Is the modulatory effect of pregnancy in multiple sclerosis associated with changes in blood apoptotic molecules?

abstract：:Twenty-one patients continued a double-blind crossover study to compare the prophylactic effect on migraine of propranolol and clonidine. The daily dosage of propranolol and clonidine was 160 mg and 100 microgram, respectively. Statistical analysis did not show any significant difference between the two drugs in respe...

journal_title：Acta neurologica Scandinavica

authors： Kåss B,Nestvold K

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:Variants in genes encoding enzymes involved in production, aggregation or degradation of beta-amyloid are potential risk factors for sporadic Alzheimer's disease (AD). METHODS:Meta-analyses on AD association with BACE1 exon 5, BACE1 intron 5, FE65 intron 13, CYP46 intron 2, alpha(1)-antichymotrypsine Ala17T...

journal_title：Acta neurologica Scandinavica

authors： Llorca J,Rodríguez-Rodríguez E,Dierssen-Sotos T,Delgado-Rodríguez M,Berciano J,Combarros O

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:To examine the factors that influence acute and total length of stay (LOS) for stroke patients. MATERIALS AND METHODS:The basis of this investigation was a population-based cohort of first-ever stroke patients (n = 388). Subjects were survivors of the initial hospitalization (n = 295). Age, sex, social fact...

journal_title：Acta neurologica Scandinavica

authors： Appelros P

更新日期：2007-07-01 00:00:00

abstract：:Three patients are described with muscular dystrophy and contractures. Although this disorder bears similarities to Emery-Dreifuss disease and variants previously described, absence of cardiomyopathy is a distinguishing feature. Electrodiagnostic testing and muscle biopsy are consistent with a myopathy. An autosomal d...

journal_title：Acta neurologica Scandinavica

authors： Bailey RO,Dentinger MP,Toms ME,Hans MB

更新日期：1986-04-01 00:00:00

abstract：:Stroke although rare in children, is an important cause of morbidity in the paediatric age group. Over a period of 8 years, 43 children (17 boys and 26 girls) in the age groups of 1-16 years (mean 8.02 yrs) presented with stroke which constituted 10% of all strokes in the young and 0.7% of all paediatric admissions. T...

journal_title：Acta neurologica Scandinavica

authors： Nagaraja D,Verma A,Taly AB,Kumar MV,Jayakumar PN

更新日期：1994-10-01 00:00:00

abstract：:A solid-phase radioimmunoassay was developed for the detection of glial fibrillary acidic protein (GFAP) and GFAP-specific immunoglobulin G (IgG) antibodies. In antibody assays purified GFAP was absorbed onto polystyrene beads, followed by incubation in dilutions of serum. (125-I)-labelled human anti-IgG was used to q...

journal_title：Acta neurologica Scandinavica

authors： Ruutiainen J,Newcombe J,Salmi A,Dahl D,Frey H

更新日期：1981-05-01 00:00:00

abstract：INTRODUCTION:Because of the limited information on cervical spondylotic radiculopathy, we conducted a door-to-door two-phase survey in a Sicilian municipality. MATERIAL AND METHODS:We first screened for cervical spondylotic radiculopathy among the inhabitants of the municipality: (N = 7653, as of the prevalence day, N...

journal_title：Acta neurologica Scandinavica

authors： Salemi G,Savettieri G,Meneghini F,Di Benedetto ME,Ragonese P,Morgante L,Reggio A,Patti F,Grigoletto F,Di Perri R

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVES:Hospital admission in otherwise healthy patients following a first unprovoked seizure is controversial. We aimed to evaluate the influence of admission in a neurology department on the identification of risk factors for seizure recurrence in patients with a first unprovoked seizure. MATERIALS AND METHODS:We...

journal_title：Acta neurologica Scandinavica

authors： Goldberg I,Neufeld MY,Auriel E,Gandelman-Marton R

更新日期：2013-07-01 00:00:00

abstract：:Twenty-seven patients with CT-scan-diagnosed arachnoid cysts in the middle cranial fossa were studied. Five (18%) presented with progressive symptoms related to raised intracranial pressure which had developed after minor trauma and secondary bleeding, 12 (44%) presented with non-progressive symptoms, and 10 (37%) exh...

journal_title：Acta neurologica Scandinavica

authors： Passero S,Filosomi G,Cioni R,Venturi C,Volpini B

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVES:To examine through a meta-analysis whether a treatment strategy of surgery plus the routine medical management saves lives and reduces disability in survivors of primary supratentorial intracerebral hematoma compared to routine medical management alone. MATERIAL AND METHODS:Computerized bibliographic search...

