Is there a lamotrigine withdrawal syndrome?

abstract：OBJECTIVES:"Epileptic dementia" is reported in adults with childhood-onset refractory epilepsy. Cognitive deterioration can also occur in a "second-hit model". MATERIALS AND METHODS:We studied the clinical and neuropsychological characteristics of patients with cognitive deterioration (≥1 SD discrepancy between curren...

journal_title：Acta neurologica Scandinavica

authors： Breuer LEM,Grevers E,Boon P,Bernas A,Bergmans JWM,Besseling RMH,Klooster DCW,de Louw A,Mestrom RMC,Vonck K,Zinger S,Aldenkamp AP

更新日期：2017-07-01 00:00:00

abstract：:The genetic mutation underlying Huntington's disease (HD) has been identified as an expansion and instability of a specific CAG repeat sequence in a gene on chromosome 4. A simple polymerase chain reaction assay has been used for the assessment of the (CAG)n expansion in a 72-year-old woman with typical HD symptoms, b...

journal_title：Acta neurologica Scandinavica

authors： Bozza A,Malagù S,Calzolari E,Novelletto A,Pavoni M,del Senno L

更新日期：1995-08-01 00:00:00

abstract：:Serum and CSF from 53 vascular dementia (VD) patients and 50 controls were analysed to investigate the possibility of an intrathecal synthesis of IgG, defined as an elevated IgG index (greater than or equal to 7) and/or presence of oligoclonal IgG in cerebrospinal fluid (CSF), but not in serum. Five (9%) patients and ...

journal_title：Acta neurologica Scandinavica

authors： Wallin A,Blennow K,Fredman P,Gottfries CG,Karlsson I,Svennerholm L

更新日期：1990-02-01 00:00:00

abstract：:Three patients are described with muscular dystrophy and contractures. Although this disorder bears similarities to Emery-Dreifuss disease and variants previously described, absence of cardiomyopathy is a distinguishing feature. Electrodiagnostic testing and muscle biopsy are consistent with a myopathy. An autosomal d...

journal_title：Acta neurologica Scandinavica

authors： Bailey RO,Dentinger MP,Toms ME,Hans MB

更新日期：1986-04-01 00:00:00

abstract：:The authors tested the effects of 2-Br-ergocriptine (bromocriptine, CB-154), a drug which exerts a mixed agonist-antagonist activity on the dopaminergic receptors, in 12 patients with Huntington Chorea in a double-blind crossover trial. This treatment significantly reduced the abnormal involuntary movements and the di...

journal_title：Acta neurologica Scandinavica

authors： Frattola L,Albiazzati MG,Spano PF,Trabucchi M

更新日期：1977-07-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to investigate myopathic changes in myasthenia gravis (MG) by using turns-amplitude analysis (TAA) and quantitative motor unit potential duration analysis (MUPan), to correlate myopathic changes with severity and duration of the disease and the results of diagnostic tests includin...

journal_title：Acta neurologica Scandinavica

authors： Odabasi Z,Kuruoglu R,Oh SJ

更新日期：2000-05-01 00:00:00

abstract：:A case of transient global amnesia has been neuropsychologically assessed during the attack. Global involvement of any memory modalities and far-reaching retrograde amnesia were found. Follow-up retesting, 1 week and 6 months later, showed persistence of mild verbal memory impairment. ...

journal_title：Acta neurologica Scandinavica

authors： Caffarra P,Moretti G,Mazzucchi A,Parma M

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVES:To study the effects of different colour imaging modes on the contrast-medium-enhanced image of the intracranial cerebral arteries. METHODS:Twelve healthy volunteers were studied transcranially after administration of 10 ml BY963 successively with Power Doppler (p-TCCS) and with colour Doppler frequency ima...

journal_title：Acta neurologica Scandinavica

authors： Kaps M,Schaffer P,Beller KD,Seidel G,Wurst W

更新日期：1997-06-01 00:00:00

abstract：:The results of follow-up of 76 children with progressive ataxia first reported in 1988 are described with special reference to type of potential underlying metabolic diseases. In 70% of cases the clinical follow-up did not lead to reconsideration of diagnoses. Six of 23 biochemically and morphologically re-examined ch...

journal_title：Acta neurologica Scandinavica

authors： Ylitalo V,Hagberg BA

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:To clarify how chronic solvent abuse affects cognitive function using magnetic resonance imaging as an index of brain damage. MATERIAL AND METHODS:A total of 25 chronic solvent abusers underwent magnetic resonance imaging with quantitative neurometry and Wechsler Adult Intelligence Scales revised. RESULTS:T...

