Abstract:
:Regional blood flow in the spinal cord was measured in rabbits, cats and monkeys with radioactively labelled microspheres. The reproducibility of the method was tested in rabbits by 3 consecutive determinations with differently labelled microspheres within the different cord regions, and was found to be good. In all 3 species, the blood flow was higher in the lumbar part of the cord than in the thoracic part, and in rabbits and monkeys it was also higher in the cervical than in the thoracic part. The flow values for the cervical, lower thoracic and lumbar parts of the cord in rabbits were 33.3, 24.7, and 27.3 ml X min-1 X 100 g-1, respectively, and in monkeys the respective figures were 14.9, 10.5 and 19.7 ml X min-1 X 100 g-1. Corresponding values for cats were only obtained during moderate hyperventilation, and were 12.2, 10.6, and 15.4 ml X min-1 X 100 g-1, respectively. The results are in good accordance with those of previous studies of the blood flow in the spinal cord in which other techniques have been employed.
journal_name
Acta Neurol Scandjournal_title
Acta neurologica Scandinavicaauthors
Nyström B,Stjernschantz J,Smedegård Gdoi
10.1111/j.1600-0404.1984.tb00828.xsubject
Has Abstractpub_date
1984-10-01 00:00:00pages
307-13issue
4eissn
0001-6314issn
1600-0404journal_volume
70pub_type
杂志文章abstract::The cerebrovascular response to arterial hypoxia was studied during blockade of the vascular dopamine receptors and during alpha-adrenergic receptor stimulation and blockade in anaesthetized dogs. Dopamine receptor blockade with pimozide or haloperidol invariably decreased the degree of hypoxic vasodilatation in the ...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1978.tb02833.x
更新日期:1978-02-01 00:00:00
abstract:OBJECTIVE:To compare the sensitivity and specificity of isoelectric focusing (IEF) with immunofixation, agarose gel electrophoresis (AGE) and the IgG index in detecting intrathecally synthesized IgG in multiple sclerosis (MS) and in other nervous system disorders. MATERIALS AND METHODS:Cerebrospinal fluid (CSF) and se...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0404.2000.102005322.x
更新日期:2000-11-01 00:00:00
abstract::The possible association of 7 HLA specificities in the HLA-A locus and 16 specificities in the HLA-B locus with susceptibility to Parkinsonian syndrome was investigated in a total of 36 patients with paralysis agitans (PA), as well as in 11 patients with other Parkinsonian syndromes, and 176 controls in Japan. There w...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1982.tb03147.x
更新日期:1982-11-01 00:00:00
abstract::We studied clinically and electrophysiologically 8 patients affected by orthostatic tremor (OT), which is an unusual movement disorder consisting of shaking movements of the legs and trunk in the standing position. We failed to find any cause in 6 of the 8 cases. In 2 patients OT was clearly secondary to neurologic di...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1990.tb00944.x
更新日期:1990-02-01 00:00:00
abstract::The genetic mutation underlying Huntington's disease (HD) has been identified as an expansion and instability of a specific CAG repeat sequence in a gene on chromosome 4. A simple polymerase chain reaction assay has been used for the assessment of the (CAG)n expansion in a 72-year-old woman with typical HD symptoms, b...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1995.tb01026.x
更新日期:1995-08-01 00:00:00
abstract::Ten patients with pseudotumor cerebri were studied. The diagnosis was based on bilateral papilledema and absence of intracranial masses and hydrocephalus. Based on the radiological findings, three groups of patients emerged: (A) Five patients with an empty sella. Four had an enlarged sella; (B) Two patients with a pit...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1982.tb06869.x
更新日期:1982-10-01 00:00:00
abstract::In Sweden, the annual incidence of surgery for hydrocephalus was 3.4 per 100,000 adults between the years 1996 and 1998. The most common indication for surgery was normal pressure hydrocephalus (NPH; 47%), followed by high-pressure hydrocephalus (27%). Seventy-three percent of the patients had communicating hydrocepha...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.2005.00451.x
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVES:We examined whether the apolipoprotein E (ApoE) allele epsilon4 influences imaging findings in stroke as assessed by diffusion- (DWI) and perfusion-weighted (PWI) magnetic resonance imaging, and MR angiography (MRA). METHODS:Eight ApoE epsilon4 carriers and 15 non-carriers with acute ischemic stroke in the ...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.2006.00654.x
更新日期:2006-11-01 00:00:00
abstract::3 patients with the condition of "painful legs and moving toes" are reported. The etiology was unknown in 2 of them, but in 1 patient the symptoms were temporarily relieved by surgery for a lumbar herniated disc. The movements restarted 6 months after surgery. EMG studies showed near rhythmical muscle action potential...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1982.tb04526.x
更新日期:1982-08-01 00:00:00
abstract::A two-phase epidemiological study of essential tremor was carried out by investigating a rural population aged over 40 years in 2 municipalities in southwestern Finland. In the first phase, the subjects answered a questionnaire as to whether they had experienced tremor during the month preceding the inquiry. In the se...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1982.tb03129.x
更新日期:1982-07-01 00:00:00
abstract::We investigated the EEG frequency distribution by quantitative EEG (QEEG) in 28 children with type 1 diabetes and 28 age- and sex-matched control children. Among the diabetic children, 15 had experienced episodes of severe hypoglycemia (SH group) and 13 had not experienced such episodes (non-SH group). The EEG analysi...