journal_title：Acta neurologica Scandinavica

authors： Prasad K,Browman G,Srivastava A,Menon G

更新日期：1997-02-01 00:00:00

abstract：:Patients with multiple sclerosis have an increased risk of infections compared to the general population. The increased risk has been described for decades and is not alone attributed to the use of disease-modifying drugs, but secondary to the disability. The introduction of more potent immunomodulatory drugs may caus...

journal_title：Acta neurologica Scandinavica

authors： Celius EG

更新日期：2017-11-01 00:00:00

abstract：:One cause of ischemic brain injury is free radical formation during recirculation. Allopurinol inhibits xanthine oxidase, an important source of free oxygen radicals. It is known that allopurinol pre-treatment has a protective action during cerebral ischemia. In the present study we exposed slices from the rat hippoca...

journal_title：Acta neurologica Scandinavica

authors： Hegstad E,Berg-Johnsen J,Langmoen IA

更新日期：1991-05-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine whether reactivation of Epstein-Barr (EBV) or activation of the anti-EBV immune response correlates with MS disease activity on MR imaging. METHODS:Subjects with early, active relapsing-remitting MS were studied for 16 weeks with blood and saliva samples collected...

journal_title：Acta neurologica Scandinavica

authors： Latham LB,Lee MJ,Lincoln JA,Ji N,Forsthuber TG,Lindsey JW

更新日期：2016-01-01 00:00:00

abstract：:There has been accumulation of the nutritional muscular dystrophy of the cattle in a certain western district of Finland where the prevalence of multiple sclerosis (MS) is also highest. This animal disease is due to lack of selenium (Se) and vitamin E. The Se content of whole blood was low (52.6 +/- 11.3 ng/ml) in MS ...

journal_title：Acta neurologica Scandinavica

authors： Wikström J,Westermarck T,Palo J

更新日期：1976-09-01 00:00:00

abstract：OBJECTIVES:To evaluate the long-term neuropsychological effects and magnetic resonance imaging (MRI) findings among retired patients with a history of exposure to carbon disulfide (CS2). MATERIAL AND METHODS:Seventy-four patients with a history of exposure to CS2 were divided into two equal groups according to their l...

journal_title：Acta neurologica Scandinavica

authors： Cho SK,Kim RH,Yim SH,Tak SW,Lee YK,Son MA

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVES:We describe 2 patients with epilepsy as an early manifestation of late onset metachromatic leukodystrophy (MLD). METHODS AND RESULTS:The first patient presented with epileptic seizures at the age of 34 years while neurological and cognitive abnormalities appeared later. MRI findings were compatible with leu...

journal_title：Acta neurologica Scandinavica

authors： Bostantjopoulou S,Katsarou Z,Michelakaki H,Kazis A

更新日期：2000-09-01 00:00:00

abstract：:The effects of bromocriptine in patients with Parkinson's disease manifesting various problems in levodopa therapy were tested in a double-blind manner with the collaboration of 59 institutions. The slow and low principle was in part adopted. Either bromocriptine or placebo was added to levodopa. Twenty-nine % of the ...

journal_title：Acta neurologica Scandinavica

authors： Toyokura Y,Mizuno Y,Kase M,Sobue I,Kuroiwa Y,Narabayashi H,Uono M,Nakanishi T,Kameyama M,Ito H

更新日期：1985-08-01 00:00:00

abstract：OBJECTIVES:Although leukoaraosis (LA) is a common CT findings, its pathogenesis remains debated: if small-artery pathology may explain in some cases white matter changes, many other factors, such as hemodynamic perturbations, might also lead to LA. To test these hypothesis, we determined the types of cerebrovascular ri...

journal_title：Acta neurologica Scandinavica

authors： Hénon H,Godefroy O,Lucas C,Pruvo JP,Leys D

更新日期：1996-08-01 00:00:00

abstract：:We present clinical and virological data on 9 patients, 7 women and 2 men aged 31-56 years, with recurrent aseptic meningitis (Mollaret's meningitis). Polymerase chain reaction detected Herpes simplex virus type 2 DNA in cerebrospinal fluid samples from all patients collected during their latest attacks of meningitis....

journal_title：Acta neurologica Scandinavica

authors： Jensenius M,Myrvang B,Størvold G,Bucher A,Hellum KB,Bruu AL

更新日期：1998-09-01 00:00:00

abstract：:The effect of the alpha-adrenergic blocking agent thymoxamine by intravenous administration was studied in 25 patients with spastic paraplegia and uninhibited neurogenic bladder. By cystometry a shift to the right of the first desire to void, the threshold of the first uninhibited contraction and a reduction of the pr...

