Dystrophin or a "related protein" in Duchenne muscular dystrophy?

abstract：:Cerebral blood flow (CBF) was studied in 4 patients with acute reversible ischemia (RIND). To test the ischemic areas' vasoreactivity, CBF was measured by the Xenon-133 inhalation method, before and after acetazolamide injected intravenously. At the baseline CBF study, 3 patients presented hypoperfused areas while one...

journal_title：Acta neurologica Scandinavica

authors： Di Piero V,Pozzilli C,Pantano P,Grasso MG,Fieschi C

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:There has been a long-standing interest in the possible role of the hippocampus in autism and both postmortem brain and neuroimaging studies have documented varying abnormalities in this limbic system structure. AIMS:This study investigates the density of subsets of hippocampal interneurons, immunostained w...

journal_title：Acta neurologica Scandinavica

authors： Lawrence YA,Kemper TL,Bauman ML,Blatt GJ

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:To examine differences in cerebrovascular reactivity between multi-infarct and Alzheimer types of dementia. PATIENTS AND METHODS:Using transcranial Doppler, measurements of flow velocity in the middle cerebral arteries during apnea, thumb-to-finger opposition and verbal and design discrimination tasks were ...

journal_title：Acta neurologica Scandinavica

authors： Matteis M,Silvestrini M,Troisi E,Bragoni M,Vernieri F,Caltagirone C

更新日期：1998-06-01 00:00:00

abstract：:The occurrence of cerebral infarction in patients with transient global amnesia (n = 43) was evaluated by CT scan and compared to that of patients with transient ischemic attacks (TIA) (n = 58) and with no neurological disease (n = 52). Significant differences were demonstrated between TGA and TIA patients in relation...

journal_title：Acta neurologica Scandinavica

authors： Matias-Guiu J,Colomer R,Segura A,Codina A

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVES:The pathophysiology of migraine headaches is not clearly understood yet. The dopaminergic system has been hypothesized to be involved in migraine pathogenesis. The aim of this study was to investigate catechol-O-methyltransferase (COMT) polymorphisms and chronic headaches. We analyzed five single nucleotide ...

journal_title：Acta neurologica Scandinavica

authors： Takigawa H,Kowa H,Nakashima K

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:LMNB1-related autosomal dominant leukodystrophy is caused by an overexpression of the protein lamin B1, usually due to a duplication of the LMNB1 gene. Symptoms start in 5th to 6th decade. This slowly progressive disease terminates with death. We studied brain glucose metabolism in this disease using 18 F-flu...

journal_title：Acta neurologica Scandinavica

authors： Finnsson J,Lubberink M,Savitcheva I,Fällmar D,Melberg A,Kumlien E,Raininko R

更新日期：2019-02-01 00:00:00

abstract：:Symptoms of acute renal failure were observed in an anorexia patient who had a history of frequent vomiting. The acute renal failure might have resulted from rhabdomyolysis subsequent to a disturbance of electrolyte balance. This acute renal failure might have resulted in death if not treated. We postulate that even a...

journal_title：Acta neurologica Scandinavica

authors： Abe K,Mezaki T,Hirono N,Udaka F,Kameyama M

更新日期：1990-01-01 00:00:00

abstract：:A group of asymptomatic HIV-infected patients (CDC II and III) was followed-up over a two year period with semi-annual neuropsychological testing. Of the total sample of 36 subjects, all were retested at test two (T2), 19 at test three (T3) and 13 at test four (T4). A subgroup of subjects was further tested on a simpl...

journal_title：Acta neurologica Scandinavica

authors： Karlsen NR,Reinvang I,Frøland SS

更新日期：1993-02-01 00:00:00

abstract：:A 23-year-old patient suffering from mental deterioration was referred for CT study following her first epileptic fit. The study disclosed generalized atrophy and diffuse symmetric white matter hypodensities. Similar findings were found in her 13-year-old retarded sister. The diagnosis of metachromatic leukodystrophy ...

journal_title：Acta neurologica Scandinavica

authors： Reider-Grosswasser I,Bornstein N

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study is to estimate the risk of hip fracture after first-ever stroke, using a nationwide population-base data set and a retrospective cohort design. MATERIALS AND METHODS:The cohort study involved 18,413 patients surviving a first-ever stroke during the 12-year period from 1997 to 2008. Ano...

