10% of all strokes in the young and 0.7% of all paediatric admissions. T...

journal_title：Acta neurologica Scandinavica

authors： Nagaraja D,Verma A,Taly AB,Kumar MV,Jayakumar PN

更新日期：1994-10-01 00:00:00

abstract：:Peripheral blood lymphocytes from 23 out of 27 (85%) patients with multiple sclerosis responded to MS brain homogenates by increased formation of active E-rosettes. Lymphocytes from only six out of 78 (8%) patients with other neurological diseases responded to MS brain homogenates. The possible value of the test in th...

journal_title：Acta neurologica Scandinavica

authors： Offner H,Fog T,Rastogi SC,Konat G,Clausen J

更新日期：1979-03-01 00:00:00

abstract：:In order to characterize the CSF (cerebrospinal fluid) lymphocytes in CNS (central nervous system) inflammation, we examined paired samples of CSF and PB (peripheral blood) of 19 patients with acute aseptic meningitis, performing the dual labelling method on flow cytometry. Significantly higher percentages of CD3+ (T ...

journal_title：Acta neurologica Scandinavica

authors： Uchihara T,Ikeda M,Takahashi H,Yoshida S,Tsukagoshi H

更新日期：1990-05-01 00:00:00

abstract：OBJECTIVES:Dopamine neurotransmission is a critical factor for executive function, which is controlled by the prefrontal cortex in humans. Although the contribution of genetic factors to the regulation of brain dopaminergic activity is widely acknowledged, identification of a genotype-phenotype association has not yet ...

journal_title：Acta neurologica Scandinavica

authors： Mitaki S,Isomura M,Maniwa K,Yamasaki M,Nagai A,Nabika T,Yamaguchi S

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To compare the sensitivity and specificity of isoelectric focusing (IEF) with immunofixation, agarose gel electrophoresis (AGE) and the IgG index in detecting intrathecally synthesized IgG in multiple sclerosis (MS) and in other nervous system disorders. MATERIALS AND METHODS:Cerebrospinal fluid (CSF) and se...

journal_title：Acta neurologica Scandinavica

authors： Lunding J,Midgard R,Vedeler CA

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Valproic acid (VPA) may induce hyperammonemic encephalopathy. On the other hand, seizure-inducing effects of antiepileptic drugs (AEDs) may be a paradoxical reaction or a result of AED-induced encephalopathy (commonly induced by VPA). METHODS:We present the case of a 19-year-old male who developed acute men...

journal_title：Acta neurologica Scandinavica

authors： Velioğlu SK,Gazioğlu S

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and tolerability of the treatment with valproic acid (VPA) in patients with status epilepticus (SE) or acute repetitive seizures (ARS) comparing it with phenytoin (PHT) treatment. MATERIALS AND METHODS:Patients with SE or ARS were treated in a consecutive manner with either VPA or PH...

journal_title：Acta neurologica Scandinavica

authors： Gilad R,Izkovitz N,Dabby R,Rapoport A,Sadeh M,Weller B,Lampl Y

更新日期：2008-11-01 00:00:00

abstract：:In Sweden, the annual incidence of surgery for hydrocephalus was 3.4 per 100,000 adults between the years 1996 and 1998. The most common indication for surgery was normal pressure hydrocephalus (NPH; 47%), followed by high-pressure hydrocephalus (27%). Seventy-three percent of the patients had communicating hydrocepha...

journal_title：Acta neurologica Scandinavica

authors： Tisell M,Höglund M,Wikkelsø C

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Some recent studies have found an association between foetal malformations in earlier antiepileptic drug (AED)-exposed pregnancies and an increased hazard of such malformations in subsequent pregnancies. We investigated this matter further, and also considered the possible role of spontaneous abortions in pr...

journal_title：Acta neurologica Scandinavica

authors： Vajda FJ,O'Brien TJ,Graham JE,Hitchcock AA,Lander CM,Eadie MJ

更新日期：2017-03-01 00:00:00

abstract：:Intrathecal IgG synthesis and CSF oligoclonal bands were reexamined after 18-24 months in 66 patients with multiple sclerosis; 40 of them received azathioprine (AZA) 2.5 mg/Kg/die; all received a course of dexamethasone (DEXA) during clinical relapses. The IgG Index was significantly reduced in the group treated with ...

journal_title：Acta neurologica Scandinavica

authors： Caputo D,Zaffaroni M,Ghezzi A,Cazzullo CL

更新日期：1987-02-01 00:00:00

abstract：OBJECTIVES:Analysis of the CTG-repeat number and three biallelic markers, Alu(+/-), HinfI(+/-), and TaqI(+/-), in the DMPK gene in healthy and myotonic dystrophy type 1 (DM1) Serbian individuals. Also, the consideration of haplotypes in the light of the proposed models of CTG-repeat evolution and origin of the DM1 muta...

