Cerebral blood flow, cerebrovascular resistance and cerebral metabolic rate of oxygen in severe arterial hypoxia in dogs.

Abstract:

:Cerebral blood flow and cerebral oxygen uptake were studied during severe arterial hypoxia in anesthetized dogs. It was shown that the hypoxic vasodilatation in the brain reaches a limit at an arterial oxygen saturation at about 25% and that this vasodilatation is less than that which may be induced by hypercapnia. A further deepening of the arterial hypoxia at a maintained cerebral perfusion pressure is combined with a continuous decrease in cerebral venous oxygen tension and a reduced oxygen uptake.

journal_name

Acta Neurol Scand

authors

Ekström-Jodal B,Elfverson J,von Essen C

doi

10.1111/j.1600-0404.1979.tb02948.x

subject

Has Abstract

pub_date

1979-07-01 00:00:00

pages

26-35

issue

1

eissn

0001-6314

issn

1600-0404

journal_volume

60

pub_type

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