journal_title：Acta neurologica Scandinavica

authors： Yamanouchi N,Okada S,Kodama K,Sakamoto T,Sekine H,Hirai S,Murakami A,Komatsu N,Sato T

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVES:Mutations in the CHCHD10 gene, which encodes a mitochondrially targeted protein, have emerged as an important cause of motor neuron disease and frontotemporal lobar degeneration. The aim of this study was to assess the clinical variability in a large family carrying the p.Gly66Val mutation of the CHCHD10 gen...

journal_title：Acta neurologica Scandinavica

authors： Pasanen P,Myllykangas L,Pöyhönen M,Kiuru-Enari S,Tienari PJ,Laaksovirta H,Toppila J,Ylikallio E,Tyynismaa H,Auranen M

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:Biomarkers with the potential for longitudinal measurements are needed in multiple sclerosis (MS). Urine is easy to collect, and repeated sampling is possible. METHODS:39 paired CSF and urine samples were taken. Oligoclonal bands (OCBs) were measured in CSF. Kappa and lambda free light chain (FLC), neopteri...

journal_title：Acta neurologica Scandinavica

authors： Dobson R,Topping J,Davis A,Thompson E,Giovannoni G

更新日期：2013-11-01 00:00:00

abstract：:The prescriptions of antiepileptic drugs in the years 1985 and 1986 were used to identify all possible cases of epilepsy in a population of about 50,000 people. The general practitioners of the study area filled out a questionnaire for each user of antiepileptic drugs registered as a patient of theirs. This informatio...

journal_title：Acta neurologica Scandinavica

authors： Giuliani G,Terziani S,Senigaglia AR,Luccioni G,Foschi N,Maffei C

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:To measure clinical and immunological parameters in a patient with myasthenia gravis (MG) treated with antibodies against CD25 (basiliximab, Simulect). Patient and methods - Injections of basiliximab were given repeatedly together with cyclosporin A and corticosteroids for 9 months to a patient with severe M...

journal_title：Acta neurologica Scandinavica

authors： Kakoulidou M,Pirskanen-Matell R,Lefvert AK

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Excessive daytime sleepiness (EDS) is a symptom frequently presented in sleep clinics. Only a paucity of data has addressed clinical courses of sleep disorders with EDS. Therefore, we sought to compare clinical outcomes of patients presenting EDS. METHODS:A retrospective observational study was performed in...

journal_title：Acta neurologica Scandinavica

authors： Kim T,Lee JH,Lee CS,Yoon IY

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:Patients with Parkinson's disease (PD) and essential tremor (ET) have a higher risk of cognitive impairment than age-matched controls. Only a few small studies (11-18 subjects per group) have directly compared the cognitive profile of these conditions. Our aim was to compare the cognitive profile of patients...

journal_title：Acta neurologica Scandinavica

authors： Sánchez-Ferro Á,Benito-León J,Louis ED,Contador I,Hernández-Gallego J,Puertas-Martín V,Bermejo-Pareja F

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVES:We aimed to study knee proprioception and somatosensory evoked potentials (SEPs) to stimulation of the common peroneal nerve (CPN) in 7 patients with lesion of the anterior cruciate ligament (ACL) before and after ACL reconstruction. MATERIALS AND METHODS:We recorded the spinal N14 and scalp P27 potentials ...

journal_title：Acta neurologica Scandinavica

authors： Valeriani M,Restuccia D,Di Lazzaro V,Franceschi F,Fabbriciani C,Tonali P

更新日期：1999-05-01 00:00:00

abstract：:The objective of this paper is to evaluate the accuracy of conventional diagnostic criteria for Parkinson's disease and give an overview of alternative causes to parkinsonian syndromes. We also propose a new approach to the clinical diagnosis of Parkinson's disease, which may improve the diagnostic accuracy. The avail...

journal_title：Acta neurologica Scandinavica

authors： Larsen JP,Dupont E,Tandberg E

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVES:A highly adaptive aspect of human memory is the enhancement of explicit, consciously accessible memory by emotional stimuli. We studied the performance of Alzheimer's disease (AD) patients and elderly controls using a memory battery with emotional content, and we correlated these results with the amygdala an...

journal_title：Acta neurologica Scandinavica

authors： Schultz RR,de Castro CC,Bertolucci PH

更新日期：2009-08-01 00:00:00

abstract：:The effect of methylprednisolone (MP) on neurologic recovery and spinal cord blood flow (SCBF) was investigated up to 4 days after a spinal cord compression injury in rats. The injury was produced at midthoracic level by applying a load of 35 g on a 2.2 x 5.0 mm compression plate for 5 min, which resulted in transient...

