Computerized cognition assessment during acetylcholinesterase inhibitor treatment in Alzheimer's disease.

abstract：OBJECTIVES:Patients with Parkinson's disease (PD) and essential tremor (ET) have a higher risk of cognitive impairment than age-matched controls. Only a few small studies (11-18 subjects per group) have directly compared the cognitive profile of these conditions. Our aim was to compare the cognitive profile of patients...

journal_title：Acta neurologica Scandinavica

authors： Sánchez-Ferro Á,Benito-León J,Louis ED,Contador I,Hernández-Gallego J,Puertas-Martín V,Bermejo-Pareja F

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Guillain-Barre syndrome (GBS) is an acute disease of the peripheral nerves and their roots. Quality of life (QoL) in the first year after acute episode of GBS is still underresearched area. The aim of our study was to investigate QoL in GBS patients during a 6-month follow-up period. METHODS:Multicentric, pr...

journal_title：Acta neurologica Scandinavica

authors： Djordjevic G,Stojanov A,Bozovic I,Berisavac I,Arsenijevic M,Lukic Rajic S,Dominovic Kovacevic A,Jovanovic D,Basta I,Peric S

更新日期：2020-03-01 00:00:00

abstract：:By a rapid PCR-based method to assess the 8344 mtDNA mutation associated with MERRF disease, we have studied DNA from blood samples of 10 individuals belonging to a family spanning four generations in which one patient showed the complete MERRF phenotype, three other members were less severely affected, while the rema...

journal_title：Acta neurologica Scandinavica

authors： Piccolo G,Focher F,Verri A,Spadari S,Banfi P,Gerosa E,Mazzarello P

更新日期：1993-12-01 00:00:00

abstract：:Ten patients with pseudotumor cerebri were studied. The diagnosis was based on bilateral papilledema and absence of intracranial masses and hydrocephalus. Based on the radiological findings, three groups of patients emerged: (A) Five patients with an empty sella. Four had an enlarged sella; (B) Two patients with a pit...

journal_title：Acta neurologica Scandinavica

authors： Bjerre P,Lindholm J,Gyldensted C

更新日期：1982-10-01 00:00:00

abstract：:The influence of clonazepam on steady-state serum levels of diphenylhydantoin, phenobarbital and carbamazepine was studied in 22 patients with epilepsy receiving one or two of these drugs. Clonazepam was given in slowly increasing doses for 2 weeks until a maximum dose of 4-6 mg per day was reached; thereafter the dos...

journal_title：Acta neurologica Scandinavica

authors： Johannessen SI,Strandjord RE,Munthe-Kaas AW

更新日期：1977-06-01 00:00:00

abstract：:Thirty-eight demented patients were clinically investigated and classified into a multi-infarct dementia (MID) and senile dementia (SD) group. Total protein, albumin, immunoglobulin G, agar gel electrophoretic protein and iso-electric focusing pattern were determined in CSF and serum as well as the lactate dehydrogena...

journal_title：Acta neurologica Scandinavica

authors： Wikkelsø C,Blomstrand C,Nordquist P

更新日期：1981-07-01 00:00:00

abstract：:The intrathecal production (ITP) of the immunoglobulins (Ig) G, A, M and D was examined in untreated patients with multiple sclerosis (MS) and controls. Sensitive sandwich enzyme-linked immunosorbent assay systems were applied to the determination of IgA, IgM and IgD levels in the cerebrospinal fluid and plasma from a...

journal_title：Acta neurologica Scandinavica

authors： Lolli F,Halawa I,Link H

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Mild malformation of cortical dysplasia (mMCD) with oligodendroglial hyperplasia (MOGHE) is an epilepsy-related pathologic entity highlighted in post-surgical specimens of frontal lobe epilepsy (FLE) patients. AIMS OF THE STUDY:We present two temporal lobe epilepsy (TLE) cases with MOGHE and discuss clinica...

journal_title：Acta neurologica Scandinavica

authors： Garganis K,Kokkinos V,Zountsas B,Dinopoulos A,Coras R,Blümcke I

更新日期：2019-10-01 00:00:00

abstract：:Transitional progressive multiple sclerosis (MS) is quite an unusual form of presentation and course of the disease. A case with this progressive form is presented and brain MRI and MTI findings are discussed in relation to the possible insight they may provide for understanding the mechanisms that determine progressi...

journal_title：Acta neurologica Scandinavica

authors： Filippi M,Campi A,Martinelli V,Pereira C,Scotti G,Comi G

更新日期：1995-08-01 00:00:00

abstract：OBJECTIVES:Interindividual variability in intestinal absorption and bioavailability might contribute to inadequate control of seizures under treatment with carbamazepine and phenytoin. We therefore correlated intestinal expression levels and genetics of CYP3A4, CYP2C9/19, MDR1 and MRP2 with dose requirement and plasma ...

