Studies on the influence of monoamines on the cerebrovascular response to arterial hypoxia.

abstract：BACKGROUND:Previous studies have shown that status epilepticus can lead to neuronal injury. However, the effect of a small number of isolated seizures is uncertain. METHODS:We used structural MRI and neuropathology to study the effects of isolated seizures induced by kainic acid (KA), (RS)-2-amino-3-(3-hydroxy-5-tert-...

journal_title：Acta neurologica Scandinavica

authors： Acosta MT,Munashinge J,Zhang L,Guerron DA,Vortmeyer A,Theodore WH

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:Parkinson's disease (PD) may be associated with increased energy metabolism in overactive regions of the basal ganglia. Therefore, we hypothesized that treatment with the N-methyl-d-aspartate receptor (NMDAR) antagonist memantine would decrease regional cerebral blood flow (rCBF) and oxygen metabolism in the...

journal_title：Acta neurologica Scandinavica

authors： Borghammer P,Vafaee M,Ostergaard K,Rodell A,Bailey C,Cumming P

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:Cognitive impairment occurs in 40%-65% of patients with multiple sclerosis (MS). Several techniques for cognitive rehabilitation (CR) in these patients have been evaluated; however, the results have been controversial. In this study, we investigated the efficacy of group compensatory CR in patients with MS-re...

journal_title：Acta neurologica Scandinavica

authors： Mani A,Chohedri E,Ravanfar P,Mowla A,Nikseresht A

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:To evaluate the presence of the afterdischarge activity following M- and F-waves in patients with peripheral neuropathies with or without muscle cramps. MATERIAL AND METHODS:Ten patients with peripheral neuropathies complaining of frequent muscle leg cramps (Group 1) and 14 patients with peripheral neuropat...

journal_title：Acta neurologica Scandinavica

authors： Parisi L,Serrao M,Rossi P,Valente G,Fattapposta F,Pierelli F,Amabile G

更新日期：2000-12-01 00:00:00

abstract：:Ten patients with pseudotumor cerebri were studied. The diagnosis was based on bilateral papilledema and absence of intracranial masses and hydrocephalus. Based on the radiological findings, three groups of patients emerged: (A) Five patients with an empty sella. Four had an enlarged sella; (B) Two patients with a pit...

journal_title：Acta neurologica Scandinavica

authors： Bjerre P,Lindholm J,Gyldensted C

更新日期：1982-10-01 00:00:00

abstract：:The dibenzazepines particularly carbamazepine are associated with known adverse effects (AEs) and drug to drug interactions. Eslicarbazepine acetate (ESL) is structurally distinct from other members of the dibenzazepine family and has the advantage of once daily dosing. Observational and trial data report successful s...

journal_title：Acta neurologica Scandinavica

authors： Watkins L,O'Dwyer M,Oak K,Lawthom C,Maguire M,Thomas R,Shankar R

更新日期：2020-08-01 00:00:00

abstract：:Cerebral blood flow and cerebral oxygen uptake were studied during severe arterial hypoxia in anesthetized dogs. It was shown that the hypoxic vasodilatation in the brain reaches a limit at an arterial oxygen saturation at about 25% and that this vasodilatation is less than that which may be induced by hypercapnia. A ...

journal_title：Acta neurologica Scandinavica

authors： Ekström-Jodal B,Elfverson J,von Essen C

更新日期：1979-07-01 00:00:00

abstract：OBJECTIVES:In this follow-up study, we wanted to present the long-term outcome (5-21 years) in terms of seizure freedom, seizure reduction, and the cognitive development in the first 47 children who underwent epilepsy surgery at the University Hospital in Lund from 1991 to 2007. MATERIALS AND METHODS:All children who ...

journal_title：Acta neurologica Scandinavica

authors： Hallböök T,Tideman P,Rosén I,Lundgren J,Tideman E

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVES:We studied the in vitro production of variably MS-related cytokines from Sardinian MS and healthy donors bearing the two "Sardinian" MS-associated HLA-DR alleles: DR3 and DR4, with the purpose to evidentiate possible differences in their immune response. MATERIALS AND METHODS:ELISA were used for detection o...

journal_title：Acta neurologica Scandinavica

authors： Sotgiu S,Serra C,Marrosu MG,Dolei A,Pugliatti M,Murgia B,Aiello I,Rosati G

更新日期：1998-11-01 00:00:00

abstract：:The data for 125 patients with Spielmeyer-Sjögren's disease is presented. Antioxidant therapy was given to 49. 27 received a combination of vitamin E, vitamin C, methionine and BHT. As the disease began to progress, the treatment was changed to a combination of sodium selenite and vitamin E in 14 of the 27 patients. T...