journal_title:Acta neurologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1600-0404.1996.tb00017.x
更新日期:1996-06-01 00:00:00
abstract:BACKGROUND:Neuropsychiatric symptoms are common in Parkinson's disease and may precede onset of motor symptoms. They are also known to increase caregiver's burden. OBJECTIVE:The aim of this study was to assess neuropsychiatric symptoms in a cohort of Nigerian patients with idiopathic Parkinson's disease and compare wi...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/ane.12062
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVES:The aim of this open label pilot study was to evaluate the efficacy and tolerability of levetiracetam (LEV) as 'de novo' monotherapy in children and adolescents with late onset childhood occipital epilepsy-Gastaut type (COE-G). MATERIAL AND METHODS:Twelve patients suffering from COE-G were enrolled in this ...
journal_title:Acta neurologica Scandinavica
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/j.1600-0404.2009.01264.x
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVES:We studied the in vitro production of variably MS-related cytokines from Sardinian MS and healthy donors bearing the two "Sardinian" MS-associated HLA-DR alleles: DR3 and DR4, with the purpose to evidentiate possible differences in their immune response. MATERIALS AND METHODS:ELISA were used for detection o...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1998.tb01740.x
更新日期:1998-11-01 00:00:00
abstract::An EEG study of 64 Danish Turner girls and age-matched controls was made. The characteristic findings in the basic EEG rhythms of Turner girls were: 1) alpha activity of more rapid frequency (10.5+ Hz), lower amplitude (-20 microV, lower amount (-30%) and diffuse areas, 2) beta activity of slower frequency (14-18 Hz),...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1985.tb00919.x
更新日期:1985-12-01 00:00:00
abstract::The present communication is devoted to investigating the possibility that in myotonic dystrophy (MyD) a decreased ATP utilization by the membrane may produce modifications in glycoprotein structure and/or in the supramolecular arrangement of some membrane proteins. The study was carried out a) by determining the memb...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1982.tb03119.x
更新日期:1982-06-01 00:00:00
abstract::Peripheral blood lymphocytes from 23 out of 27 (85%) patients with multiple sclerosis responded to MS brain homogenates by increased formation of active E-rosettes. Lymphocytes from only six out of 78 (8%) patients with other neurological diseases responded to MS brain homogenates. The possible value of the test in th...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1979.tb02910.x
更新日期:1979-03-01 00:00:00
abstract::Supernatants of peripheral blood lymphocytes (PBL), containing lymphokines, isolated from MS patients and healthy subjects were tested for demyelinating activity in organotypic culture of the rat cerebellum. PBL were isolated on Ficoll-paque gradient and cultures in RPMI 1640 medium for 72 h with or without phytohemag...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1986.tb07853.x
更新日期:1986-09-01 00:00:00
abstract:BACKGROUND:For most major antiepileptic drugs, neuropsychological side effects have been reported. Healthy volunteer studies have found that both carbamazepine and valproate impair aspects of verbal memory. OBJECTIVE:The aim of this study was to assess the effects of carbamazepine and valproate on verbal memory, in a ...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0404.2010.01452.x
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:Sparse information on dose-response characteristics for initial antiepileptic drug monotherapy in children with idiopathic generalized epilepsy (IGE) is available. The aim of this study is to characterize the therapeutic dose of valproate in children with newly diagnosed IGE. MATERIALS AND METHODS:Effect of...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.2009.01308.x
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVES:To evaluate pain, cervical range of motion (CROM) and cognitive symptoms as predictors for poor prognosis defined as sick leave 3 years later. MATERIAL AND METHODS:In 97 patients CROM, pain intensity and cognitive symptoms were measured immediately following trauma, at 6 months and 3 years. Patients were al...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.2009.01305.x
更新日期:2010-10-01 00:00:00
abstract::Neurotropin was found to reduce brain oedema in an experimental model of brain infarction in the guinea-pig. A randomized double-blind controlled trial with Neurotropin was performed in 220 patients admitted within 24 h after an acute ischemic stroke. 35 of the neurotropin and 41 of the placebo-randomized patients had...