journal_title：Acta neurologica Scandinavica

authors： Simon C,Stieger B,Kullak-Ublick GA,Fried M,Mueller S,Fritschy JM,Wieser HG,Pauli-Magnus C

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVES:Therapy of acute relapses in multiple sclerosis with corticosteroids (CC) remains uncertain with respect to route, dosage and effectiveness. This makes the treatment of relapses a clinical field where 'shared decision-making (SDM)' could be of advantage for the patients. A prerequisite for SDM is the provisi...

journal_title：Acta neurologica Scandinavica

authors： Köpke S,Heesen C,Kasper J,Mühlhauser I

更新日期：2004-07-01 00:00:00

abstract：:The association of cortical tremor, myoclonus and epileptic seizures has been reported in many Japanese and European families with different acronyms. We reviewed the familial cases presenting the clinical picture of autosomal dominant cortical tremor, myoclonus and epilepsy and analysed the phenotypic differences bet...

journal_title：Acta neurologica Scandinavica

authors： Striano P,Zara F,Striano S

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:Individuals with Parkinson's disease (PD) and freezing of gait (FOG) present peripheral and central sensitivity disturbances that impair motor performance. This study aimed to investigate long-term effects of plantar sensory stimulation on brain activity, brain connectivity, and gait velocity of individuals w...

journal_title：Acta neurologica Scandinavica

authors： Pagnussat AS,Salazar AP,Pinto C,Redivo Marchese R,Rieder CRM,Alves Filho JO,Franco AR,Kleiner AFR

更新日期：2020-09-01 00:00:00

abstract：:Twenty-four consecutive patients with familial amyloidosis with polyneuropathy (type 1), who were at different stages of the disease were investigated. The purpose was to report the electrophysiological features and to compare them with those found in other generalized neuropathies; 12 cases were familiar and 12 cases...

journal_title：Acta neurologica Scandinavica

authors： Blom S,Steen L,Zetterlund B

更新日期：1981-02-01 00:00:00

abstract：:A young woman with firm evidence of early multiple sclerosis (MS), who had never had measles, developed a clinically and serologically evident measles infection. Follow-up 1 year later confirmed the MS diagnosis. Thus, if measles can have a causal role in MS, it is probably not the only agent with this ability. ...

journal_title：Acta neurologica Scandinavica

authors： Ryberg B

更新日期：1979-04-01 00:00:00

abstract：OBJECTIVES:To estimate dementia prevalence in Spain. MATERIALS AND METHODS:Nine probabilistic and geographically defined samples participated. A screening design based on the MMSE was implemented. Positively screened individuals underwent clinical evaluation. The total number of cases in Spain was estimated. Prevalenc...

journal_title：Acta neurologica Scandinavica

authors： Virués-Ortega J,de Pedro-Cuesta J,Vega S,Seijo-Martínez M,Saz P,Rodríguez F,Rodríguez-Laso A,Reñé R,de Las Heras SP,Mateos R,Martínez-Martín P,Mahillo-Fernández I,López-Pousa S,Lobo A,Reglà JL,Gascón J,García FJ,Fernánd

更新日期：2011-05-01 00:00:00

abstract：:The results of follow-up of 76 children with progressive ataxia first reported in 1988 are described with special reference to type of potential underlying metabolic diseases. In 70% of cases the clinical follow-up did not lead to reconsideration of diagnoses. Six of 23 biochemically and morphologically re-examined ch...

journal_title：Acta neurologica Scandinavica

authors： Ylitalo V,Hagberg BA

更新日期：1994-04-01 00:00:00

abstract：:Cerebral blood flow and cerebral oxygen uptake were studied during severe arterial hypoxia in anesthetized dogs. It was shown that the hypoxic vasodilatation in the brain reaches a limit at an arterial oxygen saturation at about 25% and that this vasodilatation is less than that which may be induced by hypercapnia. A ...

journal_title：Acta neurologica Scandinavica

authors： Ekström-Jodal B,Elfverson J,von Essen C

更新日期：1979-07-01 00:00:00

abstract：:The results of intra-operative cortical EEG recordings (ECoG) were assessed in 30 patients with medically refractory complex partial seizures submitted to temporal lobectomy. Interictal spiking was most frequently recorded from mesial temporal lobe structures (amygdaloid-hippocampal region) and from the temporal neoco...

journal_title：Acta neurologica Scandinavica

authors： Stefan H,Quesney LF,Abou-Khalil B,Olivier A

更新日期：1991-02-01 00:00:00

abstract：:A 54 year-old woman showed the unusual association of a Guillain-Barré syndrome and opsoclonus, a rare eye movement characterized by involuntary bursts of jerking, ataxic and multidirectional saccades, without an intersaccadic interval. Since opsoclonus is a phenomenon described exclusively in CNS diseases, the case r...

