Cognitive deterioration in adult epilepsy: clinical characteristics of "Accelerated Cognitive Ageing".

abstract：:Sympathetic denervation of the brain vessels was performed uni- or bilaterally in 13 adult rabbits, and cortical cold lesions were induced bilaterally 10-18 days afterwards. After a further 4-35 days the vascular and morphological changes in the lesion areas were studied histologically and with angiography. No differe...

journal_title：Acta neurologica Scandinavica

authors： West KA,Hassler O

更新日期：1976-09-01 00:00:00

abstract：:There has been considerable interest in the possible association between impaired glucose tolerance (IGT) and neuropathy. A systematic literature search (Medline) and review was here performed. Twenty-three studies were evaluated. Fourteen investigated for the presence of neuropathy in patients with IGT. Nine studied ...

journal_title：Acta neurologica Scandinavica

authors： Rajabally YA

更新日期：2011-07-01 00:00:00

abstract：:CSF cytology, immunocytochemistry and biochemical tumor markers were compared in 12 patients with a meningeal carcinomatosis regarding diagnostic significance and therapy control; 50 samples were investigated. Cytology was tumor-positive in 39 samples and immunocytochemistry in 45 samples. Intrathecally produced tumor...

journal_title：Acta neurologica Scandinavica

authors： Oschmann P,Kaps M,Völker J,Dorndorf W

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVES:Cognitive impairment is frequent in children with frontal lobe epilepsy (FLE). Its etiology remains unknown. With diffusion tensor imaging, we have studied cerebral white matter properties and associations with cognitive functioning in children with FLE and healthy controls. METHODS:Thirty children aged 8-1...

journal_title：Acta neurologica Scandinavica

authors： Braakman HM,Vaessen MJ,Jansen JF,Debeij-van Hall MH,de Louw A,Hofman PA,Vles JS,Aldenkamp AP,Backes WH

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:To describe clinical, electrophysiological and genetic data of five unrelated Sicilian pedigrees harbouring a heterozygous Ser78Leu mutation in the myelin protein zero (MPZ) extracellular domain. MATERIALS AND METHODS:Clinical, electrophysiological and genetic findings of 16 patients were reported. Polymorp...

journal_title：Acta neurologica Scandinavica

authors： Mazzeo A,Muglia M,Rodolico C,Toscano A,Patitucci A,Quattrone A,Messina C,Vita G

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVES:A highly adaptive aspect of human memory is the enhancement of explicit, consciously accessible memory by emotional stimuli. We studied the performance of Alzheimer's disease (AD) patients and elderly controls using a memory battery with emotional content, and we correlated these results with the amygdala an...

journal_title：Acta neurologica Scandinavica

authors： Schultz RR,de Castro CC,Bertolucci PH

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Multiple sclerosis (MS) is associated with Epstein-Barr virus (EBV) infection, but the relationship between the virus and the disease is not clear. As many different types of EBV exist, it is possible that MS is caused by one particular type of EBV. Objectives - The aim of this study was to determine whether...

journal_title：Acta neurologica Scandinavica

authors： Lindsey JW,Patel S,Zou J

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVES:This study aimed to investigate whether neurological disability status, heart rate variability (HRV), cardiorespiratory fitness (CRF) explained the variance in depressive symptoms in multiple sclerosis (MS). METHODS:Associations between CRF (via maximal oxygen uptake; VO2peak ), HRV indices of normalized ul...

journal_title：Acta neurologica Scandinavica

authors： Ensari I,Pilutti LA,Motl RW

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To clarify the relationship between mitochondrial DNA (mtDNA) sequence variations and phenotypes in patients with A3243G mutation. MATERIALS AND METHODS:We studied whole mtDNA sequences in two families with A3243G mutation and characteristic clinical features. Two brothers in Family 1 had shown thiamine defi...

journal_title：Acta neurologica Scandinavica

authors： Morovvati S,Nakagawa M,Sato Y,Hamada K,Higuchi I,Osame M

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that status epilepticus can lead to neuronal injury. However, the effect of a small number of isolated seizures is uncertain. METHODS:We used structural MRI and neuropathology to study the effects of isolated seizures induced by kainic acid (KA), (RS)-2-amino-3-(3-hydroxy-5-tert-...