journal_title:Acta neurologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1600-0404.1994.tb02643.x
更新日期:1994-05-01 00:00:00
abstract:OBJECTIVES:Epilepsia partialis continua (Kojewnikow's syndrome) can be classified into 2 groups. The 1st group had stable neurological deficit, and the 2nd group had slowly progressive neurological deficit. The latter usually manifests not tetraplegia, but hemiplegia. We describe 3 patients with epilepsia partialis con...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1997.tb00296.x
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVES:To examine through a meta-analysis whether a treatment strategy of surgery plus the routine medical management saves lives and reduces disability in survivors of primary supratentorial intracerebral hematoma compared to routine medical management alone. MATERIAL AND METHODS:Computerized bibliographic search...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章,meta分析
doi:10.1111/j.1600-0404.1997.tb00078.x
更新日期:1997-02-01 00:00:00
abstract::A microtechnique was established for the study of the limited numbers of cells available in CSF. The method allowed for the determination of the number of immunoglobulin-secreting cells (IgSC) as well as the quantitation of immunoglobulin or specific antibody secreted into the culture medium. Dose-response curves and ...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1986.tb07866.x
更新日期:1986-12-01 00:00:00
abstract::Out of a data pool of 1271 patients with Multiple Sclerosis (MS) a total of 109 cases are selected having a sole spinal symptomatology throughout the course of the disease. This group differs in three particular features from the non-spinal forms of MS: In this group there is a higher percentage of females, the age at...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1978.tb02832.x
更新日期:1978-02-01 00:00:00
abstract:OBJECTIVES:To investigate the association between tumor necrosis factor-alpha (TNF-alpha) G-308A, tumor necrosis factor-beta (TNF-beta) G+252A and interleukin-4 (IL-4) C-590T polymorphisms and susceptibility to multiple sclerosis (MS) development and clinical course of the disease. MATERIALS AND METHODS:Two hundred an...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.2006.00743.x
更新日期:2007-03-01 00:00:00
abstract::Several forms of treatment of lower urinary tract functional disorders have been attempted in children with myelomeningocele (MMC). Intravesical electrical stimulation was attempted in 10 patients. Urinary control was achieved in one and in the remaining 9 either the bladder was resistant to stimulation or the childre...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1987.tb07888.x
更新日期:1987-01-01 00:00:00
abstract::Twenty-one patients continued a double-blind crossover study to compare the prophylactic effect on migraine of propranolol and clonidine. The daily dosage of propranolol and clonidine was 160 mg and 100 microgram, respectively. Statistical analysis did not show any significant difference between the two drugs in respe...
journal_title:Acta neurologica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0404.1980.tb01504.x
更新日期:1980-06-01 00:00:00
abstract::From December 1976 through March 1982, 188 patients entered an open non-random study carried out on hospitalized patients with a history of transient ischemic attacks or amaurosis fugax. Ninety-two patients received peroral anticoagulants usually combined with heparin treatment during the first days of treatment, and ...
journal_title:Acta neurologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0404.1985.tb03232.x
更新日期:1985-06-01 00:00:00