journal_title：Acta neurologica Scandinavica

authors： Nicolai A,Lazzarino LG

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVES:To estimate the need for and the costs of carotid Doppler and carotid endarterectomy after stroke or TIA in non-selected hospitalized patients. MATERIAL AND METHODS:During 25 months hospitalized patients with stroke or TIA, in whom carotid endarterectomy could be relevant, were examined with carotid Doppler...

journal_title：Acta neurologica Scandinavica

authors： Jespersen HF,Jørgensen HS,Nakayama H,Reith J,Olsen TS

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to investigate myopathic changes in myasthenia gravis (MG) by using turns-amplitude analysis (TAA) and quantitative motor unit potential duration analysis (MUPan), to correlate myopathic changes with severity and duration of the disease and the results of diagnostic tests includin...

journal_title：Acta neurologica Scandinavica

authors： Odabasi Z,Kuruoglu R,Oh SJ

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVE:Cognitive impairment occurs in 40%-65% of patients with multiple sclerosis (MS). Several techniques for cognitive rehabilitation (CR) in these patients have been evaluated; however, the results have been controversial. In this study, we investigated the efficacy of group compensatory CR in patients with MS-re...

journal_title：Acta neurologica Scandinavica

authors： Mani A,Chohedri E,Ravanfar P,Mowla A,Nikseresht A

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:The differential diagnosis of patients with idiopathic parkinsonism is difficult, especially early in the course of the disease. External anal sphincter electromyography (EAS-EMG) has been reported to be of value in the differential diagnosis between Parkinson's disease (PD) and multiple system atrophy (MSA)...

journal_title：Acta neurologica Scandinavica

authors： Linder J,Libelius R,Nordh E,Holmberg B,Stenlund H,Forsgren L

更新日期：2012-10-01 00:00:00

abstract：:The main metabolites of the neurotransmitters noradrenaline, dopamine, and serotonin, methoxy-hydroxyphenylglycol (MHPG), homovanillic acid (HVA), and 5-hydroxyindoleacetic acid (5HIAA) respectively, were estimated by HPLC with electrochemical detection in CSF samples from 24 patients in coma after head injury, 1 to 1...

journal_title：Acta neurologica Scandinavica

authors： Markianos M,Seretis A,Kotsou S,Baltas I,Sacharogiannis H

更新日期：1992-08-01 00:00:00

abstract：:We present a 47-year-old white woman who had a definitive diagnosis of systemic lupus erythematosus (SLE), and developed cerebellar ataxia of sudden onset. MR imaging showed changes characteristics of cerebellar infarct. Due to the absence of vascular risk factors and to the previous diagnosis of SLE, we postulate tha...

journal_title：Acta neurologica Scandinavica

authors： Lancman ME,Pomeraniec C,Norscini J

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVES:Although leukoaraosis (LA) is a common CT findings, its pathogenesis remains debated: if small-artery pathology may explain in some cases white matter changes, many other factors, such as hemodynamic perturbations, might also lead to LA. To test these hypothesis, we determined the types of cerebrovascular ri...

journal_title：Acta neurologica Scandinavica

authors： Hénon H,Godefroy O,Lucas C,Pruvo JP,Leys D

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVES:To assess the effectiveness and safety/tolerability of eslicarbazepine acetate (ESL) in patients included in the Euro-Esli study who had focal seizures associated with post-stroke epilepsy (PSE). MATERIALS AND METHODS:Euro-Esli was a pooled analysis of 14 European clinical practice studies. Effectiveness as...

journal_title：Acta neurologica Scandinavica

authors： Sales F,Chaves J,McMurray R,Loureiro R,Fernandes H,Villanueva V

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:We aimed to investigate associations between neuropsychological indices and normalized volumes of supratentorial structures, and the area of the corpus callosum. MATERIALS AND METHODS:We studied 40 patients with clinically definite MS, using 3D-acquired MRI (MPRAGE, Magnetization Prepared Rapid Acquisition ...

journal_title：Acta neurologica Scandinavica

authors： Edwards SG,Liu C,Blumhardt LD

更新日期：2001-10-01 00:00:00

abstract：:Using organotypic cultures of ICR mouse cerebellum, we studied the effects of TNF-alpha on myelin formation, and its demyelinating effects. Mature, myelinated cultures were resistant to TNF-alpha, even at the highest concentration examined, 1 x 10(4) U/ml. However, when cultures were grown in medium containing TNF-alp...

journal_title：Acta neurologica Scandinavica

authors： Tsukamoto T,Ishikawa M,Yamamoto T

更新日期：1995-01-01 00:00:00