journal_title：Acta neurologica Scandinavica

authors： Acosta MT,Munashinge J,Zhang L,Guerron DA,Vortmeyer A,Theodore WH

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:Although there is growing evidence for a relation between Parkinson syndrome (PS) and mitochondriopathy (MCP), little is known about the frequency of PS in MCP. MATERIAL AND METHODS:This study assessed the frequency of PS in patients with MCP, the phenotype of these patients, and their response to anti-Park...

journal_title：Acta neurologica Scandinavica

authors： Finsterer J

更新日期：2002-05-01 00:00:00

abstract：:Only 15% of patients with severe epilepsy with frequent partial seizures achieve any improvement in their seizure frequency by further drug treatment. As we know that epileptic seizures result in neuron loss with early development of mental deterioration, that the mortality rate of patients with epilepsy is increased ...

journal_title：Acta neurologica Scandinavica

authors： Dam M

更新日期：1996-08-01 00:00:00

abstract：:IgG and IgM concentrations in tears of multiple sclerosis patients (n = 38) are increased compared to normal controls (n = 23). The occurrence of oligoclonal tear IgG bands (7.9%)--as determined by immunoblotting--did not differ between groups. Our findings suggest an altered reactivity of the secretory immune system ...

journal_title：Acta neurologica Scandinavica

authors： Liedtke W,Weller M,Wiethölter H,Dichgans J

更新日期：1992-03-01 00:00:00

abstract：:The present paper reports a family settled in the northern part of Norway, with a hereditary neurological disorder consisting clinically of spastic paraplegia associated with neurogenic bladder disturbances and syndactylia. Nine out of 22 members in three generations exhibit these clinical features. The bladder distur...

journal_title：Acta neurologica Scandinavica

authors： Opjordsmoen S,Nyberg-Hansen R

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVES:Ischaemic stroke is one of the leading causes of death and disability worldwide. Although the secondary preventive medication should be continued for life, its use commonly declines in time. This may lead to recurrent vascular events. In this study, we investigated if during a long follow-up period discontin...

journal_title：Acta neurologica Scandinavica

authors： Rijkmans M,de Jong G,van den Berg JSP

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:To evaluate the contribution of the demographical, clinical, analytical and genetic factors to brain signal intensity changes in T2-weighted MR images in amyotrophic lateral sclerosis (ALS) patients and controls. METHODS:Susceptibility-weighted and FLAIR sequences were obtained in a 3T MR scanner. Iron-rela...

journal_title：Acta neurologica Scandinavica

authors： Vázquez-Costa JF,Mazón M,Carreres-Polo J,Hervás D,Pérez-Tur J,Martí-Bonmatí L,Sevilla T

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Early administration of paracetamol may improve outcome of patients with acute stroke and a baseline body temperature of 37°C or above by lowering body temperature and preventing fever. Besides its antipyretic effects, paracetamol may affect blood pressure through cyclooxygenase-2 inhibition. We therefore ai...

journal_title：Acta neurologica Scandinavica

authors： den Hertog HM,van der Worp HB,van Gemert HM,van Gijn J,Koudstaal PJ,Dippel DW

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:Our purpose was to identify the incidence and significance of markers of systemic connective tissue abnormalities (CTA) in patients with saccular intracranial aneurysms (SIA). MATERIALS AND METHODS:This prospective case-control study included 199 consecutive patients with SIA (103 women and 96 men, mean age...

journal_title：Acta neurologica Scandinavica

authors： Lebedeva ER,Sakovich VP

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:There has been a long-standing interest in the possible role of the hippocampus in autism and both postmortem brain and neuroimaging studies have documented varying abnormalities in this limbic system structure. AIMS:This study investigates the density of subsets of hippocampal interneurons, immunostained w...

journal_title：Acta neurologica Scandinavica

authors： Lawrence YA,Kemper TL,Bauman ML,Blatt GJ

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To assess hemispheric differences in the duration of focal onset seizures and its association with clinical and demographic factors. METHODS:A retrospective analysis was performed on adult patients with drug-resistant unifocal epilepsy, who underwent intracranial EEG recording between 01/2006 and 06/2016. Se...

journal_title：Acta neurologica Scandinavica

authors： Seethaler M,Lauseker M,Ernst K,Rémi J,Vollmar C,Noachtar S,Kaufmann E

更新日期：2020-10-04 00:00:00

abstract：:A group of asymptomatic HIV-infected patients (CDC II and III) was followed-up over a two year period with semi-annual neuropsychological testing. Of the total sample of 36 subjects, all were retested at test two (T2), 19 at test three (T3) and 13 at test four (T4). A subgroup of subjects was further tested on a simpl...

