Coagulopathy and outcome in patients with chronic subdural haematoma.

Abstract:

OBJECTIVE:The coincidence of coagulatopathy and chronic subdural haematoma (CSH) requires correction of coagulation to facilitate surgery. We investigated the correlation between coagulopathy and outcome in CSH patients. MATERIAL AND METHODS:We analysed past medical history, surgical treatment and coagulation parameters of 114 patients. RESULTS:Coagulation disorders were found in 42%. Preoperative treatment with prothrombin complex concentrate was necessary in 14%. A significant difference (P < 0.05) of the preoperative level of platelets was found between recurrent CSH and non-recurrent group. Totally, we had to perform re-operations in 17.5%. Eighty-one patients presented with Glasgow coma scale (GCS) > or = 13. After surgery GCS was > or = 13 in n = 92. There was an improvement of GCS in 46 cases, 61 patients maintained GCS score levels. Outcome was significantly worse in the alcoholic group (P < 0.001), and in the recurrent group (P < 0.05). In patients with substitution of coagulation factors, outcome was worse in the group with post-operative substitution only (P < 0.05). CONCLUSION:In CSH, the coagulation parameters and a subtle correction of coagulation are of special interest, regarding the worse outcome in patients with recurrent CSH and in those requiring post-operative substitution.

journal_name

Acta Neurol Scand

authors

König SA,Schick U,Döhnert J,Goldammer A,Vitzthum HE

doi

10.1034/j.1600-0404.2003.01340.x

subject

Has Abstract

pub_date

2003-02-01 00:00:00

pages

110-6

issue

2

eissn

0001-6314

issn

1600-0404

pii

1o340

journal_volume

107

pub_type

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