journal_title：Acta neurologica Scandinavica

authors： Krndija D,Savić D,Mladenović J,Rakocević-Stojanović V,Apostolski S,Todorović S,Romac S

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVES:The objective was to investigate the incidence of multiple sclerosis (MS) as well as estimate the prevalence as of 1 January 2014 in the southeastern Norwegian county of Buskerud. MATERIALS AND METHODS:All patients with MS living in Buskerud county in Norway between 01 January 2003 and 01 January 2014 were ...

journal_title：Acta neurologica Scandinavica

authors： Simonsen CS,Edland A,Berg-Hansen P,Celius EG

更新日期：2017-04-01 00:00:00

abstract：:Taurine content of 199 clinical muscle biopsies was determined and correlated to histometric data of 121 cases. Taurine concentration in muscles was markedly dependent on fiber type distribution, taurine being more abundant in the slow, oxidative type 1 fibers than in the type 2 fibers. Taurine concentration rose slig...

journal_title：Acta neurologica Scandinavica

authors： Airaksinen EM,Paljärvi L,Partanen J,Collan Y,Laakso R,Pentikäinen T

更新日期：1990-01-01 00:00:00

abstract：:The effects of bromocriptine in patients with Parkinson's disease manifesting various problems in levodopa therapy were tested in a double-blind manner with the collaboration of 59 institutions. The slow and low principle was in part adopted. Either bromocriptine or placebo was added to levodopa. Twenty-nine % of the ...

journal_title：Acta neurologica Scandinavica

authors： Toyokura Y,Mizuno Y,Kase M,Sobue I,Kuroiwa Y,Narabayashi H,Uono M,Nakanishi T,Kameyama M,Ito H

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Some previous studies reported an independent association between uric acid and coronary artery disease, while little is known on the association among uric acid and carotid artery disease (CAD). To address this issue, we investigated the association between CAD and higher uric acid level because...

journal_title：Acta neurologica Scandinavica

authors： Kumral E,Karaman B,Orman M,Kabaroglu C

更新日期：2014-07-01 00:00:00

abstract：:In a double-blind crossover pilot study with placebo, choline chloride, the physiologic precursor of acetylcholine, was tested in six patients with cerebellar ataxia. Neither subjectively nor objectively could any statistical significant difference be demonstrated. ...

journal_title：Acta neurologica Scandinavica

authors： Sehested P,Lund HI,Kristensen O

更新日期：1980-08-01 00:00:00

abstract：:Brivaracetam (BRV) is a new antiseizure medication (ASM) that is currently approved for adjunctive treatment in patients with focal onset seizures. Similarly to levetiracetam (LEV), BRV works by binding SV2A vesicles with a high affinity and a linear pharmacokinetic profile. Retrospective studies and randomized clinic...

journal_title：Acta neurologica Scandinavica

authors： Verrotti A,Grasso EA,Cacciatore M,Matricardi S,Striano P

更新日期：2020-09-23 00:00:00

abstract：OBJECTIVES:To examine the factors that influence acute and total length of stay (LOS) for stroke patients. MATERIALS AND METHODS:The basis of this investigation was a population-based cohort of first-ever stroke patients (n = 388). Subjects were survivors of the initial hospitalization (n = 295). Age, sex, social fact...

journal_title：Acta neurologica Scandinavica

authors： Appelros P

更新日期：2007-07-01 00:00:00

abstract：:To clarify the central nervous and the cardiovascular mechanisms mediating the Cushing response (CR) during intracranial hypertension, the effects of continuous and prolonged expansion of an epidural supratentorial balloon was studied in six dogs. Regional cerebral blood flow, cardiac output, extracerebral tissue bloo...

journal_title：Acta neurologica Scandinavica

authors： Schrader H,Hall C,Zwetnow NN

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVES:Hospital admission in otherwise healthy patients following a first unprovoked seizure is controversial. We aimed to evaluate the influence of admission in a neurology department on the identification of risk factors for seizure recurrence in patients with a first unprovoked seizure. MATERIALS AND METHODS:We...

journal_title：Acta neurologica Scandinavica

authors： Goldberg I,Neufeld MY,Auriel E,Gandelman-Marton R

更新日期：2013-07-01 00:00:00

abstract：:Regional cerebral blood flow (rCBF) was measured in 23 patients with brain tumors using the 133Xe intra-carotid injection method and a 254 channel gamma camera. The glioblastomas (4) and astrocytomas (4) all showed hyperemia in the tumor and tumor-near region. This was also seen in several meningiomas (4 of 7 cases) i...