journal_title：Acta neurologica Scandinavica

authors： Karlsen NR,Reinvang I,Frøland SS

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVES:To investigate the effect of caudal zona incerta-deep brain stimulation (cZi-DBS) on word-level speech intelligibility in patients with Parkinson's disease, under both an optimal listening condition and a simulated more naturalistic listening condition. MATERIALS AND METHODS:Spoken single words were extract...

journal_title：Acta neurologica Scandinavica

authors： Johansson L,Möller S,Olofsson K,Linder J,Nordh E,Blomstedt P,van Doorn J,Karlsson F

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVES:Myotonic dystrophy type 1 (DM1) is caused by large expansions of cytosine-thymine-guanine (CTG)-repeats in myotonic dystrophy protein kinase (DMPK)-gene. This gene is highly polymorphic in healthy individuals. It has been proposed that expanded alleles originated from the group of large sized normal alleles....

journal_title：Acta neurologica Scandinavica

authors： Culjković B,Stojković O,Vukosavić S,Savić D,Rakocevic V,Apostolski S,Romac S

更新日期：2002-01-01 00:00:00

abstract：:The frequency of post-lumbar puncture headache (PLPH) was registered prospectively in 395 consecutive demented patients at a dementia diagnostic unit. The incidence of PLPH was low, occurring in only 8 patients (2.0%), the severity was mild, and the duration was less than 2 days in all cases but one. The reasons for t...

journal_title：Acta neurologica Scandinavica

authors： Blennow K,Wallin A,Häger O

更新日期：1993-09-01 00:00:00

abstract：:Electrophysiological examinations were done on 20 patients aged 40-71 years with recently diagnosed high grade non-Hodgkin's lymphomas. General chemotherapy and intrathecal chemotherapy in order to prevent central nervous system (CNS) involvement were begun. On the first day of chemotherapeutic cycle patients received...

journal_title：Acta neurologica Scandinavica

authors： Grzelec H,Fryze C,Nowacki P,Zdziarska B

更新日期：1996-10-01 00:00:00

abstract：:One cause of ischemic brain injury is free radical formation during recirculation. Allopurinol inhibits xanthine oxidase, an important source of free oxygen radicals. It is known that allopurinol pre-treatment has a protective action during cerebral ischemia. In the present study we exposed slices from the rat hippoca...

journal_title：Acta neurologica Scandinavica

authors： Hegstad E,Berg-Johnsen J,Langmoen IA

更新日期：1991-05-01 00:00:00

abstract：:Isoelectric focusing and agarose gel electrophoresis of CSF and serum revealed similar frequencies of oligoclonal bands in multiple sclerosis (100% with both methods), infectious CNS disorders (38 and 23%) and other neurological diseases (8 and 10%). In selected cases with unsure CSF oligoclonal bands on agarose gel e...

journal_title：Acta neurologica Scandinavica

authors： Laurenzi MA,Link H

更新日期：1978-09-01 00:00:00

abstract：:The activity of 7 mitochondrial enzymes, fumarase, NAD-malate dehydrogenase (MDH), citrate synthase (CS), valine dehydrogenase (VDH), succinate dehydrogenase (SDH), glutamate dehydrogenase (GDH), pyruvate dehydrogenase complex (PDHC) has been measured in platelet preparations from patients affected by Friedreich's ata...

journal_title：Acta neurologica Scandinavica

authors： Sorbi S,Piacentini S,Fani C,Tonini S,Marini P,Amaducci L

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVE:To replicate the treatment study by Behan et al. (1990) using current research criteria for Chronic Fatigue Syndrome (CFS). METHOD:Fifty patients who fulfilled the Oxford Criteria for CFS were randomly allocated to treatment with either Efamol Marine or placebo for 3 months. They were seen monthly and comple...

journal_title：Acta neurologica Scandinavica

authors： Warren G,McKendrick M,Peet M

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Thirty patients with glioblastoma multiforme (GBM) were treated by boron neutron capture therapy (BNCT) at the Studsvik facility in Sweden, in a clinical trial exploring a procedure in which 900 mg p-boronophenylalanine (BPA) per kilo body weight was infused in 6 h. OBJECTIVE:The present study was designed ...

journal_title：Acta neurologica Scandinavica

authors： H-Stenstam B,Pellettieri L,Sköld K,Rezaei A,Brun A

更新日期：2007-09-01 00:00:00