journal_title：Acta neurologica Scandinavica

authors： Santavuori P,Westermarck T,Rapola J,Pohja P,Moren R,Lappi M,Vuonnala U

更新日期：1985-02-01 00:00:00

abstract：:A microtechnique was established for the study of the limited numbers of cells available in CSF. The method allowed for the determination of the number of immunoglobulin-secreting cells (IgSC) as well as the quantitation of immunoglobulin or specific antibody secreted into the culture medium. Dose-response curves and ...

journal_title：Acta neurologica Scandinavica

authors： Sandberg M,Levinson AI,Zweiman B,Lisak RP

更新日期：1986-12-01 00:00:00

abstract：:Regional blood flow in the spinal cord was measured in rabbits, cats and monkeys with radioactively labelled microspheres. The reproducibility of the method was tested in rabbits by 3 consecutive determinations with differently labelled microspheres within the different cord regions, and was found to be good. In all 3...

journal_title：Acta neurologica Scandinavica

authors： Nyström B,Stjernschantz J,Smedegård G

更新日期：1984-10-01 00:00:00

abstract：:Cerebral blood flow (CBF) was studied in 4 patients with acute reversible ischemia (RIND). To test the ischemic areas' vasoreactivity, CBF was measured by the Xenon-133 inhalation method, before and after acetazolamide injected intravenously. At the baseline CBF study, 3 patients presented hypoperfused areas while one...

journal_title：Acta neurologica Scandinavica

authors： Di Piero V,Pozzilli C,Pantano P,Grasso MG,Fieschi C

更新日期：1989-07-01 00:00:00

abstract：:Anti-muscle-specific receptor tyrosine kinase (MuSK) antibody-positive myasthenia gravis (MG) patients show various responses to conventional immunosuppressive treatment and some patients are resistant to these therapies. We report a 50-year-old Japanese man with anti-MuSK antibody-positive MG, who showed no or poor r...

journal_title：Acta neurologica Scandinavica

authors： Shibata-Hamaguchi A,Samuraki M,Furui E,Iwasa K,Yoshikawa H,Hayashi S,Yamada M

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:Machado-Joseph disease (MJD)/spinocerebellar ataxia type 3 is an autosomal dominant spinocerebellar degeneration, for which there is no effective treatment. PATIENTS AND METHODS:This study involved the clinical response of lamotrigine (LTG) on six MJD patients with early truncal ataxia and the effect of LTG ...

journal_title：Acta neurologica Scandinavica

authors： Liu CS,Hsu HM,Cheng WL,Hsieh M

更新日期：2005-06-01 00:00:00

abstract：:Psychometric tests, visual reaction time tests and electroencephalograms were performed in 26 cirrhotic patients without overt portal-systemic encephalopathy and in 26 healthy individuals. Cirrhotics performed poorly, compared with controls, on intelligence, learning and memory, perceptual motor and spatial tests. Non...

journal_title：Acta neurologica Scandinavica

authors： Puca FM,Antonaci F,Panella C,Guglielmi FW,Barone M,Francavilla A,Cerutti R

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVES:The objective was to investigate the incidence of multiple sclerosis (MS) as well as estimate the prevalence as of 1 January 2014 in the southeastern Norwegian county of Buskerud. MATERIALS AND METHODS:All patients with MS living in Buskerud county in Norway between 01 January 2003 and 01 January 2014 were ...

journal_title：Acta neurologica Scandinavica

authors： Simonsen CS,Edland A,Berg-Hansen P,Celius EG

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVES:To investigate the association between tumor necrosis factor-alpha (TNF-alpha) G-308A, tumor necrosis factor-beta (TNF-beta) G+252A and interleukin-4 (IL-4) C-590T polymorphisms and susceptibility to multiple sclerosis (MS) development and clinical course of the disease. MATERIALS AND METHODS:Two hundred an...

journal_title：Acta neurologica Scandinavica

authors： Kamali-Sarvestani E,Nikseresht A,Aflaki E,Sarvari J,Gharesi-Fard B

更新日期：2007-03-01 00:00:00

abstract：:This study is a report of 34 cases of Guillain-Barré syndrome (GBS) observed in Bangalore (South India), an endemic area for Japanese encephalitis virus (JEV) infection. Virological and immunological findings suggested an antecedent and recent JEV infection in 21/34 patients. Nineteen patients among them showed high l...

journal_title：Acta neurologica Scandinavica

authors： Ravi V,Taly AB,Shankar SK,Shenoy PK,Desai A,Nagaraja D,Gourie-Devi M,Chandramuki A

更新日期：1994-07-01 00:00:00

abstract：:The aim of this study was to ascertain whether there is an association between risk of multiple sclerosis (MS) and birth order position. Our reference population was 198,000 persons born in the period 1930-50 and recorded in the register of school health records from the school health service of the Copenhagen council...