journal_title：Acta neurologica Scandinavica

authors： Kuroda K,Skyhøj Olsen T,Lassen NA

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:Elevated levels of the cerebrospinal fluid (CSF) neuronal injury markers (neurofilament light chain [NF-L] and total tau protein [t-tau]) and of the astroglial marker glial fibrillary acidic protein (GFAP) are found in etiologically different neurological disorders affecting the peripheral and the central ne...

journal_title：Acta neurologica Scandinavica

authors： Constantinescu R,Mahamud U,Constantinescu C,Eriksson B,Novakova L,Olsson B,Rosengren L,Blennow K,Axelsson M

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVES:To investigate efficacy and safety of entacapone across phase III studies in Parkinson's disease (PD) with wearing-off symptoms. METHODS:Retrospective, pooled analysis of four phase 3 randomized, double-blind, placebo-controlled studies with entacapone. RESULTS:475 of 808 patients with PD received entacapo...

journal_title：Acta neurologica Scandinavica

authors： Kuoppamäki M,Vahteristo M,Ellmén J,Kieburtz K

更新日期：2014-10-01 00:00:00

abstract：:Two cases of increased intracranial pressure associated with lumbar intraspinal tumours are reported. On the basis of protein investigations and constant flow infusion manometric tests, the pathophysiology of the increased intracranial pressure is discussed. It is demonstrated that protein macromolecules leak from the...

journal_title：Acta neurologica Scandinavica

authors： Borgesen SE,Sorensen SC,Olesen J,Gjerris F

更新日期：1977-09-01 00:00:00

abstract：:Although intravenous (i.v.) heparin is widely used as the first line treatment for cerebral venous and sinus thrombosis (CVST), the most appropriate therapy for this disease is still controversial. We report 2 cases of CVST who were successfully treated by means of loco-regional thrombolysis with urokinase. In the fir...

journal_title：Acta neurologica Scandinavica

authors： Buccino G,Scoditti U,Pini M,Menozzi R,Piazza P,Zuccoli P,Mancia D

更新日期：2001-01-01 00:00:00

abstract：:Serum and CSF from 53 vascular dementia (VD) patients and 50 controls were analysed to investigate the possibility of an intrathecal synthesis of IgG, defined as an elevated IgG index (greater than or equal to 7) and/or presence of oligoclonal IgG in cerebrospinal fluid (CSF), but not in serum. Five (9%) patients and ...

journal_title：Acta neurologica Scandinavica

authors： Wallin A,Blennow K,Fredman P,Gottfries CG,Karlsson I,Svennerholm L

更新日期：1990-02-01 00:00:00

abstract：:Five patients with chronic progressive multiple sclerosis (MS) and three control patients with lumbar disc herniation were treated with dexamethazone during 14 days. The effect on peripheral blood T-cell subsets and on the proliferative response of peripheral blood mononuclear cells (PBMC) to pokeweed mitogen (PWM) an...

journal_title：Acta neurologica Scandinavica

authors： Salmaggi A,Baldetorp B,Milanese C,Nespolo A,Parma R,Sandberg-Wollheim M

更新日期：1991-08-01 00:00:00

abstract：:Muscle cramps are involuntary, painful, sudden contractions of the skeletal muscles. They are present in normal subjects under certain conditions (during a strong voluntary contraction, sleep, sports, pregnancy) and in several pathologies such as myopathies, neuropathies, motoneuron diseases, metabolic disorders, hydr...

journal_title：Acta neurologica Scandinavica

authors： Parisi L,Pierelli F,Amabile G,Valente G,Calandriello E,Fattapposta F,Rossi P,Serrao M

更新日期：2003-03-01 00:00:00

abstract：:The effect of seizures on synthesis of the polyadenylic acid (poly(A]-containing messenger RNA (mRNA) isolated from brain polysomes in a genetically seizure-susceptible E1 mouse was studied in vivo. The seizure in the E1 mice was induced by tossed-up stimulation. Immediately after the seizure ceased, the labeled oroti...

journal_title：Acta neurologica Scandinavica

authors： Yamagami S,Onishi H,Kawakita Y

更新日期：1989-10-01 00:00:00

abstract：:We present 2 sibs with autosomal recessive spastic paraparesis and severe amyotrophy of the distal limb muscles. Elaborate neurophysiologic studies disclosed slight to moderate slowing of motor conduction, moderate to severe reduction of motor action potentials, denervation potentials, and increased distal motor laten...

journal_title：Acta neurologica Scandinavica

authors： Bruyn RP,Scheltens P,Lycklama à Nijeholt J,de Jong JM

更新日期：1993-06-01 00:00:00