Immunological abnormalities in the tears of multiple sclerosis patients.

Abstract:

:IgG and IgM concentrations in tears of multiple sclerosis patients (n = 38) are increased compared to normal controls (n = 23). The occurrence of oligoclonal tear IgG bands (7.9%)--as determined by immunoblotting--did not differ between groups. Our findings suggest an altered reactivity of the secretory immune system in MS patients, but did not differ from findings in patients with eye affections or wearing hard contact lenses.

journal_name

Acta Neurol Scand

authors

Liedtke W,Weller M,Wiethölter H,Dichgans J

doi

10.1111/j.1600-0404.1992.tb04034.x

subject

Has Abstract

pub_date

1992-03-01 00:00:00

pages

228-30

issue

3

eissn

0001-6314

issn

1600-0404

journal_volume

85

pub_type

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