journal_title：Acta neurologica Scandinavica

authors： Holtz A,Nyström B,Gerdin B

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVE:To prospectively detect significant transient F wave abnormalities obtained after exercise in patients with peripheral arterial disease (PAD) and to assess the potential diagnostic sensitivity of dynamic F wave study in such a context. PATIENTS AND METHODS:A series of 40 electrical stimuli were delivered to ...

journal_title：Acta neurologica Scandinavica

authors： Argyriou AA,Tsolakis I,Papadoulas S,Polychronopoulos P,Gourzis P,Chroni E

更新日期：2007-02-01 00:00:00

abstract：:The diagnosis of multiple sclerosis (MS) is clinical and verifiable at post mortem. Neuropathological examination of 518 consecutive patients with clinically definite MS revealed a correct diagnosis in 485 cases (94%). Clinical diagnosis had been established by a neurologist in all cases. Erroneous diagnosis included ...

journal_title：Acta neurologica Scandinavica

authors： Engell T

更新日期：1988-07-01 00:00:00

abstract：OBJECTIVES:Multiple sclerosis (MS) patients suffer from high levels of anxiety. However, it is unclear which factors are related to anxiety, since study results are inconsistent, and the associated factors have not been examined comprehensively. In this study, we investigated the demographic, disease-related and psycho...

journal_title：Acta neurologica Scandinavica

authors： Wallis O,Bol Y,Köhler S,van Heugten C

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:After surgery for ruptured anterior communicating artery (ACoA) aneurysm, several patients who have achieved a favorable neurological outcome yet have been observed to suffer from a poor cognitive outcome. The aim of this study was to explore the possible effects of temporary clip applications on frontal lob...

journal_title：Acta neurologica Scandinavica

authors： Akyuz M,Erylmaz M,Ozdemir C,Goksu E,Ucar T,Tuncer R

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:We examined whether the modulatory effect of pregnancy on multiple sclerosis (MS) is associated with changes in the apoptotic molecules in sera. SUBJECTS AND METHODS:The serum levels of tumor necrosis factor-related apoptosis-inducing ligand (sTRAIL), sFas, Fas ligand (sFasL) and macrophage migration inhibit...

journal_title：Acta neurologica Scandinavica

authors： Rinta S,Airas L,Elovaara I

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Pain is common in post-stroke patients and has been shown to be associated with depression, fatigue, and decreased quality of life (QOL). However, studies examining different types of post-stroke pain are scarce. We investigated differences in the related factors and their QOL impacts between mus...

journal_title：Acta neurologica Scandinavica

authors： Choi-Kwon S,Choi SH,Suh M,Choi S,Cho KH,Nah HW,Song H,Kim JS

更新日期：2017-04-01 00:00:00

abstract：:We report 20 cases of right unilateral spatial neglect caused by lesions in the left cerebral hemisphere. Differences in neuropsychological symptoms and lesions sites are discussed in connection with handedness. Of the right-handed patients, 6 had severe aphasia, 4 had Gerstmann's syndrome, and 1 had pure agraphia, bu...

journal_title：Acta neurologica Scandinavica

authors： Maeshima S,Shigeno K,Dohi N,Kajiwara T,Komai N

更新日期：1992-06-01 00:00:00

abstract：OBJECTIVES:To investigate the frequency of ECG abnormalities suggestive of myocardial ischaemia in patients with severe drug resistant epilepsy and without any indication of previous cardiac disease, assuming that these changes may be of significance for the group of epileptic patients with sudden unexpected death. MA...

journal_title：Acta neurologica Scandinavica

authors： Tigaran S,Rasmussen V,Dam M,Pedersen S,Høgenhaven H,Friberg B

更新日期：1997-08-01 00:00:00

abstract：:The urinary excretion of uronic acid and the electrophoretic composition of urinary glucosaminoglycans were studied in 10 members of a family, of which 3 had progressive familial myoclonus epilepsy. This seems to be the first detailed investigation of the excretion of urinary glucosaminoglycans in patients suffering f...

journal_title：Acta neurologica Scandinavica

authors： Poulsen JH

更新日期：1975-09-01 00:00:00

abstract：OBJECTIVES:Stroke is associated with a higher risk of occult cancer. We studied the types of occult cancer most often associated with stroke. MATERIALS AND METHODS:All patients with incident stroke in Denmark 2003-2015 were identified through the Danish Stroke Registry (n = 85 893) and matched 1:10 on age and sex to t...

journal_title：Acta neurologica Scandinavica

authors： Tybjerg AJ,Babore AD,Olsen TS,Andersen KK

更新日期：2020-11-01 00:00:00