Genetic factors in temporal lobe epilepsy.

Abstract:

:Genetic investigation of 74 patients with temporal lobe epilepsy, resistant to medication, who underwent unilateral temporal lobectomy 1960-1969. Thirty per cent had a positive family history of epilepsy; 49 per cent of other neurological diseases; and 46 per cent of major psychiatric disorders. Neither of the genetic factors per se influenced the therapeutic result or the psychiatric status at follow-up. A multiple epileptic or neurological predisposition affecting first degree relatives unfavourably influenced the prognosis regarding relief from seizures. A multiple psychiatric predisposition in parents and/or siblings unfavourably influenced the psychiatric status.

journal_name

Acta Neurol Scand

authors

Jensen I

doi

10.1111/j.1600-0404.1975.tb05833.x

subject

Has Abstract

pub_date

1975-11-01 00:00:00

pages

381-94

issue

5

eissn

0001-6314

issn

1600-0404

journal_volume

52

pub_type

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