Antivirus immune activity in multiple sclerosis correlates with MRI activity.

abstract：:The immediate effects of selective sympathetic and somatic blockades on pain and tactile allodynia in 12 patients with long-standing ophthalmic or high cervical postherpetic neuralgia were compared. For the duration of the somatic blockade, pain was completely abolished in 11 patients and allodynia in 8 patients. In c...

journal_title：Acta neurologica Scandinavica

authors： Nurmikko T,Wells C,Bowsher D

更新日期：1991-08-01 00:00:00

abstract：:Using organotypic cultures of ICR mouse cerebellum, we studied the effects of TNF-alpha on myelin formation, and its demyelinating effects. Mature, myelinated cultures were resistant to TNF-alpha, even at the highest concentration examined, 1 x 10(4) U/ml. However, when cultures were grown in medium containing TNF-alp...

journal_title：Acta neurologica Scandinavica

authors： Tsukamoto T,Ishikawa M,Yamamoto T

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a severe autoimmune disorder with a mortality of 5%-7%, but few studies have focused on the predictors of death in this disease. In this study, we aim to investigate predictors and causes of death in patients with anti-NMDAR encephalitis. METHODS:In ...

journal_title：Acta neurologica Scandinavica

authors： Chi X,Wang W,Huang C,Wu M,Zhang L,Li J,Zhou D

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVES:Spinocerebellar ataxia type 7 is a rare autosomal dominant neurodegenerative disorder characterized by progressive cerebellar and retinal degeneration, described in various population groups in the literature. This is the first description from South Africa. The objective was to document the clinical and gen...

journal_title：Acta neurologica Scandinavica

authors： Modi G,Modi M,Martinus I,Rodda J,Saffer D

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVES:A highly adaptive aspect of human memory is the enhancement of explicit, consciously accessible memory by emotional stimuli. We studied the performance of Alzheimer's disease (AD) patients and elderly controls using a memory battery with emotional content, and we correlated these results with the amygdala an...

journal_title：Acta neurologica Scandinavica

authors： Schultz RR,de Castro CC,Bertolucci PH

更新日期：2009-08-01 00:00:00

abstract：:Patients with aseptic meningitis (AM) were examined with the active T cell rosette test, which has been claimed to reflect cell-mediated immunocompetence more accurately than determination of total T cells. Higher percentages of active T cells were demonstrated in CSF compared to blood regardless if specimens were obt...

journal_title：Acta neurologica Scandinavica

authors： Frydén A,Kam-Hansen S,Maller R,Link H

更新日期：1980-05-01 00:00:00

abstract：OBJECTIVES:To investigate efficacy and safety of entacapone across phase III studies in Parkinson's disease (PD) with wearing-off symptoms. METHODS:Retrospective, pooled analysis of four phase 3 randomized, double-blind, placebo-controlled studies with entacapone. RESULTS:475 of 808 patients with PD received entacapo...

journal_title：Acta neurologica Scandinavica

authors： Kuoppamäki M,Vahteristo M,Ellmén J,Kieburtz K

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVES:To examine the factors that influence acute and total length of stay (LOS) for stroke patients. MATERIALS AND METHODS:The basis of this investigation was a population-based cohort of first-ever stroke patients (n = 388). Subjects were survivors of the initial hospitalization (n = 295). Age, sex, social fact...

journal_title：Acta neurologica Scandinavica

authors： Appelros P

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune disorder of the central nervous system (CNS). Interleukin (IL)-6 and IL-17A may play important roles in the pathogenesis of this disease. High-mobility group box protein 1 (HMGB1), a small but highly conserved ubiquitous protein, is rec...

journal_title：Acta neurologica Scandinavica

authors： Ai P,Zhang X,Xie Z,Liu G,Liu X,Pan S,Wang H

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:To describe the influence of the site of the bleeding on clinical spectrum and early outcome of patients with acute spontaneous intracerebral hemorrhage (ICH). MATERIALS AND METHODS:ICH was diagnosed in 229 (11%) of 2000 consecutive stroke patients included in a prospective stroke registry over a 10-year pe...

journal_title：Acta neurologica Scandinavica

authors： Arboix A,Comes E,García-Eroles L,Massons J,Oliveres M,Balcells M,Targa C

更新日期：2002-04-01 00:00:00

abstract：:Further studies pm yjr rofr,op;phu pg ,i;yo;r dv;rtpdod (MS) IN Finland were carried out in three different types of geographical unit: in counties, combined clerical districts, and single clerical district. For longitudinal studies, the prevalence of MS by present domicile was compared to that by place of birth, and ...

