Azathioprine reduces intrathecal IgG synthesis in multiple sclerosis.

abstract：BACKGROUND:Both pregnancy and high vitamin D concentration seem to generate a protective environment against multiple sclerosis (MS) relapses. Longitudinal case-control analysis of vitamin D concentrations during pregnancy and lactation of MS mothers is lacking. AIMS OF THE STUDY:To examine serum 25-hydroxyvitamin-D3 ...

journal_title：Acta neurologica Scandinavica

authors： Jalkanen A,Kauko T,Turpeinen U,Hämäläinen E,Airas L

更新日期：2015-01-01 00:00:00

abstract：:There has been considerable interest in the possible association between impaired glucose tolerance (IGT) and neuropathy. A systematic literature search (Medline) and review was here performed. Twenty-three studies were evaluated. Fourteen investigated for the presence of neuropathy in patients with IGT. Nine studied ...

journal_title：Acta neurologica Scandinavica

authors： Rajabally YA

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVES:To report three cases of premature death in juvenile myoclonic epilepsy (JME), a benign form of idiopathic generalized epilepsy (IGE) in which no case of epilepsy-related death has been reported. MATERIAL AND METHODS:We retrospectively analyzed all medical records of JME patients first referred to two epile...

journal_title：Acta neurologica Scandinavica

authors： Genton P,Gelisse P

更新日期：2001-09-01 00:00:00

abstract：:Lumbar cerebrospinal fluid (CSF) from 30 cases of subacute sclerosing panencephalitis (SSPE) was studied for total protein and protein electrophoresis. Total CSF protein values were normal in almost all the cases, but the gamma-globulin was increased and had an oligoclonal morphology in all the cases. Absolute and rel...

journal_title：Acta neurologica Scandinavica

authors： Silva CA,Rio ME,Cruz C

更新日期：1981-04-01 00:00:00

abstract：:Three patients with wasting confined to a single lower limb are reported. The characteristic features were: sporadic occurrence, insidious onset with slow progression and in 2 cases arrested course for at least 4 years, wasting out of proportion with disability, absence of sensory, pyramidal tract or bulbar signs. CK,...

journal_title：Acta neurologica Scandinavica

authors： Uncini A,Servidei S,Delli Pizzi C,Cutarella R,Di Muzio A,Gambi D,Tonali P

更新日期：1992-06-01 00:00:00

abstract：OBJECTIVE:The coincidence of coagulatopathy and chronic subdural haematoma (CSH) requires correction of coagulation to facilitate surgery. We investigated the correlation between coagulopathy and outcome in CSH patients. MATERIAL AND METHODS:We analysed past medical history, surgical treatment and coagulation paramete...

journal_title：Acta neurologica Scandinavica

authors： König SA,Schick U,Döhnert J,Goldammer A,Vitzthum HE

更新日期：2003-02-01 00:00:00

abstract：:The risk of stroke related to asymptomatic carotid artery stenosis is known to be increased in high-grade or rapidly progressive stenosis. Information of the prevalence in the general population is required for the recommendation of screening methods to detect patients needing prophylactic treatment. We studied the pr...

journal_title：Acta neurologica Scandinavica

authors： Harer C,Gusev EI

更新日期：1996-04-01 00:00:00

abstract：:A CSF Poly(C)-avid ribonuclease (RNase) activity was determined in serum and CSF of 11 controls and 75 neurological patients (34 multiple sclerosis (MS), 18 infectious processes and 23 other neurological diseases (OND]. In controls, the blood-CSF ratio of RNase activity is low. This fact and the absence of correlation...

journal_title：Acta neurologica Scandinavica

authors： Allinquant B,Musenger C,Schuller E

更新日期：1984-07-01 00:00:00

abstract：OBJECTIVES:Although there is growing evidence for a relation between Parkinson syndrome (PS) and mitochondriopathy (MCP), little is known about the frequency of PS in MCP. MATERIAL AND METHODS:This study assessed the frequency of PS in patients with MCP, the phenotype of these patients, and their response to anti-Park...

journal_title：Acta neurologica Scandinavica

authors： Finsterer J

更新日期：2002-05-01 00:00:00

abstract：:The relation between angiographically determined cerebral vasospasm following a subarachnoid hemorrhage and regional cerebral blood flow (CBF) was studied in 63 investigations of 45 patients. The CBF was measured using the intra-arterial 133-Xe clearance technique within one hour of angiography. A positive correlation...

journal_title：Acta neurologica Scandinavica

authors： Jakobsen M,Overgaard J,Marcussen E,Enevoldsen EM

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVES:Mutations in the p150 subunit of the axonal transport protein dynactin (DCTN1) have been reported in patients with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Given the common features of neurodegeneration in multiple sclerosis (MS), FTD and ALS, sequence variants of the DCTN1 gene...