journal_title：Acta neurologica Scandinavica

authors： Pedersen E,Tørring J,Klemar B

更新日期：1980-02-01 00:00:00

abstract：OBJECTIVE:There is a paucity of regional cerebral blood flow studies in Japanese encephalitis (JE). In this communication we report clinical, radiological and single photon emission computed tomography findings in subacute and chronic JE patients. MATERIAL AND METHODS:Eight JE patients whose ages ranged between 10 and...

journal_title：Acta neurologica Scandinavica

authors： Kalita J,Das BK,Misra UK

更新日期：1999-04-01 00:00:00

abstract：:In Sweden, the annual incidence of surgery for hydrocephalus was 3.4 per 100,000 adults between the years 1996 and 1998. The most common indication for surgery was normal pressure hydrocephalus (NPH; 47%), followed by high-pressure hydrocephalus (27%). Seventy-three percent of the patients had communicating hydrocepha...

journal_title：Acta neurologica Scandinavica

authors： Tisell M,Höglund M,Wikkelsø C

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVES:Strokes represent the most common etiology of epilepsy in patients over the age of 60 years, with an incidence of 2-4% occurring in different studies. MATERIALS AND METHODS:In this observational study, 1,428 patients were included who had stroke and were admitted to our Stroke Unit between the years 1996 an...

journal_title：Acta neurologica Scandinavica

authors： Benbir G,Ince B,Bozluolcay M

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:The Multiple Sclerosis Functional Composite (MSFC) is a multidimensional measurement tool for multiple sclerosis (MS) including a measure of ambulation (Timed 25-foot Walk [TWT]), arm function (Nine-Hole Peg Test [9HPT]) and cognition (Paced Auditory Serial Addition Test [PASAT]). OBJECTIVES:To assess the r...

journal_title：Acta neurologica Scandinavica

authors： Rosti-Otajärvi E,Hämäläinen P,Koivisto K,Hokkanen L

更新日期：2008-06-01 00:00:00

abstract：:The prevalence of probable multiple sclerosis (MS) in Caltanissetta city, Sicily, is at least 51 per 100,000. If possible multiple sclerosis patients are included, it is 54 per 100,000. This value is similar to that found in other cities in Sicily: Enna, Monreale and Agrigento. The high prevalence of multiple sclerosi...

journal_title：Acta neurologica Scandinavica

authors： Savettieri G,Elian M,Giordano D,Grimaldi G,Ventura A,Dean G

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVES:Myotonic dystrophy type 1 (DM1) is caused by large expansions of cytosine-thymine-guanine (CTG)-repeats in myotonic dystrophy protein kinase (DMPK)-gene. This gene is highly polymorphic in healthy individuals. It has been proposed that expanded alleles originated from the group of large sized normal alleles....

journal_title：Acta neurologica Scandinavica

authors： Culjković B,Stojković O,Vukosavić S,Savić D,Rakocevic V,Apostolski S,Romac S

更新日期：2002-01-01 00:00:00

abstract：:It has been suggested that nitric oxide could be implicated in the neuronal degeneration of substantia nigra compacta in patients with Parkinson's disease. Recently, it has been reported decreased CSF nitrate levels (oxidation product that provides an indirect estimation of nitric oxide) in Parkinson's disease patient...

journal_title：Acta neurologica Scandinavica

authors： Molina JA,Jiménez-Jiménez FJ,Navarro JA,Vargas C,Gómez P,Benito-León J,Ortí-Pareja M,Cisneros E,Arenas J

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:There has been a long-standing interest in the possible role of the hippocampus in autism and both postmortem brain and neuroimaging studies have documented varying abnormalities in this limbic system structure. AIMS:This study investigates the density of subsets of hippocampal interneurons, immunostained w...

journal_title：Acta neurologica Scandinavica

authors： Lawrence YA,Kemper TL,Bauman ML,Blatt GJ

更新日期：2010-02-01 00:00:00

abstract：:The spontaneous occurrence of blepharospasm and dystonic movements in face muscles, particularly those of the perioral and mandibular regions, has been named as Meige's disease which was first described by Henry Meige in 1910. We report the case of a woman with Meige's syndrome whose symptoms improved with the use of ...

journal_title：Acta neurologica Scandinavica

authors： Yardimci N,Karatas M,Kilinc M,Benli S

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVES:Alzheimer's disease assessment scale-cognitive subscale (ADAS-Cog) has become a standard clinical trials outcome for cognition, but has been recognized as deficient in areas including coverage of cognitive domains, sensitivity and standardization. Computerized test batteries may address some of these issues....

journal_title：Acta neurologica Scandinavica

authors： Wesnes K,Edgar C,Andreasen N,Annas P,Basun H,Lannfelt L,Zetterberg H,Blennow K,Minthon L

更新日期：2010-10-01 00:00:00