journal_title：Acta neurologica Scandinavica

authors： Isager H,Andersen E,Hyllested K

更新日期：1980-06-01 00:00:00

abstract：OBJECTIVES:To estimate the need for and the costs of carotid Doppler and carotid endarterectomy after stroke or TIA in non-selected hospitalized patients. MATERIAL AND METHODS:During 25 months hospitalized patients with stroke or TIA, in whom carotid endarterectomy could be relevant, were examined with carotid Doppler...

journal_title：Acta neurologica Scandinavica

authors： Jespersen HF,Jørgensen HS,Nakayama H,Reith J,Olsen TS

更新日期：2002-01-01 00:00:00

abstract：:We studied clinically and electrophysiologically 8 patients affected by orthostatic tremor (OT), which is an unusual movement disorder consisting of shaking movements of the legs and trunk in the standing position. We failed to find any cause in 6 of the 8 cases. In 2 patients OT was clearly secondary to neurologic di...

journal_title：Acta neurologica Scandinavica

authors： Gabellini AS,Martinelli P,Gullì MR,Ambrosetto G,Ciucci G,Lugaresi E

更新日期：1990-02-01 00:00:00

abstract：:The possibility of disturbed dopamine and serotonin metabolism in senile dementia of Alzheimer type was studied. The basal concentrations of homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) in cerebrospinal fluid (CSF) were studied in 28 patients with senile dementia of Alzheimer type and in 13 controls...

journal_title：Acta neurologica Scandinavica

authors： Soininen H,MacDonald E,Rekonen M,Riekkinen PJ

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Neuropsychiatric symptoms are common in Parkinson's disease and may precede onset of motor symptoms. They are also known to increase caregiver's burden. OBJECTIVE:The aim of this study was to assess neuropsychiatric symptoms in a cohort of Nigerian patients with idiopathic Parkinson's disease and compare wi...

journal_title：Acta neurologica Scandinavica

authors： Ojagbemi AA,Akinyemi RO,Baiyewu O

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:Little is known about the frequency of abnormal visually evoked potentials (VEPs) in patients with respiratory chain disorders (RCDs). We thus wanted to investigate the frequency of abnormal VEPs in RCDs, how often VEPs are abnormal despite normal visual acuity, and which of the VEP variables are most often ...

journal_title：Acta neurologica Scandinavica

authors： Finsterer J

更新日期：2001-07-01 00:00:00

abstract：:To clarify the central nervous and the cardiovascular mechanisms mediating the Cushing response (CR) during intracranial hypertension, the effects of continuous and prolonged expansion of an epidural supratentorial balloon was studied in six dogs. Regional cerebral blood flow, cardiac output, extracerebral tissue bloo...

journal_title：Acta neurologica Scandinavica

authors： Schrader H,Hall C,Zwetnow NN

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVES:To determine headache characteristics in the obstructive sleep apnea syndrome (OSAS) and in insomnia. PATIENTS AND METHODS:Fifty-six OSAS patients and 50 insomnia patients were assessed in the same time period. Patients in both groups underwent an accurate interview to investigate headache occurrence and it...

journal_title：Acta neurologica Scandinavica

authors： Alberti A,Mazzotta G,Gallinella E,Sarchielli P

更新日期：2005-05-01 00:00:00

abstract：:Using organotypic cultures of ICR mouse cerebellum, we studied the effects of TNF-alpha on myelin formation, and its demyelinating effects. Mature, myelinated cultures were resistant to TNF-alpha, even at the highest concentration examined, 1 x 10(4) U/ml. However, when cultures were grown in medium containing TNF-alp...

journal_title：Acta neurologica Scandinavica

authors： Tsukamoto T,Ishikawa M,Yamamoto T

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVES:Until now, the significance of plasma exchange (PE) as a treatment for steroid-unresponsive optic neuritis (ON) is still unclear because placebo-controlled and larger studies are missing. We report our experience with 23 patients treated by PE due to steroid-unresponsive ON. MATERIALS AND METHODS:Patients w...

journal_title：Acta neurologica Scandinavica

authors： Roesner S,Appel R,Gbadamosi J,Martin R,Heesen C

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:It has been suggested that polymorphisms in the WT1 gene modulate the effect of IFN-β treatment in multiple sclerosis (MS) through regulation of the relationship between IFN-β and vitamin D. OBJECTIVE:To examine whether WT1 modulates the relationship between IFN-β and vitamin D in a longitudinal study with ...

journal_title：Acta neurologica Scandinavica

authors： Holmøy T,Esbensen QY,Torkildsen Ø,Wergeland S,Bjerve KS,Beiske AG,Midgard R,Šaltytė-Benth J,Hovdal H,Myhr KM

更新日期：2016-04-01 00:00:00