journal_title：Acta neurologica Scandinavica

authors： Lin HL,Lin HC,Tseng YF,Liao HH,Worly JA,Pan CY,Hsu CY

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the epidemiological and clinical features of motor neuron disease (MND) in a region (835,000 inhabitants) of south-western Greece. PATIENTS AND METHODS:The medical records of all patients diagnosed with adult-onset MND at the Department of Neurology of the University Hospital of Patras from 1990 ...

journal_title：Acta neurologica Scandinavica

authors： Argyriou AA,Polychronopoulos P,Papapetropoulos S,Ellul J,Andriopoulos I,Katsoulas G,Salakou S,Chroni E

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to examine the association between the frequency of alcohol consumption and stroke mortality among eastern Finnish men. MATERIAL AND METHODS:This study is a population-based sample of men with an average follow-up of 20.2 years. A total of 2609 men with no history of stroke at ...

journal_title：Acta neurologica Scandinavica

authors： Rantakömi SH,Kurl S,Sivenius J,Kauhanen J,Laukkanen JA

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVES:To report a peculiar observation of a patient who developed a psychomotor inhibition state after a rapid cessation of lamotrigine (LTG). RESULTS:This man was referred to us at the age of 26 years for presurgical evaluation. His treatment [valproate (VPA), 1200 mg/day and LTG, 200 mg/day] was quickly decreas...

journal_title：Acta neurologica Scandinavica

authors： Gelisse P,Kissani N,Crespel A,Jafari H,Baldy-Moulinier M

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:To examine, in a randomized, controlled, single blinded trial, the efficacy of a soft hand brace and a wrist splint for carpal tunnel syndrome (CTS). METHODS:We randomized 120 patients with CTS into a group wearing the soft hand brace MANU and into another group wearing the wrist splint CAMP TIELLE at night ...

journal_title：Acta neurologica Scandinavica

authors： De Angelis MV,Pierfelice F,Di Giovanni P,Staniscia T,Uncini A

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:The coincidence of coagulatopathy and chronic subdural haematoma (CSH) requires correction of coagulation to facilitate surgery. We investigated the correlation between coagulopathy and outcome in CSH patients. MATERIAL AND METHODS:We analysed past medical history, surgical treatment and coagulation paramete...

journal_title：Acta neurologica Scandinavica

authors： König SA,Schick U,Döhnert J,Goldammer A,Vitzthum HE

更新日期：2003-02-01 00:00:00

abstract：:The phosphomannosyl receptor system is responsible for both the receptor-mediated endocytosis and the intracellular transport of lysosomal enzymes. In the present study this receptor system was examined in affected muscles of patients with various neuromuscular diseases. The total activity of beta-N-acetyl-glucosamini...

journal_title：Acta neurologica Scandinavica

authors： Salminen A,Marjomäki V,Tolonen U,Myllylä VV

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:One of recent interesting hypotheses of transient global amnesia (TGA) pathophysiology is the preexisting vulnerability of the memory network in patients with TGA. AIM OF THE STUDY:To verify the hypothesis that patients with recurrent amnestic attacks may have more disrupted structural connectivity than pat...

journal_title：Acta neurologica Scandinavica

authors： Moon Y,Moon WJ,Han SH

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:To describe spinal epidural abscess after treatment with rituximab. METHODS:Report of a new case of cervical epidural spinal abscess after treatment with rituximab and review of the literature. RESULTS:Biologic agents are associated with an increased risk of serious infections, there are only few reports of...

journal_title：Acta neurologica Scandinavica

authors： Avila JD,Živković S

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:Dopamine neurotransmission is a critical factor for executive function, which is controlled by the prefrontal cortex in humans. Although the contribution of genetic factors to the regulation of brain dopaminergic activity is widely acknowledged, identification of a genotype-phenotype association has not yet ...

journal_title：Acta neurologica Scandinavica

authors： Mitaki S,Isomura M,Maniwa K,Yamasaki M,Nagai A,Nabika T,Yamaguchi S

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:Stimulation of the subthalamic nucleus (STN-DBS) is an established treatment with long-term beneficial effects on motor symptoms in patients with Parkinson's disease (PD). The long-term development of non-motor problems after STN-DBS is not fully understood. In this study, we have studied how non-motor probl...

journal_title：Acta neurologica Scandinavica

authors： Lilleeng B,Gjerstad M,Baardsen R,Dalen I,Larsen JP

更新日期：2015-10-01 00:00:00

abstract：:IgG and IgM concentrations in tears of multiple sclerosis patients (n = 38) are increased compared to normal controls (n = 23). The occurrence of oligoclonal tear IgG bands (7.9%)--as determined by immunoblotting--did not differ between groups. Our findings suggest an altered reactivity of the secretory immune system ...