journal_title：Acta neurologica Scandinavica

authors： Wikström J,Palo J

更新日期：1975-02-01 00:00:00

abstract：:The influence on the cystometrogram of repeated filling and varying filling rates was studied in two groups of neurological patients, one with normal and one with uninhibited neurogenic bladder. A technique which permits an even bladder filling and a continuous recording of the intravesical pressure was used. The effe...

journal_title：Acta neurologica Scandinavica

authors： Jensen D Jr

更新日期：1981-09-01 00:00:00

abstract：:Both carotid endarterectomy (CEA) and carotid artery stenting (CAS) are common treatments for carotid artery stenosis. Several randomized controlled trials (RCTs) have compared CEA to CAS in the treatment of carotid artery stenosis. These studies have suggested that CAS is more strongly associated with periprocedural ...

journal_title：Acta neurologica Scandinavica

authors： Lamanna A,Maingard J,Barras CD,Kok HK,Handelman G,Chandra RV,Thijs V,Brooks DM,Asadi H

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:We examined whether the modulatory effect of pregnancy on multiple sclerosis (MS) is associated with changes in the apoptotic molecules in sera. SUBJECTS AND METHODS:The serum levels of tumor necrosis factor-related apoptosis-inducing ligand (sTRAIL), sFas, Fas ligand (sFasL) and macrophage migration inhibit...

journal_title：Acta neurologica Scandinavica

authors： Rinta S,Airas L,Elovaara I

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVES:Interindividual variability in intestinal absorption and bioavailability might contribute to inadequate control of seizures under treatment with carbamazepine and phenytoin. We therefore correlated intestinal expression levels and genetics of CYP3A4, CYP2C9/19, MDR1 and MRP2 with dose requirement and plasma ...

journal_title：Acta neurologica Scandinavica

authors： Simon C,Stieger B,Kullak-Ublick GA,Fried M,Mueller S,Fritschy JM,Wieser HG,Pauli-Magnus C

更新日期：2007-04-01 00:00:00

abstract：:Twenty-seven patients with CT-scan-diagnosed arachnoid cysts in the middle cranial fossa were studied. Five (18%) presented with progressive symptoms related to raised intracranial pressure which had developed after minor trauma and secondary bleeding, 12 (44%) presented with non-progressive symptoms, and 10 (37%) exh...

journal_title：Acta neurologica Scandinavica

authors： Passero S,Filosomi G,Cioni R,Venturi C,Volpini B

更新日期：1990-08-01 00:00:00

abstract：:X-linked adrenoleukodystrophy/adrenomyeloneuropathy presents a wide variation of clinical manifestations and may mimic several diseases. A screening investigation by measuring plasma saturated very long-chain fatty acids was performed in two groups of patients. Among six patients with hereditary spastic paraparesis on...

journal_title：Acta neurologica Scandinavica

authors： Holmberg BH,Hägg E,Duchek M,Hagenfeldt L

更新日期：1992-02-01 00:00:00

abstract：:The diagnosis of multiple sclerosis (MS) is clinical and verifiable at post mortem. Neuropathological examination of 518 consecutive patients with clinically definite MS revealed a correct diagnosis in 485 cases (94%). Clinical diagnosis had been established by a neurologist in all cases. Erroneous diagnosis included ...

journal_title：Acta neurologica Scandinavica

authors： Engell T

更新日期：1988-07-01 00:00:00

abstract：:The data for 125 patients with Spielmeyer-Sjögren's disease is presented. Antioxidant therapy was given to 49. 27 received a combination of vitamin E, vitamin C, methionine and BHT. As the disease began to progress, the treatment was changed to a combination of sodium selenite and vitamin E in 14 of the 27 patients. T...

journal_title：Acta neurologica Scandinavica

authors： Santavuori P,Westermarck T,Rapola J,Pohja P,Moren R,Lappi M,Vuonnala U

更新日期：1985-02-01 00:00:00

abstract：OBJECTIVES:It was shown previously that low-Mg2+-induced epileptiform activity in rat entorhinal cortex slices changes with time from a pattern of serial seizure-like events (SLEs) to a state of continuously recurring epileptiform activity. Valproic acid blocked the early SLEs but not the late activity. It was proposed...

journal_title：Acta neurologica Scandinavica

authors： Dreier JP,Zhang CL,Heinemann U

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVES:Clinical research has documented a range of evidence-based treatment approaches for spatial neglect (SN), but there is a lack of research on the implementation of treatment into clinical practice. The purpose of this study is to describe the current clinical practice of SN treatment across healthcare sectors...