journal_title：Acta neurologica Scandinavica

authors： Münch C,Meyer R,Linke P,Meyer T,Ludolph AC,Haas J,Hemmer B

更新日期：2007-10-01 00:00:00

abstract：INTRODUCTION:The objective of this study was to describe facial myokymia in experimental animals accompanying kainic acid affects on facial motor neurons. MATERIAL & METHODS:Anesthetized cats were injected with kainic acid into the pons adjacent to the facial nucleus. Facial movements appeared shortly after the inject...

journal_title：Acta neurologica Scandinavica

authors： Zaaroor M,Starr A

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVES:Many studies have shown that nitric oxide (NO) and growth factors including insulin growth factors (IGFs) may be involved in the pathogenesis of multiple sclerosis (MS) and neurodegenerative diseases. Our previous studies suggested a relationship between cerebrospinal fluid (CSF) NO metabolites (nitrates and...

journal_title：Acta neurologica Scandinavica

authors： Pirttilä T,Vanhatalo S,Turpeinen U,Riikonen R

更新日期：2004-05-01 00:00:00

abstract：:Status epilepticus (SE) describes an enduring epileptic state during which seizures are unremitting and tend to be self-perpetuating. We describe the clinical phases of generalized convulsive SE, impending SE, established SE, and subtle SE. We discuss the physiological and biochemical cascades which characterize self-...

journal_title：Acta neurologica Scandinavica

authors： Chen JW,Naylor DE,Wasterlain CG

更新日期：2007-04-01 00:00:00

abstract：:Previously we have shown low levels of dystrophin immunoreactivity in muscle from patients with DMD. According to the "frame-shift hypothesis" DMD muscle should not synthesize any dystrophin through to the C-terminus and it has been suggested that the protein detected is not dystrophin, but a related autosomal homolog...

journal_title：Acta neurologica Scandinavica

authors： Nicholson LV,Johnson MA,Davison K,O'Donnell E,Falkous G,Barron M,Harris JB

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Idiopathic Parkinson's disease (IPD) is characterized by the clinical motor symptoms of hypokinesia, rigidity, and tremor. Apart from these motor symptoms, cognitive deficits often occur in IPD. The positive effect of cholinesterase inhibitors on cognitive deficits in IPD and findings of earlier molecular im...

journal_title：Acta neurologica Scandinavica

authors： Lorenz R,Samnick S,Dillmann U,Schiller M,Ong MF,Faßbender K,Buck A,Spiegel J

更新日期：2014-09-01 00:00:00

abstract：:N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, MPTP, is a neurotoxic substance known to induce a parkinsonian syndrome in primates. The distribution of intravenously injected 11C-labelled MPTP (11C-MPTP) in the head of Rhesus monkeys was studied by means of positron emission tomography, PET. The influence of pretreatme...

journal_title：Acta neurologica Scandinavica

authors： Hartvig P,Larsson BS,Lindberg BS,Oreland L,Gullberg P,Långström B,Rimland A,Lundqvist H,Malmborg P,Lindquist NG

更新日期：1986-07-01 00:00:00

abstract：:This article reports the case of a man who developed a pure motor paraplegia following epidural anesthesia with a pattern of slow recovery over subsequent months. Reviewing the available literature on post-epidural paraplegia we noted a number of potential etiologies and analyzed their role in its causation. On the ba...

journal_title：Acta neurologica Scandinavica

authors： Skouen JS,Wainapel SF,Willock MM

更新日期：1985-10-01 00:00:00

abstract：OBJECTIVES:"Epileptic dementia" is reported in adults with childhood-onset refractory epilepsy. Cognitive deterioration can also occur in a "second-hit model". MATERIALS AND METHODS:We studied the clinical and neuropsychological characteristics of patients with cognitive deterioration (≥1 SD discrepancy between curren...

journal_title：Acta neurologica Scandinavica

authors： Breuer LEM,Grevers E,Boon P,Bernas A,Bergmans JWM,Besseling RMH,Klooster DCW,de Louw A,Mestrom RMC,Vonck K,Zinger S,Aldenkamp AP

更新日期：2017-07-01 00:00:00

abstract：:The immediate effects of selective sympathetic and somatic blockades on pain and tactile allodynia in 12 patients with long-standing ophthalmic or high cervical postherpetic neuralgia were compared. For the duration of the somatic blockade, pain was completely abolished in 11 patients and allodynia in 8 patients. In c...