journal_title：Acta neurologica Scandinavica

authors： Liedtke W,Weller M,Wiethölter H,Dichgans J

更新日期：1992-03-01 00:00:00

abstract：:Nervous system involvement in patients with AIDS is frequent either due to direct infection by the HIV-1 or to opportunistic infections or neoplasms. In the present study we evaluate the epidemiologic characteristics of patients in whom the first AIDS manifestation was an indicative neurologic disease (IND) and the in...

journal_title：Acta neurologica Scandinavica

authors： Casabona J,Sánchez E,Graus F,Abós J,Segura A

更新日期：1991-07-01 00:00:00

abstract：OBJECTIVES:To measure gait and postural stability by objective methods in spastic MS patients and to evaluate the effect of baclofen on gait and postural stability. PATIENTS AND METHODS:Fourteen spastic MS patients were examined in a placebo controlled double-blind, cross-over trial of oral baclofen treatment. The gai...

journal_title：Acta neurologica Scandinavica

authors： Orsnes GB,Sørensen PS,Larsen TK,Ravnborg M

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVES:The Flt3 ligand (FL) is a cytokine with a neurotrophic and antiapoptotic activity in the central nervous system that induces the survival of neurons. The aim of the study was to measure levels of FL in amyotrophic lateral sclerosis (ALS) patients. MATERIALS AND METHODS:The study involved 23 ALS patients and...

journal_title：Acta neurologica Scandinavica

authors： Iłzecka J

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid artery disease (CAD) is able to critically impair cerebral autoregulation which increases the risk for stroke. As therapeutic strategy largely depends on the degree of CAD, we investigated whether this gradation is also related to significant changes in autoregulatory capacity. We applied...

journal_title：Acta neurologica Scandinavica

authors： Haubrich C,Klemm A,Diehl RR,Möller-Hartmann W,Klötzsch C

更新日期：2004-03-01 00:00:00

abstract：:An EEG study of 64 Danish Turner girls and age-matched controls was made. The characteristic findings in the basic EEG rhythms of Turner girls were: 1) alpha activity of more rapid frequency (10.5+ Hz), lower amplitude (-20 microV, lower amount (-30%) and diffuse areas, 2) beta activity of slower frequency (14-18 Hz),...

journal_title：Acta neurologica Scandinavica

authors： Tsuboi T,Nielsen J

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVE:To study the relationship between cerebral hemodynamics and clinical performance in normal pressure hydrocephalus (NPH), before and after surgery. MATERIAL AND METHODS:Ten patients were studied prospectively before and 3 months after shunt surgery by means of transcranial Doppler (TCD). Clinical performance ...

journal_title：Acta neurologica Scandinavica

authors： Bakker SL,Boon AJ,Wijnhoud AD,Dippel DW,Delwel EJ,Koudstaal PJ

更新日期：2002-09-01 00:00:00

abstract：:Epileptic seizures are refractory to treatment in approximately one-third of patients despite the recent introduction of many newer antiepileptic drugs (AEDs). Development of novel AEDs therefore remains a high priority. Perampanel is a first-in-class non-competitive selective AMPA receptor antagonist with a unique me...

journal_title：Acta neurologica Scandinavica

authors： Tsai JJ,Wu T,Leung H,Desudchit T,Tiamkao S,Lim KS,Dash A

更新日期：2018-04-01 00:00:00

abstract：:Fifteen epileptic patients had their dose of anticonvulsant drugs changed twice, each time by 30-50 per cent of the initial medication. Before the dose change, the patients were given six especially adapted mental performance tests, which were designed to measure vigilance, reaction time and certain aspects of memory....

journal_title：Acta neurologica Scandinavica

authors： Dekaban AS,Lehman EJ

更新日期：1975-10-01 00:00:00

abstract：UNLABELLED:The basal ganglia are thought to be involved in the primary dystonias, largely because of the repeated demonstration of neuropathological changes in these nuclei in the secondary dystonias. A hyperactivity of a network involving basal ganglia has been suggested in experimental animal dystonia. To test this h...

journal_title：Acta neurologica Scandinavica

authors： Galardi G,Perani D,Grassi F,Bressi S,Amadio S,Antoni M,Comi GC,Canal N,Fazio F

更新日期：1996-09-01 00:00:00