journal_title：Acta neurologica Scandinavica

authors： Evald L,Wilms IL,Nordfang M

更新日期：2020-01-01 00:00:00

abstract：:Variants in the EIF4G1 gene have been recently identified to be responsible for autosomal dominant PD (PARK18), but its role in the PD-related neurodegeneration is unclear. Several EIF4G1 mutation/variants were found to be associated with PD, and functional studies have suggested that these variants may impair the abi...

journal_title：Acta neurologica Scandinavica

authors： Deng H,Wu Y,Jankovic J

更新日期：2015-08-01 00:00:00

abstract：:The cerebrovascular response to arterial hypoxia was studied during blockade of the vascular dopamine receptors and during alpha-adrenergic receptor stimulation and blockade in anaesthetized dogs. Dopamine receptor blockade with pimozide or haloperidol invariably decreased the degree of hypoxic vasodilatation in the ...

journal_title：Acta neurologica Scandinavica

authors： Ekström-Jodal B,Elfverson J,von Essen C

更新日期：1978-02-01 00:00:00

abstract：OBJECTIVES:Mutations in the CHCHD10 gene, which encodes a mitochondrially targeted protein, have emerged as an important cause of motor neuron disease and frontotemporal lobar degeneration. The aim of this study was to assess the clinical variability in a large family carrying the p.Gly66Val mutation of the CHCHD10 gen...

journal_title：Acta neurologica Scandinavica

authors： Pasanen P,Myllykangas L,Pöyhönen M,Kiuru-Enari S,Tienari PJ,Laaksovirta H,Toppila J,Ylikallio E,Tyynismaa H,Auranen M

更新日期：2016-05-01 00:00:00

abstract：:Genetic investigation of 74 patients with temporal lobe epilepsy, resistant to medication, who underwent unilateral temporal lobectomy 1960-1969. Thirty per cent had a positive family history of epilepsy; 49 per cent of other neurological diseases; and 46 per cent of major psychiatric disorders. Neither of the genetic...

journal_title：Acta neurologica Scandinavica

authors： Jensen I

更新日期：1975-11-01 00:00:00

abstract：:Anti-muscle-specific receptor tyrosine kinase (MuSK) antibody-positive myasthenia gravis (MG) patients show various responses to conventional immunosuppressive treatment and some patients are resistant to these therapies. We report a 50-year-old Japanese man with anti-MuSK antibody-positive MG, who showed no or poor r...

journal_title：Acta neurologica Scandinavica

authors： Shibata-Hamaguchi A,Samuraki M,Furui E,Iwasa K,Yoshikawa H,Hayashi S,Yamada M

更新日期：2007-12-01 00:00:00

abstract：:The genetic mutation underlying Huntington's disease (HD) has been identified as an expansion and instability of a specific CAG repeat sequence in a gene on chromosome 4. A simple polymerase chain reaction assay has been used for the assessment of the (CAG)n expansion in a 72-year-old woman with typical HD symptoms, b...

journal_title：Acta neurologica Scandinavica

authors： Bozza A,Malagù S,Calzolari E,Novelletto A,Pavoni M,del Senno L

更新日期：1995-08-01 00:00:00

abstract：:3-methoxy-4-hydroxyphenylglycol (MHPG) and 5-hydroxyindoleacetic acid (5-HIAA) as well as homovanillic acid (HVA) and cyclic AMP were estimated in the morning urine of 41 drug-free parkinsonian patients and 25 hospitalized controls. In 29 patients, the estimations were repeated after 2 weeks treatment with L-dopa plus...

journal_title：Acta neurologica Scandinavica

authors： Markianos M,Hadjikonstantinou M,Bistolaki E

更新日期：1982-08-01 00:00:00

abstract：OBJECTIVES:Increased aqueduct cerebrospinal fluid (CSF) flow pulsatility and, recently, a reversed CSF flow in the aqueduct have been suggested as hallmarks of idiopathic normal pressure hydrocephalus (INPH). However, these findings have not been adequately confirmed. Our objective was to investigate the flow of blood ...

journal_title：Acta neurologica Scandinavica

authors： Qvarlander S,Ambarki K,Wåhlin A,Jacobsson J,Birgander R,Malm J,Eklund A

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Persons with multiple sclerosis (MS) engage in substantially less overall physical activity than healthy controls, but there is little information on public health rates of physical activity necessary for health benefits. PURPOSE:This study examined the rates of insufficient, moderate, and sufficient physic...

journal_title：Acta neurologica Scandinavica

authors： Motl RW,McAuley E,Sandroff BM,Hubbard EA

更新日期：2015-06-01 00:00:00