journal_title：Acta neurologica Scandinavica

authors： Nurmikko T,Wells C,Bowsher D

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune disorder of the central nervous system (CNS). Interleukin (IL)-6 and IL-17A may play important roles in the pathogenesis of this disease. High-mobility group box protein 1 (HMGB1), a small but highly conserved ubiquitous protein, is rec...

journal_title：Acta neurologica Scandinavica

authors： Ai P,Zhang X,Xie Z,Liu G,Liu X,Pan S,Wang H

更新日期：2018-02-01 00:00:00

abstract：:Electrophysiological examinations were done on 20 patients aged 40-71 years with recently diagnosed high grade non-Hodgkin's lymphomas. General chemotherapy and intrathecal chemotherapy in order to prevent central nervous system (CNS) involvement were begun. On the first day of chemotherapeutic cycle patients received...

journal_title：Acta neurologica Scandinavica

authors： Grzelec H,Fryze C,Nowacki P,Zdziarska B

更新日期：1996-10-01 00:00:00

abstract：:The in vitro protein synthetic capactiy of brain slices from guinea-pigs in the late stage (17-18 days post-induction) of experimental allergic encephalomyelitis was increased over that of Freund's adjuvant injected controls, as determined by the rate of (14C)-leucine incorporation into both tris-soluble and tris-inso...

journal_title：Acta neurologica Scandinavica

authors： Babitch JA,Blomstrand C,Hamberger A

更新日期：1975-03-01 00:00:00

abstract：:The clinical features of multiple sclerosis (MS) in north-east Scotland have been examined along with an epidemiological study to determine the prevalence of the disease on 1st December, 1970. Patient information was collected from all available diagnostic indices, both retrospectively and prospectively from 1965. Eve...

journal_title：Acta neurologica Scandinavica

authors： Shepherd DI

更新日期：1979-10-01 00:00:00

abstract：:Demented patients with Alzheimer's disease (AD) (n = 67), multi-infarct dementia (MID) (n = 77) and probable vascular dementia (PVD) (n = 45) were studied with electroencephalography (EEG). All patients underwent a routine EEG examination and quantitative EEG was recorded from 14 patients with AD, 20 with MID, and 12 ...

journal_title：Acta neurologica Scandinavica

authors： Erkinjuntti T,Larsen T,Sulkava R,Ketonen L,Laaksonen R,Palo J

更新日期：1988-01-01 00:00:00

abstract：:Mitochondrial DNA (mtDNA) deletions have been noted in small quantities in a handful of atypical cases of myotonic dystrophy and there are clinical and pathological parallels between this autosomal dominant disease and certain mitochondrial myopathies where such deletions are well recognised. We studied 20 individuals...

journal_title：Acta neurologica Scandinavica

authors： Thyagarajan D,Byrne E,Noer S,Lertrit P,Utthanophol P,Kapsa R,Marzuki S

更新日期：1993-01-01 00:00:00

abstract：:We investigated the types of syndrome, location, size and presumed causes of 72 patients with acute capsular lacunar infarction. Clinical syndromes were classified into pure motor hemiparesis (PM), sensorimotor stroke (SM) and ataxic hemiparesis (AH). Lesion sizes of AH were significantly smaller than those of PM (p <...

journal_title：Acta neurologica Scandinavica

authors： Tei H,Uchiyama S,Maruyama S

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:To assess hemispheric differences in the duration of focal onset seizures and its association with clinical and demographic factors. METHODS:A retrospective analysis was performed on adult patients with drug-resistant unifocal epilepsy, who underwent intracranial EEG recording between 01/2006 and 06/2016. Se...

journal_title：Acta neurologica Scandinavica

authors： Seethaler M,Lauseker M,Ernst K,Rémi J,Vollmar C,Noachtar S,Kaufmann E

更新日期：2020-10-04 00:00:00

abstract：OBJECTIVES:We describe 2 patients with epilepsy as an early manifestation of late onset metachromatic leukodystrophy (MLD). METHODS AND RESULTS:The first patient presented with epileptic seizures at the age of 34 years while neurological and cognitive abnormalities appeared later. MRI findings were compatible with leu...

journal_title：Acta neurologica Scandinavica

authors： Bostantjopoulou S,Katsarou Z,Michelakaki H,Kazis A

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVES:To compare intravenous phenytoin (PHT) and intravenous lacosamide (LCM) for treatment of status epilepticus after failure of the first and second drug. METHODS:We retrospectively identified patients from a large community hospital in northern Germany who had been diagnosed with SE between August 2008 and De...

journal_title：Acta neurologica Scandinavica

authors： Kellinghaus C,Berning S,Stögbauer F

更新日期：2014-05-01 00:00:00